Comprehensive analysis of ionomic profiling in Chlorella exposed to chlorpyrifos by Qing-Qing Yu, Yulong Zhang, Shiyuan Zhao, Min Pang, Pei Jiang, Pei Qu

“…However, little is known about the toxicological mechanism of CPF on marine microalgae, which is the main primary producer in the marine ecosystem.MethodsThis study explored the ion changes of microalgae Chlorella vulgaris under the stress of CPF through Inductively Coupled Plasma Mass Spectrometry (ICP-MS).ResultsSignificant disparities in ionomics among control and treatment group were observed through pattern recognition analysis (principal component analysis, PCA; orthogonal partial least squares discriminant analysis, OPLS-DA), indicating that CPF may impede their growth by disrupting the homeostasis of crucial elements within algal cells.DiscussionThis study elucidated the inhibitory impact of CPF on green algae growth and its potential mechanism of toxicity through ICP-MS, providing crucial insights for a comprehensive understanding of the influence of organophosphorus pesticides on aquatic ecosystems.…”
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Cell Labeling with 15-YNE Is Useful for Tracking Protein Palmitoylation and Metabolic Lipid Flux in the Same Sample by Nadine Merz, Karin Schilling, Dominique Thomas, Lisa Hahnefeld, Sabine Grösch

“…In this study, we developed a method to track 15-YNE incorporation into lipids using liquid chromatography high-resolution mass spectrometry (LC-HRMS) as well as protein palmitoylation in the same sample. …”
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Effect of H2O2 induced oxidative stress on volatile organic compounds in differentiated 3T3-L1 cells by Adebowale Samuel Oyerinde, Vaithinathan Selvaraju, Melissa Boersma, Jeganathan Ramesh Babu, Thangiah Geetha

“…The effect of OS on cell metabolism was analyzed by detecting VOCs in the headspace of the cells using solid phase micro extraction (SPME) and gas chromatography-mass spectrometry (GCMS). Our findings indicate that H2O2 concentrations exceeding 300 µM induce significant OS, leading to adipocyte apoptosis, as evidenced by various assays. …”
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Multifaceted roles of melatonin: Investigating coffee leaf melatonin concentration as a potential indicator of vegetative growth by Siswanto Dian, Nanda Aldian Dwi, Muwahida Imroatin, Istiqomah Nurul, Munawarti Aminatun, Mastuti Retno

“…Our research posits that melatonin concentrations vary with leaf age and can be effectively detected through Thin Layer Chromatography (TLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis. Results showed that all leaf samples—young, middle-aged, and old—from both species exhibited melatonin, confirming its role in various physiological processes. …”
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Proteomic Analysis of Saliva Identifies Potential Biomarkers for Orthodontic Tooth Movement by Mohd Faiz Ellias, Shahrul Hisham Zainal Ariffin, Saiful Anuar Karsani, Mariati Abdul Rahman, Shahidan Senafi, Rohaya Megat Abdul Wahab

“…Differentially expressed protein spots were then identified by MALDI-TOF/TOF tandem mass spectrometry. Nine proteins were found to be differentially expressed; however, only eight were identified by MALDI-TOF/TOF. …”
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Assessing the Proteomic Activity of the Venom of the Ant Ectatomma tuberculatum (Hymenoptera: Formicidae: Ectatomminae) by Juliana Rocha da Silva, Aline Zanotelli de Souza, Carlos Priminho Pirovani, Helena Costa, Aline Silva, João Carlos Teixeira Dias, Jacques Hubert Charles Delabie, Renato Fontana

“…In this study, we have identified proteins from the venom of Ectatomma tuberculatum by means of 2D PAGE, followed by tandem nanochromatography with mass spectrometry. A total of 48 proteins were identified, of which 42 are involved in metabolic processes, transport, and structural support. …”
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Identification and characterization of a novel tetrapeptide from enzymatic hydrolysates of Baijiu byproduct by Qiang Wu, Changqing Zhong, Guirong Zeng, Xu Zhang, Liping Xiang, Chang Wan, Yougui Yu

“…A superior ACE inhibitory peptide was separated and purified by ultrafiltration and high-performance liquid chromatography (HPLC), and its amino acid sequence was further identified as Gln-Gly-Val-Pro (QGVP) by electrospray mass spectrometry (ESI-MS). QGVP formed 6 hydrogen bonds with the active site of ACE, which is responsible for reducing α-helix structure content of ACE causing subsequent inactivation. …”
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The First Infant Bloodstream Infection Caused by Pantoea dispersa in China: A Case Report and Literature Review by Yu W, Sun Z, Wang M, Li Z, Zhang C, Sun Y, Wang S

“…With the advancement in mass spectrometry and gene sequencing technologies, human infections caused by Pantoea have increasingly been recognized, raising concerns regarding its pathogenicity and nosocomial transmission that clinicians must address. …”
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Identification of Volatile Compounds and Insecticidal Activity of Essential Oils from Origanum compactum Benth. and Rosmarinus officinalis L. against Callosobruchus maculatus (Fab.... by Asmae Baghouz, Yamna Bouchelta, Imane Es-safi, Mohammed Bourhia, El Moussaoui Abdelfattah, Abdullah A. Alarfaj, Abdurahman Hajinur Hirad, Hiba-Allah Nafidi, Raja Guemmouh

“…(EOR) were extracted by use of hydrodistillation, and their volatile compounds were profiled by gas chromatography-mass spectrometry (GC-MS). The insecticidal activity of extracted EOC and EOR was evaluated against C. maculatus. …”
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Investigation of CO2 Extract of Portulaca oleracea for Antioxidant Activity from Raw Material Cultivated in Kazakhstan by Meruyert I. Tleubayeva, Raisa M. Abdullabekova, Ubaidilla М. Datkhayev, Margarita Yu. Ishmuratova, Mereke B. Alimzhanova, Kaldanay K. Kozhanova, Aida M. Seitaliyeva, Kairat S. Zhakipbekov, Zhanar B. Iskakova, Elmira A. Serikbayeva, Elena V. Flisyuk

“…Gas chromatography-mass spectrometry (GC-MS) chemical analysis of Portulaca oleracea CO2 extract dissolved in hexane revealed 37 components, including a complex mixture of aldehydes, alkanes, alkenes, esters, diterpenes, steroids, vitamin E, and carbohydrates. …”
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Synthesis, Spectroscopic Characterization, and Biological Evaluation Studies of 5-Bromo-3-(((hydroxy-2-methylquinolin-7-yl)methylene)hydrazono)indolin-2-one and Its Metal (II) Comp... by Kuruba Siddappa, Nabiya Sultana Mayana

“…The Schiff base ligand 5-bromo-3-(((8-hydroxy-2-methylquinolin-7-yl)methylene)hydrazono)indolin-2-one (BHMQMHI) was prepared via condensation of 5-bromo-3-hydrazonoindolin-2-one and 7-formyl-8-hydroxy-2-methylquinoline and its Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II) complexes have been synthesized and characterized by elemental analysis, conductance data, magnetic susceptibility measurements, IR, UV-Vis, mass spectrometry, 1H NMR, ESR, XRD, and thermal studies. …”
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Copepod Lipidomics: Fatty Acid Substituents of Structural Lipids in <i>Labidocerca aestiva</i>, a Dominant Species in the Food Chain of the Apalachicola Estuary of the Gulf of Mexi... by Paul L. Wood, Stan C. Kunigelis

“…We utilized high-resolution tandem mass spectrometry (≤2 ppm mass error) to characterize the fatty acid substituents of triacylglycerols, glycerophosphocholines, ceramides, and sphingomyelins of <i>Labidocerca aestiva</i>. …”
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Stability Study of Algerian Nigella sativa Seeds Stored under Different Conditions by Muhammad Safwan Ahamad Bustamam, Kamarul Arifin Hadithon, Ahmed Mediani, Faridah Abas, Yaya Rukayadi, Nordin Lajis, Khozirah Shaari, Intan Safinar Ismail

“…Six replicates each were prepared and analyzed with Headspace-Gas Chromatography-Mass Spectrometry (HS-GC-MS) for three time points at the initial (1st day (0)), 14th (1), and 28th (2) day of storage. …”
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On the Use of Potential Denaturing Agents for Ethanol in Direct Ethanol Fuel Cells by Domnik Bayer, Florina Jung, Birgit Kintzel, Martin Joos, Carsten Cremers, Dierk Martin, Jörg Bernard, Jens Tübke

“…Beside, basic electrochemical tests, differential electrochemical mass spectrometry (DEMS) and fuel cell tests were conducted. …”
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Diagnostic and predictive values of serum metabolic profiles in sudden sensorineural hearing loss patients by Xiangsheng Wang, Yan Gao, Ruirui Jiang

“…Serum metabolites were detected by liquid chromatography-mass spectrometry, and metabolic profiles were analyzed. …”
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Quality analysis of Idesia polycarpa fruit oil samples from cultivars with different phenotypes by Tianting Luo, Jiaqi Xu, Zhouqin Zhen, Xue Pan, Lang Feng, Likang Qin, Tingyuan Ren

“…A total of 532 aroma compounds were identified via gas chromatography–mass spectrometry (GC–MS), with terpenes as the major contributors. …”
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Simultaneous Determination of Five Chromones of Radix Saposhnikoviae Extract in Rat Plasma by UPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Febrile R... by Li Meng, Hui Gao, Bin Chen, Peng-peng Liu, Guo-shun Shan, Fan Zhang, Tian-zhu Jia

“…A rapid and sensitive quantitative analytical method was established for the simultaneous determination of five chromones (prim-O-glucosylcimifugin, cimifugin, 4′-O-β-D-glucosyl-5-O-methylvisamminol, 5-O-methylvisammiol, and sec-o-glucosylhamaudol) in the plasma of RS-treated rats for the first time using ultra performance liquid chromatography- (UPLC-) tandem mass spectrometry. The Waters Acquity UPLC BEH C18 (50 mm × 2.1 mm, 1.7 μm) was used as the chromatographic column, 0.1% formic acid water and 0.1% formic acid acetonitrile comprised the mobile phases, and all samples were determined under positive ion mode. …”
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Antioxidant Activity In Vitro Guided Screening and Identification of Flavonoids Antioxidants in the Extract from Tetrastigma hemsleyanum Diels et Gilg by Li Ding, Xiaomin Zhang, Jiajia Zhang

“…The molecular weight of the above antioxidant components was investigated using the qualitative analytical method of high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (HPLC-Q-TOF LC/MS). Based on the concentrations of the samples (0.2–4 mg/mL), the DPPH free radical scavenging ability, ABTS+ free radical scavenging ability, hydroxyl free radical scavenging ability, and Fe3+ reducing ability of the ethyl acetate extract (EAE) were stronger than that of the crude extract (CE), petroleum ether extract (PEE), and n-butanol extract (BE). …”
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3-Methyl-4-Nitrobenzoate Derivates as Antifungal Drug Candidates: Biological and In Silico Evaluation by Alana R. Ferreira, Yunierkis P. Castillo, Ana C. M. Andrade, Diego F. Nóbrega, João Paulo G. de Oliveira, Tamires C. Lima, Ricardo D. de Castro, Damião P. de Sousa

“…The chemical structure of the obtained products was confirmed using Infrared, 1H and APT-13C nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. The antifungal assay results showed that the screened compounds exhibited different levels of activity depending on the structural variation and tested strain. …”
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Cu(II) and Ni(II) Complexes with New Tridentate NNS Thiosemicarbazones: Synthesis, Characterisation, DNA Interaction, and Antibacterial Activity by Dorian Polo-Cerón

“…The ligands and their metal complexes were characterised by different physicochemical techniques, including elemental and thermogravimetric analysis; UV-Vis, IR, 1H-NMR, and 13C-NMR spectroscopy; molar conductance measurements; and mass spectrometry. The crystal structure of the H2L1 ligand was determined by single crystal X-ray diffraction studies. …”
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