Unusual open-system behaviour revealed by LA-MC-ICP-MS U–Th dating of coral and coralline algae bio-carbonates by Condomines, Michel, Bruguier, Olivier, Hajji, Inès, Zaara-Ben Mosbah, Chedia

“…This paper presents new U–Th ages obtained by LA-MC-CP-MS (laser ablation - multi-collector - inductively coupled plasma - mass spectrometry) on coral samples from a sedimentary core of the Tunis lagoon. …”
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Fatty Acids of European Sardine (<i>Sardina pilchardus</i>) White Muscle Can Discriminate Geographic Origin Along the Iberian Atlantic Coast by Ricardo Calado, Marcos Palma, Maria Rosário Domingues, Fernando Ricardo, Felisa Rey

“…While 35 FAs were identified using gas chromatography–mass spectrometry in the white muscle of <i>S. pilchardus</i>, the following, as determined by the Boruta algorithm, were key for sample discrimination: 14:0, 22:6<i>n</i>-3, 22:5<i>n</i>-3, 18:0, 20:5<i>n</i>-3, 16:1<i>n</i>-7, 16:0, and 18:1<i>n</i>-7 (in increasing order of relevance). …”
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Customization of an efficient and cost-effective optical biosensor for trace cadmium detection in milk samples by Varsha S. Pawar, Shivaji D. Pawar, Harish Mudila, Arif D. Sheikh, Ajeet Kaushik, Anil Kumar

“…., atomic absorption spectrometry (AAS), inductively coupled plasma-mass spectrometry (ICP-MS)], often require expensive equipment, extensive sample preparation or specialized expertise. …”
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Improved Risk Prediction of Acute Myocardial Infarction in Patients With Stable Coronary Artery Disease Using an Amino Acid-Assisted Model by Yi-Jing Zhao, Yong Li, Feng-Xiang Wang, Hao Lv, Yaoyao Qu, Lian-Wen Qi, Pingxi Xiao

“…Plasma amino acid levels were quantified using liquid chromatography tandem mass spectrometry (LC-MS/MS) employing a targeted metabolomics approach. …”
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Aroma profile of two commercial truffle species from Yunnan and Sichuan, China: inter- and intraspecific variability and shared key compounds by Bin Lu, Jesús Perez-Moreno, Fengming Zhang, Andrea C. Rinaldi, Fuqiang Yu

“…In this study, volatile organic compounds (VOCs) from fruiting bodies of two Chinese truffles of commercial relevance, Tuber indicum and Tuber pseudohimalayense, were analyzed using headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). We aimed to characterize the aroma profile and determine whether it would be influenced by provenance and stage of maturation. …”
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Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament by Emmajay Sutherland, Christopher J. Harding, Tancrède du Monceau de Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster

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Antioxidant and Antimicrobial Properties of Cactus Pear (Opuntia) Seed Oils by Esther Ramírez-Moreno, Raquel Cariño-Cortés, Nelly del Socorro Cruz-Cansino, Luis Delgado-Olivares, José Alberto Ariza-Ortega, Vanessa Yelina Montañez-Izquierdo, María Manuela Hernández-Herrero, Tomás Filardo-Kerstupp

“…The fatty acid profile was analyzed by gas chromatography-mass spectrometry (GC-MS). Oil from green cactus pear seeds obtained with ethanol and ethyl acetate exhibited higher antioxidant activity (p<0.05) of 323 and 316 μmol TE/20 mg (p < 0.05), respectively, compared to red cactus pear seed oil (≈274 and 247 μmol TE/20 mg with ethyl acetate and ethanol, resp.). …”
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Widely targeted metabolomics analysis reveals differences in volatile metabolites among four Angelica species by Jiaojiao Ji, Lanlan Zang, Tingting Lu, Cheng Li, Xiaoxu Han, Soo-Rang Lee, Li Wang

“…In this study, widely targeted metabolomics based on gas chromatography-tandem mass spectrometry was employed to analyze the metabolomes of four Angelica species (Angelica sinensis (Oliv.) …”
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Correlating Microbial Dynamics with Key Metabolomic Profiles in Three Submerged Culture-Produced Vinegars by Juan J. Román-Camacho, Inés M. Santos-Dueñas, Isidoro García-García, Teresa García-Martínez, Rafael A. Peinado, Juan C. Mauricio

“…In this work, three acetification profiles in submerged culture using both synthetic and raw materials from Andalusia (Spain) were characterized by metagenomic (16S rRNA amplicon sequencing) and metabolomic tools (stir-bar sorptive extraction with thermo-desorption coupled to gas chromatography–mass spectrometry (SBSE-TD-GC−MS) and high-performance liquid chromatography (HPLC)). …”
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Quantifying LAGA mutated mouse IgG2a monoclonal antibody with a rapid pepsin digestion enabled immunoaffinity LC/MS/MS assay by Linlin Dong, Susan Chen, Konstantin Piatkov, Dong Wei, Mark G. Qian

“…Consequently, a new pepsin digestion-based liquid chromatography-tandem mass spectrometry (LC/MS/MS) method was successfully developed to support the mouse pharmacokinetic (PK) sample analysis. …”
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Seasonal investigation of ultrafine-particle organic composition in an eastern Amazonian rainforest by A. E. Thomas, H. S. Glicker, A. B. Guenther, R. Seco, O. Vega Bustillos, J. Tota, R. A. F. Souza, J. N. Smith

“…Samples collected during the three time periods were compiled and analyzed using liquid chromatography coupled with Orbitrap high-resolution mass spectrometry. Our findings suggest a sustained influence of isoprene organosulfate chemistry on ultrafine particles from the different periods. …”
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Enhancing the targeted and untargeted analysis of honey by vacuum-assisted SPME-GC × GC-MS. A green, practical, and highly informative approach by Damien Eggermont, Francesca Pardi, Giorgia Purcaro

“…In this work, we explored the use of Vac-HS coupled with comprehensive two-dimensional gas chromatography coupled with mass spectrometry to simultaneously determine 5-hydroxymethylfurfural (a semi-volatile processing marker in honey) and the entire volatile profile, which is recognized as a highly informative fingerprint of the geographical and botanical authenticity of honey. …”
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Evaluation of the Inhibitory Effect of Moringa oleifera Leaves Methanolic Extract against In Vitro Growth of Several Babesia Species and Theileria equi and the In Vivo Growth of Ba... by Mohamed Abdo Rizk, Shimaa Abd El-Salam El-Sayed, Mohamed Z. Sayed-Ahmed, Yosif Almoshari, Saad S. Alqahtani, Sarfaraz Ahmad, Nawazish Alam, Basma H. Marghani, Abdelbaset E. Abdelbaset, Ikuo Igarashi

“…Active principles of MOL extract were determined using liquid chromatography mass spectrometry (LC-MS). MOL’s anti-piroplasm efficacy was assessed both in vitro and in vivo using the SYBR Green I fluorescence assay. …”
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Deciphering of differences in gut microbiota and plasma metabolites profile between non-obese and obese Golden Retrievers dogs by Yazhen Cai, Huayu Tang, Guilin Xiang, Hongyu Yi, Jie Zhong, Zhaoxi Xie, Qinfeng Hu, Romaissaa El Bouhi, Pan Zhou, Yong Zhang, Honglin Yan

“…The fecal microbiome and plasma metabolome were determined using 16S rRNA amplicon sequencing and liquid chromatography-mass spectrometry, respectively.ResultsResults showed that the alanine aminotransferase activity and total bilirubin concentration, which have been measured using serum biochemistry analysis, were higher in the Obe group than in the Ctrl group (p &lt; 0.05). …”
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LRP11 facilitates lipid metabolism and malignancy in hepatocellular carcinoma by stabilizing RACK1 through USP5 regulation by Litao Liang, Wenbo Jia, Jinyi Wang, Yanzhi Feng, Deming Zhu, Wenhu Zhao, Chao Xu, Xiangyu Ling, Qingpeng Lv, Xiaoming Ai, Lianbao Kong, Wenzhou Ding

“…Nile red staining and lipid assays showed that LRP11 knockdown significantly reduces lipid accumulation in HCC cells, with a concurrent decrease in key lipid metabolism markers such as FSAN, ACLY and ACSL4, as demonstrated by Western blotting. Mass spectrometry (MS) and co-immunoprecipitation (Co-IP) revealed that LRP11 recruits USP5, enhancing USP5-mediated deubiquitination of RACK1. …”
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In vitro propagation of Codonopsis pilosula (Franch.) Nannf. using apical shoot segments and phytochemical assessments of the maternal and regenerated plants by Roggers, Gang, Richard, Komakech, Yuseong, Chung, Denis, Okello, Wook, Jin Kim, Byeong, Cheol Moon, Nam, Hui Yim, Youngmin, Kang

“…Furthermore, the tissues (roots and shoots) of maternal and in vitro‑regenerated C. pilosula plants were subjected to Fourier‑transform near‑infrared (FT‑NIR) spectrometry, Gas chromatography‑mass spectrometry (GC–MS), and their total flavonoids, phenolics, and antioxidant capacity were determined and compared. …”
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The antibacterial and antifungal potential of marine natural ingredients from the symbiont bacteria of mangrove by D. Pringgenies, W. Ari Setyati, F. Feliatra, D. Ariyanto

“…Further, everal tests were conducted, including the antibacterial test, antifungal test, molecular identification, and gas chromatography-mass spectrometry. The pathogenic bacteria used in the antibacterial test were Staphylococcus aureus, Vibrio harveyi, and Vibrio alginolyticusFINDINGS: The antibacterial test results showed that eight isolates were capable of producing an inhibition zone against S. aureus, seven isolates were positive for antibacterial activity against Vibrio harveyi, and 10 isolates were positive for antibacterial activity against Vibrio alginolyticus. …”
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Proteomic profiling of serum in cats with naturally occurring degenerative joint disease and co-morbid conditions by B. Duncan X. Lascelles, B. Duncan X. Lascelles, B. Duncan X. Lascelles, B. Duncan X. Lascelles, Rakesh Ponnala, Steven G. Kamerling, Tracey Williams

“…A greater understanding of the systems biology of DJD, DJD-associated pain, and CKD may contribute to identifying disease specific biomarkers and relevant targets for the development of therapeutics for the control of these conditions in cats, and help inform human pain therapeutic development.MethodsUsing mass spectrometry-based proteomic profiling of the serum of 200 highly phenotyped cats with varying burdens of DJD, pain, and CKD, we identified significant individual proteins and pathways.ResultsFunctional pathway analysis, based on differentially abundant proteins across individual disease states (DJD, pain, CKD), identified pathways playing a role in DJD and DJD-associated pain including acute phase response signaling, LXR/RXR and FXR/RXR activation and the complement system. …”
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Synthesis, Physicochemical Properties, and Ion Recognition Ability of Azulene-Based Bis-(Thio)Semicarbazone by Anamaria Hanganu, Catalin Maxim, Andreea Dogaru, Adrian E. Ion, Coralia Bleotu, Augustin M. Madalan, Daniela Bala, Simona Nica

“…Compounds <b>1</b> and <b>2</b> were identified by high-resolution mass spectrometry and characterized by IR, ¹H-NMR, ¹³C-NMR, and UV-vis spectroscopic techniques. …”
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Purification, Characterization and Antibacterial Mechanism of Plantaricin 2-1 by Mengyang LI, Xiaoxue CHE, Qingshen SUN

“…To explore the basic properties and antibacterial mechanism of bacteriocin produced by Lactobacillus plantarum L3, the strain was sub-cultured in MRS medium, and the broth was extracted by ethyl acetate extraction, followed by purification serially through dextran gel chromatography, cation exchange chromatography and reverse phase high performance liquid chromatography (RP-HPLC), and finally identified by liquid chromatography tandem mass spectrometry (LC-MS/MS). Listeria monocytogenes and Escherichia coli were used as indicator strain and the antibacterial mechanism of the plantaricin was determined by crystal violet staining, scanning electron microscopy, infrared spectroscopy, fluorescence spectroscopy, extracellular alkaline phosphatase (AKP), ATP, and lactate dehydrogenase (LDH) content analysis. …”
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