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Pan-tumor analysis to investigate the obesity paradox in immune checkpoint blockade
Published 2025-01-01Get full text
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Navigating Ethical Dilemmas Of Generative AI In Medical Writing
Published 2024-10-01“… The history of humankind is marked by revolutionary inventions that completely transformed the quality and trajectory of human lives. …”
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Effect of Benzothiazoline Ligand and Corresponding Organoantimony(V) Derivative on the Reproductive System of Male Rats
Published 2006-01-01“…The production of preleptotene spermatocytes was decreased by <mml:math> <mml:mtext>36</mml:mtext><mml:mtext>.57%</mml:mtext> </mml:math>; <mml:math> <mml:mtext>57</mml:mtext><mml:mtext>.23%</mml:mtext> </mml:math>, pachytene spermatocytes by <mml:math> <mml:mtext>40</mml:mtext><mml:mtext>.06%</mml:mtext> </mml:math>; <mml:math> <mml:mtext>62</mml:mtext><mml:mtext>.01%</mml:mtext> </mml:math>, and secondary spermatocytes by <mml:math> <mml:mtext>52</mml:mtext><mml:mtext>.45%</mml:mtext> </mml:math>; <mml:math> <mml:mtext>63</mml:mtext><mml:mtext>.22%</mml:mtext> </mml:math>, following the treatment of compounds <mml:math> <mml:mtext mathvariant="bold">1</mml:mtext> </mml:math> and <mml:math> <mml:mtext mathvariant="bold">2</mml:mtext> </mml:math>, respectively. The marked reduction in sperm motility and density resulted in infertility by <mml:math> <mml:mtext>100%</mml:mtext> </mml:math>. …”
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The bile acid chenodeoxycholic acid associates with reduced stroke in humans and mice
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Gonadal Histology and Expression Analysis of Sex Characteristic Genes in Grass Carp at Different Ages
Published 2025-02-01“…At 2 months of age, primitive germ cells were first observed in the reproductive crest, marking the formation of their primitive gonads. At 3-month- old, ovarian cavities and lobules were observed in the gonads of female grass carp. …”
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Robustness and limitations of maximum entropy in plant community assembly
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Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials
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Le sanctuaire romain du Vigneau à Pussigny (Indre-et-Loire) : un lieu de mémoire, de vie et d’accueil
Published 2023-12-01“…The upper portion of the slope is marked by funerary occupations, with a first necropolis dated to the Middle Neolithic. …”
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Une cave à amphores, une statue en pierre et une tête coupée de la fin de l’âge du Fer à Châteaumeillant (Cher)
Published 2021-12-01“…The loss of the canines and incisors is further indication of the possibility that the skull was exposed, possibly showcased in an elevated manner. The Gauls’ marked interest in heads is known from ancient times, and the practice of removing skulls and subjecting them to a particular treatment, separate from the rest of the skeleton is attested to in Gaul from the 5th to the 1st c. …”
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The American Society of Pain and Neuroscience (ASPN) Guidelines and Consensus on the Definition, Current Evidence, Clinical Use and Future Applications for Physiologic Closed-Loop...
Published 2025-02-01“…Jason E Pope,1 Timothy Ray Deer,2 Dawood Sayed,3 Ajay B Antony,4 Harjot Singh Bhandal,1 Aaron K Calodney,5 Krishnan Chakravarthy,6 Shrif Costandi,7 Jack Diep,8 Shravani Durbhakula,9 Michael A Fishman,10 Christopher Gilligan,11 Johnathan Heck Goree,12 Maged Guirguis,13 Jonathan Michael Hagedorn,14 Corey William Hunter,15,16 Jan Willem Kallewaard,17,18 Leonardo Kapural,19– 21 Christopher M Lam,3 Sean Li,22 Brian Mayrsohn,23,24 Harold Nijhuis,25 Serge Nikolic,26 Erika A Petersen,27 Lawrence Raymond Poree,28 Shawn K Puri,29 David E Reece,30 Steven Mark Rosen,31 Marc A Russo,32 Jay M Shah,33 Peter Sean Staats,34 Paul Verrills,35 Chau M Vu,1 Robert M Levy,36 Nagy Mekhail37 1Evolve Restorative Center, Santa Rosa, CA, USA; 2Pain Services, The Spine & Nerve Center of the Virginias, Charleston, WV, USA; 3Department of Anesthesiology and Pain Medicine, The University of Kansas Medical Center, Kansas City, KS, USA; 4The Orthopaedic Institute, Gainesville, FL, USA; 5Clinical Research, Precision Spine Care, Tyler, TX, USA; 6Anesthesiology and Pain Medicine, Solaris Research Institute, Wilmington, DE, USA; 7Pain Medicine, Cleveland Clinic, Cleveland, OH, USA; 8Nevada Pain Management, Las Vegas, NV, USA; 9Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA; 10Michael Fishman MD PLLC, Lebanon, PA, USA; 11Robert Wood Johnson University Hospital, New Brunswick, NJ, USA; 12Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 13Interventional Pain Management Department, Ochsner Health System, New Orleans, LA, USA; 14Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA; 15Ainsworth Institute of Pain Management, New York City, NY, USA; 16Physical Medicine & Rehabilitation, Icahn School of Medicine at Mount Sinai Hospital, New York City, NY, USA; 17Amsterdam University Medical Centre, Amsterdam, The Netherlands; 18Rijnstate Hospital, Arnhem, The Netherlands; 19Carolinas Pain Institute, Winston Salem, NC, USA; 20Centers for Clinical Research, Winston Salem, NC, USA; 21Chronic Pain Research Institute, Winston Salem, NC, USA; 22National Spine and Pain Centers, Shrewsbury, NJ, USA; 23Interventional Pain Management, Maywell Health, Plainview, NY, USA; 24Interventional Pain Management, Maywell Health, New York City, NY, USA; 25Anesthesiology, St Antonius Hospital, Nieuwegein, Utrecht, The Netherlands; 26Pain Medicine and Neuromodulation, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK; 27Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 28Anesthesia- Division of Pain Medicine, University of California, San Francisco, CA, USA; 29Integrated Pain Associates, Killeen, TX, USA; 30Absolute Pain Management, Rockville, MD, USA; 31Delaware Valley Pain and Spine Institute, Trevose, PA, USA; 32School of Biomedical Sciences, University of Newcastle, Newcastle, NSW, Australia; 33Samwell Institute of Pain Management, Colonia, Livingston, and Englewood, NJ, USA; 34National Spine and Pain Centers, Atlantic Beach, FL, USA; 35Metropain, Melbourne, VIC, Australia; 36Neuromodulation: Technology at the Neural Interface, International Neuromodulation Society, Boca Raton, FL, USA; 37Evidence-Based Pain Management Research, Cleveland Clinic, Cleveland, OH, USACorrespondence: Timothy Ray Deer, The Spine and Nerve Center of the Virginias, 400 Court Street, Charleston, WV, 25304, USA, Tel +1 304 347 6141, Email doctdeer@aol.comIntroduction: Neuromodulation has been a staple of treatment for moderate-to-severe chronic refractory pain since the introduction of the first spinal cord stimulator by Norman Shealy in 1967. …”
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