Accelerated symptom improvement in Parkinson’s disease via remote internet-based optimization of deep brain stimulation therapy: a randomized controlled multicenter trial by Alireza Gharabaghi, Sergiu Groppa, Marta Navas-Garcia, Alfons Schnitzler, Laura Muñoz-Delgado, Vicky L. Marshall, Jessica Karl, Lin Zhang, Ramiro Alvarez, Mary S. Feldman, Michael J. Soileau, Lan Luo, S. Elizabeth Zauber, Benjamin L. Walter, Chengyuan Wu, Hong Lei, Damian M. Herz, Ming-Hua Chung, Yagna Pathak, Bram Blomme, Binith Cheeran, Corneliu Luca, Daniel Weiss

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Shared prognostic information in amyotrophic lateral sclerosis – systematic assessment of the patients’ perception of neurofilament light chain and the ALS functional rating scale... by Lukas Maximilian Möhwald, André Maier, Torsten Grehl, Ute Weyen, Patrick Weydt, René Günther, Paul Lingor, Bettina Göricke, Susanne Petri, Julian Grosskreutz, Matthias Boentert, Isabell Cordts, Jochen H. Weishaupt, Johannes Dorst, Christoph Münch, Thomas Meyer, Petra Baum

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Enhancement of Doxorubicin Efficacy by Bacopaside II in Triple-Negative Breast Cancer Cells by Sima Kianpour Rad, Kenny K. L. Yeo, Runhao Li, Fangmeinuo Wu, Saifei Liu, Saeed Nourmohammadi, William M. Murphy, Yoko Tomita, Timothy J. Price, Wendy V. Ingman, Amanda R. Townsend, Eric Smith

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Advanced Fractional Mathematics, Fractional Calculus, Algorithms and Artificial Intelligence with Applications in Complex Chaotic Systems by Dumitru Baleanu, Yeliz Karaca

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The absolute number of circulating Treg cells is reduced in difficult-to-treat RA patients and is ameliorated by low-dose IL-2 by Huanhuan Yan, Huanhuan Yan, Huanhuan Yan, Xiaoyu Zi, Xiaoyu Zi, Xiaoyu Zi, Huer Yan, Xiaoying Zhang, Xiaoying Zhang, Xiaoying Zhang, Jie Bai, Jie Bai, Jie Bai, Chong Gao, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Caihong Wang, Caihong Wang, Caihong Wang

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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

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Comparison of Influence of Office and 24‐h Central Aortic Blood Pressure on Target Organ Damage in Hypertension by Yueliang Hu, Hui Yang, Guili Chang, Yaya Bai, Alberto Avolio, Qian Wang, Shenshen Gao, Junli Zuo

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Performance of the modified 2022 ACR/EULAR giant cell arteritis classification criteria without age restriction for discriminating from Takayasu arteritis by Takahiko Sugihara, Masayoshi Harigai, Haruhito A. Uchida, Hajime Yoshifuji, Yasuhiro Maejima, Jun Ishizaki, Yoshiko Watanabe, Hiroaki Dobashi, Yoshinori Komagata, Naoto Tamura, Yoshikazu Nakaoka, Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS)

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Intracranial aneurysm instability prediction model based on 4D-Flow MRI and HR-MRI by Fei Peng, Jiaxiang Xia, Fandong Zhang, Shiyu Lu, Hao Wang, Jiashu Li, Xinmin Liu, Yao Zhong, Jiahuan Guo, Yonghong Duan, Binbin Sui, Chuyang Ye, Yi Ju, Shuai Kang, Yizhou Yu, Xin Feng, Xingquan Zhao, Rui Li, Aihua Liu

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Impact of Obesity on Short-Term Outcomes in Patients Undergoing Retroperitoneal Laparoscopic/Retroperitoneoscopic Adrenalectomy for Benign or Malignant Adrenal Diseases: A Meta-Ana... by Maurizio Zizzo, Andrea Morini, Magda Zanelli, Chiara Grasselli, Francesca Sanguedolce, Sze Ling Wong, Munyaradzi G. Nyandoro, Andrea Palicelli, Giuseppe Broggi, Nektarios I. Koufopoulos, Lucia Mangone, Angelo Cormio, Rosario Caltabiano, Antonino Neri, Massimiliano Fabozzi

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Iterative delivery of an implementation support package to increase and sustain the routine provision of antenatal care addressing alcohol consumption during pregnancy: study proto... by John Attia, Luke Wolfenden, Nicole Nathan, Melanie Kingsland, Olivia Wynne, Penny Reeves, Alix Hall, John Wiggers, Elizabeth J Elliott, Tameka McFadyen, Tracey W Tsang, Emma Doherty, Belinda Tully, Adrian John Dunlop, Ian Symonds

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Nature and prevalence of long-term conditions in people with intellectual disability: retrospective longitudinal population-based study by Ashley Akbari, Navjot Kaur, Rania Kousovista, Gemma Lewin, Emeka Abakasanga, Rishika Shivamurthy, Georgina Cosma, Gyuchan Jun, Satheesh Gangadharan

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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlle... by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

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Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective... by Jesper D. Gunst, Jesal Gohil, Johanthan Z. Li, Ronald J. Bosch, Andrea White, Catherine Seamon, Tae-Wook Chun, Beatriz Mothe, Kathleen Gittens, Lauren Praiss, Marie-Angélique De Scheerder, Linos Vandekerckhove, Kevin Escandón, Ann Thorkelson, Timothy Schacker, Devi SenGupta, Christian Brander, Emmanouil Papasavvas, Luis J. Montaner, Javier Martinez-Picado, Ruxandra Calin, Antonella Castagna, Camilla Muccini, Wesley de Jong, Lorna Leal, Felipe Garcia, Rob A. Gruters, Timothy Tipoe, John Frater, Ole S. Søgaard, Sarah Fidler

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Endothelial Activation and Stress Index (EASIX) to predict mortality after allogeneic stem cell transplantation: a prospective study by Axel Benner, Peter Dreger, Grzegorz W Basak, Christian Koenecke, Olaf Penack, Christophe Peczynski, Lucia López Corral, Ivan Moiseev, Hélène Schoemans, Zinaida Peric, Thomas Luft, Simona Sica, Mutlu Arat, Maija Itäla-Remes, Nicolaas P M Schaap, Michal Karas, Ludek Raida, Thomas Schroeder, Elisabetta Metafuni, Tulay Ozcelik, Brenda M Sandmaier, Lambros Kordelas

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Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) by Robert Chen, Angus G K McNair, Vafa Rahimi-Movaghar, Julio C Furlan, Benjamin M Davies, Oliver D Mowforth, Iwan Sadler, Bizhan Aarabi, Brian K Kwon, Michael G Fehlings, James S Harrop, Armin Curt, Ellen Sarewitz, Carl Moritz Zipser, Timothy F Boerger, Mark R N Kotter, James Milligan, Lindsay Tetreault, Danyal Khan, Keng Siang Lee, Alvaro Yanez Touzet, Ricardo Rodrigues-Pinto, James D Guest, Sukhvinder Kalsi-Ryan, Shirley Widdop

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improving Pain mAnagement for childreN and young people attendeD by Ambulance (PANDA): protocol for a realist review. [version 3; peer review: 2 approved, 1 approved with reservati... by Paul Leighton, Georgette Eaton, Georgie Nicholls, Kacper Sumera, Marishona Ortega, Jessica Hodgson, Michael Baliousis, Aloysius Niroshan Siriwardena, Despina Laparidou, Bill Lord, Sarah Redsell, Gregory Adam Whitley, Tatiana Bujor

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Oral behaviors in Chinese temporomandibular disorder patients: insights from exploratory and confirmatory factor analyses by Tiqian Liu, Tiqian Liu, Adrian Ujin Yap, Adrian Ujin Yap, Adrian Ujin Yap, Yanyu Sun, Yanyu Sun, Yunhao Zheng, Yunhao Zheng, Tianqi Wang, Tianqi Wang, Shiya Zeng, Shiya Zeng, Zhen Liu, Xin Xiong, Xin Xiong

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Restorative Neurostimulation Therapy Compared to Optimal Medical Management: A Randomized Evaluation (RESTORE) for the Treatment of Chronic Mechanical Low Back Pain due to Multifid... by Frank Schwab, Nagy Mekhail, Kiran V. Patel, Meredith Langhorst, Robert D. Heros, Jonathan Gentile, Sherif Costandi, Gregory Moore, Christopher Gilmore, Smith Manion, Krishnan Chakravarthy, S. Craig Meyer, Justin V. Bundy, Jordan L. Tate, Rebecca Sanders, Sandeep Vaid, Oszkar Szentirmai, Johnathan Goree, Vikas V. Patel, Jeff Lehmen, Mehul J. Desai, Jason E. Pope, Anthony Giuffrida, Salim Hayek, Sohrab Singh Virk, Richard Paicius, William R. Klemme, Robert Levy, Christopher Gilligan, the RESTORE investigators

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Predictors of cytomegalovirus infection in patients with connective tissue disease treated by pulsed methylprednisolone therapy: a multicenter retrospective cohort study by Haruka Ito, Takahiko Yoshimoto, Akatsuki Kokaze, Kuninobu Wakabayashi, Kazuteru Noguchi, Kiyoshi Matsui, Bunki Natsumoto, Keishi Fujio, Yutaro Hayashi, Yuko Kaneko, Takahisa Gono, Koh Okamoto, Shu Okugawa, Kyoji Moriya, Hirohiko Sueki

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