Antibiotic Resistance and Molecular Epidemiological Characteristics of Streptococcus agalactiae Isolated from Pregnant Women in Guangzhou, South China by Zhaomin Cheng, Pinghua Qu, Peifeng Ke, Xiaohan Yang, Qiang Zhou, Kai Lan, Min He, Nannan Cao, Sheng Qin, Xianzhang Huang

“…Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) mass peak analysis was performed to discriminate the specific sequence types (STs). …”
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The effects of Thymus capitatus essential oil topical application on milk quality: a systems biology approach by Ralph Nehme, Chiara Gini, Elise Vanbergue, Sergine Even, Filippo Biscarini, Sonia Andrés, Lucie Rault, Faustine Noel, Valerie Hardit, Said Bouhallab, David M. Pereira, Riadh Ksouri, Philippe Roussel, Secundino López, Paola Cremonesi, Bianca Castiglioni, Donatella Caruso, Fiorenza Faré, Manuela Fontana, Fabrizio Ceciliani, Latifa Abdennebi-Najar

“…This study aimed to investigate the impact of Thymus capitatus essential oil (TCEO), known for its high antibacterial and antioxidant properties, on milk microbiota using 16S rRNA sequencing, the lipidomic profile via liquid chromatography-quadrupole time-of-flight mass spectrometry, udder skin microbiota, and inflammatory biomarkers of dairy cows at the end of lactation. …”
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Phytochemical Profiling, GC-MS Analysis and Antibacterial Activity of Sida acuta leave Extracts Against Helicobacter pylori by Kamoldeen Ajijolakewu, Ayobami Elias Ajadi, S A Ayoola, Sheriffdeen Issa Bale, Taiwo Ayodeji Sorunke, Saheed Abayomi Onifade, Tomisin Oyawoye

“…This research assessed the phytochemical profile, performed Gas Chromatography-Mass Spectrometry (GC-MS) analysis, and evaluated the antibacterial efficacy of Sida acuta extracts against H. pylori.  …”
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Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

“…At 1 month post-dose, we compared tissue vector genomes, mRNA, and microdystrophin-FLAG protein levels by meso-scale discovery-enzyme-linked immunosorbent assay, liquid chromatography-mass spectrometry, and immunofluorescence. The C5-12 promoter was highly selective for heart and skeletal muscles, when compared to off-target tissues such as peripheral blood mononuclear cells, lung, liver, and kidney. …”
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Effect of Baoshenfang Formula on Podocyte Injury via Inhibiting the NOX-4/ROS/p38 Pathway in Diabetic Nephropathy by Fang-qiang Cui, Long Tang, Yan-bin Gao, Yue-fen Wang, Yuan Meng, Cun Shen, Zi-long Shen, Zhi-qiang Liu, Wen-jing Zhao, Wei Jing Liu

“…In the identified compounds by mass spectrometry, some active constituents of BSF were reported to show antioxidative activity. …”
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Congenital Zika Syndrome: Insights from Integrated Proteomic and Metabolomic Analysis by Leticia Gomes-de-Pontes, Lucila Akune Barreiros, Lillian Nunes Gomes, Ranieri Coelho Salgado, Sarah Maria da Silva Napoleão, Paulo V. Soeiro-Pereira, Saulo Duarte Passos, Antonio Condino-Neto

“…<b>Methods:</b> We conducted advanced proteomic and metabolomic analyses using mass spectrometry for protein and metabolite identification. …”
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A Study of Volatile Organic Compounds in Patients with Obstructive Sleep Apnea by Chuan Hao Gui, Zhunan Jia, Zihao Xing, Fuchang Zhang, Fang Du, Alex Chengyao Tham, Ming Yann Lim, Yaw Khian Chong, Agnes Si Qi Chew, Khai Beng Chong

“…<b>Objectives</b>: This study explores the potential of proton-transfer-reaction mass spectrometry (PTR-MS) in identifying volatile organic compound (VOC) biomarkers for the non-invasive detection of OSA. …”
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Plasma prolactin axis shift from placental to pituitary origin in late prepartum mice by Taku James Sairenji, Shinnosuke Masuda, Yuya Higuchi, Mitsue Miyazaki, Hiroyuki Yajima, Oh Kwan Ee, Yuki Fujiwara, Takuya Araki, Noriaki Shimokawa, Noriyuki Koibuchi

“…To investigate this hypothesis and to seek proteomic changes, we performed a shotgun proteome analysis of the placental tissue using data-independent acquisition mass spectrometry (DIA-MS). Up to 5,891 proteins were identified, including 17 PRL family members. …”
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Characterization of microbial communities in flavors and fragrances during storage by Yingjie Feng, Tingting Zhang, Jinchu Yang, Wenzhao Liu, Yongfeng Yang, Jihong Huang, Shen Huang, Zongcan Yang, Qianjin Liu, Wenchao Zheng, Qing Zhou, Qing Zhou

“…Gas chromatography–mass spectrometry (GC–MS) analysis revealed significant degradation of key aromatic compounds, such as 5-hydroxymethylfurfural (5-HMF), vanillin, and its derivative ethyl vanillin. …”
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Contrasting seasonal patterns in particle aggregation and dissolved organic matter transformation in a sub-Arctic fjord by M. G. Digernes, Y. V. Bodur, M. Amargant-Arumí, O. Müller, J. A. Hawkes, S. G. Kohler, U. Dietrich, M. Reigstad, M. L. Paulsen

“…Before and after incubation, samples were collected for dissolved and particulate organic carbon concentrations (DOC, POC), extracellular polymeric substances (EPSs), microbial community (flow cytometry), and molecular composition of DOM (high-performance liquid chromatography coupled to high-resolution mass spectrometry – HPLC-HRMS). During the biologically productive period, when environmental POC concentrations were high (April, June, September), the filtered water showed an increase in POC concentrations. …”
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Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin by A. Valle, J. Sastre-Serra, C. Pol, A. M. Miró, J. Oliver, P. Roca

“…Methods: We used two-dimensional gel electrophoresis (2-DE) and matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) to identify proteins affected by leptin. …”
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Antidepressant- and Anxiolytic-like Effects in Mice of Alkaloids from Aerial Parts of <i>Argemone platyceras</i> Link & Otto by Mayra Beatriz Gómez-Patiño, Rosa Estrada-Reyes, Héctor Hugo Hernández-Mendoza, Ángela Suarez-Rojas, Daniel Arrieta-Baez

“…<b>Results:</b> AlkExt was analyzed using mass spectrometry techniques (DI-ESI and UHPLC-MS) to detect 2,3′,4,5′-Tetramethoxystilbene (<i>m</i>/<i>z</i> 301.14, 3%), scoulerine (<i>m</i>/<i>z</i> 328.16, 19.8%), tetrahydro-columbamine (<i>m</i>/<i>z</i> 342.17, 28.8%), 8-(hydroxymethyl)-2,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-1,11-diol (<i>m</i>/<i>z</i> 358.17, 22.8%), and glaucine (<i>m</i>/<i>z</i> 356.19, 11.1%); these were assayed in a single oral administration of AlkExt, which caused robust anxiolytic- and antidepressant-like effects without affecting the spontaneous ambulatory activity of the mice. …”
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PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53 by Yongli Fan, Yuqin Li, Xia Luo, Shiqi Xiang, Jia Hu, Jingchun Zhan, Weilong Chang, Rui Deng, Xianwen Ran, Yize Zhang, Yudie Cai, Weiwei Zhu, Huifen Wang, Zhibo Liu, Di Wang

“…Immunoprecipitation (IP) combined with protein mass spectrometry and Co-Immunoprecipitation (Co-IP) was used to identify p53 interacting with PTOV1. …”
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Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis by Fanxuan Zhang, Fang Wang, Lisha Zhao, Leqian Wang, Wenjing Li, Feihua Huang, Feihua Huang, Nani Wang, Nani Wang

“…Ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was applied to identify the absorbed components of YNJ.ResultsYNJ attenuated pulmonary damage in LPS-treated mice, as evidenced by reduced protein content in bronchoalveolar lavage fluid, decreased lung wet/dry weight ratio, and improved respiratory function. …”
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Multilevel plasticity and altered glycosylation drive aggressiveness in hypoxic and glucose-deprived bladder cancer cells by Andreia Peixoto, Dylan Ferreira, Andreia Miranda, Marta Relvas-Santos, Rui Freitas, Tim S. Veth, Andreia Brandão, Eduardo Ferreira, Paula Paulo, Marta Cardoso, Cristiana Gaiteiro, Sofia Cotton, Janine Soares, Luís Lima, Filipe Teixeira, Rita Ferreira, Carlos Palmeira, Albert J.R. Heck, Maria José Oliveira, André M.N. Silva, Lúcio Lara Santos, José Alexandre Ferreira

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Isoniazid urine spectrophotometry for prediction of serum pharmacokinetics in adults with TB by P. S. Rao, K. Reed, N. Modi, D. Handler, K. Petros de Guex, S. Yu, L. Kagan, R. Reiss, N. Narayanan, C. A. Peloquin, A. Lardizabal, C. Vinnard, T. A. Thomas, Y. L. Xie, S. K. Heysell

“…Dose adjustment can be personalized by measuring peak serum concentrations; however, the process involves cold-chain preservation and laboratory techniques such as liquid chromatography (LC)/mass spectrometry (MS), which are unavailable in many high-burden settings. …”
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Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid by Yanqing Xia, Hongwu Tian, Yanlei Li, Xinru Yang, Jinming Liu, Chunli Liu, Li Zhou, Lincai Zhang, Tiejian Li, Tiesheng Shi

“…A general reaction stoichiometry of Δ[Pt(IV)] : Δ[Thiol]tot = 1 : 2 was revealed for all the thiols; the thiols were oxidized to their corresponding disulfides which were identified by mass spectrometry. Reaction mechanisms are proposed which involves all the prololytic species of the thiols attacking the Pt(IV) prodrug in parallel, designating as the rate-determining steps. …”
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Argon release, crystallization, morphological and optical changes of ion-beam sputtered Ta2O5 thin films during thermal treatments by A. Paolone, M. Bazzan, G. Favaro, F. Borondics, G. Nemeth, F. Capitani, S. Swaraj, R. Belkhou, R. Flammini, J. Teillon, C. Michel, D. Hofman, M. Granata

“…Mass spectrometry measurements at high temperatures on amorphous Ta2O5, produced by Ion Beam Sputtering (IBS) and widely used for the high reflective coatings of the mirrors of gravitational-wave detectors, detect a release of argon around 1000 K. …”
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A 1-Year Sediment Trap Study on the Downward Flux of Polycyclic Aromatic Hydrocarbons by Settling Particulate Matter in Deep Basins of the Aegean and Ionian Seas, Northeastern Medi... by Ester Skylaki, Constantine Parinos, Maria Tsagkaraki, Ioannis Hatzianestis, Anastasia Christidi, Elisavet Skampa, Ioanna Nikolopoulou, Georgia Kambouri, Ioanna Stavrakaki, Dimitris Velaoras, Giorgos Kouvarakis, Maria V. Triantaphyllou, Maria Kanakidou, Nikolaos Mihalopoulos, Alexandra Gogou

“…Sinking particles were collected using sediment traps, and PAH analysis was conducted via gas chromatography-mass spectrometry. PAH fluxes varied significantly, peaking in the north Aegean Sea due to mesotrophic conditions, nutrient-rich riverine and Black Sea water inflows, and maritime anthropogenic inputs. …”
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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report by Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa Matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto

“…We have developed a highly sensitive liquid chromatography-tandem mass spectrometry method for measuring AGEs in human serum. …”
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