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An Injectable Hydrogel Bioimplant Loaded with Engineered Exosomes and Triple Anti-Tuberculosis Drugs with Potential for Treating Bone and Joint Tuberculosis
Published 2025-01-01“…Jiayan Huang,1,* Han Li,2,* Yuting Mei,1 Pengcheng Yi,1 Yunyao Ren,1 Yunjuan Wang,3 Limei Han,1 Qiusha Tang,3 Dongfang Liu,3 Wei Chen,4 Yanli An,5 Chunmei Hu1 1Department of Tuberculosis, the Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Department of Pharmacy, Central Hospital of Guangdong Provincial Nongken, Zhanjiang, Guangdong, People’s Republic of China; 3Medical School of Southeast University, Nanjing, People’s Republic of China; 4Department of Clinical Research Center, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 5Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Center of Interventional Radiology & Vascular Surgery, Department of Radiology, Medical School, Zhong da Hospital, Southeast University, Nanjing, Jiangsu People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunmei Hu, Department of Tuberculosis, the Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Zhongfu Road 1-1, Yijiangmen Street, Nanjing, Jiangsu Province, 210009, People’s Republic of China, Email njyy003@njucm.edu.cnPurpose: Treatment for bone and joint tuberculosis (BJTB) is challenging due to its refractory and recurrent nature. …”
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