Development of a pandemic-related core set of quality indicators for quality and patient safety in University Hospitals in Germany by Janis Evers, Natalie Altschuck, Claudia Mehl, Lilly Rüthrich, Lorenz Harst, Felix Walther, Oliver Steidle, Arnt Suckow, Ruth Hecker, Jochen Schmitt, Max Geraedts

“…Therefore, the aim of this work was to develop a set of indicators suited to detect undesirable developments concerning the provision of inpatient healthcare. Material & methods The study employed a literature review, online surveys, expert interviews, and a multistep evaluation process to develop a core set of quality indicators (QIs) suitable for assessing the resilience of university hospitals during pandemics. …”
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Evaluating a targeted selective speech, language, and communication intervention at scale – Protocol for the Happy Talk cluster randomised controlled trial. [version 3; peer review... by Pauline Frizelle, Darren Dahly, Aoife O'Shea, Aileen Murphy, Cristina McKean

“…More details on the composition, roles and responsibilities of each committee can be found in the supplemental material.…”
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Advancing arabic dialect detection with hybrid stacked transformer models by Hager Saleh, Hager Saleh, Hager Saleh, Abdulaziz AlMohimeed, Rasha Hassan, Mandour M. Ibrahim, Saeed Hamood Alsamhi, Moatamad Refaat Hassan, Sherif Mostafa

“…The rapid expansion of dialectally unique Arabic material on social media and the internet highlights how important it is to categorize dialects accurately to maximize a variety of Natural Language Processing (NLP) applications. …”
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Analysis of the sensitization activity of Moringa oleifera leaves protein by Juan Lu, Juan Lu, Xiaoxue Liu, Xiaoxue Liu, Wenjie Li, Wenjie Li, Chuyu Xi, Chuyu Xi, Dan Feng, Dan Feng, Shuang Song, Shuang Song

“…The optimal combination of extraction process was: extraction time of 6 h, material-liquid ratio of 1:8, and ammonium sulfate saturation of 60%. …”
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Treatment of neovascular age-related macular degeneration: one year real-life results with intravitreal Brolucizumab by Settimio Rossi, Carlo Gesualdo, Ernesto Marano, Raffaele Perrotta, Maria Consiglia Trotta, Antonio Del Giudice, Francesca Simonelli

“…Finally, the presence of subretinal hyperreflective material correlates with lower visual recovery.DiscussionOur findings highlight the efficacy of Brolucizumab in managing wet-AMD and suggest its role for long-term efficacy in stabilizing retinal exudation and fluid accumulation, resulting in improved visual prognosis.…”
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‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: e... by Joseph Rujumba, Carmen Roebersen, Susan Namara, Richard Ochen, Sharon Eva Ahumuza, Allen Tushabe, Mathias Akugizibwe, David Bitira, Innocent Mwesigye, Stella Kentusi, Henry Zakumumpa, Japheth Kwiringira, Merian Natukwatsa Musinguzi

“…Members developed lasting friendships and networks of support which helped them to meet the material and psychological needs of children. The VSLA groups provided safe spaces for caregivers to share challenges and to learn more about HIV prevention and treatment from expert clients which improved the care for children living with HIV. …”
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Chronic enteropathy in dogs affects the quality of life in both dogs and their owners—are veterinarians proficient in handling the caregiver burden? by Janne Graarup-Hansen Lyngby, Lise Nikolic Nielsen, Stine Ankerkilde, Amanda Wissendorf Bentzen, Charlotte Bjørnvad, Thomas Bøker Lund, Peter Sandøe, Peter Sandøe

“…Providing owners with written material about the condition in addition to medical and feeding regimen instructions may help the owner, improve compliance, and decrease the non-billable hours the veterinarian must spend communicating with the owner about their dog’s CE.…”
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iMulch: an investigation of the influence of polymers on a terrestrial ecosystem using the example of mulch films used in agriculture by Carmen Wolf, Mike Wenzel, Björn Fischer, Ralf Bertling, Erich Jelen, Dieter Hennecke, Karlheinz Weinfurtner, Martina Roß-Nickoll, Henner Hollert, Antonia Weltmeyer, Kristina Bitter, Pauline Ruiz, Dusica Banduka, Jochen Tuerk, Lars M. Blank

“…For this purpose, a minimum lower limit for the material thickness should be defined. Graphical Abstract…”
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Unambiguous identification of fungi: where do we stand and how accurate and precise is fungal DNA barcoding? by Robert Lücking, M. Catherine Aime, Barbara Robbertse, Andrew N. Miller, Hiran A. Ariyawansa, Takayuki Aoki, Gianluigi Cardinali, Pedro W. Crous, Irina S. Druzhinina, David M. Geiser, David L. Hawksworth, Kevin D. Hyde, Laszlo Irinyi, Rajesh Jeewon, Peter R. Johnston, Paul M. Kirk, Elaine Malosso, Tom W. May, Wieland Meyer, Maarja Öpik, Vincent Robert, Marc Stadler, Marco Thines, Duong Vu, Andrey M. Yurkov, Ning Zhang, Conrad L. Schoch

“…Important strategies to improve molecular identification of fungi are: (1) broadly document intraspecific and intragenomic variation of barcoding markers; (2) substantially expand sequence repositories, focusing on undersampled clades and missing taxa; (3) improve curation of sequence labels in primary repositories and substantially increase the number of sequences based on verified material; (4) link sequence data to digital information of voucher specimens including imagery. …”
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The Safety and Efficacy of the Repeated PRRT with [90Y]Y/[177Lu]Lu-DOTATATE in Patients with NET by Anna Zemczak, Paweł Gut, Dariusz Pawlak, Maciej Kołodziej, Leszek Królicki, Beata Kos-Kudła, Marek Ruchała, Grzegorz Kamiński, Jolanta Kunikowska

“…The study aims to evaluate the safety, efficacy, and progression-free survival (PFS) of patients after retreatment (R-PRRT) and re-retreatment (RR-PRRT) with tandem isotopes [90Y]Y/[177Lu]Lu-DOTATATE. Material and Methods. Out of 99 treated patients with G1 and G2 NETs, 26 were included in the study and treated with the repeated PRRT (with 5 undergoing the re-repeated PRRT treatment) after an initial positive response to four PRRT cycles and later progression of the disease. [68Ga]Ga-DOTATATE PET/CT and CT/MRI procedures were performed before and after the treatment. …”
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Comunicado de imprensa como indicador de atenção social qualificada da ciência: a construção de um banco de dados e suas potencialidades by Germana Barata, Monique Oliveira, Thaís Peixoto, Carlos Caetano de Almeida, Alysson Fernandes Mazoni, Rodrigo Costas Comesana, Juan Pablo Alperin

“…Enquanto o comunicado de imprensa não é a única forma de qualificar e entender a atenção social da ciência, a construção do banco de dados e testes realizados demonstram que se trata de um material relevante nessa compreensão.…”
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Prevalencia de anomalías dentarias en pacientes pediátricos de Kavanayén, Bolívar - Venezuela by Sofía D'Amore Noda, Karina Violeta Lahoud El Hachem, María Valentina Mirabal Bucci, Luis Manuel Acosta González, Victoria Alejandra Díaz Marcano, Valeria José De Sousa Lares, Andreina Miró Zambrano, Aida Carolina Medina Díaz

“…Bolívar - Venezuela. Material y métodos: Se realizó una investigación de tipo descriptivo, de campo, diseño transversal. …”
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A simple and efficient method to extract polar metabolites from guar leaves (Cyamopsis tetragonoloba (L.) Taub.) for GC-MS metabolome analysis by S. B. Teplyakova, A. L. Shavarda, T. V. Shelenga, E. A. Dzyubenko, E. K. Potokina

“…Another method of sample preparation is based on the short-term methanol extraction of metabolites from frozen and homogenized material. The advantages and disadvantages of these two methods revealed in the course of our work have prompted us to develop a new approach that avoids some difficulties in analyzing the metabolic profiles of leaves of various guar varieties. …”
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Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This study aims to assess the impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients.Design A pre–post cohort study.Setting Outpatient department of a tertiary care hospital affiliated with Quaid-i-Azam University, Pakistan.Participants Approximately 265 adult asthmatic patients selected through a spirometry process, aged ≥18 years, were approached. 240 patients gave consent to participate in the study and were divided into control and treatment groups.Interventions The educational intervention consisted of individual patient counselling using educational material with time varied according to each patient’s comprehension and previous knowledge.Primary and secondary outcome measures Assessment consisted of a 14-item Asthma Self-Management Knowledge Questionnaire (ASMQ) quantifying a patient’s self-management knowledge through an ASMQ score and its change following an educational intervention.Results Disease self-management knowledge was low with an average raw ASMQ score of 4.1 (max 14); which equates to a transformed score of 29.34 (max 100) and the proportion of patients who correctly answered more than 50% of questions were 16.7% preintervention. …”
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Conocimiento del riesgo cardiovascular y consumo de sal/sodio en estudiantes de ciencias de la salud by Olga Giovanna Valderrama-Rios, Anabel Roxana Aguayo-Cabana, Eva Patricia Hiyo-Huapaya, Zora María de Los Ángeles Riojas-Yance, Luci Tani Becerra-Medina, Judit Salazar-Rojas, Segundo Ignacio Ponte-Valverde, Silvia Elizabet Reyes-Narvaez

“… Objetivo: Determinar la relación entre el nivel de conocimiento del riesgo cardiovascular y la ingesta de sal/sodio en alumnos de ciencias de la salud. Material y métodos: Se realizó un estudio descriptivo, correlacional y transversal en una muestra de 288 alumnos de enfermería de una universidad privada en el distrito de Los Olivos, en Lima. …”
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Antiganglioside Antibodies and Inflammatory Response in Cutaneous Melanoma by Corina Daniela Ene, Mircea Tampa, Ilinca Nicolae, Cristina Iulia Mitran, Madalina Irina Mitran, Clara Matei, Ana Caruntu, Constantin Caruntu, Simona Roxana Georgescu

“…The aim of the study was to characterize the relation between antiganglioside antibodies and inflammation in cutaneous melanoma focusing on gangliosides GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b. Material and Method. We performed an observational study that included 380 subjects subdivided into three groups: patients with metastatic melanoma (170 cases), patients with primary melanoma (160 cases), and healthy subjects (50 subjects). …”
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Microsatellite instability and somatic gene variant profile in solid organ tumors by Ibrahim Halil Erdogdu, Seda Orenay-Boyacioglu, Olcay Boyacioglu, Nesibe Kahraman-Cetin, Habibe Guler, Merve Turan, Ibrahim Meteoglu

“…This study aimed to determine the MSI status, MMR protein expression, and somatic mutation profile in solid organ tumors. Material and methods In this study, the records of 192 patients with solid organ tumors who were referred to the Molecular Pathology Laboratory between January 2018 and December 2022 were reviewed retrospectively. …”
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Circulatory Immune Cells in Cushing Syndrome: Bystanders or Active Contributors to Atherometabolic Injury? A Study of Adhesion and Activation of Cell Surface Markers by Gloria Aranda, Cristina Lopez, Rebeca Fernandez-Ruiz, Yaiza Esteban, Guillermo Garcia-Eguren, Mireia Mora, Irene Halperin, Gregori Casals, Joaquim Enseñat, Felicia A. Hanzu

“…To investigate adhesion and activation surface cell markers (CDs) of peripheral IMNC in endogenous Cushing syndrome (CS) and the immune modulator role of ACTH. Material and Methods. 16 ACTH-dependent CS (ACTH-D), 10 ACTH-independent (ACTH-ID) CS, and 16 healthy controls (C) were included. …”
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MODELO MATEMÁTICO PARA EL CONTROL DEL CONTENIDO DE SACAROSA EN BAGAZO EN EL PROCESO DE FABRICACIÓN DE AZÚCAR by Jonathan Serrano Febles, Jesús Luis Orozco, Osney Pérez Ones, Julio César Peña

“…El procedimiento que se emplea es de gran utilidad como material metodológico para el desarrollo y evaluación de modelos de regresión lineal en la investigación operacional. …”
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Refinement of a meaning-centered counseling program for Chinese patients with advanced cancer: integrating cultural adaptation and implementation science approaches by Florence Lui, Qingyi Zhang, George Chengxi Bao, Bharat Narang, Ruo Yan Chen, Yunshan Niu, Jennifer Leng, William Breitbart

“…Conclusion Recommendations for next steps include increasing the MCP-Ch protocol’s flexibility and adaptability to allow interventionists to flexibly tailor MCP-Ch material to meet patients’ individual needs, simplifying content to improve comprehension and acceptability, providing additional training to Chinese-serving providers to increase adoption and sustainability, and considering interpreter-assisted delivery to increase access. …”
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