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47581
Correlation Analysis of Twig and Leaf Characteristics and Leaf Thermal Dissipation of <i>Hippophae rhamnoides</i> in the Riparian Zone of the Taohe River in Gansu Province, China
Published 2025-01-01“…The co-variation of plant branches and leaves and the timely adjustment of thermal dissipation in photoheterogeneous habitats reflect the phenotypic plasticity mechanism and self-protection strategy of riparian plants in adapting to heterogeneous environments.…”
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47582
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A
Published 2024-07-01“…A BoNT/A LC-specific antibody is capable of effectively inhibiting BoNT/A by mechanisms not previously associated with antibodies that neutralize BoNT. …”
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47583
Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation
Published 2025-02-01“…RNA-sequencing transcriptomic analyses of strains having different compositions of pseudovibriamides suggested that both pseudovibriamides A and B affect genes potentially involved in motility, and that a compensatory mechanism is at play in mutants that produce only pseudovibriamide A, resulting in comparable flagellar motility as the wild type. …”
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47584
Sustainable Development Goals and Food Remittances: COVID-19 Lockdowns, Digital Transformation, Lessons and Policy Reflections from South Africa-Zimbabwe Corridor
Published 2025-01-01“…The COVID-19 pandemic profoundly disrupted the mechanisms and pathways through which international migrants transfer food remittances to their home countries. …”
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47585
Transcriptome Analysis Reveals Key Genes Involved in the Response of <i>Triticum urartu</i> to Boron Toxicity Stress
Published 2025-01-01“…The obtained results suggest that several mechanisms are involved in regulating the response of the studied <i>T. urartu</i> genotype toward B toxicity. …”
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47586
The antiarthritic effect of CBR‐470‐1 in hypoxic environment is to increase the level of NOD‐like receptor family pyrin domain containing 3 ubiquitination by decreasing phosphoglyc...
Published 2025-01-01“…Western Blot analysis was used to explore the underlying mechanism of these experimental results. Additionally, a co‐culture system of THP‐1 and chondrocytes was established to investigate the impact of CBR‐470‐1 on chondrocyte proliferation, apoptosis, migration and the regulation of chondrocyte‐related proteins within the system. …”
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47587
Collagenase Chemonucleolysis for Treating Cervical Disc Herniation: An Exploratory, Single-Arm, Open-Label, Multicenter Clinical Trial
Published 2024-11-01“…Collagenase chemonucleolysis has been successfully applied to treat lumbar disc herniation, which has a similar pathological mechanism to CDH. However, its application for CDH remains under-researched, and there is an even greater lack of high-quality clinical evidence. …”
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47588
Differences in EEG complexity of cognitive activities among subtypes of schizophrenia
Published 2025-02-01“…IntroductionThe neural mechanisms that underpin cognitive impairments in patients with schizophrenia remain unclear. …”
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47589
LncRNA-ANRIL regulates CDKN2A to promote malignant proliferation of Kasumi-1 cells
Published 2025-01-01“…Abstract Objective This study aimed to investigate the regulatory effects of long non-coding RNA-ANRIL on CDKN2A in the cell cycle of Kasumi-1 cells and elucidate the underlying molecular mechanisms. Methods ANRIL and CDKN2A expression levels were quantified using RT-qPCR in peripheral blood samples from acute myeloid leukemia (AML) patients. …”
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47590
Search for biocontrol agents among endophytic lipopeptidesynthesizing bacteria <i>Bacillus</i> spp. to protect wheat plants against Greenbug aphid (<i>Schizaphis graminum</i>)
Published 2024-05-01“…Also, lipopeptides are able to trigger induced systemic resistance (ISR) in plants against harmful organisms, but the physiological mechanisms of their action are just beginning to be studied. …”
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47591
MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis
Published 2025-02-01“…ST was performed on skin tissue samples from mice in each group after wound healing to analyze the heterogeneity of major cell types compared with the control group and investigate potential mechanisms affecting wound healing and scar formation. …”
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47592
Correlated factors of posttraumatic growth in patients with colorectal cancer: A systematic review and meta-analysis
Published 2025-01-01“…Medical workers can combine those relevant factors from the perspective of positive psychology, further explore the occurrence and development mechanism of PTG, and establish targeted interventions to promote PTG.…”
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47593
Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial
Published 2025-01-01“…However, research on the mechanism of action of OVs in humans and clinically relevant biomarkers is still sparse. …”
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47594
Respectful maternity care and associated factors among mothers who gave birth at public health institutions in Debre Tabor town, Northwest Ethiopia: a mixed-methods study
Published 2025-01-01“…Therefore, health institutions and other stakeholders should support and strengthen monitoring and evaluation mechanisms for maternal and neonatal healthcare providers and enhance education and constant support for women during their pregnancy and childbirth. …”
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47595
The genetic duet of concurrent RASAL1 and PTEN alterations promotes cancer aggressiveness by cooperatively activating the PI3K–AKT pathway
Published 2025-01-01“…This represents a robust genetic mechanism to promote human cancer.…”
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47596
Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy
Published 2023-01-01“…To explore the molecular mechanisms of the difference in therapeutic efficacy between PMME and NEMM, we performed genomic analysis, bulk RNA sequencing, and multiplex immunohistochemistry staining.Results We found that PMME (n=28) responded better to anti-PD-1 treatment than NEMM (n=64), with a significantly higher objective response rate (33.3% (95% CI 14.3% to 52.3%) vs 6.6% (95% CI 0.2% to 12.9%)) and disease control rate (74.1% (95% CI 56.4% to 91.7%) vs 37.7% (95% CI 25.2% to 50.2%)). …”
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47597
Exploring the role of inflammatory biomarkers in trigeminal neuralgia
Published 2025-02-01“…These findings provide novel insights into TN's inflammatory mechanisms, suggesting new avenues for targeted interventions.…”
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47598
Neurodevelopmental Disorders and Connective Tissue-Related Symptoms: An Exploratory Case-Control Study in Children
Published 2024-12-01“…These insights underscore the need for interdisciplinary research to explore the mechanisms linking neurodevelopmental and connective tissue disorders, aiming to improve diagnosis and management strategies.…”
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47599
Lycium barbarum polysaccharide inhibits retinal neovascularization and inflammation in vitro and in vivo
Published 2025-02-01“…AIM: To explore the effect and mechanism of Lycium barbarum polysaccharide (LBP) inhibiting retinal neovascularization. …”
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47600
Integrating Two-Tier Optimization Algorithm With Convolutional Bi-LSTM Model for Robust Anomaly Detection in Autonomous Vehicles
Published 2025-01-01“…Besides, the IWOAFS-XAIAD technique employs an improved whale optimization algorithm (IWOA)-based feature subset selection to pick an optimum set of features. An attention mechanism with the CNN-BiLSTM (CNN-BiLSTM-A) model is employed for anomaly detection and classification. …”
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