FIRST RUSSIAN EXPERIENCE OF USING THE INTEGRATED SYSTEM OF LASER THERMOABLATION THERAPY IN THE TREATMENT OF METASTATIC LIVER CANCER by D. V. Sidorov, S. O. Stepanov, M. V. Lozhkin, L. O. Petrov, O. V. Gutz, A. A. Kostin, A. G. Isaeva

“…This article presents two observations of the clinical application of the laser ablator “Echolaser X4”: open laser ablation of the metastatic focus with subsequent atypical liver resection and percutaneous laser ablation of the metastasis of the neuroendocrine tumor into the liver. …”
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Comparison of Conventional Open Thyroidectomy and Endoscopic Thyroidectomy via Breast Approach for Papillary Thyroid Carcinoma by Zhuo Tan, JiaLei Gu, QianBo Han, WenDong Wang, KeJing Wang, MingHua Ge, JinBiao Shang

“…The rates of lymph node metastasis in endo group and open group were 23.5% (8/34) and 13.3% (4/30), respectively, without statistically significant difference (P=0.351). …”
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Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach by Amir Taherkhani, Parita Khodadadi, Lida Samie, Zahra Azadian, Zeynab Bayat

“…Mitogen-activated protein kinase 3 (MAPK3) mediates the onset, progression, metastasis, drug resistance, and poor prognosis in various malignancies, including glioma, liver, ovarian, thyroid, lung, breast, gastric, and oral cancers. …”
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Features of diagnosis and treatment of gastrointestinal stromal tumors by N. I. Bogomolov, T. V. Burdinskaya, M. A. Goncharova, A. G. Goncharov, N. N. Tomskikh

“…In the remote period after surgery one patient died due to tumor metastasis, in 7 patients GIST was primarily diagnosed at the autopsy. …”
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Cutaneous Metastases from Primary Hepatobiliary Tumors as the First Sign of Tumor Recurrence following Liver Transplantation by Adam T. Hauch, Joseph F. Buell, Margit McGowan, Parisha Bhatia, Eleanor Lewin, Mary Killackey, Nathan J. Shores, Luis A. Balart, Martin Moehlen, Bob Saggi, Anil S. Paramesh

“…Cutaneous metastasis from hepatobiliary tumors is a rare event, especially following liver transplantation. …”
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Pseudomyxoma Peritonei Originating from Transverse Colon Mucinous Adenocarcinoma: A Case Report and Literature Review by Yingbo Gong, Xin Wang, Zhi Zhu

“…It was diagnosed during resective surgery, involved ovarian metastasis, and survival was short. We did an extensive literature review in order to describe the clinical characteristics, histopathological findings, genetic profile, and potential treatments of PMP caused by nonappendiceal mucinous adenocarcinoma.…”
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Prognostic significance of tumor angiogenesis markers in advanced cervical cancer undergoing chemotherapy by I Nyoman Bayu Mahendra, I Gde Sastra Winata, William Alexander Setiawan, Ida Bagus Agung Widnyana Putra, Putu Bagus Darmayasa

“…Studies have demonstrated significant correlations between VEGF levels and important prognostic parameters, including tumor size, metastasis, and chemotherapy response. Consequently, tumor angiogenesis markers like VEGF and VEGFR hold potential as valuable predictive tools to guide the management of advanced cervical cancer, particularly in patients undergoing chemotherapy.…”
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A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology by Yanhua Fang, Yanhua Fang, Juan Pan, Piao Wang, Piao Wang, Ruoyu Wang, Shanshan Liang

“…Numerous studies have demonstrated that Schisandrin B exhibits significant antitumor activity against various malignant tumors in preclinical studies, which is achieved by inhibiting cell proliferation and metastasis and promoting apoptosis. As a potential antitumor agent, Schisandrin B holds broad application prospects. …”
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Colgajo bilobulado de Esser modificado para su empleo en localización atípica. Presentación de un caso by Carla María García San Juan, José Daniel Gil Milá

“…Es la segunda neoplasia cutánea más frecuente dentro de las de tipo no melanoma, con predominio de 2,1: 1 en la relación hombre-mujer y el cáncer que con más frecuencia causa metástasis. Esta presentación de caso tiene como objetivo describir la técnica quirúrgica del colgajo bilobulado de Esser para la resección de un carcinoma epidermoide situado en el canto externo del ojo, técnica no indicada para esta región de la cara, pero con la se obtuvo un resultado satisfactorio en el tratamiento a una paciente de color de piel blanca, de 75 años que acudió al Servicio de Cirugía Máxilofacial del Hospital General de Cienfuegos, remitida por el Servicio de Dermatología, debido a la presencia de una lesión ulcerada de aproximadamente 5 cm., de diámetro localizada en la mencionada región. …”
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Association of XRCC3, XRCC4, BAX, and BCL-2 Polymorphisms with the Risk of Breast Cancer by Emre Ozoran, Fadime Didem Can Trabulus, Duygu Erhan, Bahadir Batar, Mehmet Guven

“…Breast cancer risk was 5.43 times more in individuals with AA genotype of Bax G(-248) A (rs4645878) (P=0.002). The risk of metastasis was 11 times with this genotype. It was associated with 6 times more risk of having a tumor larger than 2 cm. …”
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Mechanisms and therapeutic implications of gene expression regulation by circRNA-protein interactions in cancer by Nan Zhang, Xinjia Wang, Yu Li, Yiwei Lu, Chengcheng Sheng, Yumeng Sun, Ningye Ma, Yisheng Jiao

“…Studies have demonstrated that circRNAs can interact with RNA-binding proteins (RBPs), which play crucial roles in tumorigenesis, metastasis, and drug response in cancer by influencing gene expression and altering the processes of tumor initiation and progression. …”
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A case report of infantile fibrosarcoma with BRAF gene mutation with incomplete intestinal obstruction by Fan Zhu, Liang Fan, Guanhua Cui, Hai Jian, Hongjie Zhou, Jianfeng Xu, Fengshun Chen

“…Postoperative follow-up over 8 months showed no recurrence or metastasis on abdominal ultrasound. A review of this case alongside 20 reported cases of intestinal IFS revealed that intestinal perforation and obstruction were the most common presentations, with favorable overall prognoses.ConclusionIntestinal IFS is a rare soft tissue sarcoma predominantly occurring in early infancy. …”
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Esophageal submucosal gland duct adenoma: a case report and literature review by Bing Zhou, Jian Zheng, Ling Huang, Hua Hao

“…Local tumor resection was performed, the longest follow-up period was 132 months of the 20 patients, the prognosis was favorable, and no recurrence or metastasis.DiscussionESGDA is more common in the lower esophagus in elderly patients, and its clinical symptoms are atypical. …”
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A Rare Form of Melanoma Masquerading as a Diabetic Foot Ulcer: A Case Report by Susan Thomas, Yuan-Xiang Meng, Vijaykumar G. Patel, Gregory Strayhorn

“…Subsequent definitive wide excision and sentinel node biopsy confirmed ALM with metastasis to inguinal lymph nodes (stage IIIb). The treatment included wide margin excision of the lesion with en bloc amputations of 4th and 5th toes, followed by adjuvant chemotherapy. …”
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Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells by Minkoo Seo, Seung Min Kim, Eun Young Woo, Ki-Cheol Han, Eun Joo Park, Seongyeol Ko, Eun wook Choi, Mihue Jang

“…Cancer stem cells (CSCs) with self-renewal abilities endorse cellular heterogeneity, resulting in metastasis and recurrence. However, there are no promising therapeutics directed against CSCs. …”
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Bisphosphonate-Related Osteonecrosis of the Jaw: A Review of the Literature by Eder Alberto Sigua-Rodriguez, Renato da Costa Ribeiro, Ana Caroline Ramos de Brito, Natalia Alvarez-Pinzon, José Ricardo de Albergaria-Barbosa

“…Bisphosphonates (BPs) are a class of drugs used to treat osteoporosis and malignant bone metastasis. BPs show high binding capacity to the bone matrix, especially in sites of active bone metabolism. …”
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POTENCY OF SOURSOP LEAF EXTRACT AND CURCUMIN WITH MAGNETIC AND MUCUS-PENETRATING NANOPARTICLE AS COLORECTAL CANCER ALTERNATIVE THERAPY by Faiza Rahma Ebnudesita, Ayik Rochyatul Jannah, Savira Butsainah Dienanta, Reny I'tishom

“…Curcumin works molecularly on cyclooxygenase-2 (COX-2) to prevent inflammation, thereby inhibit the growth of cancer cells and reducing the risk of metastasis. Curcumin also plays a role in the inhibition of nuclear factor κ-light-chain-enhancer of activated B (NF-κB) cells, thus inhibits carcinogenesis. …”
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Sinonasal Melanoma: A Case Report and Literature Review by I. S. S. Alves, L. G. S. Berriel, R. T. Alves, M. B. Pinto, C. F. P. Oliveira, A. C. Cazzotto, W. V. Moura

“…The patient remains healthy, with no metastasis or recurrence. He is currently being monitored by the clinical oncology team.…”
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Tumor Markers in Pleural Fluid: A Comprehensive Study on Diagnostic Accuracy by Vladimir Aleksiev, Daniel Markov, Kristian Bechev

“…These effusions are a leading cause of debilitating dyspnea and a diminished quality of life among cancer patients, with distant metastasis to the pleural layers occurring in about 20% of cases during treatment. …”
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MicroRNAs as Immunotherapy Targets for Treating Gastroenterological Cancers by Yixin Yang, Christopher Alderman, Ayoub Sehlaoui, Yuan Xiao, Wei Wang

“…Gastroenterological cancers are characterized by late diagnosis, metastasis, high recurrence, and being refractory to current therapies. …”
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