Unraveling Online Mental Health Through the Lens of Early Maladaptive Schemas: AI-Enabled Content Analysis of Online Mental Health Communities by Beng Heng Ang, Sujatha Das Gollapalli, Mingzhe Du, See-Kiong Ng

“…ObjectiveWe aimed to uncover associations between EMSs and mental health problems within OMHCs and examine features of EMSs as they are reflected in OMHCs. MethodsWe curated a dataset of 29,329 posts from widely accessed OMHCs, labeling each with relevant schemas and mental health problems. …”
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Development of a pandemic-related core set of quality indicators for quality and patient safety in University Hospitals in Germany by Janis Evers, Natalie Altschuck, Claudia Mehl, Lilly Rüthrich, Lorenz Harst, Felix Walther, Oliver Steidle, Arnt Suckow, Ruth Hecker, Jochen Schmitt, Max Geraedts

“…Therefore, the aim of this work was to develop a set of indicators suited to detect undesirable developments concerning the provision of inpatient healthcare. Material & methods The study employed a literature review, online surveys, expert interviews, and a multistep evaluation process to develop a core set of quality indicators (QIs) suitable for assessing the resilience of university hospitals during pandemics. …”
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Evaluation of Metabolic Characteristics of Brain Tumours Utilising 31-Phosphorus MR Spectroscopy in 3T MRI: A Cross-sectional Study by Nivetha Kannan, Babu Peter Sathyanathan

“…Aim: To metabolically characterise brain tumours and compare them with normal brain parenchyma using 31-Phosphorus spectroscopy by obtaining applicable parameters for evaluation, diagnosis and grading of brain tumours. Materials and Methods: This cross-sectional study was conducted at the Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India, from December 2019 to December 2021. …”
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Examining the Use of Machine Learning Algorithms to Enhance the Pediatric Triaging Approach by Aljubran HJ, Aljubran MJ, AlAwami AM, Aljubran MJ, Alkhalifah MA, Alkhalifah MM, Alkhalifah AS, Alabdullah TS

“…This model will improve accuracy in pediatric emergency triage by categorizing cases into three urgency levels (nonurgent, urgent, and emergency).Patients and Methods: This is a retrospective observational cohort study that used emergency patient records obtained from the Emergency Department at King Faisal Specialist Hospital & Research Centre. …”
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DESKRIPSI MINAT DAN HASIL BELAJAR SISWA DENGAN MODEL DIRECT INSTRUCTION BERBASIS MIND MAPPING PADA PEMBELAJARAN IPA DI SMPN 3 KEPAHIANG by Aulia Wulandari, Connie Connie, Eko Risdianto

“…ABSTRACT This study aims to describe student’s interest, ability in making mind mapping, and learning outcomes of students with a mind mapping based direct learning model in science learning in SMPN 3Kepahiang. The research method used was descriptive qualitative. The research subjects were students of class VII D SMP Negeri 3 Kepahiang 2018/2019 school year who received 25 students. …”
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Lactate Dehydrogenase-A-Forming LDH5 Promotes Breast Cancer Progression by Fang T, Hu L, Chen T, Li F, Yang L, Liang B, Wang W, Zeng F

“…We aimed to explore the roles of LDHA and LDH5 isoenzyme activity in BC, which provides a new insight into LDHA for the treatment of BC.Methods: The expression of LDHA in BC and its relationship with clinicopathological features were obtained from various databases including The Cancer Genome Atlas (TCGA), Human Protein Atlas (HPA), Breast Cancer-Gene Expression Miner (bc-GenExMiner), TNMplot, UALCAN. …”
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Investigating the associations between personality functioning, cognitive biases, and (non-)perceptive clinical high-risk symptoms of psychosis in the community by Giulia Rinaldi, Stefan Lerch, Frauke Schultze-Lutter, Stefanie Julia Schmidt, Marialuisa Cavelti, Michael Kaess, Chantal Michel

“…Impaired personality functioning is prioritized in recent dimensional personality disorder models (DSM-5, ICD-11), yet underexplored in CHR-P, as are associations with cognitive biases, which early studies indicate as possibly linking CHR-P-symptoms and personality pathology. Methods A community sample (N = 444, 17–60 years, 61.8% female) was assessed via clinical telephone interview and online questionnaires. …”
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Early results of primary total hip arthroplasty performed in young adults at a regional Saudi-Arabian orthopedics center: a prospective observational study by Walid M. Al-Shaer, Ali H. Al-Yami, Mokhtar Ahmed Al-Sayed, Ali Mohammed Al-Zaidan, Emad Ruddah Al-Sufyani, Ahmed A. Khalifa, Raad M. M. Al-Thaqafi, Abdulmohsen H. Al-Hamyani, Mohammed M. Al-Subaie

“…The aim of the study is to report the early experience and clinical results after total hip arthroplasty in patients ≤40 years old from a regional Saudi-Arabian hospital as a representative of the Arab (Middle Eastern) population. Methods. We conducted a prospective observational study over one year by following all patients (≤40 years) who underwent primary THA at a regional Saudi-Arabin orthopedics center. …”
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Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models by Yu-heng Wei, Shu-mian Zhou, Shu-mian Zhou, Shu-mian Zhou, Wen Zhao, Qi Chen, Qiu-hua Wang, Qiu-hua Wang, Mei-ling Yu, Ying-yi Wei, Ting-jun Hu, Ting-jun Hu, Ting-jun Hu

“…This study investigated FNB's impact on inflammatory responses induced by Porcine circovirus type 2 (PCV2) in cell and mouse models.MethodsAn inflammatory model was established in RAW264.7 cells infected with varying PCV2 concentrations. …”
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Effect of Baduanjin exercise combined with Jue-tone music therapy on anxiety and depression in patients with psoriasis vulgaris (健身气功八段锦联合角调式音乐对寻常型银屑病患者焦虑抑郁症状的干预效果)... by HU Wei (胡薇), GONG Yonghong (龚永红)

“…Objective To investigate the effect of Baduanjin exercise combined with Jue-tone Music therapy on anxiety and depression in patients with psoriasis vulgaris. Methods Totally 88 patients with psoriasis vulgaris who discharged from the hospital were randomly divided into three groups: control group (n=29), intervention group A (n=29) and intervention group B(n=30). …”
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Target Groups for a Short Dexamethasone Course among Critically Ill COVID-19 Patients by Armen Oganesyan, Ruslan Menzulin, Yury Surovoy, Andrei Nikiforchin, Kirill Zykov

“…We aimed to evaluate the outcomes of COVID-19 patients admitted to the intensive care unit (ICU) and treated with a short dexamethasone course to determine which patient categories derive the highest benefit. Methods. A retrospective cohort study was conducted using a prospectively collected single-center ICU database (April 1–October 1, 2020). …”
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Multiomic characterization, immunological and prognostic potential of SMAD3 in pan-cancer and validation in LIHC by Tao Zhou, Dan Dan Zhang, Jiejing jin, Jinyang Xie, Jianhua Yu, Chao Zhu, Rong Wan

“…Nevertheless, an extensive examination of the comprehensive pan-cancer impact on SMAD3’s diagnostic, prognostic, and immunological predictive utility has yet to be undertaken. Bioinformatics methods were employed to systematically investigate the potential carcinogenic impact of SMAD3. …”
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Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties by Madiha Kanwal, Humaira Nadeem, Sumra Malik, Saima Maqsood

“…Also in-vitro anti-fungal, anti-bacterial and anti-oxidant activity was performed by using ager well diffusion method and DPPH assay respectively. Moreover, the In-vivo biological evaluation of these derivatives was conducted by using carrageenan-induced hind paw model. …”
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Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer by Sara M Tolaney, Tianyu Li, Edward T Richardson, Judith Agudo, Elizabeth A Mittendorf, Beth Overmoyer, Eric P Winer, Adrienne G Waks, Tanya E Keenan, Nabihah Tayob, Gerburg M Wulf, Victoria Attaya, Leilani Anderson, Ian E Krop, Eliezer M Van Allen

“…The safety and tolerability of trastuzumab emtansine (T-DM1) combined with pembrolizumab is unknown.Methods This was a single-arm phase Ib trial (registration date January 26, 2017) of T-DM1 plus pembrolizumab in metastatic, human epidermal growth factor receptor 2 (HER2)-positive breast cancer. …”
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Prospective multi-centre analysis of rural trauma team development training for medical trainees and traffic law enforcement professionals in Uganda: an interrupted time series stu... by Herman Lule, Micheal Mugerwa, Robinson Ssebuufu, Patrick Kyamanywa, Jussi P. Posti, Michael Lowery Wilson

“…The aim of this study was to determine the feasibility of rural trauma team training amongst medical trainees and traffic law enforcement professionals in Uganda. Methods Prospective multi-centre interrupted time series analysis of an interventional training based on the 4th edition of rural trauma team development course of the American College of Surgeons. …”
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Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database by Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo

“…This study aimed to evaluate the adverse events (AEs) of IDH inhibitors based on the Food and Drug Administration Adverse Event Reporting System (FAERS) database. Methods AE reports for IDH inhibitors (enasidenib, ivosidenib, and olutasidenib) were collected and analyzed from the time of launch through the first quarter of 2024. …”
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Decoding gene expression dynamics in planktonic and biofilm cells of Streptococcus mutans: regulation and role of mutanofactin genes in biofilm formation by Muhammad Afzal, Miguel Carda-Diéguez, Susanne Bloch, Susanne Bloch, Leon G. S. Thies, Alex Mira, Christina Schäffer

“…Mutanofactins, a class of polyketide/non-ribosomal lipopeptide secondary metabolites, are emerging as potential modulators of S. mutans biofilm development.MethodsTranscriptomic analysis was conducted to examine gene expression patterns in S. mutans NMT4863 across distinct growth phases and lifestyles, aiming to identify metabolic factors influencing biofilm formation. …”
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The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study by Wei-Chih Chin, Pao-Hsien Chu, Lung-Sheng Wu, Kuang-Tso Lee, Chen Lin, Chien-Te Ho, Wei-Sheng Yang, I-Hang Chung, Yu-Shu Huang

“…Nonparametric analysis of actigraphy data was performed to examine the circadian rhythm of patients. MethodsPatients with MI in the intensive care unit (ICU) were enrolled alongside age- and gender-matched healthy controls. …”
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The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury by Xiaoxiao Luo, Dongyang Liu, Cuicui Li, Jia Liao, Wuyang Lv, Yuchen Wang, Ruxue Diao, Yingyu Jin

“…The utility of the sCAR (secrum creatinine/albumin) and LAR (Lactate dehydrogenase/albumin) as diagnostic markers for persistent severe SA-AKI remains unclear. Methods We acquired training set data from the MIMIC-IV database and validation set data from the First Affiliated Hospital of Harbin Medical University. …”
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Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology by Jiaying Yang MM, Yuancai Liu MM, He Yao MM, Mengying Sun MM, Yangbo Tong MM, Guanjun Ma MM, Zhuo Chen MD, Xiang Qian MD, Aiqin Zhang MD

“…Objective: To observe the clinical efficacy of Dendrobium officinale in the treatment of radiotherapy-induced oral mucositis in nasopharyngeal carcinoma patients, and to explore its regulating effect on immune function and oral microbiota by comparing immune-related factors and oral microbiota before and after the intervention. Methods: We conducted a randomized double-blinded controlled trial in Zhejiang Cancer Hospital. …”
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