-
1721
Emerging Resistance and Virulence Patterns in <i>Salmonella enterica</i>: Insights into Silver Nanoparticles as an Antimicrobial Strategy
Published 2025-01-01“…Methods: In 2019, community-acquired <i>Salmonella</i> strains were collected and identified using MALDI-TOF mass spectrometry, antibiotic susceptibility profiles have been determined with the MicroScan system, and soluble virulence factors were evaluated using specific culture media, while biofilm formation was quantified in 96-well plates. …”
Get full text
Article -
1722
花椒油中邻苯二甲酸酯类塑化剂的污染现状 及来源分析Pullution status and source analysis of phthalate plasticizers in Zanthoxylum bungeanum oil
Published 2025-01-01“…The contents of dibutyl phthalate (DBP) and bis(2-ethylhexyl)phthalate (DEHP) in 92 Zanthoxylum bungeanum oil samples were determined by gas chromatography-mass spectrometry and their pollution sources were analyzed. …”
Get full text
Article -
1723
How Antiretroviral Drug Concentrations Could Be Affected by Oxidative Stress, Physical Capacities and Genetics: A Focus on Dolutegravir Treated Male PLWH
Published 2025-01-01“…Drug concentrations and oxidative stress biomarkers levels were evaluated through liquid chromatography coupled with tandem mass spectrometry, while genetic variants through real-time PCR. …”
Get full text
Article -
1724
Super-enhancers and efficacy of triptolide in small cell carcinoma of the ovary hypercalcemic type
Published 2025-02-01Get full text
Article -
1725
Oxidized phospholipid and transcriptomic signatures of THC-related vaping associated lung injury
Published 2024-12-01“…BALF samples were analyzed by Luminex multiplex assay, RNA sequencing, and mass spectrometry. After treating BEAS-2B lung epithelial cells with vaping and non-vaping BALF, LDH release was quantified. …”
Get full text
Article -
1726
Cross-sectional and longitudinal associations between serum vitamin D and continuous metabolic syndrome score among children and adolescents: roles of levels of inflammation in per...
Published 2025-01-01“…Serum 25(OH)D concentrations were quantified using liquid chromatography-mass spectrometry. Continuous Metabolic syndrome risk score (CMSRS), incorporating waist, blood pressure, blood lipid levels, and glucose metabolism as four components, utilizes age- and gender-specific Z scores to evaluate metabolic risk. …”
Get full text
Article -
1727
A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity
Published 2025-01-01“…To investigate the molecular alterations in the mice’s brains, untargeted metabolomics and label-free Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) were employed. Subsequently, Western blot (WB) and quantitative reverse transcription PCR (RT-qPCR) techniques were utilized to detect specific molecular changes induced by [D1G, ΔQ14] LvIC.ResultsThe injection of [D1G, ΔQ14] LvIC led to a decrease in locomotor activity in mice. …”
Get full text
Article -
1728
Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater
Published 2021-01-01“…The method includes enrichment and clean-up steps by solid phase extraction using mix-mode cation exchange, followed by identification and quantification using an ultrahigh-performance liquid chromatography and tandem mass spectrometry and employing electrospray ionization (UPLC-ESI-MS/MS). …”
Get full text
Article -
1729
Multi-omics dissection of metabolic dysregulation associated with immune recovery in people living with HIV-1
Published 2025-01-01“…Methods In this cross-sectional study, mass spectrometry was used for quantitative analysis of plasma metabolome and lipidome in 24 treatment-naïve PLWH (TNs), 33 immunological responders (IRs), 35 immunological non-responders (INRs), and 16 healthy controls (HCs). …”
Get full text
Article -
1730
Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation
Published 2025-02-01“…This study was aimed to discern unique metabolite signatures in obese and lean individuals using liquid chromatography-mass spectrometry quadruple time-of-flight (LC-MS/Q-TOF), with the goal of elucidating their roles in obesity. …”
Get full text
Article -
1731
IQUB mutation induces radial spoke 1 deficiency causing asthenozoospermia with normal sperm morphology in humans and mice
Published 2025-01-01“…Computer-aided sperm analysis, Papanicolaou staining, and electron microscopy were applied to evaluate the motility, morphology, and ultrastructure of spermatozoa, respectively. Protein mass spectrometry, western blotting, and bioinformatic analyses were performed to identify critical components of mammalian RS1 to model its structure and explore the pathological mechanism of IQUB deficiency. …”
Get full text
Article -
1732
Effects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath
Published 2025-01-01“…We collected venous blood samples before and after (5 min and 30 min) the ice baths to measure hormones (noradrenaline, adrenaline, and cortisol) and lipid levels in plasma via liquid chromatography mass spectrometry shotgun lipidomics. We found that ice baths in the morning increase plasma fatty acids more than in the evening. …”
Get full text
Article -
1733
Monitoring the Concentrations of Na, Mg, Ca, Cu, Fe, and K in <i>Sargassum fusiforme</i> at Different Growth Stages by NIR Spectroscopy Coupled with Chemometrics
Published 2025-01-01“…Currently, the determination of minerals in <i>S. fusiforme</i> primarily relies on inductively coupled plasma mass spectrometry and other methods, which are time-consuming and labor-intensive. …”
Get full text
Article -
1734
Proteomic Analysis of Hypoxia-Induced Senescence of Human Bone Marrow Mesenchymal Stem Cells
Published 2021-01-01“…Tandem mass tag (TMT) labeling was combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for differential proteomic analysis of hypoxia in hBMSCs. …”
Get full text
Article -
1735
Effect of Rifaximin and a Multi-Strain Probiotic on the Intestinal Microbiome and Cardiovascular Risk Indicators in Patients with Coronary Heart Disease
Published 2019-09-01“…TMAO concentration was determined using liquid chromatography–mass spectrometry. To study the composition of fecal microflora, 16S sequencing was used followed by a graphical representation of the results. …”
Get full text
Article -
1736
Hydrocarbon generation, expulsion, and retention characteristics of the Permian Fengcheng shale and Lucaogou shale in the Junggar Basin: implications for the exploration of lacustr...
Published 2025-01-01“…This study establishes hydrocarbon generation patterns for the Fengcheng shale and Lucaogou shale using a semi-open thermal simulation system, combined with rock pyrolysis, vitrinite reflectance (Ro), total organic carbon (TOC) analysis, carbon isotope analysis, gas chromatography-mass spectrometry (GC-MS), mercury porosimetry, and nitrogen adsorption. …”
Get full text
Article -
1737
Association between alkali and alkaline earth elements in chorionic villus and risk for spontaneous abortion
Published 2025-01-01“…The concentrations of six alkali and alkaline earth elements in chorionic villi were measured using inductively coupled plasma mass spectrometry (ICP-MS). Through using logistic regression, Bayesian kernel machine regression (BKMR) and Weighted quantile sum regression (WQS) model, we assessed single and mixed exposure effects of alkali and alkaline earth elements on spontaneous abortion. …”
Get full text
Article -
1738
Hu-lu-su-pian ameliorates hepatic steatosis by regulating CIDEA expression in AKT-driven MASLD mice
Published 2025-01-01“…This study aimed to explore the therapeutic potential of HLSP on MASLD and the underlying mechanism.MethodsThe researchers used ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS) to identify the primary chemical components of HLSP. …”
Get full text
Article -
1739
YWHAG promotes bladder cancer metastasis by regulating TMOD3 to activate ERK1/2 and JNK phosphorylation in the MAPK pathway
Published 2024-12-01“…The interaction between YWHAG and TMOD3 (Tropomodulin 3) was confirmed through pull-down assays coupled with mass spectrometry, co-immunoprecipitation (Co-IP), and cell immunofluorescence studies. …”
Get full text
Article -
1740
Identification of Host–Protein Interaction Network of Canine Parvovirus Capsid Protein VP2 in F81 Cells
Published 2025-01-01“…In this study, 140 host proteins specifically binding to CPV VP2 protein were identified by immunoprecipitation combined with liquid chromatography–mass spectrometry (LC-MS/MS). Subsequently, the protein Interaction Network (PPI), the annotation of gene ontology (GO) and the database of Kyoto Encyclopedia of Genes and Genomes (KEGG) were constructed for in-depth analysis. …”
Get full text
Article