Showing 6,841 - 6,860 results of 7,360 for search '"Medicine"', query time: 0.09s Refine Results
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    Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer by Angelica Nogueira Rodrigues, Andreza Karine de Barros Almeida Souto, Diocésio Alves Pinto de Andrade, Larissa Müller Gomes, Sandra Satie Koide, Renata de Godoy e Silva, Bruno Batista de Souza, Juliana Doblas Massaro, Andréia Cristina de Melo, Andrea Morais Borges, Camila Giro, Carlos Augusto Vasconcelos de Andrade, Cesar Martins da Costa, Daniel Luiz Gimenes, Eduardo Caminha Bandeira de Mello, Fernanda Cesar de Oliveira, Frederico Müller de Toledo Lima, Gabriel Lima Lopes, Gustavo de Oliveira Bretas, Gustavo Guerra Jacob, Herika Lucia da Costa Silva, Juliana Ferrari Notaro, Lara Ladislau Alves, Marcos Veloso Moitinho, Mirian Cristina da Silva, Roberto Abramoff, Thais Amaral da Cunha Rauber, Rodrigo Dienstmann, Fernanda Christtanini Koyama

    Published 2025-02-01
    “…In this scenario, access to a validated diagnostic HRD test can optimize treatment selection and increase the effectiveness of the intervention.ObjectiveTo technically validate an in-house next-generation sequencing (NGS)-based HRD test, QIAseq Custom Panel (QIAGEN), by comparing it with the reference assay, MyChoice CDx® Plus HRD (Myriad Genetics), which is used in routine care.MethodsThis is a prospective cohort study conducted at the Oncoclínicas Precision Medicine (OCPM) laboratory using samples from patients with advanced or relapsed platinum-sensitive ovarian cancer eligible for HRD testing in a diagnostic clinical setting at Oncoclínicas and Co. …”
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    Comparison of effectiveness in smoking cessation using nicotine replacement therapy and electronic cigarettes by Adrianna Kopaczyńska, Katarzyna Szafrańska, Szymon Niemirka, Aleksandra Janiak, Kinga Dominiczak, Łukasz Grądalski, Filip Dębicki

    Published 2025-02-01
    “…The impact of electronic cigarettes on smoking cessation also remains controversial, taking into consideration how little today's medicine does know about the long-term side effects of using e-cigarettes. …”
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    Outcomes and Complications of Minimally Invasive Glaucoma Surgeries (MIGS) in Primary Angle Closure and Primary Angle Closure Glaucoma: A Systematic Review and Meta-Analysis by Paik B, Chua CH, Yip LW, Yip VC

    Published 2025-02-01
    “…Benjamin Paik,1 Chun Hau Chua,2 Leonard W Yip,1,2 Vivien CH Yip1,2 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 2Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, SingaporeCorrespondence: Vivien CH Yip, TTSH Medical Centre, 11 Jalan Tan Tock Seng, Level 1, Singapore, 308433, Singapore, Email vyip82@yahoo.co.ukTopic: To analyse the safety and efficacy of minimally invasive glaucoma surgeries (MIGS) in lowering IOP and medication burden in primary angle closure (PAC) or primary angle closure glaucoma (PACG).Clinical Relevance: MIGS is off-label in angle closure, as implantation of the device is difficult when there is iridotrabecular contact. …”
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