Modern Prospection for Hepatic Arterial Infusion Chemotherapy in Malignancies with Liver Metastases by Yi-Hsin Liang, Yu-Yun Shao, Jia-Yi Chen, Po-Chin Liang, Ann-Lii Cheng, Zhong-Zhe Lin

“…Malignancy with liver metastasis plays an important role in daily oncology practice, especially for primary cancers of the gastrointestinal tract and hepatopancreatobiliary system. …”
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Unravelling the prognostic and operative role of intratumoural microbiota in non‐small cell lung cancer: Insights from 16S rRNA and RNA sequencing by Fuling Mao, Zixuan Hu, Ruifeng Shi, Hongbing Zhang, Zihe Zhang, Yongwen Li, Xuanguang Li, Penghu Gao, Jinhui Li, Minghui Liu, Hongyu Liu, Jun Chen

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Influence of urokinase gene-knockout in C57BL/6-PlautmI. IBugThisPlau6FDhu/GFDhu mice on growth factors in malignant melanoma by E. M. Frantsiyants, I. V. Kaplieva, I. V. Neskubina, V. A. Bandovkina, L. K. Trepitaki, E. I. Surikova, N. D. Cheryarina, L. A. Nemashkalova, N. S. Lesovaya

“…In uPA gene-knockout females, lower levels of TGF-β1 were observed in tumors – by 1.4 times inhibited metastasis, but not completely, and solitary metastatic foci were registered in the lungs. …”
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Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy by Coraline Radermecker, Pascale Hubert, Patrick Roncarati, Stephanie Demoulin, Charlotte Pilard, Marie Ancion, Celia Reynders, Thomas Lerho, Diane Bruyere, Alizee Lebeau, Margot Meunier, Marie-Julie Nokin, Elodie Hendrick, Olivier Peulen, Philippe Delvenne, Michael Herfs

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Genomic insights into familial adenomatous polyposis: unraveling a rare case with whole APC gene deletion and intellectual disability by Hiroki Tanabe, Masami Ijiri, Kenji Takahashi, Honoka Sasagawa, Tomomi Kamanaka, Shohei Kuroda, Hiroki Sato, Takeo Sarashina, Yusuke Mizukami, Yoshio Makita, Toshikatsu Okumura

“…Abstract A young patient diagnosed with advanced colon cancer and liver metastasis was found to have familial adenomatous polyposis (FAP) through comprehensive genomic analysis. …”
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Purulent Pericarditis after Liver Abscess: A Case Report by María Fidalgo García, Juan Carlos Rodríguez Sanjuán, María Riaño Molleda, Marta González Andaluz, Hector Real Noval, Manuel Gómez Fleitas

“…We present the case of a 49-year-old woman, with previous clinical antecedents of recent hepatic metastasis, who was admitted to the ICU due to respiratory failure and hemodynamic instability. …”
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Adenoid-Cystic Carcinoma of Nasal Septum and Pterygo-Palatine Fossa by Santanu Dutta, Sudipta Pal, Sirshak Dutta

“…Local recurrence, distant metastasis and perineural invasion are the common clinico-pathological features of this tumour. …”
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PPARγ as a Novel Therapeutic Target in Lung Cancer by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…Besides having prodifferentiation, antiproliferative, and proapoptotic effects, PPARγ agonists have been shown to prevent cancer cells from acquiring the migratory and invasive capabilities essential for successful metastasis. Angiogenesis and secretion of certain matrix metalloproteinases and extracellular matrix proteins within the tumor microenvironment are also regulated by PPARγ. …”
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CircRNAs as Possible Potential Biomarkers for Breast Cancer Prognosis and Chemotherapy Response: A Comprehensive Study by Saba Mirzaei, Mahdieh Salimi, Hossein Mozdarani

“…These alterations have been related to advanced stages, lymph node involvement, and metastasis. CircRNA-000284 expression considerably decreased after chemotherapy. …”
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Correlation between Ferroptosis-Related Gene Signature and Immune Landscape, Prognosis in Breast Cancer by Jiahao Zhu, Qingqing Chen, Ke Gu, You Meng, Shengjun Ji, Yutian Zhao, Bo Yang

“…The expressions of the six FRGs were verified with real-time quantitative polymerase chain reaction and immunohistochemistry in the Human Protein Atlas. Relapse or metastasis was more likely in the high-risk group. Risk score was an independent predictor of disease-free survival. …”
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A Rare Association of Autoimmune Hemolytic Anemia with Gastric Adenocarcinoma by Kavita Agrawal, Flores Alfonso

“…Surgery was deferred primarily due to metastasis of cancer. Initially, hemoglobin was stabilized by intravenous methylprednisolone, high dose immunoglobulins, and packed red blood cell transfusions. …”
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Immediate Surgery Might Be a Better Option for Subcapsular Thyroid Microcarcinomas by Jun Jiang, Hui Lu

“…Subcapsular thyroid microcarcinomas (STMs) and nonsubcapsular thyroid microcarcinomas (NSTMs), distinguished by ultrasound, were compared in terms of tumour size, extrathyroidal extension, cervical lymph node metastasis, and multifocality. The preoperative ultrasound features predictive of recurrent laryngeal nerve (RLN) involvement were assessed. …”
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Advancing pancreatic cancer research and therapeutics: the transformative role of organoid technology by Jihao Xu, Minh Duc Pham, Vincenzo Corbo, Mariano Ponz-Sarvise, Tobiloba Oni, Daniel Öhlund, Chang-Il Hwang

“…We explore the applications of pancreatic organoids in dissecting the tumor microenvironment (TME); elucidating cancer progression, metastasis, and drug resistance mechanisms; and personalizing therapeutic strategies. …”
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Prognostic Impact of DNA-Image-Cytometry in Neuroendocrine (Carcinoid) Tumours by H. Raatz, A. Böcking, S. Hauptmann

“…Morphometric parameters like the form factor and the mean nuclear area were relevant for survival, tumour recurrence and metastasis. However, in the multivariate analysis the only independent risk factor was the histological differentiation. …”
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Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis by Bernard Friedenson

“…Breakpoint distributions in breast and EBV-associated cancers on some chromosomes were not confidently distinguished (P ConclusionsEBV infection predisposes one to breast cancer and metastasis, even if the virus disappears. Identifying this pathogenic viral damage may improve screening, treatment, and prevention. …”
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Stereotactic Body Radiotherapy for Localized Ureter Transitional Cell Carcinoma: Three Case Reports by Yoshiyasu Maehata, Kengo Kuriyama, Shinichi Aoki, Masayuki Araya, Kan Marino, Hiroshi Onishi

“…Two out of the three patients did not develop local recurrence or distant metastasis during the observation period. However, recurrence was detected in the bladder of one patient 22 months after the treatment. …”
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Advancements in the Application of Convolutional Neural Networks in Ultrasound Imaging for Breast Cancer Diagnosis and Treatment by An Zichen, Li Fan

“…It summarizes the use of DL models in breast cancer screening and in preoperative prediction of molecular subtypes, response to neoadjuvant chemotherapy (NAC), and axillary lymph node (ALN) metastasis status. The review also identifies the data limitations of using CNN models in breast US and describes the development history and current applications of DL in breast cancer screening, diagnostic guidance, and prognostic prediction. …”
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Clinicopathological importance of immunohistochemical expression of OCT4, c-MYC and Ki-67 in colorectal cancer by Rabia Hursitoglu, Abdulkadir Yasir Bahar, Sezen Koçarslan, Gökmen Aktaş, Neslihan Kurtul, Emine Kılınç

“…Cancer stem cells (CSCs) are cancer cells responsible for cancer initiation, growth, metastasis, recurrence and resistance to treatment. …”
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Metastatic Malignant Melanoma of the Inguinal Lymph Node with Unknown Primary Lesion by Sherif Ali Eltawansy, Ryane Panasiti, Samaa Hasanien, Dennis Lourdusamy, David Sharon

“…Malignant melanoma could present with metastasis with unknown primary (MUP) and this happens in 2-3% according to the studies. …”
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Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor by Georgios Androutsopoulos, Emmanouil Terzakis, Georgia Ioannidou, Athanasios Tsamandas, Georgios Decavalas

“…Follow up 5 months after initial diagnosis revealed no evidence of local recurrence or distant metastasis. The prognosis of vaginal primary malignant melanoma is very poor despite treatment modality, because most of the cases are diagnosed at advanced stage. …”
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