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Longitudinal impact of cross-clamp duration on postoperative sleep disturbance and quality of life in elderly cardiac surgery patients: a secondary analysis of the MINDDS trial
Published 2025-01-01“…ObjectivesThis study aimed to assess the enduring impact of cross-clamp duration on postoperative sleep disturbance and functional outcomes (up to 180 days) in cardiac surgery patients.DesignThis is a secondary analysis of data from a randomized, double-blind trial comparing dexmedetomidine to placebo for delirium prevention (Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep).SettingData from patients recruited at a tertiary medical center in Boston, Massachusetts, between March 2017 and February 2022 were analyzed in January 2024.ParticipantsThe study included 394 patients aged ≥60 who underwent cardiac surgery with cardiopulmonary bypass.InterventionsThe primary exposure was cross-clamp time, while secondary exposures included surgical type [isolated coronary artery bypass graft (CABG) or not] and dexmedetomidine randomization.Measurements and main resultsThe primary outcome was sleep quality, assessed using the PROMIS Sleep Disturbance questionnaire at 30, 90, and 180 days postoperatively. …”
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A Role of Three-Dimensional (3D)-Reconstruction in the Classification of Lung Adenocarcinoma
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Investigating the Applicability of the Peak Density Thickness Parameter over the Equatorial Region
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Tuning Wetting Properties Through Surface Geometry in the Cassie–Baxter State
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Malnutrition risk, weight loss, and subsequent survival in patients listed for heart transplantation
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Reshaping Our Understanding of Sensation and Pain Following Breast Reduction Surgery
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