Altered immune surveillance of B and T cells in patients with persistent residual lung abnormalities 12 months after severe COVID-19 by Julio Flores-Gonzalez, Ivette Buendia-Roldan, Fernanda Téllez-Quijada, Carlos Peña-Bates, Lucero A. Ramón-Luing, Armando Castorena-Maldonado, Ramcés Falfán-Valencia, Gloria Pérez-Rubio, Moisés Selman, Leslie Chavez-Galan, Leslie Chávez-Galán

“…However, the link between immune dysregulation and the development of residual lung abnormalities remains unclear. Methods 109 patients discharged with residual lung abnormalities after a critical COVID-19 were followed for 12 months and divided as full recovery patients (FRG, n = 88) and persistent lung abnormalities (PLAG, n = 21). …”
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Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma by Weiwei Chen, Chutian Wu, Yuting Li, Tonghua Wang, Miaoling Huang, Min Wang, Linjing Long, Yanfang Chen, Shufen Feng, Xuyou Liu, Shaohui Tang

“…Here, we investigated the involvement of miR-483-5p in IGF2 and H19 overexpression regulation and its role in HCC. Methods Firstly, the effect of miR-483-5p on the expression of IGF2 and H19, and the binding of miR-483-5p to IGF2/H19 enhancer were evaluated in HCC cells. …”
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Diagnostic and Predictive Values of Inflammatory Factors in Pathology and Survival of Patients Undergoing Total Cystectomy by Xingxing Tang, Yudong Cao, Jia Liu, Shuo Wang, Yong Yang, Peng Du

“…We conducted this study to evaluate whether inflammatory factors (IFs) have a diagnostic value for pathology and a predictive value for survival and recurrence in bladder cancer patients undergoing total cystectomy. Methods. The patients who were diagnosed with bladder cancer and underwent total cystectomy in our center from 2014 to 2020 were enrolled. …”
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Exosomes Derived from Apelin-Pretreated Mesenchymal Stem Cells Ameliorate Sepsis-Induced Myocardial Dysfunction by Alleviating Cardiomyocyte Pyroptosis via Delivery of miR-34a-5p by Li T, Zhao Y, Cao Z, Shen Y, Chen J, Huang X, Shao Z, Zeng Y, Chen Q, Yan X, Li X, Zhang Y, Hu B

“…This study aimed to determine whether EXOs sourced from Apelin-pretreated MSCs (Apelin-MSC-EXOs) would have potent cardioprotective effects against SMD and elucidate the underlying mechanisms.Methods: MSC-EXOs and Apelin-MSC-EXOs were isolated and identified. …”
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A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults by Zi-yue Liu, Sha Liu, Xue Yao, Chun-yang Wang, Yunhao Song, Yan-ming Bi, Jin-Xiu Wang, Yang Li, Ta-la Shi, Wei Mi, Caiyun Chen, Zhi-Yong Hu

“…ObjectiveThis study aims to investigate the potential association between serum 25(OH)D levels and the risk of hyperlipidemia in adults through a prospective cohort study conducted in Zhejiang Province.MethodsBaseline surveys and follow-up studies were conducted to collect and analyze follow-up data over a three-year period. …”
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miR-26a-5p Attenuates Oxidative Stress and Inflammation in Diabetic Retinopathy through the USP14/NF-κB Signaling Pathway by Jie Bian, Weizhong Ge, Zhengmei Jiang

“…Nevertheless, the specific functions of miR-26a-5p in DR are still unclear. Methods. Primary cultured mouse retinal Müller cells in exposure to high glucose (HG) were used to establish an in vitro DR model. …”
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Appetite Suppression and Antiobesity Effect of a Botanical Composition Composed of Morus alba, Yerba mate, and Magnolia officinalis by Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Tae-Woo Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia

“…Here we describe a standardized blend composed of extracts from three medicinal plants: Morus alba, Yerba mate, and Magnolia officinalis for appetite suppression and metabolic disorders management. Method. Extracts were standardized to yield a composition designated as UP601. …”
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Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study by Min Zhou, Min Zhou, Peng-Fei He, Peng-Fei He, Keren Zhang, Li-Juan Deng, Ning Wang, Gang Wang, Guang-Yao Yang, Shang Ju

“…This study aimed to examine the association between peripheral arterial disease (PAD) and OBS.Methods and materialsData from the National Health and Nutrition Examination Survey (NHANES, 1999–2004) were analyzed for participants with ankle-brachial index (ABI) measurements. …”
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Presence of microplastics contamination in table salt and estimated exposure in humans by D.A. Syamsu, D. Deswati, S. Syafrizayanti, A. Putra, Y. Suteja

“…This study aims to determine the abundance and characteristics of microplastics as contaminants in salt and assess the human exposure to microplastics in Indonesia.METHODS: A total of 21 samples of salt products were taken from various brands available in Padang City and Jambi City, Indonesia for analysis. …”
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The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: a systematic review and meta‐analysis by Qingling Zeng, Yuhui Yang, Limin Zhang, Jiangyu Yan, Jian Wang, Jingmin Nie, Qingmei Wang, Yu Luo, Gaoming Li

“…Herein, we aimed to evaluate changes in the prevalence of syphilis among people living with HIV (PLHIV) in China. Methods We conducted this systematic review and meta‐analysis by searching the PubMed, Embase, Web of Science, China Biomedical Literature, China National Knowledge Infrastructure, Wanfang and CQVIP databases from inception to 1 June 2024 to obtain relevant articles. …”
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Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study by Fataneh Esmaeili, Keyvan Karimi, Samaneh Akbarpour, Mohammadreza Naderian, Shirin Djalalinia, Ozra Tabatabaei-Malazy, Ali Golestani, Nazila Rezaei

“…This study targeted the association between uncontrolled HTN—defined according to the JNC8 guidelines— and different obesity patterns (general and abdominal) among adult hypertensive individuals. Methods Data for the present investigation were obtained from the 2021 STEPwise Approach to NCD Risk Factor Surveillance (STEPS) national survey in Iran. …”
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EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B by Yuyang Zhang, Mingqin Su, Yiming Chen, Li Cui, Wei Xia, Renfang Xu, Dong Xue, Xiansheng Zhang, Xingliang Feng

“…Consequently, understanding how tumours adapt to CIN is critical for identifying novel therapeutic targets. Methods Bioinformatic analyses were conducted to identify genes overexpressed in PCa tissues using The Cancer Genome Atlas (TCGA) and GEO datasets. …”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester-A primary cohort study with a scoping review. by Laura Ormesher, Jessica Catchpole, Linda Peacock, Heather Pitt, Anastasia Fabian-Hunt, Dexter Hayes, Claudia Popp, Jason M Carson, Raoul van Loon, Lynne Warrander, Karli Büchling, Alexander E P Heazell

“…This study aimed to determine the effect maternal prone position on maternal haemodynamics and fetal heart rate, compared with left lateral position.<h4>Methods</h4>Twenty-one women >28 weeks' gestation underwent non-invasive CO monitoring (Cheetah) every 5 minutes and continuous fetal heart rate monitoring (MONICA) in left lateral (20 minutes), prone (30 minutes), followed by left lateral (20 minutes). …”
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Comparative analysis of dominant gut microbiota in Inflammatory Bowel Disease patients and healthy individuals: A case-control study by Alireza Ahmadi, Ebrahim Kouhsari, Shabnam Razavi, Nima Mohamadzadeh, Sima Besharat, Mohammad Ali Vakili, Taghi Amiriani

“…Objective: This study aimed to investigate alterations in the gut microbiota composition of adult IBD patients compared to healthy controls. Methods: This case-control study investigated the relationship between faecal microbiota composition and IBD in adults. …”
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Time-varying intensity of ventilatory inefficiency and mortality in patients with acute respiratory distress syndrome by Lianlian Jiang, Hui Chen, Wei Chang, Qin Sun, Xueyan Yuan, Zongsheng Wu, Jianfeng Xie, Ling Liu, Yi Yang

“…This study aims to investigate the relationship between 28-day mortality in ARDS patients and their longitudinal exposure to ventilatory inefficiency, as reflected by serial measurements of PaCO2 and VR. Methods We conducted a secondary analysis of four randomized controlled trials (FACTT, ALTA, EDEN, and SAILS) from the ARDS Network. …”
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Ancaman dan Faktor-Faktor yang Mendorong Swedia Bergabung dengan NATO pada Tahun 2024 by Aji Irvan Saputra, Indrawati Indrawati

“…The factors behind Sweden's decision to join NATO are analyzed using qualitative research methods and through the lens of Threat Perception concept. …”
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Short-term effects of combined environmental factors on respiratory disease mortality in Qingdao city: A time-series investigation. by Xin Zhang, Zijian Xi, Min Yang, Xiuqin Zhang, Ruikai Wu, Shuang Li, Lu Pan, Yuan Fang, Peng Lv, Yan Ma, Haiping Duan, Bingling Wang, Kunzheng Lv

“…The purpose of this study was to investigate the impact of intricate environmental factors, encompassing both meteorological conditions and atmospheric pollutants, on respiratory disease (RD) mortality in Qingdao, a representative coastal city in China.<h4>Methods</h4>The RD mortality cases were collected from the Chronic Disease Surveillance Monitoring System in Qingdao during Jan 1st, 2014 and Dec 31st, 2020. …”
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Prevalence of pulmonary tuberculosis and associated factors among adults living with HIV/AIDS in Ethiopia, systematic review and meta-analysis by Amlaku Nigusie Yirsaw, Berihun Agegn Mengistie, Eyob Getachew, Gebrehiwot Berie Mekonnen, Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Gemeda Wakgari Kitil, Wubet Tazeb Wondie, Gebeyehu Lakew

“…The rise of multidrug-resistant TB further complicates diagnosis and management, highlighting the urgent need for intensified efforts to combat this dual epidemic. Methods Studies searched through the search engine of Cochrane Library, PubMed, Web of Science, Google Scholar. …”
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Design, synthesis, structural characterization, in vitro anticancer activity, and in silico studies of some new hydroxylated and fluorinated-substituted hydrazone derivatives by Reşit Çakmak, Eyüp Başaran, Ömer Erdoğan, Suraj N. Mali, Semiha Köprü, Haya Yasin, Shailesh S. Gurav, Giray Topal

“…In this study, novel hydroxylated and fluorinated-substituted hydrazone derivatives bearing an aromatic nitro moiety (2a-d and 3a-d) were designed as potential anticancer drug candidates, synthesized for the first time, and evaluated for their anticancer activity against chondrosarcoma (SW1353), a common primary malignant cartilage-forming tumor, neuroblastoma (SH-SY5Y), a type of brain cancer, and healthy (L929) cell lines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method for 24 h. The chemical structures of the target molecules were confirmed by FT-IR, 1D NMR (1H- and 13C- NMR, and APT), 2D NMR (COSY, HETCOR, and HMBC), and elemental analysis. …”
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The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…This study aimed to evaluate the effects of Naturagen® 4 Joint product containing type I, II, and III collagen on pain, quality of life, and physical functions in patients with meniscopathy. Methods This randomized, double-blind, placebo-controlled clinical study included 32 patients (collagen = 17 and placebo = 15) with meniscopathy. …”
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