To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway by Jia-Rong Gao, Xiu-Juan Qin, Zhao-Hui Fang, Li-Shan, Li-Ping Han, Hui-Jiang, Ming-Fei Guo, Nan-Nan Jiang

“…This study was to determine the influence of high glucose and related mechanism of vascular lesion of type 2 diabetes mellitus pathogenesis. …”
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Microplastic polymers in shellfish and fish in the coastal area by S. Basri K., A. Daud, A.B. Birawida, M. Maming, H.J. Mukono, D.S. Arsyad

“…Sample preparation, including enzymatic digestion and mechanical destruction, was performed to separate the organic tissues of fish and shellfish into small particles. …”
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The skin manifestations in end-stage renal disease patients in Jordan, single-center experience by Mohammad Hassan Al-thnaibat, Heba M. Urabi, Hadeel S. Alkofahi, Ola Mohannad Alshriedeh, Raneem Alshraideh, Hanan Esmadi, Ahmed Sheyyab, Bakri Roumi Jamal, Hanan Khaled Hasan

“…Moving forward, targeted research into the underlying mechanisms and innovative therapeutic approaches is essential to enhance both dermatological outcomes and overall patient well-being.…”
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Ac2-26 Alleviates Brain Injury after Cardiac Arrest and Cardiopulmonary Resuscitation in Rats via the eNOS Pathway by Jing Gong, Qi-Hang Tai, Guang-Xiao Xu, Xue-Ting Wang, Jing-Li Zhu, Xiao-Qing Zhao, Hai-Bin Sun, Dan Zhu, Wei Gao

“…This study is aimed at determining the mechanism by which Ac2-26 protects against inflammation during brain injury following CA and CPR. …”
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Mechanistic insights into “Three Methods and Three Acupoints” Tuina therapy for improving spinal microcirculation and motor function in sciatic nerve injury model rats by Hanyu Zhang, Yingqi Zhang, Hourong Wang, Jiayue Liu, Jiawei Sun, Jinping Chen, Zhifeng Liu, Tianyuan Yu, Jian Shu

“…Conclusion: TMTP Tuina therapy may restore motor function in rats, enhance ventral horn motor neuron morphology, and promote angiogenesis and vascular smooth muscle proliferation. The mechanism may involve the activation of the PI3K/Akt signaling pathway.…”
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Relevance of anxiety in clinical practice of Guillain-Barré syndrome: a cohort study by Raphaël Porcher, Djillali Annane, Andrea Polito, Tarek Sharshar, Takoua Merhbene, Morgane Blanc, Marion Antona, Marie-Christine Durand, Diane Friedman, David Orlikowski, Marie-Hélène Marcadet

“…Either language barrier or cognitive decline that precluded understanding was considered as exclusion criteria.Primary outcome Acute respiratory failure.Interventions At admission, anxiety and clinical factors (including known predictors of respiratory failure: delay between GBS onset and admission, inability to lift head, vital capacity (VC)) were assessed and related to subsequent need for mechanical ventilation (MV). Anxiety was assessed using a Visual Analogical Scale (VAS), the State Anxiety Inventory form Y1 (STAI-Y1) score and a novel-specific questionnaire, evaluating fears potentially triggered by GBS. …”
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Factors influencing participation in physical activity for persons living with dementia in rural and northern communities in Canada: a qualitative study by Chelsea Pelletier, Laura Elizabeth Middleton, Shannon Freeman, Kirsten Ward, Lauren Bechard, Kayla Regan, Salima Somani

“…Limited capacity in the health system to support physical activity due to a lack of referrals, poor communication mechanisms and limited resources for programming created challenges for physical activity participation. …”
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Zinc oxide seed priming enhances drought tolerance in wheat seedlings by improving antioxidant activity and osmoprotection by Rasha M. El-Shazoly, A. A. Othman, Muhammad Saqlain Zaheer, Ahmed F. Al-Hossainy, Dalia A. Abdel-Wahab

“…In conclusion, the application of ZnO NPs or bulk ZnO was found to create effective mechanical and physiological barriers, as confirmed by the analysis of antioxidant enzyme activities, nonenzymatic components, free radical scavenging, and osmoprotectant constituents.…”
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Sox9-Increased miR-322-5p Facilitates BMP2-Induced Chondrogenic Differentiation by Targeting Smad7 in Mesenchymal Stem Cells by Yongsheng Zeng, Chengcheng Du, Pengcheng Xiao, Yiting Lei, Piao Zhao, Zhenglin Zhu, Shengqiang Gao, Bowen Chen, Shengwen Cheng, Wei Huang, Chen Zhao

“…Therefore, the underlying mechanism is not clear. Currently, an increasing number of studies have shown that microRNAs play a pivotal role in chondrogenic and pathophysiological processes of cartilage. …”
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High Frequency of AIFM1 Variants and Phenotype Progression of Auditory Neuropathy in a Chinese Population by Hongyang Wang, Dan Bing, Jin Li, Linyi Xie, Fen Xiong, Lan Lan, Dayong Wang, Jing Guan, Qiuju Wang

“…To decipher the genotype-phenotype correlation of auditory neuropathy (AN) caused by AIFM1 variations, as well as the phenotype progression of these patients, exploring the potential molecular pathogenic mechanism of AN. A total of 36 families of individuals with AN (50 cases) with AIFM1 variations were recruited and identified by Sanger sequencing or next-generation sequencing; the participants included 30 patients from 16 reported families and 20 new cases. …”
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Simple hypertrophic tonsils have more active innate immune and inflammatory responses than hypertrophic tonsils with recurrent inflammation in children by Qun Huang, Hu Hua, Wei Li, Xi Chen, Lei Cheng

“…These differences, together with the patient’s clinical manifestations, suggest that tonsillar hypertrophy might be regulated by diverse immune and/or inflammatory mechanism through which novel therapeutic strategies might be created.…”
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The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…Conclusion: In conclusion, the current data highlight a potential benefit of JQ1 administration to counteract obesity, suggesting epigenetic modulation as a prospective target in the treatment of obesity and sarcopenic obesity, despite the underlying multiorgan molecular mechanism is still not completely elucidated.…”
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Technical progress of construction and safe operation of underground gas storage under complex geological conditions by Qiqi WANYAN, Yun WANG, Dongxu LI, Hongcheng XU, Chun LI, Kang LI, Jingcui LI, Lifeng LI

“…It is suggested to carry out special research to perfect the dynamic mechanism of fault sealing weakening of geological bodies. …”
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Experimental Study on the Characteristics of Adsorbed Gas and Gas Production in Shale Formations by Zhiming Hu, Xianggang Duan, Nan Shao, Yingying Xu, Jin Chang, Rui Shen, Xueke Chen

“…Adsorbed gas and free gas both exist in shale reservoirs simultaneously due to the unique nanoscale pore structure, resulting in the complex flow mechanism of gas in the reservoir during the development process. …”
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The impact of prolonged blockade of the releasing hormone on alterations in cardiac macrophage polarisation subsequent to quercetin administration in rats by T.A. Voroshylova, V.I. Shepitko, Ye.V. Stetsuk, N.V. Boruta, O.V. Vilkhova, M.V. Rud, G.S. Puzyryov, O.V. Sych, А.A. Miahkokhlib

“…The extracellular matrix provides structural support and mechanical signals for resident cells, and stores biologically active signaling molecules. …”
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Investigating the correlation of hip circumference to cardiovascular disease and type‐2 diabetes using Mendelian randomization by Hongtao Liu, Zhaoyu Li, Su Yan, Shaopeng Ming

“…Further research is needed to validate these findings and explore underlying mechanisms.…”
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Herbal HuoXueTongFu Formula with anti-inflammatory and fibrinolytic activity regulation for the prevention of postoperative peritoneal adhesions by Lili Yang, Lili Yang, Yali Wang, Yali Wang, Zhengjun Li, Zhengjun Li, Wen Li, Yanqi Chen, Ziyang Kong, Huixiang Zhang, Jiafei Wu, Mingqi Shang, Ming Li, Yaoyao Bian, Yaoyao Bian, Yaoyao Bian, Li Zeng, Li Zeng

“…However, the specific mechanism of HXTF on PPA formation within the time-to-treatment window has not been fully elucidated. …”
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Nitrogen and water additions with or without mowing altered soil microbial community characteristics in a semi-arid steppe by Hao Liu, Feirong Ren, Shiqiang Wan, Shijie Han, Junqiang Zheng

“…Bacterial, fungal, and protist communities varied in their assembly mechanisms, and their assembly processes differed in response to the three global change factors. …”
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Potential Biomarkers for Predicting the Risk of Developing Into Long COVID After COVID‐19 Infection by Zhiyong Hou, Yu Ming, Jun Liu, Zhong Wang

“…Conclusions In summary, we identified a subgroup of potential biomarkers for predicting the risk of the progression into long COVID after COVID‐19 infection, which could be partly elucidation of the associated molecular mechanisms for long COVID.…”
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MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells by Hou Lingli, Liu Qi, Zhao Ying, Yang Hongwei, Meng Qingying, Yu Fei

“…However, its role and molecular mechanisms in breast carcinoma are not fully explored. …”
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