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35941
Myocardial Infarction-Associated Shock: A Comprehensive Analysis of Phenotypes, SCAI Classification, and Outcome Assessment
Published 2025-01-01“…This study aimed to analyze the clinical, historical, instrumental, and laboratory characteristics of the primary phenotypes of MI-CS, stratified according to the Society for Cardiovascular Angiography and Interventions (SCAI) shock severity scale. <i>Materials and Methods</i>: In this single-center, retrospective observational study, we reviewed the medical records of 1289 patients admitted to the emergency cardiology department from 1 January to 12 December 2020. …”
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35942
Ascorbic acid-containing compound efficacy in ischemic brain damage
Published 2024-09-01“…The aim: to assess anti-ischemic activity of 3-hydroxypyridine ascorbate in the in vitro and in vivo models of brain cell and tissue response to ischemia and reoxygenation. Materials and Methods: 3-hydroxypyridine ascorbate (laboratory code 3-EA) was assessed as chemical substance (purity 99.8%) diluted in sterile phosphate-buffered saline. …”
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35943
The Importance of Discordant Follicle Stimulating Hormone and Inhibin B Levels in Primary Infertile Men: Findings from a Cross-Sectional Study
Published 2025-01-01“…Purpose: We aimed to investigate the relationship between follicle stimulating hormone (FSH) and inhibin B (InhB). Materials and Methods: Data from 1,230 consecutive men presenting for primary couple’s infertility were analyzed. …”
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35944
Descripción clínica y genética de pacientes con enfermedad granulomatosa crónica en un hospital pediátrico
Published 2024-12-01“…Caracterizar clínica y genéticamente cuatro pacientes con enfermedad granulomatosa crónica del Hospital Infantil de México Federico Gómez. Material y métodos. Los pacientes con diagnóstico de enfermedad granulomatosa crónica diagnosticados por la técnica de oxidación de dihidrorrodamina, fueron caracterizados molecular y genéticamente mediante la medición de la expresión de las subunidades de la NADPH oxidasa, y por secuenciación y análisis de exoma. …”
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35945
Examining the therapeutic potential and side effects of calcium channel blockers in mortality and morbidity of patients with stroke: A systematic review of pre-clinical and clinica...
Published 2025-06-01“…Objectives: This study's primary goal is to evaluate the effects of calcium channel blockers on reducing the risk, mortality, morbidity, and long-term outcomes of cerebrovascular events. Material and Methods: We conducted this systematic literature review by searching PubMed, Scopus, and Google Scholar databases. …”
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35946
Fasting for male fertility—a mixed methods study
Published 2025-01-01“…This study aimed at investigating feasibility and effects of a Fasting Mimicking Diet (FMD) in the context of male subfertility.Materials and methodsIn this two-arm, randomized, controlled, exploratory mixed methods study men with impaired sperm quality were randomized into a fasting and a waiting-list control group. …”
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35947
Intrathecal Clonidine versus Dexmedetomidine as Adjuvants to Hyperbaric Ropivacaine in Lower Limb Orthopaedic Surgeries: A Randomised Clinical Study
Published 2025-02-01“…Aim: To compare clonidine and dexmedetomidine as adjuvants to hyperbaric ropivacaine given intrathecally in lower limb orthopaedic surgeries, focusing on haemodynamic changes, sedation, duration of analgesia, and sensory and motor blockades. Materials and Methods: This randomised clinical study was conducted in a teritary care facility at the Operation Theatre (OT) complex in the Department of Anaesthesiology at Dhiraj Hospital, Smt. …”
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35948
Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals
Published 2025-01-01“…After adjusting for potential confounding factors, compared to participants with consistently low TyG-BMI levels, those with moderate TyG-BMI levels and a slowly increasing trend had an HR of 1.27 (95% CI 1.10-1.47), while those with the highest TyG-BMI levels and a slowly decreasing trend had an HR of 1.52 (95% CI 1.26-1.83).ConclusionMaterial changes in the TyG-BMI are independently associated with the risk of CVDs in middle-aged and elderly individuals. …”
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35949
The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT
Published 2024-06-01“…The purpose of this study was to assess the impact of preliminary hydration of patients on [18F]PSMA‑1007 uptake in the urinary bladder.Materials and methods. Prospective, multicenter, randomized controlled study included 180 patients with PCa who underwent [18F]PSMA‑1007 PET/CT. …”
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35950
Clinical Characteristics of Fulminant Type 1 Diabetes Compared with Typical Type 1 Diabetes: One-Year Follow-Up Study from the Guangdong T1DM Translational Medicine Study
Published 2020-01-01“…This study was aimed at exploring the clinical features through one-year follow-up. Methods and Materials. Patients with T1DM finishing at least one-year follow-up from June 2011 to July 2018 were enrolled from Guangdong Type 1 Diabetes Translational Medicine Study. …”
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35951
Evaluation of Common and Atypical Clinical Presentations of Tinea Faciei: A Cross-sectional Study from Barabanki, Uttar Pradesh, India
Published 2025-01-01“…Aim: To enrich our understanding of tinea faciei with the intention of improving diagnostic accuracy and treatment outcomes. Materials and Methods: The present cross-sectional study was conducted in the Department of Dermatology, Venereology and Leprosy, Hind Institute of Medical Sciences, Barabanki, Uttar Pradesh, India, from October 2022 to October 2023. …”
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35952
Artificial Intelligence in Diagnostic Breast Ultrasound: A Comparative Analysis of Decision Support Among Radiologists With Various Levels of Expertise
Published 2025-01-01“…Objective: To investigate integrating an artificial intelligence (AI) system into diagnostic breast ultrasound (US) for improved performance. Materials and Methods: Seventy suspicious breast mass lesions (53 malignant and 17 benign) from seventy women who underwent diagnostic breast US complemented with shear wave elastography, US-guided core needle biopsy and verified histopathology were enrolled. …”
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35953
On the issue of creating an algorithm for assessing safety culture in modern healthcare institutions
Published 2024-06-01“…Expert assessment maps of the leading components of safety culture served as the material of the conducted research. The organizational and target structure of the scientific work provided for the determination of the structural features of the leading components of safety culture and the development of a scoring scale for their assessment, the implementation of an expert evaluation of the specified components and the establishment of the degree of consistency of the opinions of experts, the calculation of the weighting coefficients of the influence of various components on the formation of a certain level of safety culture and the justification of objective statistical approaches to assessing the level of safety culture. …”
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35954
Dynamics of cortisol levels and the state of vitamin D supply during the full-scale war in Ukraine in patients with type 2 diabetes mellitus
Published 2024-11-01“…The aim of the study was to evaluate the dynamics of the stress hormone cortisol and the state of vitamin D supply in patients with T2DM during the full-scale war in Ukraine compared to the pre-war state. Materials and methods. In 2021–2024, a prospective study was conducted, which included patients with T2DM and a glycated hemoglobin (HbA1c) level ≥ 7 %, individuals with insulin resistance without DM and people without DM aged 19–75 years. …”
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35955
Dexmedetomidine versus Dexamethasone as Perineural Adjuvants in Supraclavicular Brachial Plexus Block: An Interventional Study
Published 2025-02-01“…Aim: To compare the effects of perineural dexamethasone versus perineural dexmedetomidine added to a local anaesthetic mixture in supraclavicular brachial plexus block for upper limb surgeries. Materials and Methods: This interventional study was conducted in the Department of Anaesthesiology at Dhiraj Hospital, Vadodara, Gujarat, India from October 2023 to April 2024 on 80 patients with American Society of Anaesthesiologists (ASA) physical status I and II, aged 18 to 65 years, scheduled for surgery under supraclavicular brachial plexus block. …”
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35956
Prevalence of carbapenemase-encoding genes carriage in patients admitted to multidisciplinary hospital in Moscow
Published 2024-09-01“…To investigate the prevalence of carbapenemase-encoding genes carriage in patients at hospital admission. Materials and Methods. The prospective single-center cross-sectional study was performed in Moscow Multidisciplinary Clinical Center «Kommunarka» from 15.09.2022 till 15.08.2023. …”
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35957
Comparative microbial metagenomic analysis of drinking water plants and wastewater treatment plants in Istanbul
Published 2025-01-01“…DNA isolation was conducted using filter material, followed by sequencing on a NovaSeq 6000 instrument. …”
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35958
Dexmedetomidine versus Dexamethasone as an Adjuvant to Ropivacaine in Transversus Abdominis Plane Block in Infraumbilical Surgeries for Postoperative Analgesia: A Randomised Clinic...
Published 2025-01-01“…The secondary objective was to compare postoperative haemodynamic changes and side effects. Materials and Methods: In this randomised double-blinded prospective clinical study, conducted in the Department of Anaesthesia, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (SBKS MIRC), Piparia, Vadodara, Gujarat, India from March 2023 to September 2024. 80 patients of American Society of Anaesthesiologists (ASA) I and II, aged 18-60 years, undergoing elective infraumbilical surgeries (open abdominal hysterectomy and open bilateral inguinal hernia repair) under spinal anaesthesia were randomly allocated into two groups of 40 patients each. …”
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35959
Intervención en acondicionamiento físico en adultos mayores para realizar cambios en estados de prefragilidad y fragilidad
Published 2025-01-01“…Objetivo: Evaluar el estado de prefragilidad y fragilidad después de la intervención de actividad física en el síndrome de prefragilidad en el adulto mayor de la unidad medico familiar número 6 del instituto mexicano del seguro social en Puebla Material y métodos: Se realizó un estudio cuasiexperimental, comparativo,prospectivo, transversal, unicentrico. …”
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35960
Assessment of various etiological factors for oral squamous cell carcinoma in non-habit patients- a cross sectional case control study
Published 2025-01-01“…The aim was to assess Harvey Rat Sarcoma Virus gene (HRAS) mutation, total bacterial count, Herpes Simplex Virus-1 (HSV-1), regressive changes of teeth, total antioxidant capacity and its association with NHOSCC. Materials and methods A total of 564 (n = 564) patients with OSCC were included in the study. …”
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