Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

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Investigating the role of cathepsins in breast cancer progression: a Mendelian randomization study by Shengyi Zhou, Shengyi Zhou, Shengyi Zhou, Yizhou Sun, Yizhou Sun, Wenzhang Zha, Wenzhang Zha, Guangjun Zhou, Guangjun Zhou

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Systemic Inflammatory Effects of Traumatic Brain Injury, Femur Fracture, and Shock: An Experimental Murine Polytrauma Model by C. Probst, M. J. Mirzayan, P. Mommsen, C. Zeckey, T. Tegeder, L. Geerken, M. Maegele, A. Samii, M. van Griensven

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Perioperative nursing of an osteoporosis patient undergoing second operation for Stanford type A aortic dissection (合并骨质疏松的Stanford A型主动脉夹层二次手术患者的围术期护理)... by JIN Fangfang (金芳芳), SU Yunyan (苏云艳), HU Yuexiu (胡岳秀), WU Mengya (伍梦雅)

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Operationalizing goal setting as an outcome measure in trials involving patients with frailty, multimorbidity or complexity by Emma Tenison, Katherine Lloyd, Yoav Ben-Shlomo, Emily J. Henderson

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Reverse mutational scanning of SARS-CoV-2 spike BA.2.86 identifies epitopes contributing to immune escape from polyclonal sera by Najat Bdeir, Tatjana Lüddecke, Henrike Maaß, Stefan Schmelz, Ulfert Rand, Henning Jacobsen, Kristin Metzdorf, Upasana Kulkarni, Anne Cossmann, Metodi V. Stankov, Markus Hoffmann, Stefan Pöhlmann, Wulf Blankenfeldt, Alexandra Dopfer-Jablonka, Georg M. N. Behrens, Luka Čičin-Šain

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A genome-wide association study identifies genetic variants associated with hip pain in the UK Biobank cohort (N = 221,127) by Qi Pan, Yiwen Tao, Tengda Cai, Abi Veluchamy, Harry L. Hebert, Peixi Zhu, Mainul Haque, Tania Dottorini, Lesley A. Colvin, Blair H. Smith, Weihua Meng

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Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection by Trever T. Greene, Yeara Jo, Carolina Chiale, Monica Macal, Ziyan Fang, Fawziyah S. Khatri, Alicia L. Codrington, Katelynn R. Kazane, Elizabeth Akbulut, Shobha Swaminathan, Yu Fujita, Patricia Fitzgerald-Bocarsly, Thekla Cordes, Christian Metallo, David A. Scott, Elina I. Zúñiga

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Nanocomposite magnetic hydrogel with dual anisotropic properties induces osteogenesis through the NOTCH-dependent pathways by Shijia Tang, Yue Yan, Xiaoli Lu, Peng Wang, Xueqin Xu, Ke Hu, Sen Yan, Zhaobin Guo, Xiao Han, Feimin Zhang, Ning Gu

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“I’m living in a ‘no’ world now…”- A qualitative study of the widespread impact of living with chronic breathlessness, and experiences of identification and assessment of this symp... by Helene L. Elliott-Button, Miriam J. Johnson, Ann Hutchinson, David C. Currow, Joseph Clark

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Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) by Daisy Gaunt, Chris Salisbury, Mei-See Man, Katherine Chaplin, Polly Duncan, Mairead Murphy

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Intra-Articular Application of Sluijter-Teixera Poisson Pulsed Radiofrequency in Symptomatic Patients with Knee Osteoarthritis: Focus upon Clinical Efficacy and Safety by D. Filippiadis, A. Tsochatzis, E. Petsatodis, S. Galanis, G. Velonakis, C. Giankoulof, A. Kelekis

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Association between deep gray matter iron deposition and clinical symptoms in Parkinson’s disease: a quantitative susceptibility mapping study by Hui Zhao, Hui Zhao, Qiu-Hong Ji, Zhong-Zheng Jia, Li-Hua Shen

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Childhood neurodivergent traits, inflammation and chronic disabling fatigue in adolescence: a longitudinal case–control study by Neil A Harrison, Hugo D Critchley, Jessica Eccles, Kevin A Davies, Lisa Quadt, Rod Bond, Jenny Csecs

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Comprehensive Analysis of the Mechanism of Anoikis in Hepatocellular Carcinoma by Dongqian Li, Qian Bao, Shiqi Ren, Haoxiang Ding, Chengfeng Guo, Kai Gao, Jian Wan, Yao Wang, MingYan Zhu, Yicheng Xiong

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Norepinephrine Infusion and the Central Venous Waveform in a Porcine Model of Endotoxemic Hypotension with Resuscitation: A Large Animal Study by Zachary R. Bergman, Roy K. Kiberenge, Richard W. Bianco, Gregory J. Beilman, Colleen M. Brophy, Kyle M. Hocking, Bret D. Alvis, Eric S. Wise

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Molecular profiling of frontal and occipital subcortical white matter hyperintensities in Alzheimer’s disease by Sulochan Malla, Sulochan Malla, Annie G. Bryant, Annie G. Bryant, Rojashree Jayakumar, Benjamin Woost, Nina Wolf, Andrew Li, Sudeshna Das, Sudeshna Das, Susanne J. van Veluw, Susanne J. van Veluw, Rachel E. Bennett, Rachel E. Bennett

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Intraperitoneal Injection of Multiplacentas Pooled Cells Treatment on a Mouse Model with Aplastic Anemia by Jun Li, Hong Chen, Yan-Bo Lv, Qiang Wang, Zheng-Jun Xie, Li-Hua Ma, Jie He, Wei Xue, Shan Yu, Jun Guo, Ting-Hua Wang, Tian-Xi Wu, Xing-Hua Pan

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You cannot be what you cannot see: a retrospective natural longitudinal cohort study exploring the impact of face-to-face rural immersion on student medical training satisfaction a... by Srinivas Kondalsamy-Chennakesavan, Matthew R McGrail, Bushra F Nasir, Alan Bruce Chater

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Comparative Efficacy and Safety of Cardio-Renoprotective Pharmacological Interventions in Chronic Kidney Disease: An Umbrella Review of Network Meta-Analyses and a Multicriteria De... by Ioannis Bellos, Smaragdi Marinaki, Pagona Lagiou, Vassiliki Benetou

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