Comparison of Proximal Tibiofibular Joint Detachment with Tibial-Sided Osteotomy for Fibular Untethering in Lateral Closing-Wedge High Tibial Osteotomy: A Cadaveric Study by Ryu Kyoung Cho, Keun Young Choi, Dai-Soon Kwak, Man Soo Kim, Yong In

“…The aim of this study was to compare the degree of completion and safety of PTFJD versus tibial-sided osteotomy (TSO); this latter procedure is our novel technique for fibular untethering during LCWHTO. <i>Materials and Methods:</i> Sixteen fresh frozen cadaver knees from eight cadavers were included in the study. …”
Get full text

Assessment of relative energy deficiency in sport and malnutrition prevalence in female endurance runners by energy availability questionnaire, bioelectrical impedance analysis and... by Samantha Sharp, Roni Mashiach-Fransis, Nicola Keay, Adrian Slee

“…This study investigated the relationship between REDs screening, BIA assessment of malnutrition and ovulatory status in female endurance runners using an Energy Availability Questionnaire, Bioelectrical Impedance Assessment (BIA) and female reproductive sex hormone levels. Methods: 70 female runners from London, UK running clubs participated in this study. …”
Get full text

Sedentarismo e inactividad física según sexo, edad y nivel socioeconómico en el País Vasco. Estudio transversal by Marta Ijalba Martínez, Antonio Moreno Llamas, Unai Martín Roncero

“…Abstract: Objective: To describe the prevalence of sedentarism and physical inactivity according to sex, age, and socioeconomic level in the Basque Country. Method: A cross-sectional study was conducted based on the 2018 Basque Autonomous Community Health Survey (n = 7814 adults). …”
Get full text

Audit Tata Kelola Academic Information System Menggunakan Framework Cobit 2019 by Satriya Dwi Putra, Herman Herman, Anton Yudhana

“…The expected output is a recommendation to maximize the system development process using a gradual method, namely observation, data collection, data validation, and identification of maturity level data. …”
Get full text

Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up by Fabrizio Giansanti, Cristina Nicolosi, Giuseppe Ruben Barbera, Giulio Vicini, Flavia Lucarelli, Edoardo Traniello Gradassi, Vittoria Murro, Gianni Virgili, Daniela Bacherini

“…Background: To investigate functional and anatomical outcomes after pars plana vitrectomy (PPV) for lamellar macular hole (LMH) with a long-term follow-up. Methods: An interventional study on 14 patients (16 eyes) with LMH was conducted. …”
Get full text

Prognostic significance of p27 in colorectal cancer: a meta-analysis and bioinformatics analysis by Jing Zou, Dong Wang, Gaoping Yin, Kexiang Lu, Kaibin Chang, He Li

“…BackgroundIn the past, numerous investigations have delved into the influence of p27 (p27kip) on the prognosis and clinicopathological characteristics of colorectal cancer (CRC), yielding conclusions that are not universally statistically significant, thus rendering the discourse rather contentious.MethodsWe collected available articles published before August 2024 and extracted data to analyze the association between the expression of p27 and the prognosis and clinicopathological features of CRC. …”
Get full text

The PerioGene North study reveals that periodontal inflammation and advanced jawbone loss in periodontitis associate with serum gingipain antibodies but not with systemic autoimmun... by Elin Kindstedt, Elin Kindstedt, Charlotte de Vries, Magnus Wänman, Barbara Aleksandra Potempa, Jan Potempa, Jan Potempa, Susanne Lindquist, Anders Esberg, Karin Lundberg, Pernilla Lundberg

“…In the present study, we set out to further explore the relationship between anti-Rgp IgG, ACPA and periodontitis, including clinical periodontal parameters, in the large and well-characterized PerioGene North case-control study.MethodsWe measured serum levels of anti-Rgp and ACPA IgG by enzyme-linked immunosorbent assay (ELISA), in 478 patients with periodontitis and 509 periodontally healthy controls within PerioGene North. …”
Get full text

An observational, multigenerational platform for health systems and population health interventions to minimise intergenerational transmission of non-communicable diseases in India... by Vaman Khadilkar, Tarun Reddy Katapally, Jasmin Bhawra, Neha Kajale, Rubina Mandlik, Vivek Patwardhan, Demi Miriam, Dipali Ladkat, Chidvilas More, Ketan Gondhalekar, Anuradha Vaman Khadilkar

“…Taking a life course perspective, this multigenerational cohort study aims to investigate behavioural, socioecological, and socioeconomic determinants of growth and NCD risk, as well as healthcare access and utilisation among preadolescents and their parents.Methods and analysis The study is being implemented by the Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI) using a prospective, multigenerational cohort design to investigate NCD risk over 15 years. …”
Get full text

Real-world clinical and economic impacts of delayed rotator cuff repair surgery in Japan: analysis of a large claims database by Hiroyuki Sugaya, MD, Yuki Otaka, BS, Yuichi Shiotsuki, MS, MPH, Akie Seno, BSc, MBA

“…This study aimed to understand the impact of early vs. delayed RCR on real-world healthcare costs and resource use (HCRU) in Japan. Methods: This study utilized JMDC health insurance claims data from January 2012 to February 2021. …”
Get full text

Evaluation and Management of Patients with Seizures in the Emergency Department: A One-Year Analysis by K. Puteikis, K. Zdanytė, R. Mameniškienė

“…The study aims to determine the prevalences of causes of TLoC in the ED, analyse the characteristics of patients with seizures or established epilepsy in particular and estimate the level of evaluation and management they receive in respect to available international guidelines. Materials and methods. The data was cross-sectional and was retrieved from the local database of Vilnius University Hospital Santaros Klinikos from January 1st to December 31st, 2016. …”
Get full text

Assessment of Visual Quality in Eyes with Forme Fruste Keratoconus and Mild and Moderate Keratoconus Based on Optical Quality Analysis System II Parameters by Zhonghao Ren, Liyan Xu, Qi Fan, Kaili Yang, Shengwei Ren, Dongqing Zhao

“…The study aimed to evaluate the visual quality of forme fruste keratoconus (FFK) and mild and moderate keratoconus by using an optical quality analysis system II (OQAS-II) and to explore the correlation between optical quality parameters and the disease progression. Methods. Twenty-one normal eyes, twenty-one FFK eyes, twenty-one mild keratoconus eyes, and twenty-one moderate keratoconus eyes were included in this prospective study. …”
Get full text

Sistem Identifikasi Penyakit Paru Obstruktif Kronik (PPOK) Berdasarkan Suara Paru-Paru Menggunakan Jaringan Saraf Tiruan Berbasis Raspberry Pi by Lindhu Parang Kusuma, Barlian Henryranu Prasetio, Eko Setiawan

“…One way that is commonly used by doctors to diagnose lung conditions is to use a stethoscope. This method is commonly referred to by the name of auscultation. …”
Get full text

Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activating the... by Jiaochen Luan, Mengchi Yu, Qi Gu, Xuan Zhou, Yunqiang Shao, Tong Chen, Jiayi Zhang, Zheng Zhu, Ninghong Song, Jie Yang

“…BackgroundErectile dysfunction (ED) is a prevalent male sexual disorder, commonly associated with hypertension, though the underlying mechanisms remain poorly understood.ObjectiveThis study aims to explore the role of Fatty acid synthase (Fasn) in hypertension-induced ED and evaluate the therapeutic potential of the Fasn inhibitor C75.Materials and methodsErectile function was assessed by determining the intracavernous pressure/mean arterial pressure (ICP/MAP) ratio, followed by the collection of cavernous tissue for transcriptomic and non-targeted metabolomic analyses. …”
Get full text

Molecular uncovering of important helminth species in wild ruminants in the Czech Republic by Lucie Škorpíková, Jaroslav Vadlejch, Jana Ilgová, Radim Plhal, Jakub Drimaj, Ondřej Mikulka, Jan Magdálek, Martin Kašný, Nikol Reslová

“…Traditional coprological methods are often limited by their labor-intensive nature and potential for erroneous identification due to morphological similarities among parasite species. …”
Get full text

Cost-effectiveness of decentralising acute malnutrition treatment with a standard or simplified treatment protocol: an economic evaluation in the region of Gao, Mali by Bernardette Cichon, Noemí López-Ejeda, Salimata Samake, Cornelia Aton, Abdias Ogobara Dougnon, Mahamadou N’tji Samake, Aliou Bagayoko, Magloire Bunkembo, Alexandra Rutishauser-Perera, Pilar Charle-Cuellar

“…The objective of this study was to determine cost per child treated as well as the cost-effectiveness of the hybrid model of treatment delivery (where treatment is provided at both health facilities and CHW sites) using either a standard protocol (Intervention 1) or simplified protocol (Intervention 2) compared to standard treatment at health facilities only (Control) in the conflict affected region of Gao in Northern Mali. Methods This economic evaluation was part of a three-arm cluster randomized controlled trial which enrolled 2038 children with moderate and severe acute malnutrition. …”
Get full text

Resistance exercise training improves disuse-induced skeletal muscle atrophy in humans: a meta-analysis of randomized controlled trials by Xian Guo, Yanbing Zhou, Xinxin Li, Jinhao Mu

“…Abstract Background This meta-analysis aimed to determine whether resistance exercise training (RET) can attenuate the loss of muscle volume and function in anti-gravitational muscles, especially quadriceps and calf muscles, during immobilization/disuse conditions. Methods A comprehensive literature search was conducted to identify randomized controlled trials comparing RET vs. no exercise during immobilization/disuse. …”
Get full text

Use of Indocyanine Green (ICG) to Assess Myocardial Perfusion and Territorial Distribution of Vein Grafts Implanted on Coronary Arteries in an Ex-vivo Porcine Model. A Potential Ad... by Cristiano Spadaccio, Antonio Nenna, Diletta Corrado, Carter Glenn, Antonio Panza, Russell Vester, Grzegorz Laskawski, David Rose, Louis Louis

“…This study aimed to evaluate the feasibility of using ICG to assess graft patency and territorial distribution of myocardial reperfusion during CABG. Methods: Porcine arrested hearts (n = 18) were used to evaluate territorial distribution of native coronary arteries and of a coronary bypass constructed with porcine saphenous vein graft (SVG) using ICG. …”
Get full text

Prevalence and associated factors of multidimensional poverty among rural households in East Gojjam zone, Northern Ethiopia: a community-based cross-sectional study by Amare Wubishet Ayele, Yeshiwas Ewinetu, Asefa Delesho, Yirsie Alemayehu, Hayimro Edemealem

“…Therefore, this study tried to assess the prevalence and identify the associated factors of MP among rural households in selected woredas of East Gojjam Zone, Northern Ethiopia. Methods A community-based cross-sectional study was conducted in the fall of 2020 in randomly selected woredas of East Gojjam zone, involving 770 rural households. …”
Get full text

Upregulated SAE1 Drives Tumorigenesis and Is Associated with Poor Clinical Outcomes in Breast Cancer by Hong Liu, Jing Wang, Yunhai Li, Feng Luo, Lei Xing

“…Through bioinformatics analysis and in vitro experiments, the biological function and possibly associated signal pathways of SAE1 in BC were further analyzed. Methods. Bioinformatics analysis was applied to analyze SAE1 expression in BC and normal breast tissues, its relationship with clinicopathologic characteristics and prognosis in BC patients, and data from the Cancer Genome Atlas database and Gene Expression Omnibus dataset. …”
Get full text

Comparative Study on the Efficacy and Safety of Tumor Resection in Vitrectomy for Retinal Vasoproliferative Tumors by Bin Zheng, Yan Chen, Lifeng Chen, Huan Chen, Jingwei Zheng, Feng Chen, Zongming Song, Lin Fu, Xuting Hu, Jiandong Pan, Hengli Lian, Lijun Shen, Qiuming Li

“…To investigate the efficacy and safety of combined vitrectomy with tumor resection in the treatment of retinal vasoproliferative tumors (RVPT). Methods. Retrospective study. RVPT patients who underwent vitreous surgery at the Eye Hospital of Wenzhou Medical University from January 2011 to July 2017 were included. …”
Get full text