Topical chlorhexidine 0.2% versus topical natamycin 5% for fungal keratitis in Nepal: rationale and design of a randomised controlled non-inferiority trial by Victor Hu, David Macleod, Helen Anne Weiss, Matthew J Burton, Simon Arunga, Astrid Leck, Sanjay Kumar Singh, Jeremy John Hoffman, Reena Yadav, Sandip Das Sanyam, Pankaj Chaudhary, Abhishek Roshan, Einoti Matayan

“…Full-scale randomised controlled trials (RCTs) of topical chlorhexidine 0.2% are warranted to answer this question definitively.Methods and analysis We will test the hypothesis that topical chlorhexidine 0.2% is non-inferior to topical natamycin 5% in a two-arm, single-masked RCT. …”
Get full text

Hubungan antara Indeks Massa Tubuh dengan Kadar Nitrit Oksid pada Masyarakat Etnik Minangkabau di Kota Padang by Nidia Purwadianti, Fadil Oenzil, Delmi Sulastri

“…The secondary data were analyzed by using Pearson correlation and mean difference test by using independent sample test method. The results obtained in obese groupare p-value=0.982 and r= -0.003. …”
Get full text

Evaluation on role of the chest pain nurse in emergency management of patients with ST-elevation myocardial infarction (专职胸痛护士在ST段抬高型急性心肌梗死患者急救中的应用研究)... by QIAN Hongmei (钱宏梅), WEI Yingying (韦莹莹), WANG Yan (王艳)

“…Objective To explore the role of chest pain nurse in the emergency management of patients with ST-elevation myocardial infarction (STEMI). Methods Basing on the requirement of chest pain center construction, a group of chest pain full-time nurses were recruited in emergency room and catheter room for Digital subtraction angiography (DSA), and the emergency care process of STEMI patients was modified. …”
Get full text

Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medica... by Zakhour R, Khafaja S, Korman R, Boutros CF, El Zein Z, Chmaisse A, Haj M, Haddara A, El-Houry Z, Jbahi M, Chamseddine S, Bou Karroum S, Al Oweini D, Youssef YS, Youssef N, Nasser M, Fayad D, Abi Farraj F, El Nakib C, Isaac I, Lteif M, Araj GF, Dbaibo GS

“…The objectives of this study were to describe the epidemiology, potential contributing factors, and antimicrobial resistance patterns associated with infections caused by MDR Gram-negative bacteria (GNB) in non-immunocompromised children and adolescents.Methods: This was a retrospective observational study conducted at the American University of Beirut Medical Center (AUBMC) from 2009 to 2017. …”
Get full text

Four weeks of slow-paced breathing: a longitudinal, randomized, placebo-controlled study of the autonomic nervous system by Nicolas Bourdillon, Arnaud Rochat, Vanessa Hoop, Grégoire P. Millet

“…The goal of this study was to test a personalized SPB training vs. placebo to help disentangle the effects of SPB from those solely linked to breathing awareness or distraction. Methods Twenty-four young healthy volunteers participated in this study. …”
Get full text

Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19 by Juan Antonio Suárez-Cuenca, José Fernando Flores-Zaleta, Leslie Andrea Corona-Rojas, Pablo Guzmán-Rullán, Luis Alfonso Camacho-Barajas, Uzziel Aguilera-Ontiveros, Alberto Melchor-López, Alejandro González-Mora, Perla Marlene Guzmán-Ramírez, Janicia Rodríguez-Solis

“…The present study aimed to evaluate whether the extent of lung involvement and pattern of lung injury, as determined by chest CT-scan, are related with D-Dimer; and further impact clinical prognosis in patients with ARDS due to COVID-19. Methods Longitudinal, prospective, observational, multi-center study. …”
Get full text

Factors and Reasons Associated with Hesitating to Seek Care for Migraine: Results of the OVERCOME (US) Study by Robert E. Shapiro, Eva Jolanda Muenzel, Robert A. Nicholson, Anthony J. Zagar, Michael L. Reed, Dawn C. Buse, Susan Hutchinson, Sait Ashina, Eric M. Pearlman, Richard B. Lipton

“…The aim of this study, in a large adult population sample in the United States (US), was to identify factors associated with and reasons for hesitating to seek healthcare for migraine. Methods The web-based OVERCOME (US) survey study identified adults with active migraine in a demographically representative US sample who answered questions about hesitating to seek care from a healthcare provider for migraine and reasons for hesitating. …”
Get full text

CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1–CXCR2 induced NETs by Yu Liang, Shuang Chen, Zhi Chen, Fang Peng, Qianwen Liu, Gan Xiong, Caihua Zhang, Maosheng Cheng, Rongsong Ling, Demeng Chen, Qimin Zhou

“…Background CD276 (B7-H3), a pivotal immune checkpoint, facilitates tumorigenicity, invasiveness, and metastasis by escaping immune surveillance in a variety of tumors; however, the underlying mechanisms facilitating immune escape in esophageal squamous cell carcinoma (ESCC) remain enigmatic.Methods We investigated the expression of CD276 in ESCC tissues from patients by using immunohistochemistry (IHC) assays. …”
Get full text

Early removal of indwelling urinary catheters in children undergoing abdominal tumor resection with epidural analgesia by Shachi Srivatsa, Jennifer H. Aldrink, Dana Schwartz, Grant Heydinger, Andrew Davidoff, Andrew J. Murphy, Kyle O. Rove, Sara A. Mansfield

“…This study focuses on children undergoing abdominal tumor resection with appropriate EA coverage, to assess whether IUC can be removed early with minimal risk of reinsertion for urinary retention. Methods: A retrospective review of children who underwent abdominal tumor resections with EA between 2015 and 2023 at two institutions was conducted. …”
Get full text

Prevalence of Site-Specific Mycoplasma genitalium Infection and Macrolide and Fluoroquinolone-Associated Mutations in Men Who Have Sex with Men in Shenzhen, China by Leng X, Zhu R, Ao X, Zhou Y, Zhang K, Hu T, Wu J, Chen Z, Huang L, Huang N, Li X, Ahmed Alnour R, Xue Z, Zhang X, Liu H, Axirejiang T, Ke W, Zou H

“…We aimed to assess site-specific MG infection and its correlates and macrolide and fluoroquinolones mutations among men who have sex with men (MSM) in Shenzhen, China.Methods: Samples were obtained from different anatomic sites of MSM based on their sexual behavior. …”
Get full text

Genetic characteristics of influenza A and B viruses circulating in Russia in 2019–2023 by Svetlana B. Yatsyshina, Anna A. Artamonova, Maria A. Elkina, Anna V. Valdokhina, Victoria P. Bulanenko, Aleksandra A. Berseneva, Vasily G. Akimkin

“…Objectives of the study include: analysis of influenza virus circulation in Russia in 2019–2023, phylogenetic and molecular analysis of hemagglutinin (HA) sequences of influenza viruses, detection of mutations associated with drug resistance to neuraminidase (NA) inhibitors and M2-protein (M2) ion channel inhibitors. Materials and methods. Biological samples containing RNA of influenza viruses were studied: 410 A(H1N1)pdm09, 147 A(H3N2) and 167 B(Victoria). …”
Get full text

Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study by Isabell Anna Just, Denis Fries, Sina Loewe, Volkmar Falk, Nikola Cesarovic, Frank Edelmann, Anna Feuerstein, Florian L. Haufe, Michele Xiloyannis, Robert Riener, Felix Schoenrath

“…Abstract Aims The aim of this pilot study was to investigate the safety, feasibility, tolerability, and acceptability of an assisted mobilization of advanced heart failure patients, using a lightweight, exoskeleton‐type robot (Myosuit, MyoSwiss AG, Zurich, Switzerland). Methods and results Twenty patients in functional NYHA class III performed activities of daily life (ADL, n = 10) or participated in a single, standardized, 60 min rehabilitation exercise unit (REU, n = 10) with and without the Myosuit. …”
Get full text

Ultrasonic assisted stir squeeze casting of AA5456/Al2O3–SiC-Gr-MoS2 hybrid nanocomposites: Microstructure and strengthening analysis by B.N. Akash Deep, S. Rajanna, K.N. Krishnamurthy, G.C. Manjunath Patel, T. Ganesha, G.V. Gnanedra Reddy, Mudassir Hasan, Emanoil Linul

“…The Quadratic Summation and Arithmetic Summation methods effectively predict the YS of the prepared AMMHNCs, with predictions closely aligning with experimental results.…”
Get full text

VECTOR: Velocity-Enhanced GRU Neural Network for Real-Time 3D UAV Trajectory Prediction by Omer Nacar, Mohamed Abdelkader, Lahouari Ghouti, Kahled Gabr, Abdulrahman Al-Batati, Anis Koubaa

“…This approach is designed to improve the predictive capabilities over traditional methods that rely solely on recurrent neural networks (RNNs) or transformers, which can struggle with scalability in this context. …”
Get full text

Composite Sorbents Based on Chitosan Polymer Matrix and Derivatives of 4-Amino-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide for Uranium Removal from Liquid Mineralized Media by Anna I. Matskevich, Konstantin V. Maslov, Veronika A. Prokudina, Daria D. Churakova, Oleg Yu. Slabko, Dmitry K. Patrushev, Nikita S. Markin, Eduard A. Tokar’

“…A complex of physicochemical analysis methods indicates that the direct introduction of a matrix with high ionic permeability into the reaction mixture contributes to the formation of homogeneous particles of composite with developed surface morphology, which enhances the kinetic and capacitive parameters of uranium sorption in liquid media. …”
Get full text

Factors Associated with Management of Workplace Violence Competence Among Chinese Nursing Interns by Meng L, He L, Ouyang L, Fu M, Li P, He Y

“…Therefore, this study investigated the current status of management of workplace violence competence (MWVC) and identify associated factors affecting their MWVC among nursing interns.Participants and Methods: A total of 817 nursing interns from six tertiary hospitals in Hunan Province, China, participated in this study in July 2023. …”
Get full text

Gambaran Pengetahuan dan Sikap Mahasiswa Fakultas Kedokteran Universitas Andalas tentang Rokok by Yosantaraputra ., Yanwirasti ., Abdiana .

“…The purpose of this study was to determine the knowledge and attitude of students of the Faculty of Medicine, University of Andalas about Cigarettes.This is a descriptive research method and the sample with drawal is done by using Simple Random Sampling technique witha sample size of 273 people. …”
Get full text

Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…To apply refined OMVs for human theranostic applications, we developed naturally exposed receptor-binding domain (RBD) OMVs grafted with antigen 43 as a minimal modular system targeting angiotensin-converting enzyme 2 (ACE2).Methods: We constructed E. coli-derived OMVs using the antigen 43 autotransporter system to display RBD referred to as viral mimetic Ag43β 700_RBD OMVs. …”
Get full text

Enhancing elemental release and antibacterial properties of resin-based dental sealants with calcium phosphate, bioactive glass, and polylysine by Phatpicha Lertwisitphon, Yotsavee Worapasphaiboon, Nichapa Champakanan, Arnit Toneluck, Parichart Naruphontjirakul, Anne M. Young, Rattapha Chinli, Phoom Chairatana, Supanan Sucharit, Piyaphong Panpisut

“…The physical properties, mechanical performance, cytotoxicity, and inhibition of S. mutans biofilm by these materials were subsequently evaluated. Methods Five experimental dental sealants were formulated as follows: F1 (M6B6P6), F2 (M6B6P3), F3 (M3B3P6), F4 (M3B3P3), and F5 (M0B0P0, serving as the control). …”
Get full text

Establishment and maturation of gut microbiota in White King pigeon squabs: role of pigeon milk by Xiaoqin Xu, Xiaoqin Xu, Zihan Wang, Zihan Wang, Yi Jian, Long Zhang, Long Zhang, Caiquan Zhou, Caiquan Zhou, Li Liu, Hui Liu

“…This study aims to elucidate the establishment characteristics of the gut microbiota in White King pigeon squabs and explore the role of pigeon milk in this process.MethodsThis study employed 16S rRNA sequencing technology to investigate the dynamics of microbial composition in feces and pigeon milk at various growth stages of White King pigeon. …”
Get full text