Socioeconomic indicators related to the global burden of breast cancer in women in 2020: an analysis of WHO data by Tingting XU, Ruoyu YANG, Jingjing LI, Yiying FANG

“…ObjectiveTo understand the socioeconomic factors that influence the global burden of breast cancer in women and to provide a reference for further optimization of breast cancer prevention, screening, and treatment strategies. MethodsData on the global age-standardized incidence rate (standardized incidence rate) and global age-standardized mortality rate (standardized mortality rate) of breast cancer in women from 175 countries around the world in 2020 were collected from the World Health Organization's Cancer Tomorrow database. …”
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Assessing the role of genotype by environment interaction of winter wheat cultivars using envirotyping techniques in North China by Haiwang Yue, Yanbing Wang, Zhaoyang Chen, Jiashuai Zhu, Partha Pratim Behera, Pengcheng Liu, Haoxiang Yang, Jianwei Wei, Junzhou Bu, Xuwen Jiang, Xuwen Jiang, Wujun Ma

“…Accurate yield estimation depends on understanding the patterns of GEI in multi-environment trials (METs).MethodsFrom 2014 to 2018, continuous experiments were conducted in the Heilonggang region of the North China Plain (NCP), evaluating 71 winter wheat genotypes across 16 locations over five years. …”
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Decreased sirtuin 1 in type 2 diabetes patients with abnormal BMD by Yao Xu, Tianxiao Hu, Peiwu Jiang, Xiujing Wang, Jiaqi Yao, Huiling Shen, Zhenying Zhang, Bojing Zheng, Ting Wang, Yanxia Ren, Jing Wang, Qingying Tan

“…This study investigates the relationship between Sirtuin 1 levels, BMD, and bone metabolism in newly diagnosed T2DM patients, specifically examining alterations in Sirtuin 1 levels in those with concomitant osteoporosis or osteopenia.MethodsA total of 69 newly diagnosed T2DM patients and 82 control subjects with normal glucose tolerance (NGT) were enrolled. …”
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New multilocus sequence typing scheme for Enterococcus faecium reveals sequential outbreaks of vancomycin-resistant E. faecium ST1162 and ST610 in a Japanese tertiary medical cente... by Masaki Karino, Masashi Yanagihara, Tetsuya Harada, Megumi Sugo, Mizuki Karino, Hirofumi Ohtaki, Hiroyuki Hanada, Toru Takano, Masaya Yamato, Shigefumi Okamoto

“…Designed using Czech isolates, this scheme showed comparable discriminatory powers with the traditional method for geographically distinct Japanese isolates and clearly visualized outbreaks. …”
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Associations of dose to the urethra and long-term patient-reported outcomes after radiotherapy with EBRT and HDR brachytherapy boost for prostate cancer by Lars Haack, David Krug, Justus Domschikowski, Olaf Wittenstein, Severin Rodler, Philipp Nuhn, Christof van der Horst, Claudia Schmalz, Christian Schulz, Oliver Blanck, Frank-André Siebert, Alexander Fabian

“…Therefore, our primary objective was to investigate associations of urethral dose and long-term patient-reported urinary morbidity after external beam radiotherapy and high-dose rate brachytherapy boost for prostate cancer. Materials and methods: We conducted a pre-registered (https://doi.org/10.17605/OSF.IO/A6DC3) cross-sectional study at a tertiary academic center including a consecutive sample of patients being at least two years after treatment. …”
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Clinical Evaluation of LASEK for High Myopia Correction between the Triple-A Profile and the Zyoptix Tissue Saving Profile by Min Li, Yuehui Shi, Lina Sun, Lin Liu, Chen Qu, Jun Zou

“…To compare the effects of correcting high myopia using the MEL®90 Triple-A profile LASEK at a 500 Hz pulse rate (Triple-A group) versus the Zyoptix tissue-saving ablations of Technolas 217z laser platform at 100 Hz (TS group). Methods. This retrospective study included 50 eyes in the Triple-A group and 42 eyes in the TS group with manifest refraction spherical equivalent (MRSE) of −6 diopters (D) to −10 D. …”
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Effect of Tonifying deficiency and Zhengqi porridge on immune function reconstruction in HIV/AIDS patients with Qi deficiency (补虚正气粥对艾滋病气虚型患者免疫功能重建的影响研究)... by WEI Yan (魏艳), LI shu (李树), YUAN Hongxia (袁洪霞), ZHANG Ying (张英), LIU Xiaoli (刘小丽), LIU Lingling (刘玲玲)

“…Objective To observe the effect of Tonifying deficiency and Zhengqi porridge on immune function reconstruction of HIV/AIDS patients with Qi deficiency. Methods Sixty (Human Immunodeficiency Virus/ Acquired Immunodeficiency Syndrome)HIV/AIDS patients admitted to the center for Disease Control and prevention in Huichuan District of Zunyi City were randomly divided into control group and treatment group by random number table. …”
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Application of auricular acupoint scraping therapy in postoperative patients with lower extremity fracture (耳穴推刮术在下肢骨折术后患者中的应用) by GUI Huiqiong (桂辉琼), WANG Yihua (王一华), YUAN Qingna (袁庆娜), JI Chen (冀晨), YANG Yihua (杨毅华)

“…Objective To observe the effect of auricular acupoint scraping therapy on postoperative pain and sleep quality of patients with lower extremity fracture. Methods Totally 70 cases of patients undergoing surgery for lower limb fracture were randomly divided into control group and observation group, with 35 cases in each group. …”
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Effect of prehospital physician presence on Out-of-Hospital cardiac arrest (OHCA) patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR): A secondary analysis of t... by Futoshi Nagashima, Satoshi Inoue, Tomohiro Oda, Tomohiro Hamagami, Tomoya Matsuda, Makoto Kobayashi, Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Yasuhiro Kuroda

“…This study aimed to evaluate whether the presence of prehospital physicians improves 30-day survival and favorable neurological outcomes in this population. Methods: This retrospective study analyzed data from the SAVE-J II study, a nationwide multicenter cohort of OHCA patients treated with ECPR in Japan. …”
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Time Interval for Diagnosis of Tuberculosis and Related Expenditure in Selected Health Centers in Addis Ababa, Ethiopia by Ezra Shimeles, Melaku Tilahun, Tsegaye Hailu, Fikre Enquselassie, Abraham Aseffa, Alemayehu Mekonnen, Getachew Wondimagegn

“…Therefore, the study aimed to assess the time interval between developing TB symptom until patients start anti-TB treatment and associated cost incurred by patients and families. Methods. This cross-sectional study was conducted among pulmonary TB patients who are bacteriologically confirmed, whose age is above 15 years and diagnosed at health centres in Addis Ababa. …”
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LLT1 overexpression renders allogeneic-NK resistance and facilitates the generation of enhanced universal CAR-T cells by Shuxian Zhu, Shiyu Zuo, Chuo Li, Xingjie You, Erlie Jiang, Xiaoming Feng, Yuechen Luo

“…This study tested whether the overexpression of Lectin-like transcript 1 (LLT1), an NK cell inhibitory ligand, in T cell receptor (TCR) and HLA-I/II disrupted universal CD38-targeting CAR-T cells could prevent rejection by allogeneic NK cells. Methods We generated CD38-targeting universal CAR-T cells by transducing T cells with lentiviruses encoding the CD38 CAR and LLT1 constructs. …”
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Application of medical care linkage model in the whole process management of surgery in the treatment of redundant prepuce and phimosis in children (医护联动模式在小儿门诊包皮手术管理中的应用)... by ZHANG Qing (张庆), CHEN Puxin (陈普新), TAO Yanling (陶艳玲)

“…Objective To investigate the doctor-nurse-linkage mode in the whole process of surgery in the treatment of redundant prepuce and phimosis in children. Methods Totally 120 cases of redundant prepuce and phimosis in children were randomly divided into two groups, with 60 cases in each group. …”
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Technological dental sealants: in vitro evaluation of material properties and antibiofilm potential by Witalo Pereira de Jesus, Luiza de Almeida Queiroz Ferreira, Washington Henrique Themoteo da Silva, Fernanda Vieira Belém, Ana Paula Turrioni, Cláudia Silami de Magalhães, Mila Fernandes Moreira Madeira, Ivana Márcia Alves Diniz, Marco Aurelio Benini Paschoal

“…Abstract Background Due to the launch of new self-etching and self-adhesive sealing materials combined with the release of bioactive ions in the dental market, this in vitro study aimed to compare physical values of surface roughness (RS), vickers microhardness (VM), compositional energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), microbiological tests (inhibition halo-HI and surface microbial adhesion-MAS) and mechanical microshear bond strength (MBS). Methods The following groups were analyzed: Beautisealant® self-etching sealant (Shofu)(G1), FluroShield® conventional sealant (Dentsply)(G2- Control Group), Flow Constic® self-adhesive/self-etching resin (DMG)(G3) and Beautifil Flow Plus F03® conventional resin (Shofu)(G4). …”
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Therapeutic potential of rutin in premenstrual depression: evidence from in vivo and in vitro studies by Xiangjun Wang, Xiaowen Xia, Xianliang Song, Yi Zhou, Mingyu Ma, Yashuang Ren, Xitai Chen, Zenghui Xia, Yinghui Guo, Chunhong Song

“…The study of the efficacy and mechanism of action of rutin in PMDD-depressed subtype model rats plays an important role in the discovery of new drugs for the treatment of PMDD.MethodsBinding of rutin to gamma-aminobutyric acid type A receptors (GABAA receptors) was probed using molecular docking, microscale thermophoresis, radioactive receptor ligand binding assay and cell membrane clamp experiment. …”
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Deltopectoral approach without subscapularis detachment for reverse shoulder arthroplasty. Technique and results of a safe and reproducible subscapularis-sparing approach by Adrien Jacquot, MD, MSc, Thomas Cuinet, MD, Lisa Peduzzi, MD, Patrice Wong, MD, Marc-Olivier Gauci, MD, PhD, Julien Uhring, MD

“…We present the surgical technique and results. Methods: In a retrospective study, we included our first 45 cases of reverse total shoulder arthroplasty performed with the AMS approach for a degenerative affection of the shoulder (massive rotator cuff tear, cuff tear arthropathy, primary glenohumeral arthritis, or rheumatoid arthritis), excluding traumatic and revision cases. …”
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EIF1AX mutation in thyroid tumors: a retrospective analysis of cytology, histopathology and co-mutation profiles by Noha Elsherbini, Dong Hyun Kim, Richard J. Payne, Thomas Hudson, Véronique-Isabelle Forest, Michael P. Hier, Alexandra E. Payne, Marc P. Pusztaszeri

“…We investigated the prevalence of EIF1AX mutations and co-mutations in cytologically indeterminate thyroid nodules at our institution. Methods A 5-year retrospective analysis was performed on surgically resected thyroid nodules with identified EIF1AX mutations on molecular testing with ThyroseqV3®. …”
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Molecular characterization of ST15 carbapenem-resistant Klebsiella pneumoniae isolated in a single patient by Yongjin Hu, Rong Tang, Shanshan Jin, Jiahao Guan, Xiaoxiao Meng, Zengpeijie Dan, Ruilan Wang, Hong-Yu Ou, Jian Lu

“…In this study, we analysed the clinical and molecular characteristics of drug resistance changes in KP strains isolated from a single patient, and the potential mechanisms underlying these resistance changes. Methods: Antimicrobial susceptibility test and string test were conducted to evaluate the resistant and virulent characterization of the strains. …”
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Effect of Cognitive Rehabilitation Strategies based on Eye Movement Techniques for Executive Function of Patients after Stroke by Wen HE, Yazheng JI, Xiating WEI, Hua LIN, Fan WANG, Feng XU, Chengyi LU, Qianqian MA, Hongbing WANG

“…Objective:To observe the effect of cognitive rehabilitation strategies based on eye movement techniques for executive function of patients after stroke.Methods:A total of 64 patients with executive dysfunction after stroke from the Forth Rehabilitation Hospital of Shanghai were randomly divided into the control group and the observation group according to the Excel Rand function, with 32 cases in each group. …”
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Yeast cell wall polysaccharides accelerate yet in-feed antibiotic delays intestinal development and maturation via modulating gut microbiome in chickens by Fangshen Guo, Jianing Qiao, Zeqiong Hu, Jia Huang, Ruichen Bi, Waseem Abbas, Wenrui Zhen, Yuming Guo, Zhong Wang

“…This study aimed to investigate the effects of dietary yeast cell wall polysaccharides (YCWP) addition on intestinal development and maturation of chickens and its potential action mechanism. Methods 180 one-day-old male Arbor Acres broilers were randomly assigned to three groups containing control (basal diets without any antibiotics or anticoccidial drug), bacitracin methylene disalicylate (BMD)-treated group (50 mg/kg) and YCWP-supplemented group (100 mg/kg). …”
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Evolution of burnout syndrome in Spanish healthcare professionals during and after the COVID-19 pandemic: psychosocial variables involved by Fernanda Gil-Almagro, Fernanda Gil-Almagro, Fernanda Gil-Almagro, F. Javier Carmona-Monge, Fernando J. García-Hedrera, Cecilia Peñacoba-Puente

“…The preceding literature also points to the need to consider the three elements of burnout independently, as they appear to have different evolutionary trends and possibly different buffering and amplifying variables, although these aspects have hardly been explored.MethodsThe aim of the present investigation is precisely to shed light on these latter issues. …”
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