Effect of Traditional Chinese Medicine directional drug penetration therapy combined with elastic bandage compression dressing on relief of ecthyma syndromes (中医定向透药联合弹力绷带加压包扎对臁疮中医... by GONG Wenjing (龚文静), LYU Lili (吕丽丽)

“…Objective To analyze the effect of Traditional Chinese Medicine(TCM) directional drug penetration therapy combined with elastic bandage compression dressing on relief of TCM syndrome in patients with ecthyma. Methods A total of 80 hospitalized patients with ecthyma were divided into two groups according their hospital admission sequence. …”
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The Association Between Medication Adherence, Internalized Stigma and Social Support Among Outpatients with Major Depressive Disorder in a Malaysian Hospital: A Cross-Sectional Stu... by Halim R, Kaur M, Syed Mokhtar SS, Chemi N, Sajatovic M, Tan YK, Siau CS, Ng CG

“…This study aimed to investigate poor adherence prevalence and the demographic and clinical factors associated with poor medication adherence among patients with MDD.Methods: This cross-sectional survey recruited participants using universal sampling from a major hospital in Selangor, Malaysia. …”
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Characteristics and outcomes of women using emergency medical services for third-trimester pregnancy-related problems in India: a prospective observational study by Jennifer A Newberry, Corey B Bills, Elizabeth A Pirrotta, Matthew C Strehlow, G V Ramana Rao, Hyeyoun (Elise) Min, Ann E Evensen, Lawrence Leeman, S V Mahadevan

“…Interfacility transfers, patients absent on ambulance arrival and patients refusing care were excluded.Main outcome measures Emergency medical technician (EMT) interventions, method of delivery and death.Results The median age enrolled was 23 years (IQR 21–25). …”
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Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol of a two-parallel arms target trial emulation study in a multicentre outpatient in... by Emilia Riggi, Marco Barbero, Gian Luca Di Tanna, Ruth Hersche, Andrea Weise

“…The third aim is to perform a cost-effectiveness analysis of EME.Methods and analysis Using observational data, we will emulate a prospective two-parallel arms target trial to assess whether adding EME to the standard care is associated with improved outcomes in patients with long COVID-related fatigue. …”
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Enhanced photocatalytic degradation of Rhodamine B using polyaniline-coated XTiO3(X = Co, Ni) nanocomposites by Mariyem Abouri, Abdellah Benzaouak, Mohamed Elouardi, Lahcen El Hamdaoui, Fatima Zaaboul, Khalil Azzaoui, Belkheir Hammouti, Rachid Sabbahi, Shehdeh Jodeh, Mohammed Alaoui El Belghiti, Adnane El Hamidi

“…Abstract In this study, novel polyaniline-coated perovskite nanocomposites (PANI@CoTiO3 and PANI@NiTiO3) were synthesized using an in situ oxidative polymerization method and evaluated for the photocatalytic degradation of Rhodamine B (RhB) a persistent organic pollutant. …”
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In vitro modeling of feline gut fermentation: a comprehensive analysis of fecal microbiota and metabolic activity by Qianle Ren, Qianle Ren, Yuling Li, Mingmei Duan, Jinjun Li, Fangshu Shi, Yun Zhou, Wanjing Hu, Junfu Mao, Xiaoqiong Li

“…This study aims to identify the optimal in vitro fermentation method for cat gut microbiota by comprehensively analyzing fecal microbiota and fermentation characteristics. …”
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Detecting Deception and Ensuring Data Integrity in a Nationwide mHealth Randomized Controlled Trial: Factorial Design Survey Study by Krista M Kezbers, Michael C Robertson, Emily T Hébert, Audrey Montgomery, Michael S Businelle

“…ObjectiveThis study aimed to develop and implement robust deception detection procedures during the enrollment period of a remotely conducted randomized controlled trial. MethodsA 32-group (2×2×2×2×2) factorial design study was conducted from November 2021 to September 2022 to identify mobile health (mHealth) survey design features associated with the highest completion rates of smartphone-based ecological momentary assessments (n=485). …”
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Muscle power is associated with higher levels of walking capacity and self-reported gait performance and physical activity in individuals with cerebral palsy by Mattie E. Pontiff, Mattie E. Pontiff, Abhinandan Batra, Li Li, Noelle G. Moreau

“…IntroductionThe purpose of this study was to investigate the relationships between a Power Leg Press test (PLP) with walking capacity and self-reported performance and participation in individuals with Cerebral Palsy (CP), and to compare the strength of the associations between two power tests (PLP and isokinetic (IsoK)) with walking capacity.MethodsAmbulatory individuals with CP (n = 33; age 17.89 ± 7.52 years) performed five inclined power leg presses at 40%–50% of their 1-repetition maximum “as fast as possible”. …”
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Association of socioeconomic status with diabetic microvascular complications: a UK Biobank prospective cohort study by Yikeng Huang, Zhi Zheng, Haibing Chen, Chufeng Gu

“…This study aimed to explore whether SES is associated with the risk of diabetic retinopathy (DR), nephropathy (DN) and diabetic peripheral neuropathy (DPN) using large prospective cohort. Methods SES was evaluated using education attainment (individual level), household income (household level), and Townsend deprivation index (TDI, neighborhood level). …”
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Hemodynamics Change and Clinical Efficacy on Cervical Spondylosis of Vertebral Artery Type Treated by Hot Compress Therapy with Medicinal Salt Pillow by Li CHEN, Lijun YAO, Li ZHAO, Chunqiao FU, Xiaoyu XU

“…Objective:To investigate the effect of hot compress therapy with medicinal salt pillow on cervical spondylosis of vertebral artery type, and to observe the effects on symptoms, cervical function and clinical effect of patients.Methods:A total of 80 patients with cervical spondylosis of vertebral artery type were randomly divided into observation group and control group according to the proportion of 1∶1 used by SPSS 17.0 software random sequence generation module, with 40 cases in each group. …”
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Deficiency of ATF3 facilitates both angiotensin II‐induced and spontaneously formed aortic aneurysm and dissection development by activating cGAS–STING pathway by Yifan Du, Poyi Hu, Xiangchao Ding, Dashuai Wang, Jingjing Luo, Sheng Le, Lingyun Ren, Manhua Chen, Ping Ye, Jiahong Xia

“…However, the molecular mechanisms responsible for the phenotypic switch and loss of VSMCs in AAD are not fully understood. Methods and results In this study, we employed a discovery‐driven, unbiased approach. …”
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MAZ-mediated tumor progression and immune evasion in hormone receptor-positive breast cancer: Targeting tumor microenvironment and PCLAF+ subtype-specific therapy by Gaofeng Ni, Yuwei Sun, Hongling Jia, Zhikai Xiahou, Yumeng Li, Fu Zhao, Hongyan Zang

“…Understanding the molecular mechanisms behind this resistance, including tumor heterogeneity and changes in the tumor microenvironment, was crucial for overcoming resistance, identifying new therapeutic targets, and developing more effective personalized treatments. Methods: The study utilized single-cell RNA sequencing (scRNA-seq) data sourced from the Gene Expression Omnibus database and The Cancer Genome Atlas to analyze HR+BC and identify key cellular characteristics. …”
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Development and validation of a nomogram for predicting immune-mediated colitis in lung cancer patients treated with immune checkpoint inhibitors: a retrospective cohort study in C... by Qianjie Xu, Xiaosheng Li, Yuliang Yuan, Guangzhong Liang, Zuhai Hu, Wei Zhang, Ying Wang, Haike Lei

“…This study aimed to identify the clinical risk factors associated with IMC development in patients with lung cancer and to develop a risk prediction model to facilitate personalized treatment and care strategies.MethodsThe data collected included 21 variables, including sociodemographic characteristics, cancer-related factors, and routine blood markers. …”
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A broad assessment of forty-one skin phenotypes reveals complex dimensions of skin ageing by Jun Yan Ng, Qi Yi Ambrose Wong, Jun Jie Lim, Dingyu Cen, Jia Yi Karen Wong, Yi Ying Eliza Lim, Yang Yie Sio, Kavita Reginald, Yee-How Say, Fook Tim Chew

“…We therefore wonder whether the current discourse on skin ageing places a disproportionate amount of focus on a few selected phenotypes, leaving other skin ageing phenotypes underexplored. Methods In this cross-sectional study, we performed a broad assessment of forty-one signs of skin ageing and characterised the phenotypes that constituted key components of skin ageing. …”
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Environmental Life Cycle Assessment of Healthcare Waste Valorisation Alternatives by Zlaugotne Beate, Zandberga Anda, Gusca Julija, Kalnins Silvija Nora

“…The aim of the research is to understand the environmental consequences and potential benefits of treated iHCW valorisation scenarios through the ‘gate-to-gate’ (from iHCW generation at medical facilities to end-of-life or recovery) life cycle assessment framework and to compare it with the existing practice – landfilling with functional unit 1 ton of treated iHCW and using ReCiPe 2016 (Midpoint, Hierarchist perspective) method. Valorisation scenarios (VS) analysed the use of treated HCW as a substitute of feedstock for reinforced asphalt, reinforced cement, RDF, syngas, acoustic panel and plastic components used for hydroponics. …”
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Single, double, and triple-hit strategies to establish a long-term premature rabbit model of bronchopulmonary dysplasia by Chiara Catozzi, Francesca Stretti, Enrica Scalera, Matteo Storti, Angelo Modena, Giorgio Aquila, Gino Villetti, Erica Ferrini, Andrea Grandi, Franco Fabio Stellari, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Christina Brandenberger, Henri Schulte, Xabier Murgia, Maurizio Civelli, Francesca Ricci

“…This study aimed to extend the preterm rabbit model to postnatal day (PND) 14 to mimic the evolving phase of BPD and enable the investigation of therapeutic interventions at later and more relevant time points. Methods Preterm rabbit pups delivered on the 28th day of gestation were either exposed to room air or different degrees of hyperoxia (50% and 70% O2) for 14 days. …”
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Development of an artificial intelligence-based application for the diagnosis of sarcopenia: a retrospective cohort study using the health examination dataset by Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Sung Hyun Lee, Chul Park

“…To address this gap, we propose an artificial intelligence (AI)-based web application that automates the collection of data, classification of the lumbar spine 3 (L3) slices, segmentation of the subcutaneous fat, visceral fat, and muscle areas in the classified L3 slices, and quantitative analysis of the segmented areas. Methods We developed an automated lumbar spine slice classification model using the CNN (EfficientNetV2) algorithm and an automated domain segmentation model to identify the subcutaneous fat, visceral fat, and muscle areas using the U-NET algorithm. …”
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Korelasi Kadar Hemoglobin dengan Kadar Nitric Oxide pada Preeklamsia dan Kehamilan Normal by Siska Helina, Ariadi , Delmi Sulastri

“…In this study, 17 preeclampsia pregnancies and 18 normal pregnancies were taken into samples in the hospitals, where the sample numbers were determined by using consecutive sampling method. The results show that in preeclampsia haemoglobin level is 12.39 ± 2.10g/dl and NO level is 29.88 ± 9.47 µmol, while in normal<br />pregnancy, haemoglobin level is 11.18 ± 0.98g/dl and NO is 84.22 ± 54.26µmol respectively. …”
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Association analysis of suicide risk assessed with Mini International Neuropsychiatric Interviews’ Suicidality Module in adolescents with non suicidal self injury disorder by Shuo Geng, Shuo Geng, Wen Zhang, Xiang Gao, Lele Qu, Xueping Zheng, Jian Sun, Mingdong Xu, Hua Lin, Xueyu Jia, Xu Zhang

“…This study observes the association between depressive and anxiety symptoms and suicide risk among adolescents with non suicidal self injury disorder, and explores the mechanism underlying the high risk of suicide in this population.MethodAdolescents with non suicidal self injury disorder and their parents from a psychiatric outpatient clinic were selected to conduct paper questionnaires to measure their sociodemographic conditions. …”
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Exploring the Psychological and Physiological Insights Through Digital Phenotyping by Analyzing the Discrepancies Between Subjective Insomnia Severity and Activity-Based Objective... by Ji Won Yeom, Hyungju Kim, Seung Pil Pack, Heon-Jeong Lee, Taesu Cheong, Chul-Hyun Cho

“…ObjectiveThis study aims to (1) explore the relationship between subjective insomnia severity, as measured by ISI scores, and activity-based objective sleep parameters obtained through wearable devices; (2) determine whether subjective perceptions of insomnia align with objective measures of sleep; and (3) identify key psychological and physiological factors contributing to the severity of subjective insomnia complaints. MethodsA total of 250 participants, including both individuals with and without insomnia aged 19-70 years, were recruited from March 2023 to November 2023. …”
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