Comparative analysis of fruit quality parameters and volatile compounds in commercially grown citrus cultivars by Polat Yakup, Cimen Berken, Celik Ferit, Ekşi Esra, Koc Gokmen, Ercisli Sezai, Assouguem Amine, Aberkani Kamal, Iqbal Zafar, Mehta Chandra Mohan, Kafkas Nesibe Ebru

“…Volatile compound analysis was conducted using gas chromatography/mass spectrometry with solid-phase micro extraction (SPME) fibres (blue, red, and grey) for both fruit peel and juice. …”
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Proximate analysis and vitamin B contents of fresh-made, canned chickpea and broad bean dips commercially produced in Jordan. by Seham M Abu Jadayil, Ali K Alsaed, Iman F Mahmoud, Leena M Ahmad, Fatena Afaneh, Hanaa Khalaf, Mohammed Z Soudi

“…Furthermore, vitamins B were analyzed using liquid chromatography-mass spectrometry.<h4>Results</h4>Significant differences were detected between fresh-made and canned chickpea dips, with the former containing higher quantities of fiber (10.96g ± 0.32) while the latter containing higher quantities of proteins (8.06g ± 0.29), fats (8.05g ± 1.08), and the vitamins B1 (0.46 ± 0.02) and B5 (0.87 ± 0.02). …”
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Combined metabolomics and 16S rDNA sequence analyses of the gut microbiome reveal the action mechanism of Fructus Akebiae against hepatic fibrosis by Rong-Rong Wu, Duo-Rui Nie, Fang-Hui He, Zhi-Hang Li, Fei Xu, Fei Xu, Fei Xu

“…The gut microbiota was analyzed through 16S rDNA sequencing analysis of liver metabolites using liquid chromatography-mass spectrometry. Furthermore, network pharmacology was used to determine the specific molecular regulation mechanism of FAE in hepatic fibrosis treatment.ResultsFAE treatment markedly improved the pathological changes in the hepatic fibrosis. …”
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Bioactive Properties of <i>Pentacalia vaccinioides</i> (Kunth) Cuatrec. (Asteraceae) Essential Oils: Evaluation of Antimicrobial and Antioxidant Activities by Luis G. Sequeda-Castañeda, María A. Castellanos-Gómez, Carlos L. A. Céspedes-Acuña

“…The identification and quantification of the compounds present in the EOs were conducted by gas chromatography coupled to mass spectrometry (GC-MS). The main secondary metabolites identified in most samples obtained by different extraction techniques included phenol (~18%), 1S-α-pinene (~15%), β-phellandrene (~13%), β-pinene (~12%), 4-terpineol (~10%), γ-terpinene (~10%), trans-nerolidol (~8%), limonene (~8%), and β-thujene (~6%). …”
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Evaluation of volatile safety in children's play mats based on non-targeted screening and risk prioritization by Shuang Liang, Haoyang Shi, Yinhui Yang, Qing Zhang, Zhijuan Wang, Qing Lv

“…In this study, 34 play mats, comprising four materials (3 EPE, 15 XPE, 5 PVC, 11 EVA), were subjected to non-targeted screening based on headspace gas chromatography-Orbitrap high-resolution mass spectrometry (HS-GC-Orbitrap HRMS), which screened out 71 volatile substances. …”
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Lysine Reacts with Cholesterol Hydroperoxide to Form Secosterol Aldehydes and Lysine-Secosterol Aldehyde Adducts by George Wafula Wanjala, Arnold Nola Onyango, David Rasugu Abuga, John Kamathi Muchuna, Calvin Onyango, Moses Makayoto

“…Here, we subjected cholesterol to photosensitized oxidation, which predominantly produces Ch-5α-OOH and minor amounts of the 6α- and 6β-hydroperoxides, exposed the hydroperoxide mixture to lysine in the presence of the antioxidant 2,6-ditertiary-butyl-4-hydroxytoluene (BHT), and analysed the reaction mixture by liquid chromatography-electrospray ionization-mass spectrometry. Consistent with the postulated lysine-catalysed formation of secosterol aldehydes, we detected formation of the latter and several types of their lysine adducts, including carbinolamines, Schiff’s bases, and amide-type adducts. …”
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Prednisolone pharmacokinetics in dogs with protein‐losing enteropathy by Sara A. Jablonski, Jessica L. Strohmeyer, John P. Buchweitz, Andreas F. Lehner, Daniel K. Langlois

“…Total and non‐protein bound serum prednisolone concentrations were determined using liquid chromatography tandem‐mass spectrometry, and pharmacokinetics variables were derived from the drug concentration data. …”
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4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies by Ashanul Haque, Khalaf M. Alenezi, Mohd. Saeed Maulana Abdul Rasheed, Md. Ataur Rahman, Saleha Anwar, Shahzaib Ahamad, Dinesh Gupta

“…The drug-likeness feature and toxicity of the molecules were evaluated using QikProp and other tools.ResultsCompounds were synthesized following a multi-step approach and characterized using multi-nuclear magnetic resonance (1H/13C-NMR) and mass spectrometry. ATPase inhibition assay of the compounds against MARK4 showed an IC50 value in the micromolar (μM) range. …”
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Jararaca GPIb-binding protein causes thrombocytopenia during Bothrops jararaca envenomation by Marcelo Larami Santoro, Ana Teresa Azevedo Sachetto, Jaqueline Gomes Rosa, Ricardo José Soares Torquato, Débora Andrade-Silva, Dilza Trevisan-Silva, Cynthia Zaccanini de Albuquerque, Solange M. T. Serrano, Vânia Gomes de Moura Mattaraia, Aparecida Sadae Tanaka, Maria Elisa Peichoto

“…However, neither fraction D nor fraction E induced platelet aggregation in platelet-rich plasma or whole blood from humans or mice. By mass spectrometry analysis, fraction E was identified as jararaca glycoprotein Ib (GPIb)-binding protein. …”
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Universal, untargeted detection of bacteria in tissues using metabolomics workflows by Wei Chen, Min Qiu, Petra Paizs, Miriam Sadowski, Toma Ramonaite, Lieby Zborovsky, Raquel Mejias-Luque, Klaus-Peter Janßen, James Kinross, Robert D. Goldin, Monica Rebec, Manuel Liebeke, Zoltan Takats, James S. McKenzie, Nicole Strittmatter

“…Here, we describe a biomarker-based strategy that utilises bacterial small molecular metabolites and lipids for direct detection of bacteria in complex samples using mass spectrometry (MS). A spectral metabolic library of 233 bacterial species is mined for markers showing specificity at different phylogenetic levels. …”
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Recent Developments in Heavy Metals Detection: Modified Electrodes, Pretreatment Methods, Prediction Models and Algorithms by Yujie Shi, Shijie Zhang, Hang Zhou, Yue Dong, Gang Liu, Wenshuai Ye, Renjie He, Guo Zhao

“…This review aims to highlight the commonly used methods for detecting heavy metals (such as atomic absorption spectroscopy (AAS), atomic emission spectroscopy (AES), inductively coupled plasma–mass spectrometry (ICP-MS), square-wave anodic stripping voltammetry (SWASV), etc.), with a particular focus on electrochemical detection and electrode modification materials. …”
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Effect of tempering temperature on low-temperature impact toughness of 35MnB steel by Ping Ni, Wen Shi, Hengchang Lu, Bo Zhang, Han Dong

“…The form and distribution of boron in the steel were characterized by time-of-flight secondary ion mass spectrometry (TOF-SIMS) combined with transmission electron microscopy (TEM). …”
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Analysis of the Pyrolysis Kinetics, Reaction Mechanisms, and By-Products of Rice Husk and Rice Straw via TG-FTIR and Py-GC/MS by Li Lin, Yang E, Qiang Sun, Yixuan Chen, Wanning Dai, Zhengrong Bao, Weisheng Niu, Jun Meng

“…This study employed thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), and pyrolysis gas chromatography/mass spectrometry (Py-GC/MS) to characterize and provide insights into the pyrolysis behaviors and by-products of rice husk (RH) and rice straw (RS). …”
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Marine actinobacteria metabolites: unlocking new treatments for acne vulgaris by María Clara De La Hoz-Romo, María Clara De La Hoz-Romo, Luis Díaz, Luis Díaz, Javier Gómez-León, Marynes Quintero, Luisa Villamil

“…Chemical characterization was conducted using high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC–MS/MS). Among the extracts, six derived from Kocuria sp., Rhodococcus sp., Nocardia sp., Micrococcus sp., and Streptomyces sp. demonstrated significant antibacterial activity. …”
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Effects of pits of different ages on ethyl acetate and its metabolism-related microorganisms during strong-flavor Baijiu fermentation by Jing Zhang, Jing Zhang, Yunxuan Duan, Yang Lin, Jing Chen, Jie Cheng, Jie Cheng, Chuan Song, Jincen Zuo, Suyi Zhang, Suyi Zhang, Yong Zuo

“…In this study, the main esters and their related microorganisms in different years of pits (5, 35 and 100 years) of strong-flavor Baijiu were comprehensively researched by headspace solid-phase microextraction gas chromatography mass spectrometry (HS-SPME-GC-MS) and amplicon sequencing. …”
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Analysis and Evaluation of Quality Indicators and Volatile Compounds of Different Rice Cultivars with Geographical Indication by WANG Qin, ZHOU Changyan, ZHAO Xiaoyan, LI Xiaobei, LI Xujiao, JIANG Zhenghui, ZHANG Yanmei

“…Using headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS) followed by odor activity value (OAV) analysis, the major odor-active compounds of rice were identified as 2-acetyl-1-pyrroline, hexanal, heptanal, octanal, nonanal, trans-2-octenal, hexanol, 1-octen-3-ol, and heptanol. …”
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Aspilia africana (Pers.) C.D. Adams and Manihot esculenta Crantz Exhibit Antibacterial Activity against Resistant Salmonella typhi Strains by Richard Agyen, Yaw Duah Boakye, Theresa Appiah Agana, Vivian Etsiapa Boamah, Clement Osei Akoto, Michael Owusu, Francis Adu, Christian Agyare

“…Gas chromatography-mass spectrometry analysis of the extracts showed compounds such as n-hexadecanoic acid, 9,12,15-octadecatrienoic acid (9.55%), and 2H-benzo[F]oxireno[2,3-E]benzofuran-8(9H)-one in the A. …”
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Apolipoprotein C-I Levels Are Associated with the Urinary Protein/Urinary Creatinine Ratio in Pediatric Idiopathic Steroid-Sensitive Nephrotic Syndrome: A Case Control Study by Jun Odaka, Takahiro Kanai, Takane Ito, Takashi Saito, Jun Aoyagi, Hiroyuki Betsui, Takanori Yamagata

“…In the present study, we analyzed serum proteins using mass spectrometry (MS) to identify proteins associated with the pathophysiology of pediatric ISSNS. …”
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Simultaneous Determination of Three Active Forms of Vitamin B12 In Situ Produced During Fermentation by LC-MS/MS by Zhihao Fan, Yajie Li, Xia Fan, Pei Wang, Runqiang Yang, Chong Xie

“…Liquid chromatography–tandem mass spectrometry (LC-MS/MS) is advantageous for analyzing trace substances in food due to its high sensitivity. …”
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Systemic Proteomic Analysis Reveals Distinct Exosomal Protein Profiles in Rheumatoid Arthritis by Qiu Qin, Ronghua Song, Peng Du, Chaoqun Gao, Qiuming Yao, Jin-an Zhang

“…Totally, 12 specimens of plasma from 6 RA patients and 6 age- and gender-matched controls from the Chinese population were obtained for nanoscale liquid chromatography coupled to tandem mass spectrometry (nano-LC-MS/MS) analysis to identify exosomal profiles. …”
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