Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

“…Therefore, our study aims to meticulously investigate genomic distinctions among multiple pulmonary nodules within individual patients. Methods We performed targeted DNA sequencing on tumor specimens and conducted bulk RNA transcriptome analysis on 53 multiple nodules originating from 26 lung cancer patients. …”
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Tratamento Diretamente Observado para a Tuberculose na Atenção Primária à Saúde: discursos e práticas by Ingrid Gabriel Grigorio, Kalyta Michaelly Silva Glória, Milena de Oliveira Simões, Katiuscia Cardoso Rodrigues, Flávia Rodrigues Pereira

“…ABSTRACT Objective: To define Directly Observed Treatment for Tuberculosis from the perspective of Primary Health Care professionals in Governador Valadares, Minas Gerais, Brazil, and to present the actions related to this treatment strategy that they implement. Method: This is a qualitative and descriptive study based on an action-research approach, conducted with Primary Health Care health professionals in the municipality of Governador Valadares, MG. …”
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Quantification of Forest Regeneration on Forest Inventory Sample Plots Using Point Clouds from Personal Laser Scanning by Sarah Witzmann, Christoph Gollob, Ralf Kraßnitzer, Tim Ritter, Andreas Tockner, Lukas Moik, Valentin Sarkleti, Tobias Ofner-Graff, Helmut Schume, Arne Nothdurft

“…The objective of this study is to develop an accurate and reliable method for estimating regeneration coverage from data obtained through personal laser scanning (PLS). …”
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Time to first antenatal care visit and its predictors among women in Kenya: Weibull gamma shared frailty model (based on the recent 2022 KDHS data) by Bizunesh Fantahun Kase, Beminate Lemma Seifu, Kusse Urmale Mare, Abdu Hailu Shibeshi, Hiwot Altaye Asebe, Kebede Gemeda, Zufan Alamrie Asmare, Yordanos Sisay Asgedom, Bezawit Melak Fente, Afework Alemu Lombebo, Tsion Mulat Tebeje

“…Therefore, this study aimed to assess and provide up-to-date information on time to first antenatal care visit and its predictors among women in Kenya, using data from the most recent 2022 Kenya Demographic and Health Survey (KDHS). Methods This community-based cross-sectional study analyzed data from 19,530 birth histories in the 2022 Kenya Demographic and Health Survey (KDHS). …”
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Global burden of subarachnoid hemorrhage among adolescents and young adults aged 15-39 years: A trend analysis study from 1990 to 2021. by Xuanchen Liu, Rui Cheng, Yingda Song, Xiaoxiong Yang, Xiaochen Niu, Chunhong Wang, Guijun Jia, Hongming Ji

“…<h4>Objective</h4>This study aims to analyze the global burden of subarachnoid hemorrhage (SAH) among adolescents and young adults (AYAs) aged 15-39 years from 1990 to 2021, highlighting spatial and temporal trends and providing insights for future public health strategies.<h4>Methods</h4>Data were collected from the Global Burden of Disease Study 2021 (GBD 2021), which includes comprehensive evaluations of health conditions and associated risk factors across 204 countries and territories. …”
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Contribution à l’étude de la mobilité de l’hallux et de la phylogénie des primates actuels by J Norbert Kuhlmann

“…Material and methods: 51 anatomical specimens of non-human primates were dissected (18 embalmed, 33 fresh). …”
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Differential diagnostic value of P wave dispersion and QT interval dispersion between psychogenic pseudosyncope and vasovagal syncope in children and adolescents by Zifeng Huang, Yi Xu, Shuo Wang, Ping Liu, Xingfang Zen, Yuwen Wang, Fang Li, Runmei Zou, Cheng Wang

“…This paper will study the differential diagnostic value of P wave dispersion (Pd) and QT interval dispersion (QTd) between PPS and VVS. Methods The 31 children with PPS and 40 children with VVS from July 2014 to November 2023 were enrolled as the study group. …”
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Differentiating Liver Metastases from Primary Liver Cancer: A Retrospective Study of Imaging and Pathological Features in Patients with Histopathological Confirmation by Laura Andreea Ghenciu, Mirela Loredana Grigoras, Luminioara Maria Rosu, Sorin Lucian Bolintineanu, Laurentiu Sima, Octavian Cretu

“…<b>Background and Objectives:</b> This study aimed to identify and analyze imaging and pathological features that differentiate liver metastases from primary liver cancer in patients with histopathological confirmation, and to evaluate the diagnostic accuracy of imaging modalities. <b>Materials and Methods:</b> This retrospective study included 137 patients who underwent liver biopsy or resection between 2016 and 2024, comprising 126 patients with liver metastases and 11 patients with primary liver cancer (hepatocellular carcinoma). …”
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Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma by Nayia Petousi, Nick P Talbot, Ian Pavord, Peter A Robbins, Nicholas M J Smith, Graham Richmond, Asma Alamoudi, Lorenzo Petralia, Haopeng Xu, Dominic Sandhu, Grant AD Ritchie

“…Here, we assessed changes in lung inhomogeneity in patients with type-2 high asthma treated with biological therapy and explored the relationship between inhomogeneity measures and conventional asthma disease markers.Methods This was an observational study of 91 severe type-2 high asthma patients recruited from a tertiary asthma clinic, of whom 67 subsequently started anti-IL5 or anti-IL5R biologics. …”
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Pre-exposure Prophylaxis Awareness and Endorsement among Adolescents and Young Adults in Tanzania: Insights from the 2022 Demographic and Health Survey by Alpha Johnson Kapola, Rahma Musoke, Glenda Marie Manayon, Hassan Fredrick Fussi, Hafidha Mhando Bakari, Haji Mbwana Ally, Swalehe Mustafa Salim, Zuhura Mbwana Ally, Lynn Moshi, Mariam Salim Mbwana, Habib Omari Ramadhani

“…Objectives: This study evaluates the prevalence of PrEP awareness and endorsement, as well as the factors associated with these outcomes, using data from the 2022 Tanzania Demographic and Health Survey. Methods: The analysis included participants aged 15–24 years. …”
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Postoperative radiotherapy improves survival in completely resected non-small cell lung cancer with pathologic N2 stage IIIA and positive lymph node count greater than one: a SEER-... by Diyang Zhu, Yuanyuan Xiao, Yuanyuan Xiao, Shancheng He, Shancheng He, Baochang Xie, Baochang Xie, Wenqi Zhao, Wenqi Zhao, Yuhui Xu

“…This study seeks to evaluate the effect of postoperative radiotherapy (PORT) on overall survival (OS) and cancer-specific survival (CSS) in patients with resected pathologic N2 (pN2) stage IIIA NSCLC.MethodsData from the Surveillance, Epidemiology, and End Results Program (SEER) 17 registry (2010–2019) were analyzed. …”
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Longitudinal exploration of cancer-related cognitive impairment in patients with newly diagnosed aggressive lymphoma: protocol for a feasibility study by Vincent Dore, Christopher C Rowe, Meinir Krishnasamy, Haryana Dhillon, Adam K Walker, Karla Gough, Priscilla Gates, Carlene Wilson, Eliza Hawkes, Yuliya Perchyonok, Janette L Vardy, Michiel de Ruiter

“…This paper describes the protocol for a study: (1) to assess the feasibility of collecting longitudinal data on cognition via self-report, neuropsychological testing, peripheral markers of inflammation and neuroimaging and (2) to explore and describe patterns of cancer-related cognitive impairment over the course of treatment and recovery in patients with newly diagnosed, aggressive lymphoma undergoing standard therapy with curative intent.Methods and analysis This is a prospective, longitudinal, feasibility study in which 30 newly diagnosed, treatment-naive patients with aggressive lymphoma will be recruited over a 12-month period. …”
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Hurdle Approach to Simulate Corn Wet Milling Inactivation of Undesirable Microorganisms: A Pilot Scale Microbial Challenge Study Using Salmonella Surrogate Enterococcus faecium by Erin Kealey, Madeline Shick, Minho Kim, Ruben Chavez, Gordon Shetley, David Stenger, Kirk A. Perreau, Allison Cooke, Cecil Barnett-Neefs, Matthew J. Stasiewicz

“…Industry-relevant conditions for CWM processes were recreated at pilot or lab scale for 3 unit operations: (1) steeping treatment in sulfur dioxide (SO2) with low (750 ppm SO2, 20 h, 43.3 °C), medium (1,500 ppm SO2, 30 h, 48.9 °C), and high (2,200 ppm SO2, 40 h, 53.3 °C) treatment conditions; (2) hydrogen peroxide (H2O2) treatment tested on bench scale with a factorial design (pH 3.5, 4.0, and 4.5), H2O2 concentrations (0.05%, 0.10%, 0.15% (w/w)), and temperatures (32, 38, and 46 °C) for 3 and 6 h; (3) flash drying treatment at 4 different temperatures (149, 177, 204, and 232 °C) with 2 different inoculation methods. E. faecium was reduced during each of these unit operations. …”
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Hubungan Antara Cache, Energy Consumption dan Runtime Performance pada Progressive Web Apps by Wakhid Kurniawan, Agung Fatwanto

“…The purpose of this study is to investigate the relationship between Cache and Runtime Performance and Energy Consumption. The research method uses a quantitative approach by conducting an empirical experimental study, which assesses 16 sites that have adopted Progressive Web Apps. …”
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Prognostic nutritional index as a predictor of cardiovascular and all-cause mortality in American adults with hypertension: results from the NHANES database by Jing Tang, Jing Tang, Long Yang, Guan-Ying Yang, Yan-Hong Li, You-Sen Zhu, Hui Li, Xiao-Ming Gao, Xiao-Ming Gao, Xiao-Ming Gao

“…This study aimed to examine the association between PNI and cardiovascular mortality and all-cause mortality in Americans with hypertension.MethodsData from this retrospective cohort study were obtained from the National Health and Nutrition Examination (NHANES) 1999–2016. …”
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Predictors of Unfavorable Outcomes in Patients with Atrial Fibrillation and Concomitant Heart Failure with Different Ejection Fractions: RIF-CHF Register One-Year Follow-Up by Igor Zhirov, Natalia Safronova, Yulia Osmolovskaya, Alina Alshevskaya, Andrey Moskalev, Sergey Tereshchenko

“…The objective of this study was to analyze how the features of the course of the diseases and management of HF + AF influence the clinical outcomes. Methods. The data of 1,003 patients from the first Russian register of patients with chronic heart failure and atrial fibrillation (RIF-CHF) were analyzed. …”
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Reasons and countermeasures of nursing disputes in the nucleic acid testing clinic (核酸检测门诊护理纠纷的原因与对策研究) by ZHAO Jialu (赵佳璐), WANG Huaxin (王华新), ZHOU Jie (周洁), TANG Ling (唐玲), MA Kexin (马可欣), ZENG Chunfeng (曾春凤)

“…Objective To investigate the factors of high incidence of nursing disputes in the nucleic acid testing clinic, and to optimize management and reduce the incidence of nursing disputes. Methods A retrospective before-after study was conducted. …”
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Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank by Ting Li, Jing Chen, Yan Zheng, Klodian Dhana, Geng Zong, Yuan Ma, Trudy Voortman, Wei Gan, Yaying Cao, Yonghua Hu, Changzheng Yuan, Jie Shen, Gaohong Zhu, Chengwu Feng

“…Background Cardiovascular risk burden is associated with dementia risk and neurodegeneration-related brain structure, while the role of genetics and incident cardiovascular disease (CVD) remains unclear.Aims To examine the association of overall cardiovascular risk burden with the risk of major dementia subtypes and volumes of related brain regions in a large sample, and to explore the role of genetics and CVD onset.Methods A prospective study among 354 654 participants free of CVD and dementia (2006–2010, mean age 56.4 years) was conducted within the UK Biobank, with brain magnetic resonance imaging (MRI) measurement available for 15 104 participants since 2014. …”
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Correlation between Glycated Hemoglobin Levels and Knowledge, Attitude, and Practice of Type 2 Diabetic Patients Attending Primary Health Care Centers in Dubai Health Authority by Hind Al Razooqi, Bashayer AlNajjar, Ebrahim AlShamsi, Kaltham Ibrahim, Wadeia Sharief, Hamda Khansaheb, Marwan Zidan

“…This study aimed to find the correlation between the KAP of type 2 diabetes and HbA1c levels in patients attending primary health care centers (PHCs) in Dubai. Methods: This cross-sectional study was conducted by a face-to-face questionnaire in patients with type 2 diabetes who visited PHCs in Dubai. …”
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Overground robotic exoskeleton vs conventional therapy in inpatient stroke rehabilitation: results from a pragmatic, multicentre implementation programme by Pui Kit Tam, Ning Tang, Nur Shafawati Binte Kamsani, Thian Yong Yap, Ita Coffey-Aladdin, Shi Min Goh, Jean Pei Pei Tan, Yook Cing Lui, Rui Ling Lee, Ramaswamy Suresh, Effie Chew

“…We analysed prospectively collected data from Improving Mobility Via Exoskeleton (IMOVE), a multicentre clinical implementation programme of ORE enrolling participants with various neurological conditions and were given options to choose between 12 sessions of ORE or conventional therapy (control). Methods This is analysis of participants under IMOVE who fulfilled the following criteria (i) primary diagnosis was stroke (ischemic, hemorrhagic; first or recurrent), (ii) onset of stroke was within 9 months and (iii) the intervention was during inpatient stay. …”
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