Association Between Triglyceride–Glucose Index and Carotid Plaque Stability in Different Glycemic Status: A Single‐Center Retrospective Study by Guijun Huo, Jin Zheng, Junjie Cao, Lili Zhang, Zhichao Yao, Yuqi Zeng, Yao Tang, Zhanao Liu, Ziyi Tan, Dayong Zhou

“…This study investigated the association between the TyG index and unstable carotid plaque. Methods A total of 12 068 participants were enrolled. …”
Get full text

Application of continuous improvement process in reducing the return-cleaning rate of lumen surgical instruments (质量持续改进活动在降低手术管腔器械清洗返洗率中的应用)... by JIANG Linghua (蒋玲华), LI Shaoping (李绍平), YAO Shixiu (姚仕秀), YANG Weizao (杨伟造)

“…Objective To investigate the effect of continuous improvement process (CIP) in reducing the return-cleaning rate of lumen surgical instruments. Methods A CIP group was set up, and theme and plan of CIP activities were identified. …”
Get full text

Effects of Replacing Inorganic Sources of Copper, Manganese, and Zinc with Different Organic Forms on Mineral Status, Immune Biomarkers, and Lameness of Lactating Cows by Manqian Cha, Xingjun Ma, Yunlong Liu, Shengyang Xu, Qiyu Diao, Yan Tu

“…(Objectives) The objectives of this study were to evaluate the effect of half-replacement of the supplementary sulfate sources of Cu, Mn, and Zn with methionine-hydroxy-analog-chelated (MHAC) mineral or amino-acid-complexed (AAC) mineral forms in diets on the mineral status, blood immune biomarkers, and lameness of lactating cows. (Methods) Sixty multiparous Holstein cows (158 ± 26 days in milk; body weight: 665 ± 52 kg; milk yield: 32 ± 7 kg/day) were randomly assigned into one of three dietary treatments (<i>n</i> = 20 per group): (1) MHAC: 50% replacement of sulfate minerals with MHAC forms. (2) AAC: 50% replacement of sulfate minerals with AAC forms. (3) S: 100% sulfate minerals (control). …”
Get full text

Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“….-32-13T>G and other GAA exon 2-skipping mutations. Methods A set of constructs expressing 5 different engineered U1 snRNAs was generated. …”
Get full text

Hubungan Indeks Massa Tubuh dengan Ketahanan Kardiorespirasi, Kekuatan dan Ketahanan Otot dan Fleksibilitas pada Mahasiswa Laki-Laki Jurusan Pendidikan Dokter Universitas Andalas A... by Haslan Muhaimin Lubis, Delmi Sulastri, Afriwardi .

“…Cardiorespiratory endurance obtained by calculating the value of bycycle ergometer test using VO2maks method astrand 6 minute cycle test, conducted measurement of height and weight, muscle strength is graded with a hand dynamometer and back strength dynamometer, muscle endurance is assessed with the bent leg sit-up, and flexibility with the sit and reach test, trunk extension, and shoulder lift. …”
Get full text

Erroneous Classification and Coding as a Limitation for Big Data Analyses: Causes and Impacts Illustrated by the Diagnosis of Clavicle Injuries by Robert Raché, Lara-Sophie Claudé, Marcus Vollmer, Lyubomir Haralambiev, Denis Gümbel, Axel Ekkernkamp, Martin Jordan, Stefan Schulz-Drost, Mustafa Sinan Bakir

“…This study aims to assess the frequency of diagnostic errors in clavicle injury classifications. <b>Methods</b>: This retrospective study analyzed patient data from two Level 1 trauma centers, covering the period from 2008 to 2019. …”
Get full text

Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

“…However, the precise role of autophagy lysosomal signaling in astrocytes that regulates tau pathology remains unclear. Methods We investigated the expression of class IIa HDAC7 in astrocytes from AD patients and PS19 mice. …”
Get full text

OBSERVATION OF THE NORMAL DEVELOPMENTAL PATTERN OF FETAL CEREBRAL SULCI BETWEEN 18 TO 32 WEEKS OF GESTATIONAL AGE BY USING ULTRASONOGRAPHY - A CORRELATIONAL STUDY BETWEEN TWO MATER... by Sujith Kumar Reddy Madithati, Sai Shankar Mankuzhy Gopalakrishnan, Santosh Chandrasekhar, Jenikar Paulraj, Archana Bala, Geeta Shankar

“…The research aims at observing normal developmental pattern of fetal cerebral sulci between 18 to 32 weeks of gestational age by using ultrasonography. Material and Methods. This is a Cross-sectional observational study, performed among 110 antenatal women investigated under the Department of Radio Diagnosis, Shri Sathya Sai medical college and research institute, Ammapettai. …”
Get full text

Planetary health education in undergraduate medical education in Germany: results from structured interviews and an online survey within the national PlanetMedEd Project by Fabio Grieco, Sandra Parisi, Anne Simmenroth, Michael Eichinger, Michael Eichinger, Janina Zirkel, Janina Zirkel, Sarah König, Jana Jünger, Jana Jünger, Eva Geck, Eva-Maria Schwienhorst-Stich

“…This study therefore aimed (a) to assess the current implementation of Planetary Health in undergraduate medical education in Germany and (b) to explore its characteristics as a foundation to develop evidence-informed recommendations for mainstreaming Planetary Health Education in medical schools in Germany.MethodsThe study comprised structured interviews followed by an online survey, both targeting all 39 medical schools in Germany. …”
Get full text

Thermal and packaging materials for enhancing the longevity and aroma integrity of fragrant rice during storage by Rajesh Chakraborty, Tuhin Suvra Roy, Jun-Ichi Sakagami

“… Due to improper storage methods, a few months after storage the grain quality has gone to deteriorate. …”
Get full text

Development of an individualized dementia risk prediction model using deep learning survival analysis incorporating genetic and environmental factors by Shiqi Yuan, Qing Liu, Xiaxuan Huang, Shanyuan Tan, Zihong Bai, Juan Yu, Fazhen Lei, Huan Le, Qingqing Ye, Xiaoxue Peng, Juying Yang, Yitong Ling, Jun Lyu

“…However, there is a lack of deep learning-based survival analysis models that integrate both genetic and clinical factors to develop and validate individualized dynamic dementia risk prediction models. Methods and results This study is based on a large prospective cohort from the UK Biobank, which includes a total of 41,484 participants with an average follow-up period of 12.6 years. …”
Get full text

Risk factors for dengue mortality: a 7-year retrospective cohort in Honduras by Dilcia Sauceda-Acosta, Sandra Paola Paz Almendares, Elsy Cárcamo, Melba Zúniga-Gutiérrez, Briana Beltrán, María Félix Rivera, Marlon Meléndez Rodríguez, Judy Enamorado

“…The aim of this study was to describe the epidemiological trends of dengue cases and dengue death cases and identify the demographic, clinical and laboratory risk factors for dengue mortality in Honduras. Methods A retrospective cohort study of suspected cases of dengue between 2016 and 2022 was conducted. …”
Get full text

Noninvasive oxygenation and ventilation strategies for viral acute respiratory failure: a comprehensive systematic review and meta-analysis by Fredy Leonardo Carreño-Hernández, Sergio Prieto, Daniela Abondando, Jairo Alejandro Gaitán, Yenny Rocío Cárdenas -Bolívar, Adriana Beltrán, Jorge Iván Alvarado-Sánchez, Joseph L. Nates

“…The primary outcome was the all-cause ICU mortality rate. Methods A systematic review was conducted following the Cochrane guidelines and PRISMA reporting guidelines. …”
Get full text

Magnitude, patterns, and factors associated with liver disease among clinically suspected clients in Eastern Ethiopia: hidden public health tragedy by Aliya Nuri, Sufian Jeilu, Yared Teklu, Kadir Abdu, Ahmed Muhye, Milkiyas Solomon Getachew, Imam Dagne, Muluken Yigezu, Sewmehon Amsalu Adugna, Vanisha S. Nambiar, Abdu Oumer

“…This study was to assess the magnitude, patterns, and factors associated with liver disease among patients visiting governmental hospitals in eastern Ethiopia. Methods A facility-based cross-sectional study was conducted among randomly selected 388 clinically suspected adults for liver disease visiting a public hospital in Dire Dawa, Ethiopia. …”
Get full text

Nisin A-producing Lactococcus cremoris formulations for pre- and post-milking teat disinfection modulate the bovine milk microbiota by Alessandra Gazzola, Camilla Ceccarani, Bianca Castiglioni, Filippo Biscarini, Stefano Morandi, Tiziana Silvetti, Renata Piccinini, Milena Brasca, Paola Cremonesi

“…Microbial communities were investigated by cultural and sequence-based methods, and analyzed through bioinformatic and statistical approaches. …”
Get full text

High perioperative lactate levels as a potential predictor for severe acute kidney injury following aortic arch surgery by Dongxu Wang, Chen Yang, Han Wang, Mengmeng Ye, Chao Xue, Weiguang Wang, Bo Yu, Kai Ren, Zhenxiao Jin, Shiqiang Yu, Shiqiang Yu, Weixun Duan

“…The aim of this study was to investigate the predictive value of perioperative lactate levels in severe postoperative AKI after TAR.MethodsA cohort analysis of 328 patients who underwent TAR with frozen elephant trunk implantation at Xijing Hospital, Xi’an, China, between September 2019 and September 2023 was conducted. …”
Get full text

3D-Printed PCL-Based Scaffolds with High Nanosized Synthetic Smectic Clay Content: Fabrication, Mechanical Properties, and Biological Evaluation for Bone Tissue Engineering by Furtado ASA, Cunha MHS, Sousa LMR, Brito GC, Verde TFCL, Filgueiras LA, Sobral-Silva LA, Santana MV, Sousa GF, Santos FEP, Mendes AN, Figueredo-Silva J, Maia Filho ALM, Marciano FR, Vasconcellos LMR, Lobo AO

“…The main challenge lies in achieving a uniform distribution of nanoceramics across low to high concentrations within the polymer matrix while preserving mechanical properties and biological performance essential for successful osseointegration.Methods: This study utilized 3D printing to fabricate PCL scaffolds enriched with nanosized synthetic smectic clay (LAP) to evaluate its effects on structural, chemical, thermal, mechanical, and degradative properties, with a focus on in vitro biological performance and non-toxicity. …”
Get full text

ApoB/ApoA-Ι is associated with major cardiovascular events and readmission risk of patients after percutaneous coronary intervention in one year by Jie Zhang, Mengyu Liu, Ju Gao, Xiaowen Tian, Yaru Song, Haibei Zhang, Peng Zhao

“…Abstract Percutaneous coronary intervention (PCI) is a practical and effective method for treating coronary heart disease (CHD). …”
Get full text

Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels by Yuliya A. Kukushkina, Irena A. Ilovayskaya

“…Aim: To identify hallmarks of clinical and biochemical parameters in patients with acromegaly and normal or increased prolactin level. Methods: We performed a single center, single sample retrospective, observational cohort uncontrolled non-interventional study in 306 patients (70 men and 236 women) with acromegaly examined from July 2021 to June 2024, 50 of them with a pituitary microadenomas and 256 with macroadenomas. …”
Get full text

Hypoxia-Elicited Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Myocardial Infarction by Promoting Angiogenesis through the miR-214/Sufu Pathway by Lianbo Shao, Yihuan Chen, Jingjing Li, Jingfan Chao, Ziying Yang, Yinglong Ding, Han Shen, Yueqiu Chen, Zhenya Shen

“…We also investigated the potential mechanisms. Method. huMSCs were preconditioned with hypoxia (1% O2 and 5% CO2 at 37°C for 48 hours), and their sEVs were isolated using the Total Exosome Isolation reagent kit. …”
Get full text