Altered immune surveillance of B and T cells in patients with persistent residual lung abnormalities 12 months after severe COVID-19 by Julio Flores-Gonzalez, Ivette Buendia-Roldan, Fernanda Téllez-Quijada, Carlos Peña-Bates, Lucero A. Ramón-Luing, Armando Castorena-Maldonado, Ramcés Falfán-Valencia, Gloria Pérez-Rubio, Moisés Selman, Leslie Chavez-Galan, Leslie Chávez-Galán

“…These immune imbalances may contribute to ongoing lung dysfunction and warrant further investigation as a potential mechanism in residual lung abnormalities. Larger studies are necessary to confirm these findings.…”
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A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer by Chenxi Lv, Tianwei Chen, Jiangtao Li, Yuqiang Shan, Hong Zhou

“…This finding provided valuable insights into the molecular mechanisms of tumor immunity in GC, offering potential avenues for targeted therapeutic interventions.…”
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Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae by Wei Yu, Peiyao Jia, Xiaobing Chu, Shengjie Li, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Yingchun Xu, Qiwen Yang

“…The ramR‐ramA regulatory system critically influences drug resistance by regulating the AcrAB‐TolC efflux pump, which also plays a crucial role in the pathogenicity of K. pneumoniae. However, the mechanism of the ramR‐ramA system on bacteria‐host interaction remains unclear. …”
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Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment by Meng Gao, Yu Wang, Liman Wei, Siyuan Li, Qiuyue Zhang, Zhongkang Yang, Mohan Bai, Yiming Yao, Lei Wang, Hongwen Sun

“…Therefore, given the continuous input and considerable persistence of NOPEs in offshore sediment, their toxic effects and mechanisms warrant thorough investigation. This study provides the first evidence for the occurrence, temporal trends, and potential risks of NOPEs in marine sediment environment.…”
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Recombinant α-Klotho Protein Alleviated Acute Cardiorenal Injury in a Mouse Model of Lipopolysaccharide-Induced Septic Cardiorenal Syndrome Type 5 by Xi Liu, Yangyang Niu, Xiaoqin Zhang, Yingying Zhang, Ying Yu, Jieli Huang, Jiangtao Li, Chen Yu

“…This study aimed to investigate the effects and mechanisms of α-klotho in septic cardiorenal injury. …”
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Phage-mediated virulence loss and antimicrobial susceptibility in carbapenem-resistant Klebsiella pneumoniae by Yanshuang Yu, Mengzhu Wang, Liuying Ju, Minchun Li, Mengshi Zhao, Hui Deng, Christopher Rensing, Qiu E. Yang, Shungui Zhou

“…These parallel evolutionary trajectories suggest a common genetic mechanism driving adaptation, ultimately favoring the efficacy of phage therapy. …”
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Do coping strategies mediate the effects of childhood adversities and traumata on clinical high-risk of psychosis, depression, and social phobia? A cross-sectional study on patient... by Zhixiong Chang, Naweed Osman, Carolin Martha Doll, Theresa Katharina Lichtenstein, Marlene Rosen, Eva Meisenzahl, Hanna Kadel, Joseph Kambeitz, Kai Vogeley, Frauke Schultze-Lutter

“…Conclusions Our findings underscore the complex interplay of the CAT domains and their relevant mediators with mental health outcomes that likely reflect underlying sex-specific psychological, social, cultural and neurobiological mechanisms. Supporting a broader view on CAT than the traditional focus on sexual abuse, results indicate an important role of emotional abuse that, descriptively, is most strongly mediated by maladaptive coping strategies on mental health outcomes. …”
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A generative whole-brain segmentation model for positron emission tomography images by Wenbo Li, Zhenxing Huang, Hongyan Tang, Yaping Wu, Yunlong Gao, Jing Qin, Jianmin Yuan, Yang Yang, Yan Zhang, Na Zhang, Hairong Zheng, Dong Liang, Meiyun Wang, Zhanli Hu

“…Moreover, a custom cross-attention module based on a cross-attention mechanism was constructed to effectively fuse the functional information and structural information. …”
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Small- to Large-Scale Electron Beam Powder Bed Fusion of Functionally Graded Steels by Carlos Botero, William Sjöström, Emilio Jimenez-Pique, Andrey Koptyug, Lars-Erik Rännar

“…The results obtained demonstrate the great potential to gradually tailor the composition, microstructure, mechanical properties, and wear resistance by combining different powders, and they suggest that any PBF-EB system can be repurposed to build gradient materials without hardware modification. …”
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Antibiotics Resistance in Escherichia coli Isolated from Livestock in the Emirate of Abu Dhabi, UAE, 2014–2019 by Ghada Elderdiri Abdelwahab, Hassan Zackaria Ali Ishag, Zulaikha Mohamed Al Hammadi, Saeed Mohamed S Al Yammahi, Mohd Faoruk Bin Mohd Yusof, Muna Sayed Y. Al Yassi, Shaikha Saeed A. Al neyadi, Asma Mohammed A. Al Mansoori, Fawzia Hassan A. Al Hamadi, Ibtesam Abdullah S. Al Hamadi, Mohamed Ali Abdalla Al Hosani, Salama Suhail Mohammed Al Muhairi

“…Bacterial culture and disk diffusion methods were used for bacterial isolation and phenotypic resistance analysis. Resistance mechanism was studied by PCR targeting the most commonly resistance genes: ampicillin (blaSHV, blaCMY, and blaTEM-1B), tetracyclines (tetA and tetB), co-trimoxazole [sulfamethoxazole (sul1, sul2, and sul3) + trimethoprim (dfrA1 and dfrA17)], aminoglycosides [aph(3'')-Ia, aph(6)-Id, and aac(3)-IV], and fluoroquinolones (qnrA and aac(6’)-Ib-cr). …”
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The effects of wind farm wakes on freezing sea spray in the mid-Atlantic offshore wind energy areas by D. Rosencrans, D. Rosencrans, J. K. Lundquist, J. K. Lundquist, J. K. Lundquist, M. Optis, M. Optis, N. Bodini

“…Ice accretion induces load and fatigue on mechanical parts, which reduces blade performance and power production. …”
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Goose astrovirus induces apoptosis and endoplasmic reticulum stress in gosling hepatocytes by Zhihua Lu, Haiqin Li, Xiaona Gao, Duanfeng Fu, Haoyu Huang, Cheng Huang, Meiqin Wu, Xiaoquan Guo

“…This study examined the roles and possible mechanisms of ERS and apoptosis in GoAstV-induced liver injury in goslings. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Future research should prioritize investigating the underlying pathological mechanisms and developing targeted preventive and management strategies. …”
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Effects of ursolic acid on growth performance, serum biochemistry, antioxidant capacity, and intestinal health of broilers by X.W. Zhang, X. Li, Y. Yin, M. Wang, Y.F. Wang, J.Y. Chen, Y.R. Zhao

“…However, the specific mechanism is still unclear. Therefore, the purpose of this study was to further explore whether UA promotes the growth of broilers by affecting the intestinal environment of broilers. …”
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“Knowledge was clearly associated with education.” epistemic positioning in the context of informed choice: a scoping review and secondary qualitative analysis by Niamh Ireland-Blake, Fiona Cram, Kevin Dew, Sondra Bacharach, Jeanne Snelling, Peter Stone, Christina Buchanan, Sara Filoche

“…Abstract Background Being able to measure informed choice represents a mechanism for service evaluation to monitor whether informed choice is achieved in practice. …”
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From Peril to Protection: an evaluation of regulations impacting eScooter injuries by Leslie M Kobayashi, Todd W Costantini, Jay J Doucet, Jarrett E Santorelli, Laura N Haines, Kendra M Black

“…This demonstrates the importance of advocacy efforts in response to changes in injury patterns and mechanisms of injury. We believe that our work can serve as a model for other urban centers seeking to reduce eScooter-related injuries and implement effective safety measures.Level of evidence IV, prognostic/epidemiologic.…”
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Identification of Differentially Expressed Genes in Metastatic and Non-Metastatic Nasopharyngeal Carcinoma Cells by Suppression Subtractive Hybridization by Xu-Yu Yang, Cai-Ping Ren, Lei Wang, Hui Li, Chun-Jie Jiang, Hong-Bo Zhang, Ming Zhao, Kai-Tai Yao

“…Local recurrences and metastasis occur frequently in patients with NPC and are a leading cause of death, despite improvements on treatment modalities. The molecular mechanism underlying the metastasis of nasopharyngeal carcinoma remains poorly understood, however, and requires additional elucidation. …”
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Enriched rehabilitation on brain functional connectivity in patients with post-stroke cognitive impairment by Yaping Huai, Weiwei Yang, Yichen Lv, Kui Wang, Hongyu Zhou, Yiqing Lu, Xiaoyun Zhang, Yaze Wang, Jibing Wang, Xin Wang

“…ObjectiveThis study aims to observe the effect of enrichment rehabilitation (ER) on cognitive function in post-stroke patients and to clarify its underlying mechanism.MethodsForty patients with post-stroke cognitive impairment (PSCI) meeting the inclusion criteria were randomly assigned to two groups: conventional medical rehabilitation (CM group) and ER intervention (ER group). …”
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Association among high blood pressure health literacy, social support and health-related quality of life among a community population with hypertension: a community-based cross-sec... by Ting Chen, Wei Gan, Li Song, Yujie Wang, Huan Qi, Qinghua Zhang, Jinyu Yin

“…However, the potential mechanism of HBP-HL, SS and HRQoL remains unclear. …”
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Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets by Huahua Li, Lingling Zou, Zhaowei Long, Junkun Zhan, Junkun Zhan

“…Immune cells, including T cells and monocytes, play a pivotal role in driving systemic inflammation in T2DM; however, the underlying single-cell mechanisms remain inadequately defined.MethodsSingle-cell RNA sequencing of peripheral blood mononuclear cells (PBMCs) from 37 patients with T2DM and 11 healthy controls (HC) was conducted. …”
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