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641
The Drug Excipient Cyclodextrin Interacts With -Luciferin and Interferes With Bioluminescence Imaging
Published 2016-01-01“…Flow cytometry revealed that HPCD resulted in reduced cellular accumulation of d -luciferin, and mass spectrometry revealed d -luciferin HPCD species, confirming a direct interaction. …”
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642
Absorption and Metabolism Characteristics of Rutin in Caco-2 Cells
Published 2013-01-01“…The intestinal absorption and metabolism characteristics of the potentially beneficial polyphenol rutin were studied by measuring the intracellular accumulation and transport of rutin into Caco-2 cells with the sensitive and reliable analytical method of HPLC-coupled tandem mass spectrometry. Rutin and glucuronidated rutin were absorbed differently by the basolateral and apical membranes, and rutin showed differential permeability through the apical and basolateral sides. …”
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643
Untargeted metabolomics of Aloe volatiles: Implications in pathway enrichments for improved bioactivities
Published 2025-02-01“…The leaves of five highly utilized Aloe sp. were subjected to untargeted gas chromatography-mass spectrometry analysis followed by testing of free-radical scavenging effects against components of the Fenton and Haber-Weiss reaction. …”
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644
Spectrum-Effect Relationships of Flavonoids in Glycyrrhiza uralensis Fisch.
Published 2020-01-01“…After HPLC-quadrupole time-of-flight mass spectrometry and standard comparison, these five identified compounds (liquiritin apioside, neoisoliquiritin, licochalcone A, licochalcone B, and licochalcone C) could be used to evaluate licorice quality with regard to its efficacy. …”
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645
Simultaneous HPLC Determination of Chlordiazepoxide and Mebeverine HCl in the Presence of Their Degradation Products and Impurities
Published 2015-01-01“…The chemical structure of MBV degradation product was ascertained by mass spectrometry and IR studies.…”
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646
Validation of Simultaneous Quantitative Method of HIV Protease Inhibitors Atazanavir, Darunavir and Ritonavir in Human Plasma by UPLC-MS/MS
Published 2014-01-01“…The paper describes a selective, sensitive, and robust method for simultaneous determination of three protease inhibitors atazanavir, darunavir and ritonavir in human plasma by ultra performance liquid chromatography-tandem mass spectrometry. Materials and Methods. The sample pretreatment consisted of solid phase extraction of analytes and their deuterated analogs as internal standards from 50 μL human plasma. …”
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647
Pheromone Production, Attraction, and Interspecific Inhibition among Four Species of Ips Bark Beetles in the Southeastern USA
Published 2012-01-01“…Hindgut volatiles from attacking, unmated males of Ips avulsus, I. calligraphus, I. grandicollis, and I. pini were analyzed by combined gas chromatography and mass spectrometry. Based on the quantitative identifications of hindguts and subsequent individual aerations, baits were formulated and a combined species-specific subtractive field bioassay was set up for the four bark beetle species. …”
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648
Application of Metabolomics in Thyroid Cancer Research
Published 2015-01-01“…Metabolomics using mass spectrometry and magnetic resonance spectroscopy techniques allows qualitative and quantitative profiling of small molecules present in biological systems. …”
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649
Upper Gastrointestinal Bleeding from Gastric Amyloidosis in a Patient with Smoldering Multiple Myeloma
Published 2015-01-01“…Liquid chromatography tandem mass spectrometry performed on peptides extracted from Congo red-positive microdissected areas of paraffin-embedded stomach specimens revealed a peptide profile consistent with AL- (lambda-) type amyloidosis. …”
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650
Physiological consequences of Aldolase C deficiency during lactation.
Published 2024-01-01“…Biochemical analysis of milk identified that milk from Aldoc-/- dams have significantly higher galactose, lower lactose, and cholesterol content. Mass spectrometry analysis of milk lipids from Aldoc-/- dams revealed significantly lower quantities of medium and long chain fatty acid containing triglycerides, which has direct implications on lactation as these are the predominant triglycerides synthesized from glucose in human mammary gland. …”
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651
Migration of Two Synthetic Phenolic Antioxidants and Their Degradation Products from Wheat Straw-Based Plastic Lunch Boxes
Published 2024-12-01“…A method based on gas chromatography-mass spectrometry (GC-MS) was developed for the determination of the residues of 2,4-di-tert-butylphenol (2,4-DTBP), butylated hydroxytoluene (BHT) and its derivatives 2,6-di-tert-butyl-p-benzoquinone (BHT-Q) and 3,5-di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) and their migration to isooctane from wheat straw-based plastic lunchboxes. …”
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652
Characterization and Synergistic Antimicrobial Evaluation of Lipopeptides from Bacillus amyloliquefaciens Isolated from Oil-Contaminated Soil
Published 2019-01-01“…These mass ion peaks attributed to surfactin homologs. By tandem mass spectrometry, five variants of surfactin with the same amino acid sequence in peptide moiety could be revealed. …”
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653
UPLC-TOF-MS Characterization and Identification of Bioactive Iridoids in Cornus mas Fruit
Published 2013-01-01“…An ultra performance liquid chromatography (UPLC) coupled with photodiode array spectrophotometry (PDA) and electrospray time-of-flight mass spectrometry (ESI-TOF-MS) was employed and mass parameters were optimized. …”
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654
Nematicidal Constituents from the Essential Oil of Chenopodium Ambrosioides Aerial Parts
Published 2011-01-01“…The essential oil of C. ambrosioides was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 27 components of the essential oil were identified. …”
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655
The Addition of Tomato and Spinach Powder to Semolina Pasta: A Study of the Impact of the Production Process and Cooking on Phenolic Compounds
Published 2025-01-01“…High-performance liquid chromatography–electrospray ionization triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS) was employed to analyse the free and bound phenolic content in the raw materials, as well as in both dried uncooked and cooked pasta. …”
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656
Sweat Cortisol and Cortisone Determination in Healthy Adults: UHPLC-MS/MS Assay Validation and Clinical Application
Published 2022-01-01“…A simple and effective ultra-high-performance liquid chromatography assay linked to tandem mass spectrometry (UHPLC-MS/MS) for measuring cortisol and cortisone levels in human sweat has been developed and validated. …”
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657
Analysis of Distribution Characteristics and Variation Trends of Organic Matters in Panjiakou Reservoir
Published 2020-01-01“…In order to understand the improvement of water environment by cage-cleanup-activities in Panjiakou Reservoir,and to find out the types and characteristics of main pollutants in Panjiakou Reservoir,this paper carries out analysis and research on surface water samples in different time and space in the study area.The water samples of Panjiakou Reservoir in 2017 and 2018 are tested by the high-throughput screening technology of full two-dimensional gas chromatography time-of-flight mass spectrometry.The results are further confirmed by the matching degrees,detection rates and other conditions.The confirmed results are classified according to the chemical properties and purposes,and the final results are used to analyze the trend of pollutant species change.Compared with the test results in 2017,there were 244 compounds reduced in 2018,including 38 ketones,27 alkanes,26 phenols,21 ethers,15 organic acids,etc.Among them,25 for industrial intermediates,14 for flavors and fragrances,12 for food additives,8 for industrial use,6 for pharmaceutical products,14 for plasticizers,and so on.Compared with the results in 2017,there were 22 compounds increased in 2018,including 10 esters,3 ketones,2 ethers,1 benzene,1 alcohol, 1 aldehyde,1 organic acid,etc.…”
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658
Untargeted Metabolomics Analysis Reveals the Effect of Fixation on the Profile of Volatile Compounds of Cyclocarya paliurus Tea
Published 2024-08-01“…The aim of this study was to determine the volatile metabolites in fixated and unfixated C. paliuru s tea by gas chromatography-mass spectrometry in order to identify the volatile compounds that differentiate them and establish the key aroma compounds. …”
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659
Characterization of Jamaican Delonix regia and Cassia fistula Seed Extracts
Published 2016-01-01“…Lipid extracts were characterized by nuclear magnetic resonance spectroscopy and gas chromatography/mass spectrometry. Zinc concentration was determined by atomic absorption spectroscopy. …”
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660
Arabidopsis conditional photosynthesis mutants abc1k1 and var2 accumulate partially processed thylakoid preproteins and are defective in chloroplast biogenesis
Published 2025-01-01“…We employ a combination of Western blotting and mass spectrometry to analyze proteins in var2 and abc1k1. …”
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