Project ChemicalBlooms: Collaborating with citizen scientists to survey the chemical diversity and phylogenetic distribution of plant epicuticular wax blooms by Le Thanh Dien Nguyen, Nicole Groth, Kylie Mondloch, Edgar B. Cahoon, Keith Jones, Lucas Busta

“…Thus, our data suggest that a lineage‐specific mechanism other than biosynthesis exists that enables select species to generate triterpenoid‐rich surface wax crystals. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

“…In this study, we explored the roles of S100A8/A9 in modulating neuroinflammation and influencing TBI outcomes, delving into the underlying mechanisms. S100A8/A9-enriched neutrophils were present in the injured brain tissue of TBI patients, and elevated plasma levels of S100A8/A9 were correlated with poorer neurological function. …”
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Enhancing work environments and reducing turnover intention: a multicenter longitudinal cohort study on differentiated nursing practices in Dutch hospitals by Julia van Kraaij, Neeltje de Vries, Hanna Wessel, Hester Vermeulen, Catharina van Oostveen, RN2Blend Consortium

“…Future research should include longer term studies to fully understand the complex relationship and accompanying mechanisms between differentiated nursing practices, the nursing work environment, and turnover intention. …”
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Physical and emotional abuse with internet addiction and anxiety as a mediator and physical activity as a moderator by Jinyin Peng, Yang Liu, Xubo Wang, Zhenxiu Yi, Lei Xu, Fulan Zhang

“…Anxiety may be the internal mechanism of physical-emotional abuse affecting university students’ Internet addiction, and physical activity plays a moderator role in the relationship between physical-emotional abuse and university students’ Internet addiction. …”
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Investigating the Relationships between Internet Addiction and Suicidal Ideation in Adolescent Girls by Zeynab Akbari, Fatemeh Serjouie, Jafar Sarani Yaztappeh, Mohammad Hossein Turkzadeh, Faeze Ziaei, Ali Bagheri, Maryam Sate Zohd, Amir Sam Kianimoghadam

“…Using these findings, we can elucidate the mechanism of how IA affects individual SI, providing critical information for the development and implementation of targeted strategies and interventions to reduce SI among Iranian adolescent girls. …”
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The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells by Chien-Ting Lin, Shang-Ju Wu, Cheng Hao Liao, Reyhung Roc Weng, Chun-Ming Lin

“…To stimulate both innate and adaptive mechanisms, we created a bifunctional eCD16A/anti-CD3-BFP adapter protein for combined use with clinically approved monoclonal IgG1 antibodies. …”
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Comparative study of phenotypic and genotypic expression of virulence factors in colonizing and pathogenic carbapenem resistant Acinetobacter baumannii (CRAB) by Swati Sharma, Kamal Singh, Ashish Chaurasiya, Tuhina Banerjee, Royana Singh, Ghanshyam Yadav, Ashok Kumar

“…Biofilm formation, porins, micronutrient capturing mechanism and quorum sensing, provide protection against desiccation, host-pathogen killing and enhance its persistence. …”
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Granulocyte-Macrophage Colony-Stimulating Factor-Activated Neutrophils Express B7-H4 That Correlates with Gastric Cancer Progression and Poor Patient Survival by Zhi-guo Shan, Zong-bao Yan, Liu-sheng Peng, Ping Cheng, Yong-sheng Teng, Fang-yuan Mao, Kun Fan, Yuan Zhuang, Yong-liang Zhao

“…Our results illuminate a novel regulating mechanism of B7-H4 expression on tumor-activated neutrophils in GC, suggesting that functional inhibition of these novel GM-CSF-B7-H4 pathways may be a suitable therapeutic strategy to treat the immune tolerance feature of GC.…”
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Observed upper-ocean structure and seasonal production in the southern Kerguelen Plateau region, 1994-2021 by Man Liang, Annie Foppert, Annie Foppert, Karen J. Westwood, Karen J. Westwood, Sophie Bestley, Sophie Bestley

“…Observed relationships between upper water column characteristics and biological processes are discussed in terms of likely nutrient supply mechanisms and seasonal patterns of utilization.…”
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Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways by Nami Lee, Yu Jung Heo, Sung-E Choi, Ja Young Jeon, Seung Jin Han, Dae Jung Kim, Yup Kang, Kwan Woo Lee, Hae Jin Kim

“…NF-κB, MAPK, and JAK2/STAT signalling pathways were examined via Western blotting to elucidate the molecular mechanisms of anti-inflammation. Results. LPS-stimulated CD80+ M1 macrophages were suppressed by coincubation with empagliflozin, gemigliptin, and empagliflozin plus gemigliptin, respectively. …”
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Protective Effects of Two Safflower Derived Compounds, Kaempferol and Hydroxysafflor Yellow A, on Hyperglycaemic Stress-Induced Podocyte Apoptosis via Modulating of Macrophage M1/M... by Yuanping Li, Dan Zheng, Dayue Shen, Xilan Zhang, Xiaoyun Zhao, Hui Liao

“…The primary initiating mechanism in diabetes nephropathy (DN) is hyperglycemia-induced inflammation in which macrophage and podocyte play important roles. …”
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Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression by Tingting Xu, Jianmin Huang, Jiajing Lin, Yuanyuan Liu, Yi Wang, Wenkang Shen, Jianjie He, Shuyun Chen, Xi Zhu, Yuqin Que, Mengting Hu, Yu Chen, Liming Cheng, Honghao He, Xin Liu, Si Liu

“…Understanding these changes could improve our knowledge of molecular mechanisms, aiding in diagnostic improvements and therapeutic development.…”
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Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study by Xiujuan Dong, Cuicui Nie, Yanli Yin, Haixia Xu, Yanxia Zhang, Lihua Han, Congcong Xu

“…Background This study aimed to investigate the role of B7H4 and Fas in pre-eclampsia (PE) occurrence and development and reveal its potential mechanisms.Methods Thirty healthy individuals and 60 patients with PE were enrolled in the study. …”
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Resveratrol amplifies the anti-tumor effect of α-PD-1 by altering the intestinal microbiome and PGD2 content by Baohua Luo, Qingling An, Jingyu Lei, Dengxu Tan, Xiaoqiu Liu, Hui Li, Yong Zhao, Jing Qin, Caiqin Zhang, Yongbin Zhang, Changhong Shi

“…In addition, I6S sequencing was performed on mouse fecal samples, and metabolomic analyses were performed on plasma samples to understand the characteristics of the intestinal microbiome and metabolites to explore the potential mechanism of anti-tumor immunity mediated by combined immunotherapy. …”
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Combined Transplantation of Adipose Tissue-Derived Stem Cells and Endothelial Progenitor Cells Improve Diabetic Erectile Dysfunction in a Rat Model by Qiyun Yang, Wanmei Chen, Chi Zhang, Yun Xie, Yong Gao, Cuncan Deng, Xiangzhou Sun, Guihua Liu, Chunhua Deng

“…Combined transplantation of ADSCs and EPCs has a synergic effect in repairing the endothelial function of DED rats, and the underlying mechanism might be the paracrine of VEGF and SDF-1 by ADSCs, which improves the recruitment and proliferation of EPCs in the cavernosum.…”
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Shaking Table Test for Evaluating the Seismic Performance of Steel Frame Retrofitted by Buckling-Restrained Braces by Tingting Wang, Jianhua Shao, Chao Zhao, Wenjin Liu, Zhanguang Wang

“…The failure modes, dynamic characteristics, acceleration response, interstory drift ratio, strain, shear force, and other mechanical properties of those two comparative structures subjected to different levels of seismic waves are mainly evaluated by the experiment. …”
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Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis by Nahid Rezazadeh, Effat Alizadeh, Somaieh Soltani, Soodabeh Davaran, Neda Esfandiari

“…The swelling ratio and mechanical strength of the scaffolds were evaluated experimentally. …”
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Effects of Nitrogen Fertilization on Soil CH₄, CO₂, and N₂O Emissions and Their Global Warming Potential in Agricultural Peatlands by Yao Shi, Xiaowei Wei, Lianxi Sheng, Xuechen Yang

“…Here, we elucidate the characterization of CH₄, CO₂ and N₂O emissions from the soil surface and different depths of the soil profile during the growing season of agricultural peatlands for over 50 years and the mechanisms of their resulting global warming potential (GWP) impact through field monitoring and molecular techniques. …”
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Fortifying plant fortresses: siderophores in defense against Cercospora leaf spot disease in Vigna radiata L. by Anushree Kamath, Abhishek Sharma, Arpit Shukla, Arpit Shukla, Arpit Shukla, Paritosh Parmar, Dhara Patel

“…Siderophores, specialized iron-chelating molecules produced by Bacillus amyloliquefaciens D5, were investigated for their role in enhancing plant defense mechanisms against Cercospora canescens in mung bean (Vigna radiata L.). …”
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Effects of Quetiapine on Novelty‐Related Object Recognition Memory and Hippocampal BDNF Level in Sleep‐Deprived Rats by Öznur Özge Özcan, Burcu Çevreli, Emel Serdaroğlu Kaşıkçı, Mesut Karahan, Muhsin Konuk

“…ABSTRACT Background The underlying mechanism of quetiapine (QET) in treating cognitive impairment in sleep deprivation is unclear. …”
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