Genome-wide identification and characterization of WRKYs family involved in responses to Cylindrocarpon destructans in Panax notoginseng by Manqiao Li, Xiaoli Che, Qiwen Liang, Kuixiu Li, Guisheng Xiang, Xuyan Liu, Yan Zhao, Fugang Wei, Shengchao Yang, Guanze Liu

“…These findings provide a foundation for future exploration of the mechanism underlying P. notoginseng resistance to root rot disease.…”
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Association between Chinese visceral adiposity index and lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH): a national cohort study by Kunhui Chang, Bo Li, Gang Wang, Hao Zhou, Yonghao Chen, Hongbing Gu

“…Further prospective studies are needed to confirm these findings and elucidate the underlying mechanisms.…”
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Moscatilin inhibits vascular calcification by activating IL13RA2-dependent inhibition of STAT3 and attenuating the WNT3/β-catenin signalling pathway by Tingting Zhang, Mengmeng Zhu, Jialing Ma, Zhenghong Liu, Zhidan Zhang, Meijie Chen, Yaping Zhao, Huaxin Li, Shengnan Wang, Xiaoning Wei, Wenwen Zhang, Xiaoxiao Yang, Peter J. Little, Danielle Kamato, Hao Hu, Yajun Duan, Baotong Zhang, Jianbo Xiao, Suowen Xu, Yuanli Chen

“…Objectives: This study was designed to test the therapeutic effects and mechanism of Moscatilin (also known as dendrophenol) from Dendrobium huoshanense (an eminent traditional Chinese medicine) in suppressing vascular calcification in vitro, ex vivo and in vivo. …”
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Evaluation of Four Multiple Imputation Methods for Handling Missing Binary Outcome Data in the Presence of an Interaction between a Dummy and a Continuous Variable by Sara Javadi, Abbas Bahrampour, Mohammad Mehdi Saber, Behshid Garrusi, Mohammad Reza Baneshi

“…We first selected secondary data and devised an experimental design that consisted of 40 scenarios (2 × 5 × 4), which differed by the rate of simulated missing data (10%, 20%, 30%, 40%, and 50%), the missing mechanism (MAR and MCAR), and imputation method (MICE-Interaction, MICE-CART, MICE-RF, and MICE-Stratified). …”
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YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway by Tai Tian, Shiming He, Han Hao, Bao Guan, Yanqing Gong, Jian Fan, Zhenpeng Zhu, Wenzhi Gao, Yucai Wu, Ninghan Feng, Aixiang Wang, Yuexian Guo, Xuesong Li

“…Abstract Objective This study aims to investigate the molecular mechanisms by which YWHAG (Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma) promotes metastasis in bladder cancer. …”
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Digital modeling of soil-borne fusarium’s nutritional: Investigating microbiological and microecological dynamics in Moroccan agroecosystems by El Hilali Alaoui Youssef, Bouda Said, Chabaa Samira, Elouali Alami Mohammed, Khoudi Zakaria, Essarioui Adil

“…This study aimed to elucidate the biological mechanisms associated with Bayoud decline in suppressive soils. …”
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Transformer-Based Person Detection in Paired RGB-T Aerial Images With VTSaR Dataset by Xiangqing Zhang, Yan Feng, Nan Wang, Guohua Lu, Shaohui Mei

“…VTSaRNet integrates the instance segmentation for copy–paste mechanism (ISCP) using a Union Transformer Network that functions in both Visible (V) and Thermal (T) bimodalities. …”
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Investigating the relationship between prenatal androgen exposure and sleep quality: a comprehensive study using anthropometric measurements, questionnaires, actigraphy, and polyso... by Adrian Bartoszek, Magdalena Sawic, Karol Pierzchała, Aleksandra Kudrycka, Piotr Białasiewicz, Wojciech Kuczyński

“…These findings underscore the potential long-term impacts of PAE on sleep health and emphasize the need for further research into gender-specific sleep regulation mechanisms.…”
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WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway by Dongmei Cheng, Yang Bao, Xue Wang, Haidong Xiang, Tianyuan Guo, Yong Du, Zhiyong Zhang, Han Guo

“…Abstract Background Dental pulp stem cells (DPSCs) possess capability of multidirectional differentiation, and their cementogenic differentiation potential enables them to participate in cementum repair and regeneration. The molecular mechanisms underlying cementogenic differentiation of DPSCs remain unclear. …”
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Macro-environment oscillation notably up risk of water quality degradation: A case study in Shanxi Reservoir, China by Wangwei Cai, Jihong Xia, Zewen Liu, Jiayi Zu, Shuyi Ji, Yue Wang, Qihua Wang

“…It can be influenced by the macro-processes of meteorology, hydrology, and pollution. However, the mechanism of macro-environment affect water quality risk still is unclear. …”
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Study of photosynthetic pigments in the hyperhaline Kuyalnik Estuary and its inflows (Ukraine, north-western Black sea region) by G. M. Shykhaleyeva, G. M. Kiryushkina, Yu. Yu. Yurchenko

“…It has been revealed that in the periods of low water content in KE and high salinization of its waters production activity is insignificant, but it does not stop. Adaptive mechanisms of algal communities in relation to extreme conditions of KE (salinization, decreasing of water level and increase of water temperature, decreasing of freshwater inflow) are expressed in an increase in the share of auxiliary pigments (chlorophylls "b" and "c"). …”
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Heterologous Expression of a Potential ‘<i>Paulownia fortunei</i>’ MYB Factor Gene, <i>PfMYB90</i>, Improves Salt and Cold Tolerance in <i>Arabidopsis</i> by Hongling Wang, Shizheng Shi, Guijie Luo, Ruifang Huang, Dezong Sui, Yunpeng Gao, Lei Wang

“…In this study, we performed bioinformatics analysis of the stress-related gene PfMYB90, a potential transcription factor, and investigated its mechanism of action under salt and cold stresses. <i>PfMYB90</i> was strongly expressed in the fully unfolded leaf and root of plants in both stress treatments. …”
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Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway by Minxia Zuo, Cheng Meng, Qian Song, Zhongai Gao, Xiao Cui, Jingyu Wang, Yongmei Li, Xiaochen Li, Chunyan Shan, Juhong Yang, Baocheng Chang

“…Here, we explored whether an excessive ketone body level causes kidney injury and the potential underlying mechanism. Methods. Fifty-six type 2 diabetes without ketosis (NDK group), 81 type 2 diabetes with ketosis (DK group), and 38 healthy controls (NC group) were enrolled. …”
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Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…Abstract Background To investigate the functional characteristics of heterozygous variants in the SALL1 gene in two children with Townes-Brocks syndrome (TBS), as well as the underlying mechanisms leading to chronic kidney disease. Methods We retrospectively analyzed the clinical manifestations, laboratory findings, and genetic backgrounds of two TBS patients admitted to our hospital presenting with chronic kidney disease stage 2 and focal segmental glomerulosclerosis (FSGS). …”
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Atmospheric Wet Deposition of PCDD/Fs in the Ambient Air by Xueying Tian, Kangping Cui, Hwey-Lin Sheu, Yen-Kung Hsieh, Fanxuan Yu

“…Abstract Wet deposition is an important mechanism for removing air pollutants from the atmosphere. …”
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Novel combination strategy of high intensity focused ultrasound (HIFU) and checkpoint blockade boosted by bioinspired and oxygen-supplied nanoprobe for multimodal imaging-guided ca... by Ying Zhou, Chen Cheng, Qi Wang, Min Zheng, Pan Li, Yang Zhou, Yuting Cao, Li Wan, Xun Guo, Xiaohong Lin, Rui Tang, Hongye He, Nianhong Wu, Qiaoqi Chen, Yaqin Hu, Xialin Xiong, Faqi Li

“…Flow cytometry and immunofluorescence were used to clarify the potential mechanism of HIFU+M@P-SOP and their role in anti-programmed death ligand-1 (PD-L1) therapy.Results Guided by photoacoustic/MR/ultrasound (US) multimodal imaging, M@P-SOP was abundantly enriched in tumor, which greatly enhanced HIFU’s killing of tumor tissue in situ, induced stronger tumor immunogenic cell death, stimulated dendritic cell maturation and activated CD8+ T cells. …”
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Improvement of engineering properties and environmental impact of fired clay bricks utilizing industry sludge waste by Amir Detho, Aeslina Abdul Kadir, Ahmad Shayuti, Bin Abdul Rahim, Nejib Ghazouani, Abdelkader Mabrouk, Ahmed Babeker Elhag, Hesham Hussein Rassem

“…Incorporating up to 30% of body mill sludge (BS) and polishing sludge (PS) into the brick mix significantly enhances physical and mechanical properties, resulting in reduced shrinkage, increased porosity, and improved compressive strength, reaching up to 25 N/mm². …”
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Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells by Yujing Tao, Yujing Tao, Qun Niu, Qun Niu, Yuanqian Yao, Yuanqian Yao, Kaixin Wang, Kaixin Wang, Haijian Dong, Haijian Dong, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Hui Li

“…In this study, we explored the effects and potential mechanisms of Qizhu-Ruogan-Granules (QZRG), a formulation from the Affiliated Hospital of the Chengdu University of TCM, on carbon tetrachloride (CCl4)-induced liver fibrosis in mice.MethodsA total of 40 male C57BL/6J mice were randomly divided into five groups (n = 8 per group), with liver fibrosis induced by injecting 10% CCl4 for 15 weeks. …”
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Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury by Fang Chen, Yi Hu, Yuetao Xie, Zonghui Zhao, Lin Ma, Zhili Li, Wanlong Tan

“…This study was aimed at exploring the role of TGP in RI/RI and its underlying mechanism of action. Methods. Rat RI/RI models were constructed by surgical operation. …”
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Application of synthesized Fe3O4@Gelatin nanoparticles on interfacial properties and enhanced oil recovery by Hossein Ghalenavi, Abdolhossein Hemmati-Sarapardeh, Mahin Schaffie, Saeid Norouzi-Apourvari

“…They enhance oil recovery by improving EOR mechanisms including decreasing interfacial tension (IFT), wettability alteration to water-wet, and preventing asphaltene precipitation. …”
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