Association of ambient air pollutants with blood physiological and biochemical indicators and systemic immune inflammation index in people living around Beijing: an analysis of air... by Bingqian DU, Zhiqiang REN, Peian CHEN, Zhenjun LI

“…ObjectiveTo investigate the association of ambient air pollutants with blood physiological and biochemical indicators and systemic immune inflammation index in people living around the Beijing metropolitan area and to provide a basis for formulating intervention policies on the health hazards of air pollution. MethodsData on demographics and blood physiological and biochemical indicators of 1 150 residents (8 – 90 years old) living around the Beijing metropolitan area, as well as monitoring data of air pollutants in the area for the period of 2018 – 2019, were collected from the Air Pollution and Population Health Database of the National Population Health Science Data Center. …”
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Facing migration under adverse conditions: challenges and resilience in the Colombo-Venezuelan border area by Gloria Omaira Bautista, Axel Kroeger, Nelly Rosero Castillo, Eduardo Gabriel Osorio Sanchez, Dianne Sofía Gonzales Escobar, Rafael Olarte, Sonia Diaz Monsalve

“…The massive influx of Venezuelan migrants into Colombia for more than a decade has characteristics which warrant a systematic analysis to identify contextual and individual factors favouring and hindering the well-being of migrants and their new Colombian neighbours of the receptor population. Methods A household interview survey was conducted in two cities of the Colombo-Venezuelan border: Cucuta and Valledupar. …”
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Safety and efficacy of catheter ablation in atrial fibrillation patients with heart failure with preserved ejection fraction by Songbing Long, Yuanjun Sun, ShiYu Dai, Xianjie Xiao, Zhongzhen Wang, Wei Sun, Lianjun Gao, Yunlong Xia, Xiaomeng Yin

“…Hypothesis CA for AF in HFPEF patients may not increase the complications and had similarly the rate of freedom from AF vs. patients without HFPEF, and it may reduce hospitalizations and mortality and improve heart function VS medical treatment. Methods Three groups of AF patients were included in the study: 187 patients with HFPEF for their first CA (AFPHF-CA), 187 patients with HFPEF who were undergoing medical therapy (AFPHF-Med), and 196 patients without HFPEF for their first CA (AF-CA). …”
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Meibomian gland alterations in allergic conjunctivitis: insights from a novel quantitative analysis algorithm by Jingting Wei, Jingting Wei, Kunhong Xiao, Qingyuan Cai, Qingyuan Cai, Shenghua Lin, Xiangjie Lin, Yujie Wang, Yujie Wang, Jiawen Lin, Kunfeng Lai, Yunxi Ye, Yuhan Liu, Li Li

“…PurposeTo investigate the changes in meibomian gland (MG) structure in allergic conjunctivitis (AC) patients using an intelligent quantitative analysis algorithm and to explore the relationship between these changes and clinical parameters.MethodsA total of 252 eyes from patients with AC and 200 eyes from normal controls were examined. …”
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Eosinophil is a predictor of severe immune-related adverse events induced by ipilimumab plus nivolumab therapy in patients with renal cell carcinoma: a retrospective multicenter co... by Yoshihiko Tasaki, Shuzo Hamamoto, Shimpei Yamashita, Junya Furukawa, Kazutoshi Fujita, Ryotaro Tomida, Makito Miyake, Noriyuki Ito, Hideto Iwamoto, Yoshihisa Mimura, Yosuke Sugiyama, Rei Unno, Atsushi Okada, Takahiro Yasui, Yoko Furukawa-Hibi

“…Therefore, this study aimed to investigate the association between eosinophil and severe irAEs in patients receiving ipilimumab plus nivolumab therapy for RCC.MethodsIn this retrospective study, 161 patients receiving ipilimumab plus nivolumab therapy for RCC were divided into three groups based on whether they experienced <grade 2 irAEs (non-severe irAE group), ≥grade 3 irAEs (severe irAE group), or not (non-irAE group). …”
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Effects of intermittent oral-esophageal tube feeding for patients with post-stroke dysphagia: A Meta-analysis (间歇性经口至食管管饲用于脑卒中后吞咽障碍患者疗效的Meta分析)... by QU Jianni (屈简妮), JIAO Meng (焦萌), GUO Hong (郭红), CHEN Shanshan (陈闪闪)

“…Objective To evaluate the effects of intermittent oral-esophageal tube feeding for patients with post-stroke dysphagia. Methods Researches had searched CNKI, Wanfang Database, VIP, CBM, PubMed, Web of Science, Embase, The Cochrane Library, Scopus, OVID and CINAHL, and references of included studies were searched, from inception to June 2022. …”
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Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner by Dan-dan Xiong, Zhen-dong Chen, Jian-di Li, Yu-long Deng, Rong-quan He, Zhi-guang Huang, San-qi An, Yi-wu Dang, Gang Chen

“…However, the underlying mechanisms, especially the possible involvement of the m6A pathway, remain to be elucidated. Methods HCC cell and zebrafish xenograft models were utilized to validate the anti-HCC effects of NC. …”
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Application of modified nursing shift schedule based on SBAR communication model in perioperative management of patients with early gastric cancer (基于SBAR模式改良护理交班表在早期胃癌患者围手术期管理中的应用... by DANG Limei (党李梅), GUAN Chengguo (管成果), ZAI Xiaojuan (宰小娟)

“…Objective To evaluate the effect of modified nursing shift schedule based on SBAR communication model in perioperative management of patients with early gastric cancer. Methods Totally 100 patients who received endoscopic submucosal dissection (ESD) for early gastric cancer between January and May 2021 were included as the control group, another 100 patients who received ESD for early gastric cancer between August and December 2021 were included as the observation group. …”
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Hubungan antara Higiene Perorangan dengan Infeksi Cacing Usus (Soil Transmitted Helminths) pada Siswa SDN 25 dan 28 Kelurahan Purus, Kota Padang, Sumatera Barat Tahun 2013 by Rizka Yunidha Anwar, Nuzulia Irawati, Machdawaty Masri

“…This study used an observational analytic design method of cross -sectional study on 122 students in grade 1 to grade 6 in 25 and 28 primary school Purus, Padang in December 2013. …”
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Therapeutic effect of dihydroartemisinin on Alzheimer’s disease model mice with senile macular degeneration by Gao Han, Gong Xuewu, Zhang Meng, Wang Yuejing, Wang Yuchun, Zhang Keshuang, Yao Hongbo

“…Abstract Objectives This study focuses on the preventive and therapeutic effects of Dihydroartemisinin (DHA) on Alzheimer’s disease (AD) model mice and the effects of DHA and donepezil on amyloid β-protein deposition and autophagy in nerve cells. Methods Six autophagy related targets were selected for molecular docking with DHA to predict the affinity between DHA and the target. …”
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Comparison of Influence of Office and 24‐h Central Aortic Blood Pressure on Target Organ Damage in Hypertension by Yueliang Hu, Hui Yang, Guili Chang, Yaya Bai, Alberto Avolio, Qian Wang, Shenshen Gao, Junli Zuo

“…Office AIx and cPP were more strongly correlated with c‐fPWV than 24‐h measurements while cSBP, DBP, and cPP obtained by both methods were equally correlated with c‐fPWV. Ambulatory central (aortic) pressure may be more strongly related to HMOD than office CAP which may have an advantage in screening for c‐fPWV. …”
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«HO CAPITO! LA FRASE È COME UN’ORCHESTRA E IL VERBO È IL DIRETTORE D’ORCHESTRA!» GRAMMATICA VALENZIALE ALLA SCUOLA SECONDARIA DI I GRADO. by Miriam Flora Gnech

“…The model followed in this paper has been developed by the “Paduan study group”, that starting from Sabatini’s model and makes some adaptations based on the proposals of Vanelli and Prandi, De Santis. The method used is inductive, following the example of Lo Duca’s Esperimenti grammaticali (2004): the observation of authentic linguistic data and the guidance of well thought-out and effective questions posed by the teacher lead the learners to make “discoveries” and to participate in the construction of rules and definitions. …”
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Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients by C Wheeler, C Masimirembwa, B Mthembu, J Botha, J Scholefield, J Fabian

“…To compare the pharmacokinetics of tacrolimus in paediatric liver transplant recipients with their donors’ CYP3A5 genotypes, considering both donor and recipient characteristics. Methods. Blood samples from 46 living liver donors were collected, their genomic DNA was extracted, and their CYP3A5 genotype was established (polymerase chain reaction and restriction fragment length polymorphism analysis, validated by Sanger sequencing). …”
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Performance of the modified 2022 ACR/EULAR giant cell arteritis classification criteria without age restriction for discriminating from Takayasu arteritis by Takahiko Sugihara, Masayoshi Harigai, Haruhito A. Uchida, Hajime Yoshifuji, Yasuhiro Maejima, Jun Ishizaki, Yoshiko Watanabe, Hiroaki Dobashi, Yoshinori Komagata, Naoto Tamura, Yoshikazu Nakaoka, Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS)

“…Abstract Objective To evaluate the ability to discriminate giant cell arteritis (GCA) from Takayasu arteritis (TAK) according to the modified 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) GCA classification criteria. Methods Patients enrolled in the Japanese nationwide retrospective registry were evaluated using the criteria with partial modification; wall thickening of descending thoracic-abdominal aorta were mainly diagnosed by contrast-enhanced computed tomography (CT) or magnetic resonance imaging instead of evaluating with positron emission tomography (PET)-CT. …”
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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma by Victoria Jennings, Kevin Harrington, Hardev Pandha, Alan Melcher, Adel Samson, Fiona Errington-Mais, Victoria Roulstone, Eva Crespo-Rodriguez, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Martin McLaughlin, Malin Pedersen, Richard Vile, Joan Kyula, Jehanne Hassan, Lizzie Appleton, Charleen ML Chan Wah Hak, Gabby Baker, Edward Armstrong, Matthew Chiu, Masahiro Ono

“…Background Combination herpes simplex virus (HSV) oncolytic virotherapy and BRAF inhibitors (BRAFi) represent promising immunogenic treatments for BRAF mutant melanoma, but an improved understanding of the immunobiology of combinations is needed to improve on the benefit of immune checkpoint inhibitors (ICI).Methods Using a BRAFV600E-driven murine melanoma model, we tested the immunogenicity of HSV/BRAFi in immunocompetent C57BL mice. …”
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Prevalence of Respiratory Syncytial Virus Infection in Hospitalized COPD Patients in Spain Between 2018–2022 by Rosa María Gómez-García, Javier De-Miguel-Díez, Ana López-de-Andrés, Valentín Hernández-Barrera, Ana Jimenez-Sierra, Natividad Cuadrado-Corrales, José J. Zamorano-León, David Carabantes-Alarcón, Andrés Bodas-Pinedo, Rodrigo Jiménez-García

“…Objective: To analyze the hospitalizations of patients with COPD and RSV infection in Spain between 2018 and 2022. Methods: The data used were obtained from the Spanish Hospital Discharge Database. …”
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Kombinasi Intent Classification dan Named Entity Recognition pada Data Berbahasa Indonesia dengan Metode Dual Intent and Entity Transformer by Zahra Asma Annisa, Rizal Setya Perdana, Putra Pandu Adikara

“…One application of artificial intelligence for service excellence is the use of a chatbot, which requires an appropriate method for the classification of user intent and Named Entity Recognition (NER). …”
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Informasi Dini Terhadap Penyakit Kanker Payudara berbasis Telepon Pintar by Hesti Lina Wiraswati, Savira Ekawardhani, Sarasati Windria, Arina Al Khaq, Fauzia Nurfitri, Dini Wahyuni, Nadya Rachmawati, Rusdi Toriq Baasin, Annissa Retno Arimdayu, Annisa Retno Arimdayu

“…Objective: To provide information service about breast cancer, and an explanation also simulation of how to do BSE based on a smartphone-based app. Methods: The research consists of application design, collection of assets as a database source, application validation, and testing to 100 respondents using purposive technique sampling. …”
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The relationship between social support and depression among older adults with hypertension in urban communities: mediating effects of coping styles by Dan Li, Jin-Hua Jie, Hong Li, Xue-Mei Xia, Yilin Zhang, Yilin Zhang, Yan Yang, Yan Yang, Jianjun Xiang, Jianjun Xiang, Jianjun Xiang, Hai-Lin Zhuang

“…This study aimed to explore the inter-relationships between social support, coping style and depression in older hypertensive patients within a community setting, and to investigate the mediating effects of coping style.MethodsA cross-sectional questionnaire survey was conducted with 4211 older hypertensive patients from Fuzhou, Fujian Province, China. …”
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Effect of a high dose atorvastatin as adjuvant therapy to mesalamine in attenuating inflammation and symptoms in patients with ulcerative colitis: a randomized controlled pilot stu... by Sumaiah J. Alarfaj, Sahar M. El-Haggar, Sahar K. Hegazy, Sahar K. Hegazy, Maha M. Maher, Maha M. Maher, Monir M. Bahgat, Thanaa A. Elmasry, Sarah Alrubia, Amsha S. Alsegiani, Mostafa M. Bahaa

“…Activation of sphingosine 1 phosphate (S1P)/ tumor necrosis factor-alpha (TNF-α)/ interleukin-6 (IL-6) pathways has been confirmed in the pathogenesis of UC and preclinical studies proved the efficacy of atorvastatin on these pathways.AimTo investigate the role of atorvastatin on S1P/TNF-α/IL-6 pathway in UC.MethodsPatients with mild to moderate UC were allocated into two groups in this pilot study. …”
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