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1061
Synthesis and Anti-Inflammatory Activity of New Nicotinoyl Amides
Published 2024-10-01“…The structures of the new compounds were determined using NMR 1H and 13C spectroscopy methods, as well as data from two-dimensional spectra of COSY (1H-1H), HMQC (1H-13C), HMBC (1H-13C) and mass spectrometry. The results of an experimental study of the anti-inflammatory activity of synthesized new amides are presented. …”
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1062
In vitro and in silico insights into antimicrobial and anticancer activities of novel imidazo[2,1-b][1,3,4]thiadiazoles
Published 2024-12-01“…The derivatives were synthesized in two steps and thoroughly characterized using IR, 1H NMR, 13C NMR, and mass spectrometry. All the derivatives had shown fairly good antimicrobial activity against four microorganisms (Escherichia coli, Staphylococcus aureus, Mycobacterium smegmatis and Candida albicans) with minimum inhibition concentration’s ranging from 0.14 to 0.59 mM. …”
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1063
Effects of different Lys/Met ratios on the antioxidant capacity, tissue morphology, and fatty acid composition of subcutaneous fat in Tibetan sheep on low-protein diets: a lipidomi...
Published 2025-01-01“…Ultra-High Performance Liquid Chromatography–tandem Mass Spectrometry (UHPLC–MS/MS) was employed to explore the changes in various lipid subclasses in subcutaneous adipose tissue. …”
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1064
Evaluating the occurrence of trihalomethanes in drinking water and their implications for human health risk
Published 2024-12-01“…Using a gas-chromatography coupled mass-spectrometry (GC-MS) analysis method, water samples collected over the course of a year were analysed and revealed the cumulative sum of all trihalomethanes (ΣTHMs) saw a maximum concentration of 90.6 µg/L, with an average of 25.6 µg/L and a median of 22.2 µg/L with chloroform and bromoform being the most abundant. …”
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1065
Antioxidant and Antimicrobial Properties of the Essential Oil and Extracts of Zanthoxylum alatum Grown in North-Western Himalaya
Published 2013-01-01“…The essential oil obtained from the fresh leaves of Zanthoxylum alatum was analysed by gas chromatography/mass spectrometry (GC/MS). Fourteen components were identified, and linalool (30.58%), 2-decanone (20.85%), β-fenchol (9.43%), 2-tridecanone (8.86%), β-phellandrene (5.99%), Sabinene (4.82%), and α-pinene (4.11%) were the main components. …”
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1066
Evaluation of Bioactive Compounds and Chemical Elements in Herbs: Effectiveness of Choline Chloride-Based Deep Eutectic Solvents in Ultrasound-Assisted Extraction
Published 2025-01-01“…Additionally, macroelements (K, Na, Ca, Mg), micronutrients (Mn, Zn, Fe, Cu), and a toxic element (Cd) in four herbs were analyzed using inductively coupled plasma–mass spectrometry (ICP–MS). Determining the compositions of antioxidants and elements in herbs is essential for understanding their nutritive importance when applied in the food, cosmetic, and pharmaceutical industries.…”
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1067
Plant-Derived Compounds in Hemp Seeds (<i>Cannabis sativa</i> L.): Extraction, Identification and Bioactivity—A Review
Published 2024-12-01“…Identification methods such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) allowed for detailed chemical profiling of cannabinoids, terpenes, and phenolic substances. …”
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1068
Proteomic characterization of molecular mechanisms of paraquat-induced lung injury in a mouse model
Published 2025-01-01“…Lung tissue components were assessed with tandem mass spectrometry tag technology, and differentially expressed proteins (DEPs) were bioinformatically analyzed and investigated with parallel reaction monitoring. …”
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1069
Generation of Mature Nα-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α
Published 2013-01-01“…The Nα-acetylated Tα1 peptide was subsequently purified by reverse phase and cation exchange chromatography. Mass spectrometry indicated that the molecular mass of recombinant Nα-acetylated Tα1 was 3108.79 in, which is identical to the mass of Nα-acetylated Tα1 produced by total chemical synthesis. …”
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1070
Exploring grape juice volatile compounds after inactive yeast extract foliar treatment using SPME and GC–MS
Published 2025-01-01“…The volatile profile of the grape juice was determined using headspace solid phase microextraction (SPME) coupled with gas chromatography combined with mass spectrometry (GC–MS). At the end of this research, despite the application of yeast extract, no significant impact on vine productivity or the physicochemical parameters of the berries was observed. …”
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1071
A Possible Role of HMGB1 in DNA Demethylation in CD4+ T Cells from Patients with Systemic Lupus Erythematosus
Published 2013-01-01“…In this study, we identified proteins that bind to Gadd45a in CD4+ T cells during SLE flare by using the method of co-immunoprecipitation and mass spectrometry, High mobility group box protein 1 (HMGB1) is one of identified proteins. …”
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1072
The highly prolific phenotype of Lacaune sheep is associated with an ectopic expression of the B4GALNT2 gene within the ovary.
Published 2013-01-01“…The identification of these glycoproteins by mass spectrometry revealed at least 10 proteins, including inhibin alpha and betaA subunits, as potential targets of B4GALNT2 activity. …”
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1073
Separation, Purification, and Activity Analysis of Angiotensin Converting Enzyme Inhibitory Peptides in Enzymatically Hydrolyzed Egg Yolk of Chinese Soft-Shelled Turtle
Published 2025-01-01“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was utilized for the identification of the active peptides, and bioinformatics tools were utilized for activity evaluation. …”
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1074
Association between microplastics and the functionalities of human gut microbiome
Published 2025-01-01“…In the present study, concentrations of microplastics in human blood were detected through pyrolysis-gas chromatography/mass spectrometry in 39 adults. Five types of microplastics were found in human blood, including polyvinyl chloride, polyethylene, polypropylene, polystyrene, and polyamide 66. …”
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1075
Genome Structure of Bacillus cereus tsu1 and Genes Involved in Cellulose Degradation and Poly-3-Hydroxybutyrate Synthesis
Published 2017-01-01“…The five PHB genes in tsu1 (phaA, phaB, phaR, phaC, and phaP) were cloned and expressed with TOPO cloning, and the recombinant proteins were validated using peptide mapping of in-gel trypsin digestion followed by mass spectrometry analysis. The recombinant E. coli BL21 (DE3) (over)expressing phaC was found to accumulate PHB particles. …”
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1076
Volatile Organic Compounds of Anchote Tuber and Leaf Extracted Using Simultaneous Steam Distillation and Solvent Extraction
Published 2022-01-01“…Leaf and tuber powders were extracted for the first time to identify volatile organic compounds by simultaneous steam distillation and solvent extraction (SDE) and characterized using gas chromatography mass spectrometry (GC-MS). VOCs having an area percentage above 0.5% were used for identification analysis. …”
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1077
Cerebrovascular accidents association between serum trace elements and toxic metals level, a case-control study.
Published 2025-01-01“…The serum level of several metals, including Fe (Iron), Co (Cobalt), Ni (Nickel), Cu (copper), Zn (Zinc), Mn (Manganese), Pb (lead), Hg (Mercury), has been assessed using Inductively coupled plasma mass spectrometry (ICP-MS) method. Logistic regression (LR) has also been used to determine the association between metals' levels and CVA occurrence.…”
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1078
A framework for the simulation of individual glycan coordinates to analyze spatial relationships within the glycocalyx
Published 2025-01-01“…By integrating data from mass spectrometry and quantitative biological studies, these simulations aim to model possible experimental outcomes, which can then be used for further analysis, such as spatial point statistics. …”
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1079
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1080
Health Risk Assessment of Pesticide Residues in Drinking Water of Upper Jhelum Region in Kashmir Valley-India by GC-MS/MS
Published 2023-01-01“…Gas chromatography coupled with tandem mass spectrometry (GC-MS/MS) was used to determine pesticide residues in water samples. …”
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