Implication of protein post translational modifications in gastric cancer by Houji Song, Mingze Zhang, Chengwang Guo, Xi Guo, Yuqi Ma, Yuntao Ma, Yuntao Ma

“…The diverse realm of PTM and PTM crosstalk is linked to many critical signaling events involved in neoplastic transformation, carcinogenesis and metastasis. This review provides a comprehensive overview of the impact of PTM on the occurrence and progression of GC. …”
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The Regulation between CD4+CXCR5+ Follicular Helper T (Tfh) Cells and CD19+CD24hiCD38hi Regulatory B (Breg) Cells in Gastric Cancer by Ying Zhang, Jun Wu, Haibo Zhang, Chen Wu

“…Moreover, higher Tfh% was associated with lymphatic metastasis, patients’ worse outcomes and Breg%. Tfh differentiation and CXCL13 were upregulated by cocultured B cells in vitro, while Tfh cells seem to not participate in Breg cell differentiation from B cells. …”
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GLI1-altered mesenchymal tumor involving the parietal pleura: case report and literature review by Yuanli Zhong, Baizhou Li, Gangping Wang, Yuqing Liu, Zhenwei Chen

“…We conducted a review of all cases of recurrence and metastasis, concluding that this type of tumor has a distinct propensity to metastasize to the lungs. …”
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Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis by Liliana R. Balahura, Aida Selaru, Sorina Dinescu, Marieta Costache

“…During this event, proinflammatory cytokines are produced by numerous types of cells, such as fibroblasts, endothelial cells, macrophages, and tumor cells, and are able to promote the initiation, progression, and metastasis of different types of cancer. When persistent inflammation occurs, activation of inflammasome complexes is initiated, leading to its assembly and further activation of caspase, production of proinflammatory cytokines, and pyroptosis induction. …”
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Prognostic value of immune biomarkers in melanoma loco-regional metastases. by Emilia Hugdahl, Sura Aziz, Tor A Klingen, Lars A Akslen

“…Negative tumour PD-L1 expression was significantly associated with low CD8 and PD-L1 TIL count, large lymph node metastasis tumour size and presence of necrosis in lymph node metastases. …”
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Primary Signet-Ring Cell Adenocarcinoma of the Urinary Bladder Treated with Partial Cystectomy: A Case Report and Review of the Literature by Umesh Jayarajah, D. M. Hilary Fernando, Kasun Bandara Herath, M. V. Chandu de Silva, S. A. S. Goonewardena

“…Partial cystectomy may be considered in patients with localised tumour without evidence of metastasis and poor general condition. Regular cystoscopies and ultrasound imaging are necessary for follow-up and early identification of recurrences.…”
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Adenocarcinoma with Neuroendocrine Differentiation of the Colon Accompanying Osteoclast-Like Giant Cells by Mitsuhiro Tachibana, Tadahiro Isono, Yutaka Tsutsumi

“…Neuroendocrine differentiation in colorectal cancer is reportedly associated with poorer grade of tumor differentiation, nodal and distant metastasis, and other unfavorable features, contributing to a worse clinical outcome. …”
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Bednar Tumour Occurring after Malignant Melanoma Excision by Amedeo Ferlosio, Monia Di Prete, Piero Rossi, Elena Campione, Augusto Orlandi

“…Preoperative clinical diagnosis was “in-transit” melanoma metastasis. After surgical excision, histopathologic examination revealed a dermal nodular proliferation of spindle cells arranged in storiform pattern, with mild pleomorphism, infiltrating around appendages and into the subcutaneous tissue. …”
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Relationship between the ultrasound features of different molecular subtypes of breast cancer and positive PD-1/PD-L1 expression by Ruiqian Yan, Haixia Li, Junxi Gao

“…Among 112 PD-1-positive cases, most luminal B cases exhibited ill-defined margins, while distant metastasis was more common in triple-negative cases. …”
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Lymphatic vessel network injury reduces local tumor control despite preservation of the tumor-draining lymph node by Lauren N. Liebman, Yang Shen, Zachary S. Buchwald, Zhanna Nepiyushchikh, Zhiming Qi, Andrés J. García, J. Brandon Dixon

“…Abstract The lymphatic system plays complex, often contradictory, roles in many cancers, including melanoma; these roles include contributions to tumor cell metastasis and immunosuppression in the tumor microenvironment as well as generation of antitumor immunity. …”
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Simultaneous paratesticular liposarcomas with histopathological differences. A Case report by Pedro León Acosta, Pedro Rosales Torres

“…Liposarcoma is a mesenchymal origin tumor that commonly occurs in the retroperitoneum; It is slow growing and its ability to produce metastasis depends on its histological type. The purpose of this work is to present a case of simultaneous paratesticular liposarcomas with different histological types, in an 80-years-old male patient with a health history and low socioeconomic level; For two years he had been experiencing an increase in volume in the left inguinal region and ipsilateral testicle, which at first was painless; Then, as it increased in size, it became painful, covering the entire right inguinoscrotal region. …”
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Pumilio RNA-Binding Family Member 1 Plays a Promoting Role on Pancreatic Cancer Angiogenesis by Haisu Dai, Yan Jiang, Zhipeng Liu, Xingxing Su, Yishi Yang, Zhiyu Chen

“…Our previous studies showed that Pumilio RNA-binding family member 1 (PUM1) gene is abnormally expressed in pancreatic cancer (PC) tissues, and its knockdown suppresses the growth and metastasis of PC cells. Here, we aimed to further investigate its role in angiogenesis. …”
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Anaesthesia affects immune function and impact on long-term cancer prognosis: A review by Kisdyanti Yuniar Melissa, Suandika Made, Rahmawati Arni Nur

“…This article aims to identify and evaluate the evidence on the effects of anaesthesia-induced immunosuppression, to determine the mechanisms by which anaesthesia affects the immune system during surgery, and the implications for cancer proliferation, metastasis, and recurrence. In addition, this article also evaluates the type of anaesthesia and explores the relationship between immune modulation during anaesthesia and long-term survival. …”
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The Prognostic Implication of the BRAF V600E Mutation in Papillary Thyroid Cancer in a Chinese Population by Ziheng Ye, Xiaotian Xia, Peipei Xu, Wenfei Liu, Shoufei Wang, Youben Fan, Minggao Guo

“…We further demonstrated that larger tumor size (>1 cm), extrathyroidal extension (ETE), and lateral lymph node metastasis (LNM) were associated with a higher probability of PTC recurrence in patients harboring the BRAF V600E mutation. …”
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Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals by Ghyda Murad Hashim, Mehdi Shahgolzari, Kathleen Hefferon, Afagh Yavari, Srividhya Venkataraman

“…A multifactorial and multitargeted approach is required towards intervention of the multitude of signaling pathways associated with carcinogenesis inclusive of angiogenesis and metastasis. In this context, plants provide an immense source of phytotherapeutics that show great promise as anticancer drugs. …”
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Long noncoding RNA DHRS4 antisense RNA 1 suppresses osteosarcoma cell proliferation and promotes apoptosis through a competitive endogenous RNA mechanism by Zhouzhou Tang, Zhihao Li, Guofeng Wu, Jianjun Li, Jianye Tan, Lixin Zhu

“…Recent evidence suggests that the novel long noncoding RNA DHRS4 antisense RNA 1 (DHRS4-AS1) serves an important role in cancer progression and metastasis. However, its function and molecular mechanism in OS remain largely unknown. …”
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RADIUM-223. PLACE IN THE TREATMENT OF METASTATIC CASTRATION-REFRACTORY PROSTATE CANCER by A. A. Kostin, A. G. Muradyan, A. O. Tolkachev, S. V. Popov

“…The most common localization of prostate cancer metastasis is the skeletal bone, which affects up to 90% of cases.At the same time, taking into account the increase in the morbidity of prostate cancer pathology, it dictates the need to search for new, more effective methods of treatment for this group of patients. …”
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The Pivotal Immunomodulatory and Anti-Inflammatory Effect of Histone-Lysine N-Methyltransferase in the Glioma Microenvironment: Its Biomarker and Therapy Potentials by Seidu A. Richard, Kuugbee D. Eugene

“…EZH2 is well recognized as an essential modulator of cell invasion as well as metastasis in glioma. EZH2 oversecretion was implicated in the malfunction of several fundamental signaling pathways like Wnt/β-catenin signaling, Ras and NF-κB signaling, PI3K/AKT signaling, β-adrenergic receptor signaling, and bone morphogenetic protein as well as NOTCH signaling pathways. …”
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Angiogenesis in Spontaneous Tumors and Implications for Comparative Tumor Biology by C. Benazzi, A. Al-Dissi, C. H. Chau, W. D. Figg, G. Sarli, J. T. de Oliveira, F. Gärtner

“…Angiogenesis is a prognostic indicator for a variety of tumors, and it coincides with increased shedding of neoplastic cells into the circulation and metastasis. Several molecules such as cell surface receptors, growth factors, and enzymes are involved in this process. …”
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False Positive 18F-FDG Uptake in Mediastinal Lymph Nodes Detected with Positron Emission Tomography in Breast Cancer: A Case Report by Gamze Uğurluer, Mustafa Kibar, Sinan Yavuz, Akin Kuzucu, Meltem Serin

“…It is accepted that lymph node involvement with metastatic tumor and the presence of distant metastasis are the most important prognostic factors. …”
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