An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept studyResearch in context by Marirena Bafaloukou, Ann-Kathrin Schalkamp, Nan Fletcher-Lloyd, Alex Capstick, Chloe Walsh, Cynthia Sandor, Samaneh Kouchaki, Ramin Nilforooshan, Payam Barnaghi

“…Infrastructure support for this research was provided by the NIHR Imperial Biomedical Research Centre (BRC) and the UKRI Medical Research Council (MRC). P.B. is also funded by the Great Ormond Street Hospital and the Royal Academy of Engineering. …”
Get full text

Role of Neuron-Specific Enolase in the Diagnosis and Disease Monitoring of Sarcoidosis by Noriaki Sunaga, Yasuhiko Koga, Yoshimasa Hachisu, Koichi Yamaguchi, Masaki Aikawa, Norimitsu Kasahara, Yosuke Miura, Hiroaki Tsurumaki, Masakiyo Yatomi, Reiko Sakurai, Toshitaka Maeno, Takeshi Hisada

Get full text

Short-Term Exercise Training Improves Insulin Sensitivity but Does Not Inhibit Inflammatory Pathways in Immune Cells from Insulin-Resistant Subjects by Sara M. Reyna, Puntip Tantiwong, Eugenio Cersosimo, Ralph A. DeFronzo, Apiradee Sriwijitkamol, Nicolas Musi

Get full text

The developmental lipidome of Nippostrongylus brasiliensis by Tao Wang, Michael G. Leeming, Nicholas A. Williamson, Tiffany Bouchery, Rory Doolan, Graham Le Gros, Gavin E. Reid, Nicola L. Harris, Robin B. Gasser

Get full text

Association Between Mental Illness and Diabetes: an Expert Opinion-Based Analysis by Elizabeth Cristina Mayorga Aldaz, Roberto Javier Aguilar Berrezueta, Elizabeth Altamirano

“…<strong>Foundation:</strong> the association between mental disorders and diabetes mellitus has had growing interest in medical research and clinical practice. Understanding of the relationship between these two conditions has expanded in recent years and a bidirectional relationship between them has been recognized. …”
Get full text

Decrease of PPARδ in Type-1-Like Diabetic Rat for Higher Mortality after Spinal Cord Injury by Cheng-Chia Tsai, Kung-Shing Lee, Sheng-Hsien Chen, Li-Jen Chen, Keng-Fan Liu, Juei-Tang Cheng

Get full text

The study of the functionality of cardiomyocytes obtained from induced pluripotent stem cells for the modeling of cardiac arrhythmias based on long QT syndrome by M. M. Slotvitsky, V. A. Tsvelaya, S. R. Frolova, E. V. Dement’eva, K. I. Agladze

Get full text

How to Utilize CAT and mMRC Scores to Assess Symptom Status of Patients with COPD in Clinical Practice? by Esra ERTAN YAZAR, Elif Yelda NIKSARLIOGLU, Burcu YIGITBAS, Mesut BAYRAKTAROGLU

“…Objective: In this study, we aimed to investigate the compatibility of modified Medical Research Council (mMRC) and COPD assessment test (CAT) scores of chronic obstructive pulmonary disease (COPD) patients in terms of evaluation of their symptom status. …”
Get full text

Analysis of the effects of group progressive resistance training on inflammatory markers, cardiovascular fitness parameters, and respiratory function in elderly patients with chron... by Chunyang Li, Yijia Sun

“…Background: To investigate the effects of implementing group progressive resistance training on Maximal Oxygen consumption (VO2max), Maximum Ventilation per minute (VEmax), Maximal Oxygen pulse (O2pulsemax), Maximum Heart Rate (HRmax), and Modified Medical Research Council dyspnea scale (mMRC) in elderly patients with chronic obstructive pulmonary disease. …”
Get full text

Effect of Pulmonary Rehabilitation on Dyspnoea, Functional Capacity and Thoracic Excursion in Chronic Obstructive Pulmonary Disease: A Case Report by Priyanka K Chilhate, Lajwanti Lalwani (Adwani)

“…Before starting treatment, a baseline assessment was done, including measures like Modified Medical Research Council (mMRC) grading for breathlessness, 6-Minute Walk Distance (6MWD) and chest movement. …”
Get full text

Arterial Stiffness in Nonhypertensive Type 2 Diabetes Patients in Ghana by Kwame Yeboah, Daniel A. Antwi, Ben Gyan

Get full text

Effect of electrical stimulation with a cochlear implant on tinnitus impact: protocol of an individual patient data meta-analysis by Inge Stegeman, Adriana L Smit, Kelly Assouly

“…Second, linear regression analyses will be used to model the effect of electrical stimulation on tinnitus impact based on relevant predictors.Ethics and dissemination The Medical Research Involving Human Subject Act does not apply, and ethical approval is not required. …”
Get full text

A Systematic Review of the Clinimetric Properties of Habitual Physical Activity Measures in Young Children with a Motor Disability by Stina Oftedal, Kristie L. Bell, Louise E. Mitchell, Peter S. W. Davies, Robert S. Ware, Roslyn N. Boyd

Get full text

Proportions of Proinflammatory Monocytes Are Important Predictors of Mortality Risk in Hemodialysis Patients by Yachung Jeng, Paik Seong Lim, Ming Ying Wu, Tien-Yu Tseng, Chang Hsu Chen, Hung Ping Chen, Tsai-Kun Wu

Get full text

Cucurbitacin IIa Alleviates Colitis via Promoting the Release of Host-Derived Extracellular Vesicles Encapsulating microRNA-30b-5p by Zhao Y, Jiang B, Zuo S

“…Yinyin Zhao,1 Binyuan Jiang,2 Shengnan Zuo3 1Ningbo Institute of Innovation for Combined Medicine and Engineering (NIIME), The Affiliated LiHuiLi Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Medical Research Center of the Affiliated Changsha Central Hospital of Hengyang Medical School, University of South China, Changsha, People’s Republic of China; 3Clinical Laboratory Department, Hunan Guangxiu Hospital, Changsha, People’s Republic of ChinaCorrespondence: Binyuan Jiang; Shengnan Zuo, Email 2018050871@usc.edu.cn; shengnanzuo123@sina.comPurpose: Cucurbitacins have demonstrated anti-inflammatory effects and show promise for inflammatory bowel diseases. …”
Get full text

Abrocitinib monotherapy in Investigator’s Global Assessment nonresponders: improvement in signs and symptoms of atopic dermatitis and quality of life by Andrew Blauvelt, Mark Boguniewicz, Patrick M. Brunner, Paula C. Luna, Pinaki Biswas, Marco DiBonaventura, Saleem A. Farooqui, Ricardo Rojo, Michael C. Cameron

Get full text

Intestinal Schistosomiasis among Primary Schoolchildren in Two On-Shore Communities in Rorya District, Northwestern Tanzania: Prevalence, Intensity of Infection and Associated Risk... by David Z. Munisi, Joram Buza, Emmanuel A. Mpolya, Safari M. Kinung’hi

Get full text

Documenting and Reporting Implementation Strategies of Vaccination Efforts (DRIVE) framework for fostering systems learning to enhance cross-context replication in immunization pro... by Abdu A. Adamu, Amos Petu, Balcha G. Masresha, Blaise Bathondoli, Rabiu Ibrahim Jalo, Duduzile Ndwandwe, Charles S. Wiysonge

Get full text

Strengthening teamwork and respect (STAR) in maternity units: developing a health system intervention in South Africa by Tanya Doherty, Ruwayda Petrus, Sandra Land, Christiane Horwood, Veronique Filippi, Lyn Haskins, Cleo Phewa, Sphindile Mapumulo, Silondile Luthuli, Vaughn M. John

Get full text

Emerging Norovirus GII.12 infection in 2010 in Northern Taiwan by Chi-Neu Tsai, Yu-Chung Chang, Hsun-Ching Chao, Yi-Hsiang Hsu, Yuan-Hung Wang, Shih-Yen Chen

Get full text