Association of breast milk microbiota and metabolites with neonatal jaundice by TianYu Liu, TianYu Liu, Yanhan Yuan, Jinying Wei, Jinying Wei, Jiayi Chen, Feng Zhang, Feng Zhang, Juanjuan Chen, Jinping Zhang

“…Breast milk samples were collected from mothers in both groups on postnatal day 4 and analyzed for microbiota and small-molecule metabolites using 16S rRNA gene sequencing and an liquid chromatography-tandem mass spectrometry techniques.ResultsA total of 104 mother-child pairs were included in the study, of which 51 pairs were in the healthy control group and the other 53 pairs were in the jaundice group. …”
Get full text

Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris by Sibel Kalyoncu, Dogu Sayili, Ayca Zeybek Kuyucu, Hakan Soyturk, Seyda Gullu, Busra Ersayan, Ibrahim Oguzhan Tarman, Mehmet Ender Avci, Olcay Mert, Umut Haskok, Ege Tekin, Huseyin Akinturk, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Ceren Ulker, Bilgi Gungor, Mehmet Inan

“…After in vitro characterisation of purified RBD‐Omicron via chromatography, mass spectrometry, calorimetry and surface plasmon resonance‐based methods, it was injected into mice for immunization studies. …”
Get full text

HnRNPM modulates alternative splicing in germ cells by recruiting PTBP1 by Peng Lv, Wenchao Xu, Sheng Xin, Yuanxuan Deng, Bin Yang, Dengjianyi Xu, Jian Bai, Deilin Ma, Tao Wang, Jihong Liu, Xiaming Liu

“…Coimmunoprecipitation and mass spectrometry analyses revealed the proteins that interact with hnRNPM. …”
Get full text

Mechanism of Mongolian Medicine Batri-7 on Salmonella Enteritis by Yang D, Chen S, Borijihan H, Aoqier A, Sarula S, Siqin S, Manda M, Temuqile T, Baigude H

“…This study explores BT-7’s antibacterial compounds and therapeutic mechanism in a Salmonella enteritis mouse model.Methods: The active components of BT-7 were detected by liquid chromatography-tandem mass spectrometry assay and identified by UPLC/Q-TOF-MS. …”
Get full text

Physical and Chemical Properties of Biodiesel Obtained from Amazon Sailfin Catfish (Pterygoplichthys pardalis) Biomass Oil by F. Anguebes-Franseschi, A. Bassam, M. Abatal, O. May Tzuc, C. Aguilar-Ucán, A. T. Wakida-Kusunoki, S. E. Diaz-Mendez, L. C. San Pedro

“…The physical and chemical properties of biofuel produced were evaluated under the specifications of the European standard EN-14214 by using gas chromatography-mass spectrometry, infrared spectroscopy, and atomic absorption spectrometry analyses. …”
Get full text

Legacy and emerging organic pollutants in indoor and outdoor environments in Africa: Contamination levels, health risks, and analytical techniques by Godfrey Muhwezi, Christine Kyarimpa, Ivan Gumula, Christine Betty Nagawa, Solomon Omwoma, Henry Matovu, Julius Matsiko, Silver Odongo, Douglas Sifuna, Ivan Špánik, Charles Drago Kato, Patrick Ssebugere

“…Gas Chromatography and mass spectrometry were the most frequently used analytical techniques for both air and dust probably due to their sensitivity and selectivity in detecting chemical traces at the pg m−3 and ng g−1 levels. …”
Get full text

An exploratory analysis of differences in serum protein expression by sex in patients with systemic sclerosis associated interstitial lung disease by Giuliana Cerro-Chiang, Matthew Ayres, Alejandro Rivas, Sarah J. Parker, Mitra Mastali, Peter Chen, Jennifer E. Van Eyk, Paul J. Wolters, Francesco Boin, Tanzira Zaman

“…Methods Serum specimens of patients with SSc-ILD underwent dual mass spectrometry (LC-MS/MS) analysis. The association between protein biomarkers and sex was assessed through logistic regression. …”
Get full text

Phytochemical and Biological Investigations of Crude Extracts of <i>Astragalus pisidicus</i> by Esra Aydemir, Elif Odabaş Köse, Serap Özkaya Gül, Alaaddin Korkut, A. Cansu Kilit, Mehmet Engin Celep, Mustafa Yavuz, R. Süleyman Göktürk, Cengiz Sarikurkcu

“…<b>Methods</b>: The water and methanolic fractions of four parts (stems, flowers, leaves, root) as well as the whole plant were quantified and identified by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC–ESI–MS/MS) analysis. Cell death was assessed using the WST-1 assay, while apoptosis was identified by colorimetric protease assay for caspase 2, -3, -6, -8, and -9, as well as cellular DNA fragmentation assay. …”
Get full text

Toxicity effect of Ricinus communis methanolic extracts against Bactrocera cucurbitae (Diptera: Tephritidae) by Sadia Manzoor, Rasheed Akbar, Afaq Hussain, Amjad Ali, Brekhna Faheem, Maid Zaman, Abid Farid, Ijaz Hussain, Imtiaz Ali Khan, Kahkashan Perveen (ORCID:

“…The crude extract of R. communis was subjected to fractionating using different organic solvents in an increasing order of polarity, where the fraction indicating maximum activity was then taken for the isolation of the bioactive compounds using various chromatographic and spectroscopic techniques such as column chromatography, thin layer chromatography (TLC), gas chromatography-mass spectrometry (GC-MS). The concentrations of R. communis extracts at 0.5, 1.0, 1.5 and 2% methanol were used. …”
Get full text

Compositional changes of dissolved organic matter during high flow events in headwater catchments along a gradient of climate and land use by Jeanneau, Laurent, Fovet, Ophélie, Faucheux, Mikaël, Gruau, Gérard,  Liotaud, Marine, Pierret, Marie-Claire, Cotel, Solenn, Molénat, Jérôme,  Lagacherie, Manon, Dessert, Céline, Probst, Anne

“…The DOM composition was analyzed by thermochemolysis coupled with gas chromatography and mass spectrometry, making it possible to perform a joint analysis of several biomolecule families, monitor the proportion of compounds derived from plant inputs (%VEG) and study the lignin composition through the C/V ratio. …”
Get full text

UV-fs-LA-ICP-MS Analysis of CO2-Rich Fluid Inclusions in a Frozen State: Example from the Dahu Au-Mo Deposit, Xiaoqinling Region, Central China by Wei Jian, Moritz Albrecht, Bernd Lehmann, Jingwen Mao, Ingo Horn, Yanhe Li, Huishou Ye, Zongyan Li, Guanguan Fang, Yongsheng Xue

“…The recently developed technique of ultraviolet femtosecond laser ablation inductively coupled plasma mass spectrometry (UV-fs-LA-ICP-MS) combined with a freezing cell is expected to improve the analysis of CO2-rich fluid inclusions by decreasing their internal pressure and avoiding the common problem of uncontrolled explosive fluid release on ablation. …”
Get full text

Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB by So Who Kang, Jung-Eun Park, Soonhyuck Ok, Minhui Um, Hyeonjeong Son, Seunghee Byun, Nayoung Park, Su Jin Lee, Thị Xuân Thùy Trần, Gyeongmin Kim, Jeonghun Yeom, Kyunggon Kim, Eun Young Kim, Min-Ji Kang

“…Moreover, reducing slimb expression mitigates the effects of USP14 on PER protein stability. Mass spectrometry identifies two ubiquitination sites on PER (Lys1117 and Lys1118) critical for its degradation. …”
Get full text

Pharmacokinetics of 7,8-dihydroxyflavone in neonatal mice with hypoxia-ischemia related brain injury by Sin Yin Lim, Cameron O. Scarlett, Sefer Yapici, Peter Ferrazzano, Peter Ferrazzano, Pelin Cengiz, Pelin Cengiz

“…A liquid chromatography-tandem mass spectrometry method was developed to quantitate the drug concentration in plasma samples, as well as in samples from the left and right brain hemispheres. …”
Get full text

Synergistic antimicrobial activity of essential oils mixture of Moringa oleifera, Cinnamomum verum and Nigella sativa against Staphylococcus aureus using L-optimal mixture design by Samah H. Abu-Hussien, Antony R. Nasry, Ziad Samy, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa ElNoby

“…Gas chromatography mass spectrometry (GC/MS) identified abundant bioactive phytochemicals like cinnamaldehyde, linoleic acid, and palmitic acid methyl esters underlying the observed antimicrobial effects. …”
Get full text

Exposure to Silica, Arsenic, and Chromium (VI) in Cement Workers: A Probability Health Risk Assessment by Noor Haziqah Kamaludin, Juliana Jalaludin, Shamsul Bahri Mohd Tamrin, Abdah Md Akim, Tri Martiana, Noeroel Widajati

“…Inductively coupled plasma mass spectrometry (ICP-MS) was used for As, and Cr analysis, and X-ray powder diffraction (XRD) was used for Si analysis. …”
Get full text

Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

“…Mass Spectrometry allied with in-vivo generation of activated alloreactive T cell populations and tetramer screening facilitates the identification of endogenous peptides that are directly recognised in complex with allogeneic Major Histocompatibility class I (MHC I) molecules by alloreactive CD8+ T cells. …”
Get full text

Danlian-Tongmai formula improves diabetic vascular calcification by regulating CCN3/NOTCH signal axis to inhibit inflammatory reaction by Wenting Wang, Yiwen Li, Mengmeng Zhu, Qian Xu, Jing Cui, Yanfei Liu, Yanfei Liu, Yue Liu

“…This study aims to elucidate the effects of DLTM on DVC and explore the underlying mechanisms of action.MethodsUltra-high-performance liquid chromatography-mass spectrometry (UHPLC-MS) was used to identify the metabolites of DLTM. …”
Get full text

Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study by Li X, Liu S, Yu M, Xi W, Wu X, Liu D, Liu A, Wang H

“…Precisely quantifying their plasma levels is crucial for clinical pharmacokinetic assessments and therapeutic drug monitoring.Aim: This study aimed to establish a generic and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) assay for the determination of five PPIs (esomeprazole, rabeprazole, ilaprazole, lansoprazole, and pantoprazole) and the P-CAB (vonoprazan) in human plasma.Methods: The six analytes were extracted from human plasma via protein precipitation and a single dilution step. …”
Get full text

Reaction kinetics and molecular characterization of the compounds formed by photosensitized degradation of the plastic additive bisphenol A in the atmospheric aqueous phase by Yiting Wang, Qingxin Deng, Yiqun Wang, Pan Li, Biao Jin, Jiangping Liu, Peng Cheng, Marcello Brigante, Dario D’Antuono, Luca Carena, Hui Chen, Davide Vione, Sasho Gligorovski

“…Ultra-high resolution mass spectrometry revealed that the presence of inorganic salts (NaCl and NaBr) markedly increased the complexity of the observed CHO product compounds formed upon photosensitized degradation of BPA. …”
Get full text

Antigenicity, Solubility and Digestibility of β-Lactoglobulin Combined with Different Plant Polyphenols by Liyan NONG, Xueming LIU, Jingrong CHENG, Jinhao ZOU, Wenhong CAO, Daobang TANG, Huaigu YANG

“…Meanwhile, liquid chromatography coupled with tandem mass spectrometry indicated that gallic acid unit-based tannins (or acids), such as corilagin and ellagic acid, were dominant polyphenols in longan pericarp/seed extracts. …”
Get full text