Immunoregulatory Effects of Subcutaneous Immunotherapy on Lymphocyte Subgroups and Cytokines in Children with Asthma by Yu-ting He, Ying Zhou, Qi Shao, Cong Gan, Meng Chen, Yu-ling Bao, Hai-yan Gu, Shu-lan Zhang, Yubao Cui, Man Tian

“…Here, we investigated the effects of SCIT on cytokine production and peripheral blood levels of lymphocyte subtypes in children with mite-induced moderate and severe allergic asthma. Methods. The study included 60 kids with mite-induced allergic asthma from 5 to 10 years old. …”
Get full text

Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase by Anthony Huffman, Mehul Gautam, Arya Gandhi, Priscilla Du, Lauren Austin, Kallan Roan, Jie Zheng, Yongqun He, Yongqun He

“…To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines and identify enriched patterns from these viral vaccines. MethodsWe systematically collected experimentally verified viral vaccines from the literature, manually annotated, and stored the information in the VIOLIN vaccine database. …”
Get full text

Determinants of healthcare utilization under the Indonesian national health insurance system – a cross-sectional study by Qinglu Cheng, Rifqi Abdul Fattah, Dwidjo Susilo, Aryana Satrya, Manon Haemmerli, Soewarta Kosen, Danty Novitasari, Gemala Chairunnisa Puteri, Eviati Adawiyah, Andrew Hayen, Anne Mills, Viroj Tangcharoensathien, Stephen Jan, Hasbullah Thabrany, Augustine Asante, Virginia Wiseman

“…This study aims to identify factors affecting healthcare utilization in Indonesia. Methods This study analysed cross-sectional survey data collected by the “Equity and Health Care Financing in Indonesia” (ENHANCE) Study. …”
Get full text

Preoperative MRI radiomic analysis for predicting local tumor progression in colorectal liver metastases before microwave ablation by Angelo Della Corte, Martina Mori, Francesca Calabrese, Diego Palumbo, Francesca Ratti, Gabriele Palazzo, Alessandro Pellegrini, Domenico Santangelo, Monica Ronzoni, Emiliano Spezi, Antonella Del Vecchio, Claudio Fiorino, Luca Aldrighetti, Francesco De Cobelli

“…This study assesses the capability of MRI-derived radiomic features (RFs) to predict local tumor progression-free survival (LTPFS) in patients with CLMs treated with microwave ablation (MWA).Methods All CLM patients with pre-operative Gadoxetic acid-MRI treated with MWA in a single institution between September 2015 and February 2022 were evaluated. …”
Get full text

Effect of Bian-stone ironing and rubbing combined with Traditional Chinese Medicine penetration and auricular acupont pressing therapy in relieving the bloating and gastric pain of... by XUE Li (薛丽), WANG Guifang (王贵芳)

“…Objective To investigate the effect of Bian-stone ironing and rubbing combined with Traditional Chinese Medicine penetration and auricular acupont pressing therapy in relieving the bloating and gastric pain of patients with chronic gastritis. Methods Totally 60 patients with chronic gastritis were randomly divided into the observation group and control group, with 30 cases in each group. …”
Get full text

Immunogenetics of longevity and its association with human endogenous retrovirus K by Lisa M. James, Lisa M. James, Lisa M. James, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos, Apostolos P. Georgopoulos

“…Here we tested the hypothesis that certain HLA alleles may promote longevity by enhanced ability to counter virus antigens that may otherwise contribute to morbidity and mortality.MethodsWe utilized high-resolution genotyping to characterize HLA and apolipoprotein E in a large sample (N = 986) of participants (469 men, 517 women) ranging in age from 24 to 90+ years old (mean age: 58.10 years) and identified 244 HLA alleles that occurred in the sample. …”
Get full text

Evaluation of a content-based image retrieval system for radiologists in high-resolution CT of interstitial lung diseases by Benjamin Böttcher, Marly van Assen, Roberto Fari, Philipp L. von Knebel Doeberitz, Eun Young Kim, Eugene A. Berkowitz, Felix G. Meinel, Carlo N. De Cecco

“…Abstract Background This retrospective study aims to evaluate the impact of a content-based image retrieval (CBIR) application on diagnostic accuracy and confidence in interstitial lung disease (ILD) assessment using high-resolution computed tomography CT (HRCT). Methods Twenty-eight patients with verified pattern-based ILD diagnoses were split into two equal datasets (1 and 2). …”
Get full text

Sex-based differences in the long-term fate of hippocampal neurons born after a traumatic brain injury by Hannah C. Downing, Hannah C. Downing, Ashley B. Glover, Jessica E. Gebhardt, Jessica E. Gebhardt, Katherine L. Thompson, Kathryn E. Saatman, Kathryn E. Saatman, Kathryn E. Saatman

“…The goal of this study was to examine sex differences in hippocampal neurogenesis in response to a moderate controlled cortical impact brain injury.MethodsIn-vivo labeling of NPCs and tracking of their morphological development into a granule cell was achieved using an inducible Cre recombinase driven by the Ascl1 promoter in a CAG-floxStopTom reporter mouse. …”
Get full text

Hubungan Usia dan Paritas dengan Kejadian Preeklampsia Berat di Rumah Sakit Achmad Mochtar Bukittinggi Tahun 2012 - 2013 by Siqbal Karta Asmana, Syahredi Syahredi, Noza Hilbertina

“…This research used the analytical method with cross sectional study. Analysis of this research used ratio prevalence and chi-square test with degree of confidence 95%. …”
Get full text

Healthcare provision for displaced people in transit: Analyses of routinely collected data from INTERSOS clinics at the Ukrainian border with Moldova and Poland by Saleh Aljadeeah, Seyed-Moeen Hosseinalipour, Nataliia Khanyk, Eszter Szocs, Aliki Traianou, Ana Tomas, Chrysanthi Tatsi, Elżbieta Czapka, Alessandro Verona, Tessa van Boekholt, Ion Chesov, Apostolos Veizis

“…This study aims to address this gap by analyzing data from INTERSOS clinics at the Moldovan and Polish borders with Ukraine to identify the common health conditions prompting people to seek healthcare services during transit. Methods: From 6th March to 31st May 2022, this cross-sectional study observed migrants and refugees receiving INTERSOS services at two mobile clinics in Moldova, and a facility in Poland. …”
Get full text

Structure of mycoses of the skin and its appendices in HIV-infected patients by V.D. Moskaliuk, I.I. Kravchuk, Yu.O. Randiuk, I.V. Balaniuk

“…Accordingly, dermatomycosis was detected in only 97 people (29%) who were adherent to ART. The relative risk method confirms the assessment of the effect of ART on the frequency of combined forms of mycosis – RR=0.608, which indicates the obvious rarity of the event (mycosis of the skin and its appendages), compared to the group that did not receive ART. …”
Get full text

Smoking relapse reasons among current smokers with previous cessation experience in Shanghai: A cross-sectional study by Ruiping Wang*, Lingzi Shenfan*, Yu Song*, Qingliang Wang*, Rui Zhang, Le Kuai, Bin Li

“…This study aims to ascertain the differences between quitters with short and long abstinence time and to explore relapse reasons among smokers with cessation experience in Shanghai. Methods From January to December 2022, 1745 current smokers were recruited in Minhang, Jiading, Qingpu and Songjiang districts of Shanghai. …”
Get full text

Association of Serum Ferritin Levels With Obstructive Sleep Apnea in Overweight/Obese US Populations: A Population-Based Study From the NHANES by Zhang Y, Zhou P, Xu C, Su H, Li R, Sun L, Yang Y

“…Yang Zhang,1,* Pinglang Zhou,2,* Chuan Xu,3,* Hua Su,1 Rendong Li,1 Longhua Sun,2 Yihan Yang1 1Jiangxi Provincial Key Laboratory of Respiratory Diseases, Jiangxi Institute of Respiratory Diseases, The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 3Department of Thoracic Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yihan Yang, Jiangxi Provincial Key Laboratory of Respiratory Diseases, Jiangxi Institute of Respiratory Diseases, The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China, Email yangyihan@email.ncu.edu.cn Longhua Sun, The Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China, Email ndyfy05715@ncu.edu.cnObjective: To investigate the relationship between serum ferritin levels and OSA in overweight/obese individuals and assess the association between ferritin levels and all-cause mortality in overweight/obese female OSA patients.Methods: Cross-sectional (n = 4,809) and prospective (n = 832) data from overweight/obese adults from the 2005– 2008, and 2015-March 2020 NHANES cycles were analyzed. …”
Get full text

Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…This study offers a genomic analysis of C. difficile, focusing on sequence types (STs), global distribution, antibiotic resistance genes, and virulence factors in its chromosomal and plasmid DNA.MethodsA total of 19,711 C. difficile genomes were retrieved from GenBank. …”
Get full text

Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera by Thomas E. Hickey, Uma Mudunuri, Heidi A. Hempel, Troy J. Kemp, Nancy V. Roche, Keyur Talsania, Brian A. Sellers, James M. Cherry, Ligia A. Pinto

“…In this proof-of-concept study, sera from male and female vaccine recipients were evaluated for proteomic and immunologic responses 1-month and 6-months following homologous third vaccination.MethodsAn aptamer-based (7,289 marker) proteomic assay coupled with traditional serology was leveraged to generate a comprehensive evaluation of systemic responsiveness in 64 and 68 healthy recipients of mRNA-1273 and BNT162b2 vaccines, respectively.ResultsSera from female recipients of mRNA-1273 showed upregulated indicators of inflammatory and immunological responses at 1-month post-third vaccination, and sera from female recipients of BNT162b2 demonstrated upregulated negative regulators of RNA sensors at 1-month. …”
Get full text

Comparisons of open surgical repair, thoracic endovascular aortic repair, and optimal medical therapy for acute and subacute type B aortic dissection: a systematic review and meta-... by Jianping Liu, Xiaohong Chen, Juan Xia, Long Tang, Yongheng Zhang, Lin Cao, Yong Zheng

“…We aim to compare the treatments in patients with acute and subacute TBAD using a meta-analytic approach. Methods A systematic search was conducted across databases including PubMed, EmBase, and the Cochrane Library for relevant studies published from their inception up to September 2024. …”
Get full text

Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer by Xiang Pan, Kailai Chen, Wei Gao, Meiqi Xu, Fanlong Meng, Mengyuan Wu, Zi Qi Wang, Yun Qi Li, Wanhai Xu, Manjie Zhang, Yakun Luo

“…However, the functional effects and regulatory mechanisms of circRNAs in metastatic CRPC (mCRPC) remain largely unknown. Methods The expression of circBNC2 in prostate cancer (PCa), CRPC and neuroendocrine prostate cancer (NEPC) tissues was analyzed through bioinformatics analysis. …”
Get full text

Analisis Perubahan Luas Lahan Hijau Di Kota Bogor Dengan Citra Landsat 8 Menggunakan Normalized Difference Vegetation Index by Asep Denih, Irma Anggraeni, Runanto

“…The process of classifying NDVI values for vegetation and non-vegetation classes is carried out using the threshold method. Based on the research process that has been carried out for the area of vegetation in Bogor City from 2015 - 2020, it has increased by 4,46 Km2 with a land change rate of 14.4%. …”
Get full text

Advancements in Hyaluronic Acid Effect in Alveolar Ridge Preservation: A Narrative Review by Paul Andrei Nistor, Andreea Cândea, Iulia Cristina Micu, Andrada Soancă, Carmen Silvia Caloian, Alina Bârdea, Alexandra Roman

“…Additionally, it evaluates HYA’s impact—alone or in combination with other products—on hard and soft tissue dimensional changes, early wound healing, and implant success rates. <b>Methods</b>: A comprehensive electronic literature search was conducted, and studies meeting the inclusion criteria were critically evaluated. …”
Get full text

Maternal age-related declines in live birth rate following single euploid embryo transfer: a retrospective cohort study by Wei Jiang, Zichen Zheng, Nan Yan, Shuang Yao, Qijun Xie, Danyu Ni, Shanren Cao, Chun Zhao, Xiufeng Ling

“…Abstract Purpose To assess whether maternal age influences the pregnancy outcomes after single frozen euploid embryo transfer. Methods This retrospective analysis was conducted on 1037 cycles of single euploid embryo transfer performed at Nanjing Women and Children’s Healthcare Hospital between January 2016 and April 2023. …”
Get full text