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Sources of polycyclic aromatic hydrocarbons exposure and their effects on glycolipid metabolism in pregnant women and their newborn in Haikou City, China
Published 2025-01-01“…Data on lifestyle and dietary habits were collected, and PAH levels in venous blood and umbilical cord blood were measured using gas chromatography-mass spectrometry. Glycolipid metabolism indicators, including fasting plasma glucose (FPG), triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL), were also measured. …”
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1202
PEBP1 amplifies mitochondrial dysfunction-induced integrated stress response
Published 2025-01-01“…The integrated stress response (ISR) serves as a critical adaptation mechanism to a variety of stresses, including those originating from mitochondria. By utilizing mass spectrometry-based cellular thermal shift assay (MS-CETSA), we uncovered that phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitory protein (RKIP), is thermally stabilized by stresses which induce mitochondrial ISR. …”
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1203
Discovery of novel serum peptide biomarkers for cholangiocarcinoma recurrence through MALDI-TOF MS and LC–MS/MS peptidome analysis
Published 2025-01-01“…This study aimed to identify novel peptide mass fingerprints (PMFs) and potential biomarker panels in the serum of CCA patients with early and late recurrence using mass spectrometry. Serum samples of 81 CCA patients were analyzed using MALDI-TOF MS and LC–MS/MS, with statistical analysis correlating peptide profiles with clinical outcomes like disease-free survival (DFS) and overall survival (OS). …”
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1204
Circadian Variation of Zinc, Copper, Selenium, and Bromine in Human Milk
Published 2025-01-01“…Milk samples were analysed using inductively coupled plasma mass spectrometry. Data on zinc, copper, selenium, and bromine concentrations were analysed using Microsoft Excel 2021 and reported descriptively to determine circadian variation. …”
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1205
Ciprofloxacin stress changes key enzymes and intracellular metabolites of Lactobacillus plantarum DNZ-4
Published 2022-03-01“…Gas chromatography-mass spectrometry was used to analysis the changes of main metabolites in the cells and principal component analysis and partial least square model were constructed. …”
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1206
Adulteration detection of plant protein beverages by UPLC-MS/MS based on signature peptide of allergen
Published 2024-11-01“…Hence, a novel method was developed for authentication by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Almond, peanut, walnut and soybean were hydrolyzed, followed by separation by NanoLC-Triple TOF MS. …”
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1207
Metabolomics-based study on the effect of low-voltage electrostatic field treatment on the storage quality of postharvest square bamboo shoots
Published 2025-01-01“…This study explored the effects of LP treatment on the storage quality of square bamboo shoots using physicochemical, gas chromatography–mass spectrometry, and metabolomics methods. Results showed that with prolonged storage, the LP-treated group had lower activities of peroxidase, phenylalanine ammonia-lyase, and lower levels of malondialdehyde, cellulose, and lignin compared to the control group, while superoxide dismutase and catalase activities and shear force values were higher. …”
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1208
Chemical Composition, Antioxidant Activity, and Antifungal Effects of Essential Oil from Laurus nobilis L. Flowers Growing in Morocco
Published 2020-01-01“…The chemical composition of the obtained essential oil and chemotypes was determined using gas chromatography coupled with mass spectrometry (GC/MS) and gas chromatography with flame ionization detection (GC-FID). …”
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1209
Comprehensive GC-MS Characterization and Histochemical Assessment of Various Parts of Three <i>Colchicum</i> Species from Bulgarian Flora
Published 2025-01-01“…Using gas chromatography-mass spectrometry (GC-MS), 66 metabolites were identified, encompassing free amino, organic, phenolic, and fatty acids, sugars, and alkaloids, which were distributed among various plant parts. …”
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1210
Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia.
Published 2022-01-01“…Induced expression of GFP-tagged wildtype and mutant MAB21L1 in human cells caused only modest transcriptional changes. Mass spectrometry of immunoprecipitated protein revealed that both mutant and wildtype MAB21L1 associate with transcription factors that are known regulators of PAX6 (MEIS1, MEIS2 and PBX1) and with poly(A) RNA binding proteins. …”
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1211
Microscopy and spatial-metabolomics identify tissue-specific metabolic pathways uncovering salinity and drought tolerance mechanisms in Avicennia marina and Phoenix dactylifera roo...
Published 2025-01-01“…Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) revealed tissue- and species-specific metabolite distributions in root tissues. …”
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1212
Metabolomic profiles of preterm small-for-gestational age infants
Published 2025-01-01“…Metabolomic analyses were performed using capillary electrophoresis time-of-flight mass spectrometry. The median GA at birth was not significantly different between the two groups [SGA, 32 (26–36) weeks; non-SGA, 32 (25–35) weeks; p = 0.661)]. …”
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1213
Effect of AAPH oxidation on digestion characteristics of seed watermelon (Citrullus lanatus var) kernels protein isolates
Published 2020-12-01“…The free sulfhydryl content of WMP was 18.24 mmol/g decreased to 11.25 mmol/g, α-helix decreased and β-sheet decreased in secondary structure, and its disulfide bond increased by 43.06 mmol/g from 39.57 mmol/g, enthalpy (ΔH) and denaturation temperature increased (Td) (P < 0.05). By mass spectrometry results of simulated gastric digestion products, it was found that oxidation adversely affected the digestion characteristics of WMP. …”
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1214
Phthalazine based hydrazone as potent radical scavenger: Synthesis, spectral characterization, single crystal X-ray diffraction, DFT studies, molecular docking, ADME, antioxidant a...
Published 2025-01-01“…FT-IR, 1H & 13C NMR, and Mass spectrometry were used to determine their structures, while Single crystal X-ray diffraction studies identified the hydrazone tautomer. …”
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1215
Palladium-catalyzed Suzuki–Miyaura cross-coupling with $\alpha $-aminophosphonates based on 1,3,4-oxadiazole as ligands
Published 2022-02-01“…The complex was fully characterized by elemental analysis, infrared, NMR and mass spectrometry. A solid-state structure revealed the trans coordination of the two nitrogenated ligands. …”
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1216
Effects of Soil Properties on Pb, Cd, and Cu Contents in Tobacco Leaves of Longyan, China, and Their Prediction Models
Published 2023-01-01“…Inductively coupled plasma-mass spectrometry was used to determine heavy metal in tobacco leaf. …”
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1217
Development of a sequential laser microdissection tissue cuts workflow for the spatial and quantitative analysis of drugs in fresh frozen tissue sections.
Published 2024-01-01“…Mass spectrometry imaging (MSI) is a well-established technique that allows to determine the distribution of small molecules, such as lipids, metabolites, and drugs, as well as large molecules in tissue sections. …”
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1218
The Inheritance and Variation of Floral Scent Compounds in Parent–Progeny Relationships of <i>Malus</i>
Published 2024-12-01“…In this study, the floral scent compounds and scent characteristics of five <i>Malus</i> taxa with clearly defined parent–progeny relationships were analyzed by sensory evaluation, an electronic nose, and gas chromatography–mass spectrometry. A total of 51 volatile compounds were identified in five taxa. …”
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1219
Preparation of Xanthine Oxidase Inhibitory Peptide from Black Bean Protein by Enzymatic Hydrolysis and Its Uric Acid-Lowering Activity in Vitro
Published 2024-12-01“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) identified 18 peptides in F3, with an average molecular mass of approximately 500–1 400 Da. …”
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1220
Screening of six medicinal plant species for antileishmanial activity
Published 2021-09-01“…After isolation and analysis of chemical components by ultra-high performance liquid chromatography-high-resolution tandem mass spectrometry (UHPLC-HRMS/MS), the extracts were also tested for toxicity in J774.A1 macrophages and human erythrocytes. …”
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