Effect of external application of Shuangbai powder combined with microwave therapy on acute joint pain of patients with gout (双柏散外敷结合微波理疗缓解痛风患者急性关节疼痛的效果观察)... by WEI Sihua (韦思华), QIN Jianghua (覃江华), WEI Changna (韦昌娜), QIN Hai (覃海)

“…Objective To investigate the effect of external application of Shuangbai powder combined with microwave therapy on acute joint pain of patients with gout. Methods Totally 160 patients with gout were randomly divided into the control group and the observation group, with 80 cases in each group. …”
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Post-training breakdown: acute effects of different training types on body hydration status and performance by Erkan Demirkan, Mehmet İsmail Tosun, Abdurrahim Kaplan, Mert Ayrancı, Damian George Cosmin, Mustafa Arıcı, Mehmet Kutlu, Veysi Aslan, Michael Favre

“…This study aimed to examine the acute effects of endurance, strength, and wrestling training sessions on hydration status and performance parameters in young wrestlers, providing insights to guide more effective hydration and recovery strategies.MethodA total of 14 experienced young wrestlers participated in a crossover design, completing endurance, strength, and wrestling training sessions on separate days. …”
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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…We precisely deliver this therapeutic agent to the dermis using microneedle (MN) patches, aiming to enhance therapeutic efficacy compared to traditional drug administration methods. After PDA-JAKi MN treatment, the symptoms of vitiligo in mice are alleviated, and the affected areas regain pigmentation. …”
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Clinical characteristics and frailty status in heart failure with preserved vs. reduced ejection fraction by Tomoyuki Hamada, Toru Kubo, Kazuya Kawai, Yoko Nakaoka, Toshikazu Yabe, Takashi Furuno, Eisuke Yamada, Hiroaki Kitaoka, Kochi YOSACOI study

“…Abstract Aims The aim of this study was to elucidate the clinical characteristics, including frailty status, of patients with heart failure with preserved ejection fraction (HFpEF) in comparison with those in patients with heart failure with reduced ejection fraction (HFrEF) in a super‐aged region of Japan. Methods and results Of the 1061 Japanese patients enrolled in the Kochi YOSACOI study, a multicentre registry, we divided 645 patients (median age of 81 years [interquartile range, 72–87 years]; women, 49.1%) into two groups, HFpEF patients (61.2%) and HFrEF patients (38.8%). …”
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Determinants of Physicochemical Composition of Palm Oil Mill Effluent - Implications on Environment and Bio-digester Treatment Design by E.B. Tambe, A.U. Okonkwo, I. E. Mbuka-Nwosu, C.O. Cookey, E. Agbe, S.C. Onwusa, I.N. Ekpe, U.F. Evuen, J. Okpoghono

“…From a randomly sampled small-scaled mill in each community, and for the lone medium and large-scaled mills, four homogenous samples of POME were collected from sampled small, medium and large-scaled mills for laboratory analysis of potential of hydrogen (pH), dissolved oxygen (DO), biochemical oxygen demand (BOD), chemical oxygen demand (COD), total carbon (TC), total solid (TS), total suspended solid (TSS), total organic carbon (TOC), total nitrogen (TN), total kjeldahl nitrogen (TKN), ammonia nitrogen (NH3-N), Manganese (Mn), Nickel (Ni), Iron (Fe), Copper (Cu), Chromium (Cr), Cadmium (Cd), Potassium (K), total phosphorus (TP), Calcium (Ca), and Magnesium (Mg) using standard methods for wastewater analysis as described in American Public Health Association. …”
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Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021 by Qi Zhang, Lan Luo, Lai-lai Yan, Lai-lai Yan, Jing Guo, Hui-jun Wu, Zi-wei Zhang, Yu-hua Zhu, Rui Qiao, Rui Qiao

“…BackgroundTo evaluate global, regional, and national trends in the burden of neonatal diseases attributable to LBW, as well as associated health inequalities, from 1990 to 2021.MethodsUsing data from the Global Burden of Disease Study (GBD2021), we analyzed deaths and DALYs due to LBW-attributable neonatal diseases. …”
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Approach to death and dying patients and its relation with death anxiety among medical interns: a multicenter cross-sectional study by Israa Sharabati, Mohamed M. M. Mustafa, Masah Ateeq, Hasan Al-jabali, Amira Ahmed Elsayed, Ahmed Hamdy Kandil, Mohamed Nabil Hamouda, Noor Alrawajfeh, Sadeel Abu Sharib, Razan A. Abumayyala, Omar Rafeek Alkhateeb, Mira Bishtawi, Juana Abu Rahmeh, Tasneem Hetta, Raghad Abuzant, Farah Al-Mubaid

“…The purpose of this study was to assess the attitude of medical interns toward death and dying patients as well as their level of death anxiety. Methods This cross-sectional study was conducted on medical interns across three countries—Egypt, Jordan, and Palestine—using an online survey created with Google Forms. …”
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Faktor-faktor yang Berhubungan dengan Tingkat Pengetahuan Wanita Usia Subur Tentang “SADARI” di Nagari Painan by Vitro Darma Yusra, Rizanda Machmud, Yenita Yenita

“…The objective of this study was to determine the factors that associated to  the level of knowledge to infertile women about BSE in Nagari Painan village on 2014 .The method of this study was analytical research using  cross -sectional study design. …”
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The appearance of scalp high‐frequency oscillations is associated with poor seizure control in pediatric epilepsy patients by Keisuke Maeda, Nami Hosoda, Himari Tsuboi, Honoka Naito, Chiaki Kudo, Junichi Fukumoto, Shiho Fujita, Naohiro Ichino, Keisuke Osakabe, Keiko Sugimoto, Shunta Yamaguchi, Naoko Ishihara

“…We compared the risk of scalp HFO appearance between pediatric patients with good and poor seizure control by treatment with ASMs. Methods A total of 72 epilepsy patients (aged 0–18 years, 39 males) with good and poor seizure control with ASMs participated in this study. …”
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Prevalence and determinants of clustering of adverse lifestyle behaviors among 35 – 75 years old residents at high cardiovascular disease risk in Hebei province: an analysis of dat... by Yuejing QIAO, Yuhuan LIU, Lijuan TANG, Dongsheng JIANG, Xiaoli LIU, Ze CUI

“…ObjectiveTo investigate the prevalence and influencing factors of clustering of adverse lifestyle behaviors in populations at high risk of cardiovascular disease (CVD) in Hebei province, thus providing a reference for the prevention and control of CVD in the local population. MethodsInformation on 29 721 residents aged 35 – 75 years who were considered at high risk of CVD was collected from the datasets of the CVD Early Detection and Comprehensive Intervention Project, which was conducted in 11 sites in Hebei province from 2018 to 2021. …”
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Tackling the unyielding: testing two novel approaches against NDM-producing Enterobacterales and Pseudomonas aeruginosa isolates collected in India by Yamuna Devi Bakthavatchalam, Bijayini Behera, Anand Shah, Purva Mathur, Raja Ray, Bashir Ahmed Fomda, Kamini Walia, Balaji Veeraraghavan

“…Minimum inhibitory concentrations of antibiotics against multicentric NDM-producing Escherichia coli (n = 117), Klebsiella pneumoniae (n = 103), and P. aeruginosa (n = 72) were determined by the reference broth microdilution method. Among E. coli, 111 isolates were NDM-alone, and six were NDM + OXA-48-like producers. …”
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Factors associated with thermal injury of abdominal skin in focused ultrasound ablation of uterine fibroids by Tang Chendian, Huang Guohua, Zhibiao Wang, Liu Fang, Shuang Luo, Xiaofang Liu, Qiuling Shi

“…Objective To investigate the factors which may cause thermal injury of abdominal skin in patients with uterine fibroids (UFs) who underwent ultrasound-guided focused ultrasound ablation surgery (FUAS).Method A total of 123 patients were enrolled in the injury group. …”
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Impact of intermediate-dose tertiary prophylaxis on quality of life and psychological aspects of adult patients with severe/moderate hemophilia A by Hua Gao, Jia Liu, Shiqiu Zhou, Jing Gao, Jing Tan, Rong Chen

“…This research aims to explore the impact of intermediate-dose tertiary prophylaxis with recombinant human FVIII (rhFVIII) on quality of life, anxiety and depression in such individuals transitioned from on-demand treatment.Methods This retrospective analysis collected data from July 2019 to July 2022. …”
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Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database by Yuwei Liu, Yuwei Liu, Xu Zhao, Xu Zhao, Xinrui Wang, Xinrui Wang, Qiang Zhou, Qiang Zhou

“…This study assessed ADRs associated with anti-fibrotic agents as reported in the World Health Organization (WHO) VigiAccess database and compared the adverse reaction characteristics of these agents for optimizing therapeutic strategies.MethodsA detailed search was conducted on ClinicalTrial.gov to identify phase 3 or 4 clinical trials involving hepatic anti-fibrotic agents. …”
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Online patients questions regarding reverse total shoulder arthroplasty pertain to timeline of recovery, specific activities, and limitations by Kyle K. Obana, MD, Dane R.G. Lind, BA, Andrew J. Luzzi, MD, Michaela J. O’Connor, MD, Matthew R. LeVasseur, MD, William N. Levine, MD

“…Hypotheses: (1) Questions will pertain to surgical indications, timeline of recovery, and postoperative restrictions; (2) the quality and transparency of online information is largely heterogenous. Methods: Three rTSA searches were entered into the Google Web Search. …”
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Clinical Efficacy of Muscle Energy Technology Combined with Conventional Rehabilitation Therapy on Patients with Chronic Non-Specific Neck Pain by ZHENG Kun, YANG Haolun, JIA Chengsen, ZHANG Liming

“…ObjectiveTo observe the effects of muscle energy technology (MET) combined with conventional rehabilitation trerapy on patients with chronic non-specific neck pain (CNSNP).MethodsA total of 54 patients with CNSNP in the outpatient department of rehabilitation medical center of West China Hospital, Sichuan University from May 2022 to March 2023 were randomly divided into control group and observation group, with 27 cases in each group. …”
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Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers by Mei Zhang, Veronique Roche, Victor Sandoval, Claire Wolford, Zachary Senders, Julian Anthony Kim, Susan Pereira Ribeiro, Alex Yicheng Huang, Rafick-Pierre Sekaly, Joshua Lyons

“…This has created a major challenge in understanding how CD11b converts the differences in the receptor-ligand binding into subsequent signaling responses and using this information for therapeutic development.Methods This study aimed to investigate the antitumor effect of a carbohydrate ligand, named BG34-200, which modulates the CD11b+ cells. …”
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eHealth literacy in the general population: a cross-sectional study in China by Chao Sun, Eline Meijer, Niels H. Chavannes, Huohuo Dai, Xiao Li, Yue Wang, Liangqiuhe Wu, Qing Zhang, Marise J. Kasteleyn

“…This study aims to explore eHL and its associated factors within the general population of China, encompassing sociodemographic characteristics, CLD knowledge, digital access, eHealth use and attitudes towards eHealth. Method Data were collected from November 2023 to January 2024 via online and hard-copy questionnaires among the general population in China. …”
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The effects of growth hormone on the outcomes of in vitro fertilization and embryo transfer in age-grouped patients with decreased ovarian reserve: a prospective cohort study by Jiexiu Chen, Xumei Kong, Zonghui Luan, Yu Qiu, Yu Qiu, Shiqi Chen, Jesse Li−Ling, Yan Gong

“…This study aims to explore the outcome of IVF-ET among differently aged patients with DOR treated with GH.MethodsA total of 846 patients with DOR undergoing IVF-ET from May 2018 to June 2023 at the Reproductive Medicine Center of Sichuan Provincial Women’s and Children’s Hospital were prospectively enrolled. …”
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Meta Analysis on Rehabilitation Effect of Proprioception Training on Ankle Sprainof Athletes by Yuxiao CHEN, Jiaojiao LIU, Changsong Yi, Mengguang CHAI, Qing WANG, Lei JIANG

“…Objective:To explore the effects of proprioception training on the incidence of athletes' ankle sprains, dynamic neuromuscular control, postural stability and joint position perception.Methods:Data were searched from the databases of PubMed, Cochrane Library, EMbase, China National Knowledge Infrastructure(CNKI), Wanfang Database(Wangfang Data), Chinese Journal Full-text Database(VIP), China Biomedical Literature Database(CBMdisc).Athletes were included in the randomized controlled trials(RCTs)who were treated with proprioception training to improve the function of athlete's ankle joint.The retrieval time for each database was from the establishment of the database to December 31, 2019, and the references of related documents were traced.Two researchers independently searchered the literature, extracted data, and evaluated the quality of the literature.RevMan5.3 software was used to analyze the data.According to the systematic review manual provided by the Cochrane Collaboration Network, the continuous variables use mean difference(<italic>MD</italic>)and 95%confidence interval(<italic>CI</italic>)as indicators, and binary variables use risk ratio(RR)and 95%<italic>CI</italic> as indicators.The statistical heterogeneity was judged comprehensively by chi-square test(χ²test)and the Heterogeneity test(<italic>I</italic>²test).If <italic>P</italic>≥0.1 and <italic>I</italic>²≤50%, a fixed effects model would be used.In contrast, if <italic>P</italic>&lt;0.1 or <italic>I</italic>²&gt;50%, a random effects model would be used.Results:A total of 11 RCTs and 1 776 athletes were included.The results of Meta analysis showed that compared with the control group, the incidence of ankle sprains in the experimental group was significantly reduced after proprioceptive training[<italic>RR</italic>=0.61, 95%<italic>CI</italic>(0.41, 0.90), <italic>P</italic>=0.01]; compared with the control group, the posterolateral and posterior medical maximum extension distances of the experimental group increased significantly after proprioception training[<italic>MD</italic>=4.44, 95%<italic>CI</italic>(3.66, 5.23), <italic>P</italic>&lt;0.00 001;<italic>MD</italic>=4.21, 95%<italic>CI</italic>(3.18, 5.24), <italic>P</italic>&lt;0.00 001]and the difference was statistically significant;but there was no significant difference in the improvement effect of the anterior maximum extension distance, and the difference was not statistically significant(<italic>P</italic>&gt;0.05).The postural sway of the affected ankle joint in the experimental group was significantly lower than that in the control group;the athletes in the experimental group had better position perception ability in the ankle joint plantar flexion, dorsiflexion, middle and lateral directions than the control group.Conclusion:Proprioceptive training can effectively reduce the incidence of athletes' ankle sprains, improve dynamic neuromuscular control, improve postural stability, and enhance ankle joint position perception, which is worthy of clinical application.However, the absolute effect is not yet clear, so large samples and high-quality randomized controlled trials are still needed to further verify the efficacy of proprioception training, so as to provide more reliable evidence-based evidence for clinical rehabilitation.…”
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