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A molecular basis for spine color morphs in the sea urchin Lytechinus variegatus
Published 2024-11-01“…Through genetic crosses we learned that white is dominant over red and green colors, and that pigmentation follows classic Mendelian genetics. The abundance of mRNAs encoding flavin mono-oxygenase variancts and polyketide synthase was predictive of the color of the adult and antibodies identified their histological location in the spine cells. …”
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Strains of Rodents and the Pharmacology of Learning and Memory
Published 2004-01-01“…Mendelian genetic tools have extensively been used to improve the description of the pharmacological mechanisms involved in learning and memory. …”
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Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease
Published 2024-11-01“…Within this group, an increasing number of families have been identified, where Mendelian genetic disorders implicate defective mitochondrial RNA biology. …”
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GENETIC CONTROL OF MORPHOLOGICAL CHARACTERS OF SEEDLINGS, BOLLS, AND SEEDS IN FLAX (LINUM USITATISSIMUM L.)
Published 2014-12-01“…The inheritance of 14 genes has been studied by Mendelian genetic analysis. Five genes of six influencing hypocotyl color exert pleiotropic effects on other morphological characters: s1, yellow or green (s1-2) seeds, star-shaped white flower, and yellow anthers; sfbs1, white corolla of poorly pronounced star shape and yellow anthers; pbc3, star-shaped blue-tinged white flower and orange anthers; pbc1, blue-tinged white corrugated corolla and yellow anthers; f e, spotted seeds, pale blue corolla, and gray anthers. …”
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Treatment of Cancer Gene Changes in Chronic Myeloid Leukemia by Big Data Analysis Platform-Based Dasatinib
Published 2022-01-01“…An integrated gene expression analysis system (IEAS) was firstly constructed to automatically classify data in the online human Mendelian genetic database using clustering algorithms. …”
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Fetal medicine and current practice of prenatal screening
Published 2023-01-01“…The option for preimplantation genetic diagnosis (PGD) offers primary prevention by specific wild embryo selection and implantation in an in vitro fertilization cycle, following exclusion of affected embryo for aneuploidy (PGD-A), structural chromosome aberration (PGD-A), and a monogenic Mendelian genetic disease (PGD-M). The prenatal screening or diagnosis by the Fetal Medicine Team remains the mainstay for identification and management of pregnancies at high risk of genetic disorders.…”
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