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116481
The prevalence and antimicrobial resistance of respiratory pathogens isolated from feedlot cattle in Canada
Published 2025-01-01“…ObjectivesThe purpose of this study was to characterize the prevalence of antimicrobial resistance in Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni isolated from healthy feedlot cattle over 2 years, and investigate factors potentially associated with recovery of resistant isolates.MethodsDeep-guarded nasopharyngeal (NP) swabs were used to sample feedlot cattle in multiple randomly selected feedlots (2019 n = 21, 2020 n = 26) at 2 timepoints. …”
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116482
Post-therapeutic support and rehabilitation for breast cancer women in complete remission in a thermal resort: study protocol for the PACThe Real-Life conditions observational tria...
Published 2025-01-01“…The aim of this study is therefore to confirm the benefits of the PACThe program at six months for breast cancer women in complete remission in real-life conditions. Methods The project PACThe Real-Life conditions is an observational trial in which 400 breast cancer women in complete remission will be sent to a 3 week thermal “post-cancer rehabilitation” program. …”
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116483
Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis
Published 2025-01-01“…This study aimed to investigate the shared genes among three AIDs—Multiple Sclerosis (MS), Systemic Lupus Erythematosus (SLE), and Rheumatoid Arthritis (RA) using bioinformatics databases, and to identify potential biomarkers for early diagnosis.MethodsWe retrieved transcriptomic data of MS, SLE, and RA patients from public databases. …”
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116484
A perinatal psychiatry access program to address rural and medically underserved populations using telemedicine
Published 2025-01-01“…Perinatal Psychiatry Access Programs have emerged as a successful model to increase the capacity of front-line maternal health care providers to address perinatal mental health conditions through education, consultation, and increased resources and referrals. Methods This model has been adapted in South Carolina to include direct access to mental health treatment in response to inadequate maternity care and mental health services, including a large proportion of rural, Medically Underserved Areas in Primary Care and Mental Health Healthcare Provider Shortage Areas throughout the state. …”
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116485
Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity
Published 2025-01-01“…Previously, we discovered that β-cell autophagy is impaired prior to the onset of T1D, implicating this pathway in T1D pathogenesis.AimsTo assess the role of autophagy in β-cell health and survival, and whether defects in autophagy render islets more immunogenic.MethodsWe knocked out the critical autophagy enzyme, ATG7, in the β-cells of mice (ATG7Δβ-cell) then monitored blood glucose, performed glucose tolerance tests, and evaluated bulk islet mRNA and protein. …”
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116486
The Usefulness of Soluble ST2 Concentration in Heart Failure with Reduced Ejection Fraction to Predict Severe Impairment in Exercise Capacity Assessed in Cardiopulmonary Exercise T...
Published 2024-12-01“…Our objective was to evaluate the relationship between the selected cardiopulmonary exercise testing (CPET) parameters and the concentration of novel biomarker sST2 in a group of patients with heart failure with reduced ejection fraction (HFrEF). <b>Methods</b>: A group of 135 patients with HFrEF was enrolled in this prospective cohort study. …”
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116487
Olfactory mucosa-mesenchymal stem cells with overexpressed Nrf2 modulate angiogenesis and exert anti-inflammation effect in an in vitro traumatic brain injury model
Published 2025-02-01“…At present, the effects of OM-MSCs with overexpressed Nrf2 in brain diseases remain to be explored. Methods The OM-MSCs were prepared and transfected with Nrf2 overexpression plasmid. …”
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116488
Feasibility and Safety of the C1 “Zero Angle” Screw: A Novel “In–Out–In” Technique for Atlantoaxial Dislocation
Published 2025-02-01“…We evaluated the feasibility of C1 “Zero Angle” screw (C1ZAS) and safe entry point with “in–out–in” technique as an alternative option for C1 pedicle screw (PS) in cases with AAD. Methods Sixty‐one patients with AAD or atlantoaxial instability (AAI) (45 male and 16 female) who underwent cervical computed tomography and magnetic resonance imaging scans in our center between January 1, 2022 and December 31, 2023 were retrospectively reviewed. …”
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116489
Effect of High Frequency Repetitive Transcranial Magnetic Stimulation on Postoperative Cognitive Dysfunction in Elderly Mice Based on BDNF/TrkB Signaling Pathway
Published 2024-01-01“…ObjectiveTo investigate the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on postoperative cognitive dysfunction (POCD) in aged mice,and analyze its mechanism.MethodsA total of 24 18 month old C57BL/6J male aged mice were randomly divided into control group,operation group and rTMS group,with 8 mice in each group. …”
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116490
Pooling the complex survey data across the 64 lower and middle-income countries: A study on antibiotic usage in under-five children
Published 2025-01-01“…As a result, it's crucial to look at the variables that affect antibiotic exposure and highlight the subgroups among whom antibiotic abuse is the most prevalent. Methods: We used the most recent standard Demographic and Health Survey (DHS) data for 64 LMICs. …”
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116491
Association Between Fentanyl Use and Post-Intubation Mean Arterial Pressure During Rapid Sequence Intubation: Prospective Observational Study
Published 2024-11-01“…Therefore, our study aimed to examine the association of change in mean arterial pressure (MAP) with and without the use of a predetermined dose of 50 micrograms (μg) intravenous fentanyl as a pretreatment agent during RSI. Methods: This prospective observational study included patients undergoing RSI at an academic emergency department (ED) over a three-year period between January 1, 2018–January 1, 2021. …”
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116492
A dehazing and enhancement algorithm for heterogeneous images of underground mining environments in coal mines
Published 2025-01-01“…Hence, this study proposed a dehazing and enhancement algorithm for heterogeneous images of underground mining environments. Methods Initially, hazy images were segmented into zones with different brightness values, for which the average ambient light intensity of global dark channels was calculated. …”
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116493
Effects of a 10-week athletic performance program on match performance variables in male professional football players
Published 2025-01-01“…The APP was designed to target mobility, stability, strength, multidirectional and sprint skills, which are critical for performance during competitive matches.MethodsA prospective quasi-experimental study was conducted over three consecutive seasons. …”
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116494
Inequalities in total fertility rate in Sierra Leone, 2008–2019
Published 2025-02-01“…This study investigated the inequalities in total fertility rate among women in Sierra Leone between 2008 and 2019. Methods We utilized data from the three rounds of the Sierra Leone Demographic Health Survey conducted in 2008, 2013, and 2019. …”
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116495
Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection
Published 2020-01-01“…In this study, epidemiological investigations were conducted in the Zhejiang province to understand the epidemiology and clinical characteristics of asymptomatic patients with COVID-19. Methods. This retrospective study was carried out on 22 asymptomatic patients and 234 symptomatic patients with COVID-19 who were hospitalized in Zhejiang Duodi Hospital from January 21 to March 16, 2020. …”
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116496
Code-Switching in Algerian English as a Foreign Language Speakers’ Facebook Interactions: Exploring Functions and Motives
Published 2024-12-01“…The research was conducted with second-year English-major students at Batna 2 University, analyzing their Facebook interactions to uncover the purposes and underlying reasons for code-switching. A mixed-methods approach was adopted to provide both quantitative and qualitative insights. …”
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116497
Utilisation of the Innovative [18F]-Labelled Radiotracer [18F]-BIBD-071 Within HR+ Breast Cancer Xenograft Mouse Models
Published 2025-01-01“…The MCF-7 cell line, which is hormone receptor-positive (HR+), was used in the assessment of the novel [18F]-labelled radiotracer [18F]BIBD-071 via positron emission tomography (PET) imaging of an HR+ breast cancer xenograft model. <b>Methods:</b> [18F]BIBD-071 was synthesised, radiolabelled, and then subjected to in vitro stability testing. …”
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116498
Spatial analysis of measles cases and vaccination coverage in the Somali region, eastern Ethiopia
Published 2025-02-01“…It can be prevented by two doses of the measles vaccine, either alone or in combination with measles-rubella (MR), which is a low-cost strategy for lowering morbidity and mortality among children.ObjectivesTo conduct spatial analysis of measles cases and vaccination coverage in the Somali region, Eastern Ethiopia.MethodsThis retrospective study was done by using public health emergency directorate measles data from 2022 to 2023 and four years (July 2019–July 2023) of vaccination data from district health information system version 2.36. …”
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116499
Comparisons of computer simulations and experimental data for capacitive hyperthermia using different split-phantoms
Published 2024-12-01“…However, the ability of CHT to induce significant heating throughout the body is under debate.Objectives To perform a pilot study involving comparisons of computer simulations and experimental data using different split-phantoms to validate hyperthermia treatment modeling for pre-planning for a clinical CHT system and to investigate the feasibility of split-phantom measurements in capacitive hyperthermia.Materials and methods The CHT system EHY-2030 (Oncotherm, Budapest, Hungary) was used. …”
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116500
Effect of Traditional Chinese Medicine collapse stains combined with western medicine in treating acute herpes zoster (中药溻渍联合西医治疗急性期带状疱疹的疗效观察)...
Published 2022-09-01“…Objective To investigate the effect of Traditional Chinese Medicine (TCM) collapse stains combined with western medicine in treating acute herpes zoster. Methods A total of 60 patients with acute herpes zoster were randomly divided into observation group and control group, with 30 cases in each group. …”
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