MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

“…Therefore, we hypothesized that MT2A could promote angiogenesis in chronically ischemic brains by neutralizing excessive copper ions during copper overload (CPO). Methods We first collected dura matter (DM) samples from CICD patients and examined the expression of cuproptosis-related genes (DLAT, FDX1, and SDHB) to confirm the inhibitory effect of CPO on angiogenesis. …”
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Effects of the Early Start Denver Model on emotional dysregulation and behavior problems in children with Autism spectrum disorder by Wan-Xia Liu, Ling Shan, Chun-Li Li, Yu-Mo Liu, Yang Xue, Yu-Ling OuYang, Fei-Yong Jia

“…This study aimed to explore the effect of the ESDM on addressing emotional dysregulation and behavior problems in children with ASD in China, as well as its correlation with core symptoms of ASD. Methods A total of 319 children aged 1.5 to 5 years were included in this study and received treatment based on the ESDM intervention program Baseline assessment (T0) was conducted before intervention, including Children Behavior Checklist (CBCL), Autism Behavior Checklist (ABC) and Childhood Autism Rating Scale (CARS). …”
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Analytical Accuracy of a Continuous Glucose Monitor in Adult Diabetic KetoacidosisTake-Home Points by Nathan L. Haas, MD, Lynn Ang, MD, Nazanene H. Esfandiari, MD, Ahsan M. Khan, MBBS, James A. Cranford, PhD, Ashley Cohen, MD, Jordan Sell, MD, Mostafa Abdel-Hamid, MD, Kevin E. Romanchik, BSN, RN, Frederick K. Korley, MD, PhD

“…Research Question: What is the clinical and analytical accuracy of CGM in adults with DKA? Study Design and Methods: This was a prospective observational study at a single academic medical center emergency department. …”
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The prevalence of cancer in patients with multiple sclerosis (MS) who received rituximab: a systematic review and meta-analysis by O. Mirmosayyeb, V. Shaygannejad, N. Ebrahimi, H. Ghoshouni, M. Ghajarzadeh

“…Objective: To estimate the pooled prevalence of cancer in patients with multiple sclerosis (MS) cases who were under treatment with rituximab. Methods: We searched PubMed, Scopus, EMBASE, Web of Science, and google scholar along with gray literature up to April 2021.The search strategy included the MeSH and text words as ((“CD20 Antibody” AND Rituximab) OR “Rituximab CD20 Antibody” OR Mabthera OR “IDEC-C2B8 Antibody” OR “IDEC C2B8 Antibody” OR IDEC-C2B8 OR “IDEC C2B8” OR GP2013 OR Rituxan OR rituximab) AND ((Sclerosis AND multiple) OR (sclerosis AND disseminated) OR ''disseminated sclerosis'' OR ''multiple sclerosis'' OR ''acute fulminating''). …”
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Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes by T. Magcwebeba, L. McEvoy, S. Hayward, T. Tait, J.L Quanson, L. Kelbe, WCA Gelderblom, M. Lilly, A.C Swart, P. Swart

“…Purpose: The study aimed to evaluate the anti-inflammatory and anti-carcinogenic properties of S. tuberculatiformis extract and Compound A, particularly their effects on UVB-induced inflammation, cell growth parameters, and oxidative status in HaCaT cells. Methods: The biological activity of S. tuberculatiformis extract and Compound A was assessed using a cytochrome P450 assay. …”
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Overall Survival of Patients with Metastatic Renal Cell Carcinoma Following the Introduction of Targeted and Immunotherapies: A Norwegian Retrospective, Real-World Registry Data St... by Puco K, Notland CS, Szulkin R, Jonasson C, Beisland C, Johannesen TB, Solli O, Oldenburg J, Heinrich D

“…The results may provide additional information on the benefits of tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) in clinical practice.Patients and Methods: We performed a longitudinal, retrospective, non-interventional cohort study using data from four national registries. …”
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Comparison of Ultrasound Energy Delivered to the Anterior Segment Across Different Phacoemulsification Surgical Platforms by Nelson TK, Ricks RG, Cardenas IA, Whitaker T, Jensen JL, Olson RJ, Pettey JH

“…Tanner K Nelson,1,2 Reiker G Ricks,1,2 Ivan A Cardenas,1,2 Tyler Whitaker,1,2 Jenna L Jensen,1,2 Randall J Olson,1 Jeff H Pettey1 1Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, University of Utah, Salt Lake City, Utah, USA; 2University of Utah School of Medicine, Salt Lake City, Utah, USACorrespondence: Jeff H Pettey, John A Moran Eye Center, University of Utah, 65 Mario Capecchi Drive, Salt Lake City, UT, 84132, USA, Tel +1 801 581 2352, Fax +1 801 581 3357, Email jeff.pettey@hsc.utah.eduPurpose: The aim of this study was to use calorimetry to understand the difference in energy transferred by three phacoemulsification surgical platforms to the eye.Patients and Methods: A phacoemulsification tip was lowered into a double-walled calorimeter filled with distilled water. …”
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Efficacy and Safety Outcomes of Intravitreal Dexamethasone Implant Therapy for the Treatment of Adult Coats’ Disease by Qingshan Chen, Saying Liang, Xizhen Wang, Chenli Hu, Jieting She, Zi Li

“…To evaluate the efficacy and safety outcomes of dexamethasone intravitreal implant in patients with Stage 3A Coats’ disease. Methods. A consecutive case series of adult Coats’ disease managed with or without intravitreal dexamethasone implant (Ozurdex®, Allergan Inc., Irvine, California, USA) injection was retrospectively evaluated. …”
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Effect of moxibustion combined with cupping therapy in the treatment of lumbar disc herniation of Qi-stagnation and Blood-stasis type (艾灸联合拔罐治疗血瘀气滞型腰椎间盘突出症临床疗效观察)... by ZHANG Xi (张西), GENG Qingwen (耿庆文), ZHOU Dengfang (周登芳), TANG Ling (唐玲), DUAN Peihang (段培航)

“…Objective To investigate the effect of moxibustion combined with cupping therapy in the treatment of lumbar disc herniation of Qi-stagnation and Blood-stasis type. Methods Totally 60 patients with lumbar disc herniation of Qi-stagnation and Blood-stasis type were randomly divided into the observation group and control group, with 30 cases in each group. …”
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Effectiveness of Video Teletherapy in Treating Obsessive-Compulsive Disorder in Children and Adolescents With Exposure and Response Prevention: Retrospective Longitudinal Observati... by Jamie D Feusner, Nicholas R Farrell, Mia Nunez, Nicholas Lume, Catherine W MacDonald, Patrick B McGrath, Larry Trusky, Stephen Smith, Andreas Rhode

“…ObjectiveThis study reports on the real-world effectiveness of teletherapy ERP for OCD in the largest sample (N=2173) of child and adolescent patients to date. MethodsChildren and adolescents with OCD were treated with live, face-to-face video teletherapy sessions, with parent or caregiver involvement, using ERP. …”
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Research on equity analysis and forecasting of nursing human resource allocation in Jiangxi Province, China by Yunyu Du, Zhiqin Xie, Zhen Yang, Wanyin Xiong, Li Zhou, Min Zhang, Suhua Zeng, Min Wang

“…Objectives: This study aimed to assess the equity of nursing human resource allocation in Jiangxi Province, China, and forecast future trends in the next five years. Methods: We used the related data from the China Statistical Yearbook, China Health Statistics Yearbook, and Jiangxi Statistical Yearbook (2003–2022). …”
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Inducing salt stress tolerance in bitter gourd (Momordica chanrantia) through seed treatment with chitosan by Ahsan Ali, Fiaz Hussain Ferdosi, Mubeen Sarwar, Sumreen Anjum, Zain Mushtaq, Mehwish Liaquat, Muhammad Taqqi Abbas, Moazzam Anees, Muhammad Rizwan Tariq, M. Irfan Ashraf, Abdulrahman Alasmari, Md Sabir Ahmed Mondol, Gholamreza Abdi

“…Thus, the impact of soil salinization on the economics of bitter gourd yield deserves scientific inquiry. MethodsThe present study was designed to evaluate the various morphological attributes (mean germination time, germination index, final emergence percentage, measurements of root length, measurement of shoot length, measurement of plant dry biomass, and measurement of plant fresh biomass), physiological attributes (leaf chlorophyll content and electrolyte leakage), biochemical attributes (proline contents, antioxidant enzymes, superoxide dismutase, catalase Q9 , and peroxidase), leaf water relations (leaf osmotic potential, leaf water potential, leaf turgor potential, and leaf relative water content), and ion concentrations (Na+, K+, Ca +, and Cl-) that can be used for the evaluation of salt stress tolerance potential in bitter gourd. …”
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The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…The study delves into novel hematological inflammatory markers, such as systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and prognostic nutritional index (PNI), to explore their potential applications in early diagnosis of GC.Methods: From October 2020 and August 2024, 1339 GC patients admitted to our hospital were enrolled in this study. …”
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Analisis Perpindahan Wisatawan dan Preferensi Desrinasi Wisata Favorit Berdasarkan Geotag Instagram (Studi Kasus pada Destinasi Wisata Bandung Raya) by Herry Irawan, Eva Nurhazizah, Joe Nathan C.G. Panjaitan

“…Identification of tourist movement pattern is done by using the association rules method. The findings of this study are tourist destinations with shopping center tourist attractions have higher support and confidence values than other tourist attractions. …”
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Electroporation and GFP-labelled transplantation of testicular cells in Nile tilapia by Epro Barades, , Alimuddin, Agus Oman Sudrajat

“…This study was performed to obtain an alternative method of cell labelling using electroporation. Testicular cells were taken from 4-months old Nile tilapia as a model. …”
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Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max) by Jinyu Zhang, Liying Zou, Li Wang, Dongchao Zhang, Ao Shen, Yongqi Lei, Maoni Chao, Xinjuan Xu, Zhiwei Xue, Zhongwen Huang

“…Based on the classification method used for Arabidopsis Sec14 members, GmSec14s can be categorized into three classes: GmPITP1 to GmPITP37, GmSFH1 to GmSFH25, and GmPATL1 to GmPATL15. …”
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Implementasi Kebijakan Retribusi Parkir Badan Jalan di Kota Pekanbaru by Ema Fitri Lubis, Rio Sundari, Rosmayani Rosmayani, Zilfi Purnama Rahmi

“…This research aims to analyze what factors hinder the implementation of the on-street parking levy policy in Pekanbaru City. The method used in this research is descriptive qualitative, collecting data by means of interviews, observation and documentation. …”
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Soil phosphorus mobilization as affected by long-term organic fertilization in a tropical Regosol by Kalline De Almeida Alves Carneiro, Tancredo Augusto Feitosa De Souza, Gislaine Dos Santos Nascimento, Vânia Da Silva Fraga, Bruno de Oliveira Dias

“…This study aimed to evaluate the PM in a tropical Regosol by using soil columns (10 cm depth) during steady saturated water flow and PM was correlated with Fe and Al oxides. Method: Soil samples were collected in four sites characterized as smallholder farming systems that shared the same land uses and soil type with each other. …”
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Effects of Chemical Fertilizer Reduction Combined with Straw and Organic Fertilizer Application on Soil Acidification Mitigation and Erosion Control by SHEN Mengxue, HAO Rui, LIU Xinwei, WEI Wanhao, CAO Yunfei, SHU Hujia, HAO Zongyu, WANG Huyu, WANG Ling, SHI Zhihua

“…[Objective] To demonstrate that appropriate application of straw and organic fertilizer can effectively improve soil quality, have a positive effect on soil acidification mitigation and erosion control. [Method] Acidified red soil was used as the research object and a comparative analysis was performed for the effects of conventional fertilization (CK), chemical fertilizer reduction (30%), straw returning (6 000 kg/hm2, FSM0), and the combination of chemical fertilizer reduction (30%) coupled with straw returning (6 000 kg/hm2) and different gradients of organic fertilizers (1 500, 3 000, 4 500 and 6 000 kg/hm2) (FSM1, FSM2, FSM3, and FSM4) on soil properties at different stages of rapeseed growth and rapeseed yield. …”
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Impact of ultrasound-guided percutaneous flexor retinaculum fenestration on outcome of hydrostatic dissection of median nerve in patient with carpal tunnel syndrome by Ahmed M. Zidan, Hytham Mohamed Nafady, Mohamed Abdelrahman Alkenawy, Mohammad Abol Wafa Ahmad, Ahmed Mohamed Eldeeb, Mohamed Talaat Mohamed, Mahmoud Mohamed Aboumandour Fouda, Hasan A. Soltan, Nehal Elsayed Shabaan, Ahmed B. M. Mehany, Yasser Fouad Ghoraba

“…Aim To assess the effect of ultrasound-guided percutaneous flexor retinaculum fenestration on the outcome of hydrostatic dissection of the median nerve in cases with CTS. Methods This randomized clinical research included a total of 54 individuals with CTS separated into two groups; group (A) included patients with hydrostatic dissection with adjuvant fenestration of transverse carpal ligament (n = 27), while group (B) involved patients with hydrostatic dissection alone (n = 27). …”
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