The Role of Vascular Endothelial Growth Factor in Metastatic Prostate Cancer to the Skeleton by Emma Roberts, Davina A. F. Cossigny, Gerald M. Y. Quan

“…Despite the clinical implication and high incidence of bone and spinal metastases, the molecular mechanisms behind prostate cancer metastasis to bone and spine are not well understood. …”
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Patterns of failure and prognosis in nasopharyngeal carcinoma according to Epstein-Barr virus DNA status by Lin-Feng Guo, Guan-Zhong Lu, Zhen-Zhen Lu, Yi-Feng Yu, San-Gang Wu

“…Methods We included NPC patients who were diagnosed with locoregional recurrence (LRR) and/(or) distant metastasis (DM) between January 2017 and June 2024. …”
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Radical Surgery of Only the Anterior Elements of the Spine at the Posterior Element Fusion Level due to Metastatic Thyroid Cancer by Ryuto Tsuchiya, Kazuki Fujimoto, Kazuhide Inage, Sumihisa Orita, Yasuhiro Shiga, Hiroto Kamoda, Kazuyo Yamauchi, Miyako Suzuki, Jun Sato, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Masao Koda, Takeo Furuya, Junichi Nakamura, Kazuhisa Takahashi, Seiji Ohtori

“…Spinal metastasis of differentiated thyroid cancer can have a favorable prognosis if radical surgery is performed. …”
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Primary Neuroendocrine Carcinoma of Ocular Adnexa by Daisuke Yamanouchi, Toshiyuki Oshitari, Yosuke Nakamura, Jiro Yotsukura, Kaoru Asanagi, Takayuki Baba, Tomohiro Nizawa, Takashi Kishimoto, Yoko Yonemori, Satoshi Ota, Shuichi Yamamoto

“…After surgery, he underwent 50 Gy radiotherapy on the neck to prevent metastasis. No recurrence or metastasis was found for two years. …”
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Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients by Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif

“…However, no significant association was detected with tumor site, presence of lymph node spread, distant metastasis, tumor necrosis, local recurrence and alpha-fetoprotein level. …”
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Clinicopathological Characteristics and Prognosis of Upper Gastric Cancer Patients in China: A 32-Year Single-Center Retrospective Clinical Study by Yingbo Gong, Pengliang Wang, Zhi Zhu, Junyan Zhang, Jinyu Huang, Huimian Xu

“…Sex (p=0.036), tumor diameter (p=0.001), macroscopic type (p<0.001), pTM stage (p<0.001), tissue differentiation type (p=0.003), and serosal invasion (p=0.034) were independently associated with lymph node metastasis. The macroscopic type (p=0.045), lymphovascular tumor emboli (p=0.021), and pTNM stage were independently associated with recurrence and metastasis. …”
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Kindlin-1 promotes gastric cancer cell motility through the Wnt/β-catenin signaling pathway by Jun-Ho Jang, Jiyoon Jung, Hyeon-Gu Kang, Woong Kim, Won-Jin Kim, Hana Lee, Ju Yeon Cho, Ran Hong, Jeong Won Kim, Joon-Yong Chung, Kyung-Hee Chun, Seok-Jun Kim

“…Abstract Despite advances in gastric cancer diagnosis and treatment, its prognosis remains poor owing to aggressive tumor progression and metastasis. As understanding the relevant molecular mechanisms is essential to effectively improve patient outcomes, we elucidated the role of Kindlin-1 in gastric cancer progression and metastasis. …”
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Low Serum miR-607 Level as a Potential Diagnostic and Prognostic Biomarker in Patients of Pancreatic Ductal Adenocarcinoma: A Preliminary Study by Dawei Jiang, Xiangfei Yuan, Jianqi Ni, Lan Shen, Min Cai, Liu Xu

“…The miR-607 level was found to be closely correlated with lymphatic metastasis and liver metastasis, perineural invasion, and OS and PFS, and the low miR-607 level was an independent prognostic factor for the poor OS of PDAC patients. …”
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Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

“…They exhibit promising outcomes in reducing metastasis, promoting apoptosis, and inhibiting tumor invasion and progression. …”
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PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition by Hui Xiao, Longxiao Zhang, Yuan Chen, Chengjun Zhou, Xiao Wang, Dehai Wang, Zhenzhong Liu

“…Furthermore, overexpression of PKM2 can promote EMT to encourage tumor metastasis. These findings indicate PKM2 is a potentially useful diagnostic biomarker and therapeutic target in breast cancer.…”
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Synergistic effect of blocking cancer cell invasionrevealed by computer simulations by Kazuhisa Ichikawa

“…Invasion and metastasis are the main cause of death in cancer patients. …”
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The Role of the TGF-β Coreceptor Endoglin in Cancer by Eduardo Pérez-Gómez, Gaelle del Castillo, Juan Francisco Santibáñez, Jose Miguel Lêpez-Novoa, Carmelo Bernabéu, Miguel Quintanilla

“…In addition, recent studies on human and experimental models of carcinogenesis point to an important tumor cell–autonomous role of endoglin by regulating proliferation, migration, invasion, and metastasis. These studies suggest that endoglin behaves as a suppressor of malignancy in experimental and human epithelial carcinogenesis, although it can also promote metastasis in other types of cancer. …”
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Correlation between Clinicopathology and Expression of Heat Shock Protein 72 and Glycoprotein 96 in Human Esophageal Squamous Cell Carcinoma by Xiaoping Wang, Qiaoxia Wang, Huanping Lin

“…HSP72 and gp96 expression were significantly associated with the presence of tumor infiltration, lymph node, and remote metastasis.…”
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Refractory Thrombocytopenia Responds to Octreotide Treatment in a Case of Evans Syndrome with Gastric Neuroendocrine Tumor by Kocfa Chung-Delgado, Alejandro Revilla-Montag, Sonia Guillén-Bravo, Hugo Ríos-Díaz, José C. Alva-Muñoz

“…Weeks later, the hepatic metastasis is discarded by a negative octreotide-body scan, and the octreotide treatment was interrupted. …”
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Orbital ameloblastoma: research and challenges of a rare benign tumor by Rui Zhang, Xiaoming Huang, Fengyuan Sun, Tong Wu

“…According to world literature reports, there are 32 cases of maxillary bone metastasis to the orbit and 4 cases of mandibular bone metastasis to the orbit. …”
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Serum High-Density Lipoprotein Cholesterol Concentrations in Pancreatic Ductal Adenocarcinoma and Its Association With Histological Grade in a Chinese Population by Ying-Ying Cao PhD, Xiao-Jing Lv MD, Hui Li PhD, Li-Chao Qian PhD, Hai-Peng Si MD, Yuan Li PhD, Kai Guo PhD, Shuai Ren PhD, Zhong-Qiu Wang MD

“…Moreover, HDL-c levels were inversely related to lymph node metastasis in the training ( P = 0.001) and validation ( P = 0.012) sets. …”
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Metastatic Periampullary Tumor from Hepatocellular Carcinoma Presenting as Gastrointestinal Bleeding by Amir Kashani, Nicholas N. Nissen, Maha Guindi, Laith H. Jamil

“…Metastasis of HCC to the gastrointestinal (GI) tract should be considered as a cause of GI bleeding.…”
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Female urethral diverticular carcinoma: a case report and review of the literature by Dan Li, Fan Hua Meng, Xu Yang

“…For female patients with urethral diverticulum cancer without distant metastasis, surgery remains the primary treatment. For patients with distant metastasis, a combination of surgery, chemotherapy, and radiotherapy may be considered.Genetic testing and targeted immunotherapy offer new approaches for future treatment.…”
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Anticancer effect of curcumin on breast cancer and stem cells by Hui-Tien Liu, Yuan-Soon Ho

“…Numerous studies have shown that curcumin, a natural compound, exerts anticancer effects by inhibiting cancer cell proliferation and metastasis and by inducing cell cycle arrest and apoptosis. …”
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Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

“…They exhibit promising outcomes in reducing metastasis, promoting apoptosis, and inhibiting tumor invasion and progression. …”
Get full text