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119441
Risk of All-Cause Mortality in Mild Chronic Obstructive Pulmonary Disease: Evidence From the NHANES III and 2007–2012
Published 2025-01-01“…Weifeng Zou,1,2,* Jie Ou,1,2,* Fan Wu,3,4,* Shan Xiao,5 Zhishan Deng,3 Haiqing Li,3 Zihui Wang,3 Gaoying Tang,3 Shuling Liu,1 Dong Ye,6 Dongshuang Zhu,2 Jinxing Hu,1 Pixin Ran3,4 1State Key Laboratory of Respiratory Disease, Guangzhou Chest Hospital, Guangzhou, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Shufu County People’s Hospital, Kashgar region, Xinjiang, People’s Republic of China; 3State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Clinical Research Center for Respiratory Disease & National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China; 4Guangzhou National Laboratory, Guangzhou, People’s Republic of China; 5Department of Pulmonary and Critical Care Medicine, Shenzhen Longgang District Central Hospital, Shenzhen, People’s Republic of China; 6Department of Internal Medicine, Guangdong Province Second People’s Hospital, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fan Wu; Pixin Ran, State Key Laboratory of Respiratory Disease & Guangzhou Institute of Respiratory Health & National Center for Respiratory Medicine & National Clinical Research Center for Respiratory Disease & The First Affiliated Hospital of Guangzhou Medical University, 195 Dongfeng Xi Road, Guangzhou, 510120, People’s Republic of China, Email wu.fan@vip.163.com; pxran@gzhmu.edu.cnBackground: It is unclear whether patients with Global Initiative for Chronic Obstructive Lung Disease stage 1 (mild) chronic obstructive pulmonary disease (COPD) have a higher risk of all-cause mortality than participants with normal spirometry results.Methods: We used the data from the National Health and Nutrition Examination Survey (NHANES) III and 2007– 2012, which included participants aged 20– 79 years, to investigate whether patients with mild COPD (whole population and subgroups) have a higher risk of all-cause mortality than participants with normal spirometry. …”
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119442
CYTOKINES AND PROTEINS OF THE EXTRACELLULAR MATRIX IN THE BLOOD OF RATS OF DIFFERENT AGES AFTER FILLING THE DEFECT IN THE FEMORAL METAPHYSIS WITH ALLOGENEIC BONE IMPLANTS SATURATED...
Published 2023-10-01“…Based on the analysis of cytokines and proteins of the extracellular matrix in the blood serum of laboratory rats, to evaluate the course of metabolic processes after filling a defect in the femoral metaphysis with allogeneic bone implants saturated with MSCs. Material and Methods. On the model of a transcortical defect in the metaphysis of the femur, the content in the blood serum of 3 and 12 months white rats of interleukin-1 (IL-1), interleukin-6 (IL-6), transforming growth factor-b (TGF-b), osteocalcin (OC) and osteopontin (OP) on the 14th, 28th and 90 days was investigated. …”
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119443
Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma
Published 2025-01-01“…Abstract Objective This study investigates the impact of Titin (TTN) gene mutations on radiotherapy sensitivity in rectum adenocarcinoma (READ) by examining changes in the tumour immune microenvironment. Methods Data on gene expression and mutations in READ were obtained from The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) databases. …”
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119444
Comparison of GLP-1RAs vs Other Pharmacotherapy for Obesity
Published 2025-02-01“…Objectives: This review will summarize evidence comparing the safety and efficacy of GLP-1RAs or GLP-1RAs/GIP agonists with other pharmacologic treatments to achieve and maintain weight loss, improve quality of life, and reduce morbidity in obese adults. Methods: We completed a literature review of multiple databases, including PubMed, Embase, Google Scholar, and Cochrane databases, to identify studies about pharmacologic treatment for overweight or obese adults with or without T2DM and reporting outcomes of mean percentage body weight loss. …”
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119445
Inpatient dialectical behavior therapy combined with trauma-focused therapy for PTSD and borderline personality disorder symptoms: study design of the naturalistic trauma therapy s...
Published 2025-02-01“…Secondary outcomes are social functioning, quality of life, borderline and cluster C personality disorder symptoms as treatment predictors, treatment trajectories, clients’ experiences and health economic consequences.MethodsThe naturalistic, longitudinal Trauma Therapy Study is conducted from January 2019 until May 2025 in a mental healthcare center in the Netherlands. …”
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119446
Gender differences in associations between obesity and hypertension, diabetes, dyslipidemia: evidence from electronic health records of 3.5 million Chinese senior population
Published 2025-01-01“…We aimed to explore gender differences in associations between general/central obesity (body mass index/waist circumference) and hypertension, diabetes, dyslipidemia based on electronic health records of 3.5 million Chinese senior population over 65 years. Methods 3571189 electronic health records of Chinese senior population were collected from platform of Zhejiang provincial Basic Public Health Services Project. …”
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119447
Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis
Published 2025-01-01“…IntroductionThere is growing evidence that patients with SARS-CoV-2 (The severe acute respiratory syndrome coronavirus 2) may have a variety of cardiovascular complications in the post-acute phase of COVID-19, but these manifestations have not yet been comprehensively characterized.MethodsWe performed a systematic review and meta-analysis of primary research papers which evaluated individuals at least four weeks after confirmed COVID-19 diagnosis and reported on cardiovascular disease prevalence. …”
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119448
Satisfactory Evaluation of Call Service Using AI After Ureteral Stent Insertion: Randomized Controlled Trial
Published 2025-01-01“…ObjectiveThis study aimed to assess the effectiveness of an AI-based prediction tool in providing patients with information about potential complications from ureteroscopy and ureteric stent placement and indicating the need for early additional therapy. MethodsOverall, 28 patients (aged 20-70 years) who underwent ureteral stent insertion for the first time without a history of psychological illness were consecutively included. …”
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119449
Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling
Published 2025-01-01“…The aim of this study is to explore the mechanism of Kuiyangling in the treatment of ulcerative colitis.Methods: A mouse model of ulcerative colitis using 3% DSS water was considered, and model, normal, Kuiyangling medium- (5 g·kg− 1) and high-dose (10 g·kg− 1), and mesalazine (50 mg·kg− 1) groups were created. …”
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119450
Production performance of indonesian eel Anguilla bicolor bicolor with the addition of calcium carbonate (CaCO3) in to the culture media
Published 2016-02-01“…This study was conducted for 60 days, in which the eel were fed three times a day by at satiation method. The result of this study showed that treatment B with calcium carbonate addition of 50 mg/L in to the culture media was the best treatment for production performance (survival rate 99.1%; biomass growth rate 3.48 g/day; and food conversion ratio 3.5). …”
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119451
Vertical bacterial variability in oxidation ponds in the tropical zone
Published 2024-07-01“…The purpose of this study is to examine the vertical variability of bacteria in natural treatment oxidation ponds in tropical zones.METHODS: Wastewater samples were collected from an oxidation pond at 3 different depths (0–0.6, 0.6–1.5 and more than 1.5 meter), and their chemical, physical and biological qualities were analysed. …”
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119452
The influence of exercise modality and intensity on ventricular arrhythmia burden and perception of effort in patients with Arrhythmogenic Right Ventricular Cardiomyopathy with pla...
Published 2025-01-01“…To describe ARVC patients' average and peak ventricular arrhythmia burden – estimated from the prevalence of premature ventricular contractions (PVC) – measured during and after different exercise modalities and intensities, in context with cardiac and physiological load. Methods Twenty ARVC patients (8 f/12 m, age 48 ± 15 years, BMI 24 ± 3 kg/m2, resting PVC burden 4 ± 4%) with a heterozygous pathogenic/likely pathogenic plakophilin-2 (PKP-2) variant prospectively performed different exercises while monitored via 12-lead ECG. …”
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119453
The current state of the quality of homeopathic clinical research
Published 2025-03-01“…Further, we convened an international panel of nine experts in research methods and homeopathy to identify gaps in homeopathic research and prioritize areas for future study.We reviewed 99 clinical research studies targeting a wide range of populations and conditions. …”
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119454
Deep-Learning-Based Reconstruction of Single-Breath-Hold 3 mm HASTE Improves Abdominal Image Quality and Reduces Acquisition Time: A Quantitative Analysis
Published 2025-01-01“…The purpose of this prospective study was to improve image quality and accelerate imaging acquisition by using single-breath-hold T2-weighted HASTE with deep learning (DL) reconstruction (DL-HASTE) with a 3 mm slice thickness. <b>Method:</b> MRI of the upper abdomen with DL-HASTE was performed in 35 participants (5 healthy volunteers and 30 patients) at 3 Tesla. …”
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119455
Optimization of Dual-energy Spectral Lower-extremity Computed Tomography Venography Scanning Protocol: Phantom Study
Published 2025-01-01“…Objective: To optimize a scanning protocol for dual-energy spectral lower-extremity computed tomography venography (CTV) based on a phantom study. Methods: Test plugs were placed in the cavities of an energy CT quality-control phantom to simulate clinical scenarios. …”
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119456
Treatment Efficacy of Open Kinetic Chain Combined with Closed Kinetic Chain Exercise Training on Patients after Anterior Cruciate Ligament Reconstruction
Published 2023-12-01“…ObjectiveTo observe the effect of open kinetic chain (OKC) combined with closed kinetic chain (CKC) exercise training on motor function of knee or lower limb, balance function, quadriceps isokinetic muscle strength and atrophy degree after anterior cruciate ligament (ACL) reconstruction.MethodsA total of 84 patients who underwent knee ACL reconstruction in the Jinan Zhangqiu District People's Hospital from January 2020 to October 2021 were randomly divided into OKC group, CKC group, equal combination group and adjusted combination group, with 21 cases in each group. …”
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119457
ДОСЛІДЖЕННЯ ВПЛИВУ СОЦІАЛЬНИХ МЕРЕЖ НА ХАРЧОВУ ПОВЕДІНКУ КОРИСТУВАЧІВ СОЦІАЛЬНИХ МЕРЕЖ
Published 2024-12-01“…To implement a study of the impact of social media on the eating behavior of social media users with further analysis of the factors that influence changes in eating behavior through social media. Methods. An empirical study was conducted using comparative analysis. …”
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119458
The influence of the El Niño phenomenon on appearance of large-scale forest fires and their ecological consequences
Published 2024-07-01“…Comparative assessment of the ecological consequences of large-scale forest fires stimulated by natural and anthropogenic impacts (using the example of Ukraine and Chile in 2014–2024). Methods. Analytical review of the research problem, systems analysis of a number of accompanying processes, mathematical modeling and theoretical calculations. …”
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119459
Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution
Published 2023-11-01“…Therefore, the roles played by the microbes in the rumen microbial ecosystem are fundamental to developing innovative methods to modulate the rumen microbiome to improve buffalo production while reducing environmental impact. …”
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119460
The CYP4/20-HETE/GPR75 axis in the progression metabolic dysfunction-associated steatosis liver disease (MASLD) to chronic liver disease
Published 2025-01-01“…Both secreted levels of 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acid (EET) are elevated in patients with liver cirrhosis.MethodsCLD samples were evaluated for changes in free fatty acids (FFA), cholesterol, bilirubin, bile acid, reactive oxygen species (ROD), lipid peroxidation, myeloperoxidase activity and hydroxyproline levels to evaluate the degrees of liver damage and fibrosis. …”
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