Çocuklarda Dental Anksiyete: Başarılı Dental Tedavinin Önündeki Engel by Aysun Avşar, Büşra Mutlu

“…In order to progress and complete the steps of dental treatment, anxiety can be managed non-pharmacologically with pharmacological methods such as sedation and general anesthesia, aromatherapy, music therapy, visual and auditory distraction and hypnosis by watching videos during treatment. …”
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HKA angle exceeding 5 degrees is strongly associated with lateral patellar translation beyond 2 mm: surgical recommendations for avoiding adverse effects on the patellofemoral join... by Zheng Jiang, Nan Zhen, Yanjie Mao, Axiang He, Han Guo, Weiming Lin, Diwen Tang, Yang Qu, Tsung-Yuan Tsai, Wanjun Liu

“…We aimed to quantify the changes in the kinematics and cartilage conditions of the PFJ during stair climbing before and after OWHTO. Methods We recruited 15 patients who underwent unilateral OWHTO. …”
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Individual and Combined Effects of Diabetes and Glaucoma on Total Macular Thickness and Ganglion Cell Complex Thickness: A Cross-sectional Analysis by Dhruven Shah, Rita Dhamankar, Vijay Shetty, Suhas S Haldipurkar, Prakash Chipade, Shabnam Tanwar, Prachi Sankhe, Devendra Venkatramani, Paresh Mhatre, Maninder Singh Setia

“…We conducted the study to compare individual and combined effects of diabetes and glaucoma on macular thickness and ganglion cell complex thickness. Methods: The present study is a cross-sectional analysis of 172 eyes of 114 individuals. …”
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Utilisation des Anti-Inflammatoires Non Stéroïdiens chez les personnes âgées en rhumatologie au CHR-Tsévié (Togo) by VES Koffi-Tessio, E Fianyo, ML Diallo, S Oniankitan, A Adjolou, KC Tagbor, KA Nouvedji, M Ngakui, A Tsowou, C Deghela, K Kakpovi, P Houzou, O Oniankitan, M Mijiyawa

“… Objectif : déterminer la place des Anti-Inflammatoires Non Stéroïdiens (AINS) chez les rhumatisants âgés au Centre Hospitalier Régional Tsévié.   Patients et méthodes : Une étude rétrospective à visée descriptive et analytique a été menée de décembre 2022 à octobre 2023 portant sur des patients âgés (≥60 ans) ayant été traités par des anti-inflammatoires non stéroïdiens. …”
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Clinical and morphological basis of two-step surgery for cataract and glaucoma by E.A. Ivachev, M.G. Fedorova

“…</p> <p> <b>Patients and Methods: </b>this study enrolled 87 patients with cataract and glaucoma. 18 patients (20.7%) were diagnosed with moderate glaucoma and 69 patients (79.3%) were diagnosed with advanced glaucoma. …”
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Pengembangan Media Pembelajaran Berbasis Website pada Mata Pelajaran Dasar Desain Grafis Menggunakan Model Pengembangan Four-D (Studi pada SMK Negeri 1 Rembang) by Azka Azkiyah, Satrio Hadi Wijoyo, faizatul amalia

“…The researcher developed a web-based learning media with Four-D development method (define, design, develop, and disseminate). …”
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CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis by Hong-Fei Yao, Jieqiong Ge, Jiahao Chen, Xiaoyan Tang, Chunjing Li, Xiao Hu, Abousalam Abdoulkader Ahmed, Yunlong Pu, Guihua Zhou, Tongyi Zhang, Zhiwei Cai, Chongyi Jiang

“…This study aimed to confirm the existence of disulfidptosis in pancreatic ductal adenocarcinoma (PDAC) and elucidate the role of Cancer Susceptibility 8 (CASC8) in this process. Methods The existence of disulfidptosis in PDAC was assessed using flow cytometry and F-actin staining. …”
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A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome by Ying Zhang, Yu Chen, Fa-Ying Liu, Jing-Wen Fu, Xian-Xian Liu, Jun Tan, Ou-Ping Huang, Yang Zou

“…Previous genome-wide association study (GWAS) showed that Wing-less-related integration site (Wnt) signaling is the most affected pathway among PCOS-related risk genes, and genetic mutations in the Wnt/β-catenin signaling may lead to abnormal development of PCOS.Objective To explore the possibility of axis inhibitor-2 (AXIN2) variants in Chinese women with PCOS and assess their pathogenicities.Methods A total of 365 Chinese women with PCOS and 905 women without PCOS as control were recruited from Jiangxi Provincial Maternal and Child Health Hospital, All of the 11 exons and flanking regions of the AXIN2 gene were amplified by polymerase chain reaction (PCR), the potential variants were analyzed by Sanger sequencing. …”
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Betulinic Acid Inhibits the Metastasis of Colon Cancer Cells through Regulating TGF-β/Smad Signaling Pathway by Xiaoying LIN, Aling SHEN, Meizhu WU, Ying CHENG, Xiaoping CHEN, Huixin LIU, Liya LIU, Zhiqing SHEN, Xiangyan WU, Nanhui XU, Jianfeng CHU, Youqin CHEN, Jun PENG

“…Objective:To explore the effect of betulinic acid (BA) on the growth and metastasis of colon cancer cell line HCT116 and the underlying possible mechanism.Methods:HCT116 cells were cultured with McCoy's 5A medium containing 10%fetal bovine serum and 1%penicillin/streptomycin mixed solution in a 37℃,5%CO₂incubator. …”
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Electrochemotherapy with bleomycin, oxaliplatin, or cisplatin in mouse tumor models, from tumor ablation to in situ vaccination by Katja Uršič Valentinuzzi, Katja Uršič Valentinuzzi, Urška Kamenšek, Urška Kamenšek, Simona Kranjc Brezar, Chloe Heranney, Chloe Heranney, Tilen Komel, Tilen Komel, Simon Buček, Simon Buček, Maja Čemažar, Maja Čemažar, Gregor Serša, Gregor Serša

“…By evaluating ECT’s potential for in situ vaccination, our goal was to pave the way for future advancements for its combination with emerging (immuno)therapies, leading to enhanced responses and outcomes.MethodsWe employed two mouse tumor models, the immunologically cold B16F10 melanoma and 4T1 mammary carcinoma, to explore both local and systemic (i.e., abscopal) antitumor effects following equieffective intratumoral ECT with BLM, OXA, and CDDP. …”
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Use of Go-Beyond as a Self-Directed Internet-Based Program Supporting Veterans’ Transition to Civilian Life: Preliminary Usability Study by Karolina Katarzyna Alichniewicz, Sarah Hampton, Madeline Romaniuk, Darcy Bennett, Camila Guindalini

“…ObjectiveThe study aims to identify the reach, adoption, and engagement with the program and to generate future recommendations to enhance its overall impact. MethodsThis study exclusively used data that were automatically and routinely collected from the start of the Go-Beyond program’s launch on May 24, 2021, until May 7, 2023. …”
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Quantification of regional net CO₂ flux errors in the Orbiting Carbon Observatory-2 (OCO-2) v10 model intercomparison project (MIP) ensemble using airborne measurements by J. Yun, J. Liu, J. Liu, B. Byrne, B. Weir, B. Weir, L. E. Ott, K. McKain, B. C. Baier, L. V. Gatti, S. C. Biraud

“…This study proposes a method for quantifying the errors in regional net surface–atmosphere CO<span class="inline-formula">₂</span> flux estimates from models taken from the Orbiting Carbon Observatory-2 (OCO-2) v10 MIP by using independent airborne CO<span class="inline-formula">₂</span> measurements for the period 2015–2017. …”
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Phytochemical and Bioactivity Evaluation of Bee Pollen and Androecia of <i>Castanea</i>, <i>Salix</i>, and <i>Quercus</i> Species by Nisa Beril Sen, Irena Vovk, Hasan Kırmızıbekmez, Etil Guzelmeric

“…(Türkiye) and androecia of <i>Castanea sativa</i>, <i>Salix alba</i>, and <i>Quercus pubescens</i> (apetalous trees) were evaluated for the first time by new high-performance thin-layer chromatography (HPTLC) and ultra-performance liquid chromatography (UPLC) methods using marker compounds. <i>N</i>¹,<i>N</i>⁵,<i>N</i>¹⁰-tricaffeoylspermidine was isolated, and its structure was elucidated by nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS). …”
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Multimodal magnetic resonance imaging studies on non-motor symptoms of Parkinson's disease by Weimin Qi, Xiaoyan Niu, Xiuping Zhan, Yazhou Ren, Jianhang He, Jianxia Li, Xiaolin Hou, Haining Li

“…Additionally, it evaluates the relationship between MRI findings and non-motor symptoms associated with PD. Methods: ASL, QSM, and 3DT1WI scans were performed on 48 PD patients and 46 healthy controls (HC). …”
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Advanced approach to primary microsurgical debridement of extensive scleral lacerations involving simultaneous vitrectomy and chorioretinal wound closure by S.S. Shamkin, S.N. Subbotina, A.B. Stepanyants, D.V. Salov

“…</p> <p> <b>Patients and Methods:</b> 14 patients (14 eyes) diagnosed with extensive penetrating scleral/corneoscleral laceration and polymorphic intraocular lesions associated with grade 4–5 visual impairment were enrolled. …”
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Observed climate trends and farmers’ adaptation strategies in Dendi District, West Shewa Zone, Ethiopia by Busha Getachew, Gonfa Kewessa, Worku Hailu, Gezahegn Girma

“…To enhance resilience, it is crucial to provide reliable climate information, offer training on climate-smart agriculture, ensure access to updated climate data, and promote improved irrigation methods.…”
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Cardiovascular events observed among patients in the etrasimod clinical programme: an integrated safety analysis of patients with moderately to severely active ulcerative colitis by Xiang Guo, Peter M Irving, Laurent Peyrin-Biroulet, Séverine Vermeire, Joseph Wu, Irene Modesto, David T Rubin, Marla C Dubinsky, Andres J Yarur, Miguel Regueiro, Martina Goetsch, Krisztina Lazin, Guibao Gu, Aoibhinn McDonnell, Jesse Green, Alexis B Dalam

“…We report cardiovascular treatment-emergent adverse events (TEAEs) associated with S1P receptor modulators and other cardiovascular events in the etrasimod UC clinical programme.Methods Patients were analysed in the Placebo-controlled UC cohort and All UC cohort. …”
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Mid-term outcome and quality of life after Bentall procedure: single-center experience by I. O. Stetsyuk, L. R. Stetsiuk, B. M. Todurov, I. Yu. Mokryk, V. I. Zaviiskyi, I. P. Nechai, V. B. Demyanchuk, O. V. Zelenchuk

“… The aim – to evaluate the mid-term results and quality of life of patients who underwent Bentall procedure. Materials and methods. The research included 55 patients who underwent planned surgical treatment at the Heart Institute of Ministry of Health of Ukraine from 2015 to 2023. …”
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Call to Action: Lead Pharmacy into the Next Decade by Kerry K Fierke, Gardner Lepp, Bridget McGugan, Marta Brooks, Gregory Zumach

“…In keeping with the mission of INNOVATIONS in pharmacy (Iip), we invite you to share creative and dynamic scholarly leadership work. Methods The traditional written manuscript is an author-centric form of scholarly output; the format, process, expediency, and familiarity of written manuscripts benefit authors, but may not be as easily consumed as more user-centric forms of information. …”
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The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis by Zhihui Xu, Cong Liu, Peng Wang, Xing Wang, Yuzhang Li

“…ABSTRACT Background Systematic Review of The effects of exercise on inhibitory function interventions for patients with major depressive disorder. Methods We searched PubMed, Web of Science, EMbase, The Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and China Science and Technology Journal Database (CQVIP) for randomized controlled trials (RCTs) investigating the impact of exercise on inhibitory function in MDD patients, from database inception to July 2024. …”
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