Clinicopathological Features and Increased Expression of Toll-Like Receptor 4 of Gastric Cardia Cancer in a High-Risk Chinese Population by Guangcan Chen, Muming Xu, Jingyao Chen, Liangli Hong, Wenting Lin, Shukun Zhao, Guohong Zhang, Guo Dan, Shuhui Liu

“…Survival was shorter with lymph node metastasis. We found a statistically significant trend for progressive increase of TLR4 expression from normal mucosa to inflammation in GCC. …”
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Hormonal-Receptors-Positive and HER2-Negative Patients with Metastatic Breast Cancer Treated with First-Line Palbociclib and Hormonal Therapy: Impact of First-Cycle Neutropenia and... by Khaled Abd Elaziz Ahmed Elnaghi, Hosam Ali Alghanmi, Shereef Ahmed Elsamany, Fathia Almarzoki, Mohamed Elsafty, Mohammad Jaffal

“…Only the Allred score and having a single site of metastasis had an independent significant relation with PFS. …”
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Uncarboxylated osteocalcin induced miR-143-3p targets SP7 and activates PI3K/Akt signaling in TNBC cells to promote invasion and migration by Qian Du, Jiaojiao Xu, Miao Zhang, Jianhong Yang

“…Patients often have elevated mortality and recurrence rates, along with a pronounced risk of distant metastasis. Our earlier research highlighted the role of uncarboxylated osteocalcin (GluOC) in fueling TNBC cell proliferation and metastasis; however the molecular underpinnings of its impact on cancer invasion and migration remain enigmatic. …”
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Novel Circulating Tumour Cell-Related Risk Model Indicates Prognosis and Immune Infiltration in Lung Adenocarcinoma by Lu Liang, Yueying Liu, Shiyao Jiang, Jingjing Huang, Hua He, Li Shen, Li Cong, Yiqun Jiang

“…LUAD has a low survival rate owing to tumour invasion and metastasis. Circulating tumour cells (CTCs) are precursors of distant metastasis, which are considered to adopt the characteristics of cancer stem cells (CSCs). …”
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EUS-FNA Diagnosis with Core Biopsy of Pancreatic Metastases from Primary Breast Cancer by Samuel Galante Romanini, Juan Pablo Román Serrano, Juliana Silveira Lima de Castro, Isabela Trindade Torres, Alex Ingold, André Lucchiari Borini, Luiz Augusto Sanches Zulske, Maria Bruna Feitosa Matias, Jéssica Said de Marchi, José Andrés Sanchez Pulla, José Celso Ardengh

“…The pancreas as a site of metastasis of other primary tumors is a rare event. …”
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Prognostic Value of Metastatic No.8p LNs in Patients with Gastric Cancer by Dong-Jiao Guo, Kun Yang, Wei-Han Zhang, Xiao-Long Chen, Xin-Zu Chen, Bo Zhang, Zong-Guang Zhou, Jian-Kun Hu

“…Patients with other distant metastasis or not in No.8p+ group had similar cumulative survival rates (24% versus 28%, P=0.914). …”
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High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer by Lin Qin, Kai Sun, Li Shi, Yushan Xu, Rongping Zhang

“…Additional hyperlipidemia promoted pancreatic carcinoma metastasis in the lung in mice injected through the tail vein, which confirmed that hyperlipidemia accelerated the process of EMT by increasing the expression of ENO1, ENO2, and ENO3, therefore promoting the pancreatic cancer cell metastasis.…”
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Progression of an Invasive ACTH Pituitary Macroadenoma with Cushing’s Disease to Pituitary Carcinoma by Clarissa Groberio Borba, Rafael Loch Batista, Nina Rosa de Castro Musolino, Vanielle Carvalho Machado, Ana Elisa Evangelista Alcantara, Gilberto Ochman da Silva, Valter Angelo Sperling Cescato, Malebranche Berardo Carneiro da Cunha Neto

“…The difficulty of defining markers for the diagnosis of carcinoma, before metastasis diagnosis, in order to change the management of the disease, is a challenge.…”
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Multimodal treatment with Neoadjuvant chemotherapy for eyelid and periocular sebaceous gland carcinoma: Long-term outcomes by Vijitha S. Vempuluru, Anshika Luthra, Vijay Anand Reddy Palkonda, Swathi Kaliki

“…No events of tumor recurrence, metastasis, or death were noted. Conclusions and importance: The long-term outcomes in patients with eyelid and periocular SGC who achieve tumor control with platinum-based NACT seem promising.…”
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Metastatic Breast Cancer to the Gastrointestinal Tract: Report of Five Cases and Review of the Literature by Massimo Ambroggi, Elisa Maria Stroppa, Patrizia Mordenti, Claudia Biasini, Adriano Zangrandi, Emanuele Michieletti, Elena Belloni, Luigi Cavanna

“…Reviewing the literature, 206 patients affected by gastrointestinal metastasis from breast cancer were identified: the most frequent site of metastasis was the stomach (60%). …”
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Sorafenib-Loaded Silica-Containing Redox Nanoparticle Decreases Tumorigenic Potential of Lewis Lung Carcinoma by Babita Shashni, Hao Thi Tran, Long Binh Vong, Ren-Jei Chung, Yukio Nagasaki

“…Survival rates in the experimental metastasis model were 66–74% for sorafenib but reached 100% for sora@siRNP, highlighting its superior efficacy and safety. …”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…EMT is closely related to the invasion and metastasis of tumour cells. The MYH9 gene is closely associated with tumour progression. …”
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Clinicopathological and Immunohistochemical Characterisation of Gastric Schwannomas in 29 Cases by Lijun Zheng, Xiaojiang Wu, Martin E. Kreis, Zhen Yu, Lijin Feng, Chunqiu Chen, Bin Xu, Zhaode Bu, Ziyu Li, Jiafu Ji

“…A significant difference was observed between the group of benign and malignant schwannomas as regards recurrences and metastasis after complete resection (P=0.015). The survival time of patients with benign schwannomas was longer than the malignant group (P=0.013), so gastric malignant schwannomas have a potential for recurrence and metastasis, with subsequently short survival. …”
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CHST1 as a prognostic-related biomarker in gastric cancer correlating with immune infiltration by Long Gui, Jin-hao Yu, Jia-nan Tan, Guang-yu Zhong, Yong-xue Wang, Lin Zhong, Jiao-jiao Su, Dong Hou, Bin Yang, Fang-hai Han, Sheng-ning Zhou

“…Overall, CHST1 may serve as a promising prognostic biomarker for GC, as it is linked to immune infiltration and facilitates GC cell proliferation and metastasis.…”
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Plasma CXCL3 Levels Are Associated with Tumor Progression and an Unfavorable Colorectal Cancer Prognosis by Can Cui, Rui Zhang, Feng Gu, Yunfeng Pei, Li Sun, Yueyang Huang, Guoping Niu, Jian Li

“…Plasma CXCL3 was also related to tumor size (P=0.034), staging (P<0.001), tumor stage (P=0.003), differentiation (P=0.001), and lymph node metastasis (P=0.007), but not to sex (P=0.853), age (P=0.691), tumor site (P=1.347), or distant metastasis (P=1.218). …”
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A new effLuc/Kate dual reporter allele for tumor imaging in mice by Latifa Bakiri, Mélanie Tichet, Carolina Marques, Martin K. Thomsen, Elizabeth A. Allen, Stefanie Stolzlechner, Ke Cheng, Kazuhiko Matsuoka, Massimo Squatrito, Douglas Hanahan, Erwin F. Wagner

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Nasopharyngeal Carcinoma: Connecting Antemortem and Postmortem Findings to Highlight a Rare Case of EBV and HPV Negativity by Thomas Auen, Geoffrey Talmon

“…Here, we discuss a nasopharyngeal carcinoma suspected as based on imaging results with metastasis to the lymph nodes, lung, spleen, bone, and liver. …”
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The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches by Xin Xing, Yongrui Bai, Jian Song

“…In this review, we discussed emerging research on the interaction between neutrophil recruitment and tumor metastasis, which is essential for studying tumor cell invasion and related immunotherapy.…”
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Anesthetic management of a patient posted for ruptured aneurysm repair with asymptomatic atrial myxoma by Priyanka Singh

“…It has to be surgically resected early when diagnosed, due to possible complications such as intracardiac obstruction, embolus, and metastasis. It becomes more challenging when found as an incidental finding in routine evaluation for a case of a ruptured aneurysm. …”
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Surgical treatment of cardiac metastatic melanoma by Robert Kwinta, Katarzyna Kopcik

“…It has a predisposition to metastasis and it presents the highest propensity to spread to the heart, mostly through the hematologic route. …”
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