SS-YOLO: A Lightweight Deep Learning Model Focused on Side-Scan Sonar Target Detection by Na Yang, Guoyu Li, Shengli Wang, Zhengrong Wei, Hu Ren, Xiaobo Zhang, Yanliang Pei

“…Finally, we use an improved multi-head self-attention (MHSA) mechanism in the detection head, replacing the original complex convolution structure, to enhance the model’s ability to focus on important features with low computational load. …”
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Azithromycin Promotes the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells after Stimulation with TNF-α by Tingting Meng, Ying Zhou, Jingkun Li, Meilin Hu, Xiaomeng Li, Pingting Wang, Zhi Jia, Liyu Li, Dayong Liu

“…This study investigated the effects and underlying mechanisms of azithromycin (AZM) treatment on the osteogenic differentiation of human periodontal ligament stem cells (PDLSCs) after their stimulation with TNF-α in vitro. …”
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Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma by Lijuan Wang, Qian He, Weijun Qin, Xiyu Song, Yumeng Zhu, Wenwen Geng, Jianhua Jiao, Hongjiao Liu, Ruo Chen, Xiuxuan Sun, Jiejie Geng, Zhinan Chen

“…However, the spatial and functional heterogeneity of immunosuppressive cells and the mechanisms by which their interactions promote immunosuppression in the ccRCC have not been thoroughly investigated.Methods To further investigate the cellular and regional heterogeneity of ccRCC, we analyzed single-cell and spatial transcriptome RNA sequencing data from four patients, which were obtained from samples from multiple regions, including the tumor core, tumor-normal interface, and distal normal tissue. …”
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The genomes of Scedosporium between environmental challenges and opportunism by Francesco Venice, Federica Spina, Domenico Davolos, Stefano Ghignone, Giovanna Cristina Varese

“…Many efforts have been made to understand the mechanisms underlying pathogenicity in bacteria, and OMICs techniques are largely responsible for those advancements. …”
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Salutogenic Environmental Health Model—proposing an integrative and interdisciplinary lens on the genesis of health by Jule Anna Pleyer, Laura Dominique Pesliak, Annette Konstanze Fides Malsch, Annette Konstanze Fides Malsch, Timothy McCall, Timothy McCall

“…Within the salutogenic paradigm, health promotion is focused on understanding the mechanisms of health development. Models serve as indispensable tools. …”
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New insights in the low-temperature-dependent formation of amorphous titania-coated magnetic polydopamine nanocomposites for the adsorption of methylene blue by Jiangqun Zhang, Xingyu Long, Meng Hu, Wanli Wei, Jiangning Gong, Chun Yang, Pinhua Xia, Anping Wang

“…The studies on the formation mechanism of FPaT indicated that the reaction temperature was the most important parameter affecting crystal structure. …”
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Granger Test and ARDL Model for the Socio-Economic Challenges Investigation: Public Expenditure Components, Economic Growth, and Inflation by Fatma Zohra Hamadouche, Bekhta Hamadouche, Malak Mohammad Ghandour, Aicha Hamadouche, Brahim Boutrig

“…The error correction term (-0.75) highlights a strong adjustment mechanism, with deviations from long-term equilibrium corrected within approximately 16 months. …”
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Safety and efficacy of mesenchymal stromal cells mitochondria transplantation as a cell-free therapy for osteoarthritis by Ana Maria Vega-Letter, Cynthia García-Guerrero, Liliana Yantén-Fuentes, Carolina Pradenas, Yeimi Herrera-Luna, Eliana Lara-Barba, Felipe A. Bustamante-Barrientos, Masyelly Rojas, María Jesús Araya, Nicole Jeraldo, Constanza Aros, Francisca Troncoso, Daniela Poblete, Angela Court, Alexander Ortloff, Jose Barraza, Francesca Velarde, Carlos Farkas, Claudio Carril, Noymar Luque-Campos, Gonzalo Almarza, Maximiliano Barahona, Jose Matas, Lucas Cereceda, Rocío Lorca, Jorge Toledo, Karina Oyarce, Rolando Vernal, Andrés Caicedo, Andrea del Campo, Yessia Hidalgo, Roberto Elizondo-Vega, Farida Djouad, Maroun Khoury, Fernando E. Figueroa, Patricia Luz-Crawford

“…In recent years, it has been proposed that mesenchymal stromal cells (MSC) transfer their functional mitochondria to damaged cells in response to cellular stress, becoming one of the mechanisms underpinning their therapeutic effects. Therefore, we hypothesize that a novel cell-free treatment for OA could involve direct mitochondria transplantation, restoring both cellular and mitochondrial homeostasis. …”
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Spatiotemporal Variations of PM2.5 and O3 Relationship during 2014–2021 in Eastern China by Yasong Li, Tijian Wang, Qin’geng Wang, Yawei Qu, Hao Wu, Min Xie, Mengmeng Li, Shu Li, Bingliang Zhuang

“…Conducting a comprehensive spatiotemporal analysis of the relationship between them is crucial to gain insights into their interaction mechanisms and developing regulation measures. We quantified the spatiotemporal variations of them in the Yangtze River Delta (YRD) utilizing long-term integrated data during 2014–2021 and examined the evolution of their relationship at different time scales through statistical analysis. …”
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The effect of immunosuppression on outcomes in elderly patients with community-acquired pneumonia by Lixue Huang, Bingxuan Weng, Yuanqi Wang, Mengyuan Wang, Yin Mei, Wei Chen, Meng Ma, Jingnan Li, Jianzhen Weng, Yang Ju, Xuefeng Zhong, Xunliang Tong, Yanming Li

“…There were no differences between the two groups in vital signs, oxygenation, admission laboratory tests, need for mechanical ventilation and intensive care unit admission, except for a lower lymphocyte count in the ICH group (0.9*10^9/L, IQR 0.6–1.3*10^9/L [ICH group] vs. 1.2*10^9/L, IQR 0.8–1.7*10^9/L [non-ICH group]; p < 0.001). …”
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Examining the association between public health unit spending and adolescent substance use by Urvi Rai, Karen A. Patte, Brendan T. Smith, Ambikaipakan Senthilselvan, Elaine Hyshka, Scott T. Leatherdale, Roman Pabayo

“…The present study reports mixed results, warranting further prospective research to explore the directions and mechanisms of the associations found.…”
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Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats by Emmanuel Nnaemeka Uhuo, Simeon Ikechukwu Egba, Chiemeziem Adnma Obike, Paul Ndubuisi Anyiam, Prince Ogochukwu Alaebo, Pryanka Munachiso Okeke, Emmanuella Chinaza Obinali

“…TP-200 and TP-400 presented relatively normal prostatic histomorphology compared with TP. Conclusion: The mechanisms of BPH inhibition involve the regulation of sex hormone levels and the amelioration of conditions caused by oxidative damage. …”
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Protective role of ginsenoside Rg1 in the dynamic progression of liver injury to fibrosis: a preclinical meta-analysis by Lijuan Dan, Xiuyan Li, Shuanglan Chen, Xiaojie You, Dong Wang, Tianyuan Wang, Jia Li, Wenping Liu, Jie Mu, Quansheng Feng, Quansheng Feng

“…This study evaluated the efficacy and underlying mechanisms of ginsenoside Rg1 in animal models of liver injury and fibrosis, and providing a basis for future clinical investigation.MethodsA systematic review was conducted on preclinical studies published in PubMed, Web of Science, and Embase databases up to 1 August 2024, adhereing to rigorous quality standards. …”
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Effect of Electroacupuncture on Shoulder Subluxation in Poststroke Patients with Hemiplegic Shoulder Pain: A Sham-Controlled Study Using Multidimensional Musculoskeletal Ultrasound... by Minghong Sui, Naifu Jiang, Luhui Yan, Jiaqing Liu, Bin Luo, Chenxi Zhang, Tiebin Yan, Yun Xiang, Guanglin Li

“…Our findings further reveal the analgesic mechanism of EA on hemiplegic shoulder pain following stroke.…”
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Self-reported health, persistent symptoms, and daily activities 2 years after hospitalization for COVID-19 by Roda Alhasan, Lena Rafsten, Lena Rafsten, Alexandra C. Larsson, Alexandra C. Larsson, Katharina S. Sunnerhagen, Katharina S. Sunnerhagen, Katharina S. Sunnerhagen, Hanna C. Persson, Hanna C. Persson

“…Further research is important to unravel the mechanisms of long-term symptoms following COVID-19 and to develop effective therapeutic and rehabilitative interventions.…”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…The major compound of the studied extract, namely, p-hydroxybenzoic acid, was chosen for a molecular docking technique to discover the inhibition mechanism toward antioxidant proteins. In addition, a detailed molecular dynamics simulation was carried out to examine the thermodynamic stability of the produced intermolecular interactions. …”
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Assessing inflammatory protein factors in inflammatory bowel Disease using multivariable mendelian randomization by Qiang Su, Yun Lu, Song He, Jiang Liang, Song Huang, Yuanli He, Zhenxiang An

“…These findings provide novel insights into the biological mechanisms of IBD, and have implications for the screening, prevention, and treatment of IBD.…”
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The BASIDIN effector of the fungus Moniliophthora perniciosa promotes positive effects on the seed germination and seedlings development of Lactuca sativa by Keilane Silva Farias, Monaliza Macêdo Ferreira, Ivina Barbosa De Oliveira, Ronaldo José Durigan Dalio, Carlos Priminho Pirovani

“…Plant resistance inducers that activate plant defense mechanisms may be useful in reducing agrotoxic use. …”
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Insulin Resistance Markers to Detect Nonalcoholic Fatty Liver Disease in a Male Hispanic Population by Maritza Pérez-Mayorga, Jose P. Lopez-Lopez, Maria A. Chacon-Manosalva, Maria G Castillo, Johanna Otero, Daniel Martinez-Bello, Diego Gomez-Arbelaez, Daniel D. Cohen, Patricio Lopez-Jaramillo

“…Nonalcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver disease and is closely associated with cardiometabolic disorders, being insulin resistance (IR) the common pathogenic mechanism. The triglycerides/glucose (TyG) index and triglycerides/HDL-c (TG/HDL) ratio are markers correlated with IR. …”
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Effect of extracted phycocyanin by-products as a synbiotic supplement on the production performance and intestinal morphology of broilers by Kannikar Hamprakorn, Buaream Maneewan, Wantamas Jantasin, Mohd Nizam Lani, Tossapol Moonmanee, Julakorn Panatuk

“…Further research is recommended to explore the mechanisms underlying these effects and their implications for long-term poultry health and productivity.…”
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