Key Performance Indicators in Freestyle Swimming: Comparing Start, Turn, and Swimming Velocity in Top-Elite Female Junior and Adult Swimmers by Chantal Widmer, Julia Hernandez, Michael Romann, Wolfgang Taube, Dennis-Peter Born

“… Introduction Due to the increasing importance of start and turn performance in swim races throughout the recent years, the aim of the study was to compare the effect of start performance, turn performance, and swimming velocity on the race result between top-elite female junior and adult swimmers across all distances of freestyle pool races (50 m to 1500 m) and to provide a software tool to predict race outcomes based on the various key performance indicators. Methods In the present study, a total of 289 individual freestyle races from female participants at the European long-course championship, as well as 391 freestyle races at the Junior European long-course championship were analysed. …”
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Identification of Inflammatory Biomarkers for Predicting Peripheral Arterial Disease Prognosis in Patients with Diabetes by Kian Draper, Ben Li, Muzammil Syed, Farah Shaikh, Abdelrahman Zamzam, Batool Jamal Abuhalimeh, Kharram Rasheed, Houssam K. Younes, Rawand Abdin, Mohammad Qadura

“…We developed a predictive model using five identified biomarkers to predict major adverse limb events, limb loss, diabetic (DM) foot ulcers, and vascular intervention in patients with underlying PAD and DM over 2 years. Methods: A single-center prospective case control study with was conducted with 2 years’ follow up. …”
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Adverse reactions of botulinum toxin type A for treating strabismus in children by E.E. Sidorenko, I.A. Ostanina, K.N.M. Rosel’o, D.V. Migel, E.I. Sidorenko

“…</i> </p> <p> <i><b>Patients and Methods: </b>212 children (424 eyes) aged seven months to 15 years with estab-lished strabismus were enrolled. …”
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Identification of Lauric Acid as a Potent Sodium Channel NaV1.5 Blocker from Compound Chinese Medicine Wenxin Keli by Xie W, Gao J, Liang Y, Huang C, Zhang B, Chen X, Yao X, Nan G, Wu H, Wang Y, Wu L, Wang T, Zhu Y

“…This study focused on identifying the active inhibitor of INa in WXKL and exploring their mode of action in electrophysiological conduction.Methods: A chemical fraction library was constructed from an aqueous extract of WXKL and screened using an automated patch-clamping system in cells stably expressing the NaV 1.5 gene SCN5A. …”
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Thiol-Disulfide Homeostasis in Noise-Induced Hearing Loss in Rats by Enes Aydın, Serpil Mungan Durankaya, Osman Yilmaz, Günay Kirkim, Safiye Aktaş, Salim Neşelioğlu, Özcan Erel, Yüksel Olgun, Abdullah Dalgıç

“…Background: This study was designed to assess if thiol-disulfide homeostasis could be used as diagnostic biomarker in noise-induced hearing loss (NIHL) in a laboratory animal model. Methods: The study was carried out with a total of 28 female albino rats in 4 groups: group 1 (control group) included rats that were not exposed to noise or any study treatment; in group 2, following noise exposure, rats received 2 mg of dexamethasone per kilogram of body weight via the intramuscular route for 5 days; in Group 3, rats were exposed to noise and received a saline solution for 5 days, in a volume (0.15 cc) matched to that of dexamethasone administered in group 2; and in group 4, rats were exposed to noise, and blood samples were collected during the early phase to assess thiol-disulfide homeostasis without administering any treatment. …”
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Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women by Alice Tassi, Ambrogio P Londero, Anjeza Xholli, Giulia Lanzolla, Serena Bertozzi, Luca Savelli, Federico Prefumo, Angelo Cagnacci

“…It primarily measures osteocalcin and additionally examines other bone health markers, seeking to determine their responses to estrogen–progestogen treatments. Methods: This study involved a comprehensive evaluation of the pertinent literature and a meta-analysis explicitly conducted on data describing women of reproductive age. …”
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Evaluating the Impact of Pharmacotherapy in Augmenting Quit Rates Among Hispanic Adults in an App-Delivered Smoking Cessation Intervention: Secondary Analysis of a Randomized Contr... by Margarita Santiago-Torres, Kristin E Mull, Brianna M Sullivan, Ana Paula Cupertino, Ramzi G Salloum, Matthew Triplette, Michael J Zvolensky, Jonathan B Bricker

“…We then examined whether the use of any pharmacotherapy (ie, nicotine replacement therapy [NRT], varenicline, or bupropion) and NRT alone augmented each app-based intervention efficacy. MethodsParticipants reported using pharmacotherapy on their own during the 3-month follow-up and cigarette smoking abstinence at the 12-month follow-up via web-based surveys. …”
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EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer by Yongbin Zheng, Dan Song, Ming Guo, Chenhong Wang, Mingzhen Ma, Gongcai Tao, Licui Liu, Xiaobo He, Fengyu Cao, Dan Luo, Qingchuan Zhao, Zhongyuan Xia, Yanxin An

“…Consequently, an integrated transcriptomic analysis is necessary to fully elucidate the role of NAT10-mediated ac4C modifications in CRC progression. Methods NAT10 expression levels were analyzed in CRC samples and compared with those in corresponding normal tissues. …”
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Effect of different photoperiods on growth indices of female sterlet sturgeon, Acipenser ruthenus by Bahman Meknatkhah, Masoud Sattari, Bahram Falahatkar, Samaneh Poursaeid

“…Sterlet sturgeon, Acipenser ruthenus is a sturgeon species native in northern latitudes with shorter light periods, however, due to high performance in rearing, it has been distributed in different regions of the world with different latitudes. Materials and methods: This study was carried out to examine the effects of various photoperiods on growth indices and survival rate of female sterlet sturgeon broodstock. …”
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The Effect of Coronary Artery Disease on the Prognosis of Hypertrophic Cardiomyopathy: A Multi-Center Cohort Study by Guoqing Hou, Qian Liao, Huihui Ma, Yan Shu, Shengzhi Zeng, Yongmei Zhou, Liangjun Luo, Gang Zhao, Tao He, Mingjiang Liu, Jianhong Tao, Wei Hua, Xiaoping Li

“…This real-world cohort study was conducted to evaluate the prognosis of patients with patients with CAD. Methods: This cohort study of patients with HCM was conducted from May 2003 to September 2021. …”
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Technical note: Towards atmospheric compound identification in chemical ionization mass spectrometry with pesticide standards and machine learning by F. Bortolussi, H. Sandström, F. Partovi, F. Partovi, J. Mikkilä, P. Rinke, P. Rinke, P. Rinke, P. Rinke, M. Rissanen, M. Rissanen

“…We then trained two machine learning methods on these data: (1) random forest (RF) for classifying if a pesticide can be detected with CIMS and (2) kernel ridge regression (KRR) for predicting the expected CIMS signals. …”
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Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19: A multicenter, randomized, double-blind, phase 1b trial by Norberto Chavez-Tapia, Muneeba Ahsan Sayeed, Shobha Luxmi, Douglas J. Kasper, Fenchao Xue, Yang Shen, Weiliang Fan, Wei Yuan, Bin Du

“…This study was conducted to evaluate the safety and efficacy of a potent and selective inhibitor of RIPK1, SIR1-365, in hospitalized patients with severe coronavirus disease 2019 (COVID-19). Methods: This multicenter, randomized, double-blind, phase 1b study screened patients from December 18, 2020 until November 27, 2021. …”
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Caesalpinia sappan L. ethyl acetate extract regulated angiogenesis in atherosclerosis by modulating the miR-126/VEGF signalling pathway by Yue He, Chao Huang, Jingjing Chen, Weizeng Shen

“…Aims of the study: To investigate the regulatory mechanism of Caesalpinia sappan L. ethyl acetate extract (CSEAE) on angiogenesis in atherosclerosis (AS) based on the miR-126/VEGF signalling pathway. Materials and methods: Our study first screened for differentially expressed microRNAs (miRNAs) associated with AS using the Gene Expression Omnibus (GEO) public database at the National Center for Biotechnology Information (NCBI) and R language software. …”
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Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation by Meng Zhang, Meng Zhang, Xiaomei Zhang, Xiaomei Zhang, Jiaxi Wang, Wenyi Lu, Xia Xiao, Hairong Lyu, Xiaoyuan He, Yedi Pu, Juanxia Meng, Cuicui Lyu, Xinping Cao, Mingfeng Zhao, Mingfeng Zhao

“…In this study, we aimed to evaluate the efficacy and safety profile of donor-derived CLL-1 CAR-T cells in AML patients who experienced relapsed post-transplantation.Methods14 AML patients who experienced relapse following allogeneic HSCT were enrolled in our clinical trial. …”
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Transcutaneous spinal cord stimulation combined with robotic-assisted body weight-supported treadmill training enhances motor score and gait recovery in incomplete spinal cord inju... by Natalia Comino-Suárez, Juan C. Moreno, Álvaro Megía-García, Antonio J. del-Ama, Diego Serrano-Muñoz, Juan Avendaño-Coy, Ángel Gil-Agudo, Mónica Alcobendas-Maestro, Esther López-López, Julio Gómez-Soriano

“…Objective To determine the effectiveness of tSCS combined with robotic-assisted gait training (RAGT) on lower limb muscle strength and walking function in incomplete spinal cord injury (iSCI) participants. Methods A randomized, double-blind, sham-controlled clinical trial was conducted. …”
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Ascorbic acid-containing compound efficacy in ischemic brain damage by Rita M. Termulaeva, Konstantin Y. Belanov, Natalya D. Bunyatyan, Aleksander S. Pirozhkov, Dmitrii E. Timoshkin, Ekaterina V. Blinova, Olga V. Vasilkina, Kirill D. Blinov, Elena V. Semeleva, Aleksander A. Dmitriev, Dmitrii S. Blinov

“…The aim: to assess anti-ischemic activity of 3-hydroxypyridine ascorbate in the in vitro and in vivo models of brain cell and tissue response to ischemia and reoxygenation. Materials and Methods: 3-hydroxypyridine ascorbate (laboratory code 3-EA) was assessed as chemical substance (purity 99.8%) diluted in sterile phosphate-buffered saline. …”
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Temperatura de superficie en el Valle del Río Neuquén Utilizando Imágenes LANDSAT by Marisa Gloria Cogliati

“…Abstract Studies of surface and air temperature from LANDSAT need a great density of meteorological stations following the altitudinal variation and complexity of terrain. Alternative methods for the study of the spatial distribution are useful. …”
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Kualitas Air Sumur Gali Kelurahan Lubuk Buaya Kecamatan Koto Tangah Kota Padang Berdasarkan Indeks Most Probable Number (MPN) by Randa Novalino, Netti Suharti, Arni Amir

“…The research was conducted in two stages, dug well water samples as well as observation of the factors that affect water quality and microbiological examination of the Most Probable Number method (MPN) Test. This test consists of presumptive tests and confirmative tests that </em><em>were</em><em> tailored to regulation of Indonesian health minister.  …”
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أسلوب التعامل مع الخلافات الفقهية: مراجعة كتاب الموافقات للإمام الشاطبي. دار الكتب العلمية، ٢٠٠٥، ٥٨٠ صفحة، ISBN: ٢-٧٤٥١-١٥٣٠-٨، (غلاف صلب)... by Muhammad Najib Abdullah, Muhammad Nazir Alias, Syaryanti Hussin, Ibrahim Zakariyya Moosa

“…This study employs an inductive-analytical approach, tracing and analyzing the relevant content in al-Shātibī's al-Muwāfaqāt, as well as a comparative method to contrast Imam al-Shatibi's views with those of others, in order to highlight his contributions and limitations, and validate the findings. …”
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A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial by Colleen Stiles-Shields, Karen M. Reyes, Tanvi Lakhtakia, Shannon R. Smith, Olga E. Barnas, Elizabeth L. Gray, Charles J. Krause, Kaylee P. Kruzan, Mary J. Kwasny, Zara Mir, Sameer Panjwani, Steven K. Rothschild, Lisa Sánchez-Johnsen, Nathan W. Winquist, Emily G. Lattie, Nicholas B. Allen, Madhu Reddy, David C. Mohr

“…The current study: (1) developed a TES tailored for Primary Care patients with depression and/or anxiety, and (2) conducted a pilot randomized controlled trial to assess the efficacy of the TES compared to a digital psychoeducation control app. Methods Participants were randomized to either: (1) TES: the “Vira” smartphone app (Ksana Health Inc.), informed by behavioral activation and using passive sensing technology to provide behavioral “insights” and target behaviors associated with mental health symptoms, alongside lay-provider coaching, or (2) Control: the Mood Education mobile app (ME), containing static psychoeducational resources designed to target mental health symptoms. …”
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