Traditional Chinese medicine manual therapy for adolescent idiopathic scoliosis: a case report by Bowen Zhu, Miaoxiu Li, Jun Ren, Tianxiang He, Xin Zhou, Shoujian Wang, Lingjun Kong, Min Fang, Min Fang

“…ObjectivesThis case demonstrates the efficacy and safety of Traditional Chinese Medicine manual therapy (TCMMT) for the treatment of mild to moderate AIS.MethodsAn 10-year-old girl who suffered from low back pain (LBP) with marked shoulder inequality and razorback postural abnormalities, with a clinical diagnosis of idiopathic scoliosis, and the Cobb angle of 20° and angle of trunk rotation (ATR) of the thoracic vertebral segment at 7°, and ATR of the lumbar vertebral segment at 8°, was treated with TCMMT. …”
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Ultrasound stimulated perfluorobutane microbubbles cavitation enhanced the therapeutic effect of colchicine in rats with acute gouty arthritis by Ji-cheng Zhang, Bo Gou, Tian-rui Wang, Wan-tai Dang, Yan-hui Li, Wen Wen, Jian Liu

“…Results: When compared with groups A, B, and D, the AUC was markedly higher in groups C, E, and F (all P < 0.05). …”
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Evaluating quality of life improvements in endometriosis patients following laparoscopic surgery using EHP-30 scale by Yuyan Guo, Penghui Huang, Chaobin Liu, Zhenna Wang, Yi Wang, Wei Qi, Xi Xie, Zhenhong Wang, Jinna Zhang, Shunhe Lin

“…Laparoscopic surgery resulted in a significant reduction in EHP-30 subscale scores (P ≤ 0.002), indicating a marked improvement in HRQoL among endometriosis patients. …”
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Low light reduces saffron corm yield by inhibiting starch synthesis by Weijing Yang, Weijing Yang, Xin Li, Xin Li, Fei Chang, Fei Chang, Xue Qiu, Xulong Huang, Xulong Huang, Zhan Feng, Zhan Feng, Jie Yan, Jie Yan, Qinghua Wu, Qinghua Wu, Feiyan Wen, Feiyan Wen, Jin Pei, Jin Pei, Tao Zhou, Tao Zhou

“…Saffron plants under LL had larger, longer leaves with a higher proportion of dry weight (DW) compared to those under NL. Despite the marked inhibition of photosynthetic capacity, initial DW, sucrose and glucose concentrations in leaves were comparable to those under NL. …”
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Astaxanthin mitigates doxorubicin-induced cardiotoxicity via inhibiting ferroptosis and autophagy: a study based on bioinformatic analysis and in vivo/vitro experiments by Bowen Yin, Jingyi Ren, Xuanyi Liu, Yadong Zhang, Jinshi Zuo, Rui Wen, Huanting Pei, Miaomiao Lu, Siqi Zhu, Zhenao Zhang, Ziyi Wang, Yanyi Zhai, Yuxia Ma

“…Mechanistically, ASX markedly ameliorates levels of ferroptosis and autophagy both in vitro and in vivo. …”
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Association between PNPLA2 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in a Chinese Han Population with Type 2 Diabetes by Hailing Zhao, Haojun Zhang, Yan Wang, Tingting Zhao, Meihua Yan, Xi Dong, Qian Wang, Jialin Li, Liang Ma, Ping Li

“…The combined effect of PNPLA2 rs28633403 AA+rs1138714 AG or GG genotype showed an association with DKD, adjusted by confounders (aOR, 2.194; 95% CI 1.378-3.492; P=0.001), which was considered statistically significant with a markedly increased risk of DKD after a Holm-Bonferroni correction for multiple tests (P<0.00125). …”
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Exosomal mir-126-3p derived from endothelial cells induces ion channel dysfunction by targeting RGS3 signaling in cardiomyocytes: a novel mechanism in Takotsubo cardiomyopathy by Xuehui Fan, Guoqiang Yang, Yinuo Wang, Haojie Shi, Katja Nitschke, Katherine Sattler, Mohammad Abumayyaleh, Lukas Cyganek, Philipp Nuhn, Thomas Worst, Bin Liao, Gergana Dobreva, Daniel Duerschmied, Xiaobo Zhou, Ibrahim El-Battrawy, Ibrahim Akin

“…Abstract Background Takotsubo cardiomyopathy (TTC) is marked by an acute, transient, and reversible left ventricular systolic dysfunction triggered by stress, with endothelial dysfunction being one of its pathophysiological mechanisms. …”
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Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia by Taonga Musonda, Mildred Zulu, Mulemba Samutela, Annie Kalonda, Hamakwa Mantina, Pauline Okuku, Musalula Sinkala, Panji Nkhoma

“…There was a high prevalence of asymptomatic UTIs among SCA patients at UTH, which, when coupled with the marked leukocytosis and anaemia, may negatively impact the clinical outcome of the patients. …”
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Dynamic EIT technology for real-time non-invasive monitoring of acute pulmonary embolism: a porcine model experiment by Junyao Li, Mingxu Zhu, Yitong Guo, Weichen Li, Qing He, Yu Wang, Yuxuan Liu, Benyuan Liu, Yang Liu, Weice Wang, Zhenyu Ji, Xuetao Shi

“…In particular, the perfusion area on the side of the embolism is markedly diminished, and the absolute values of all perfusion indicators are significantly reduced. …”
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Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption by Yue Xu, Xiuying Xiao, Chunxiao Ma, Ziyi Wang, Wenxin Feng, Hanyu Rao, Wei Zhang, Ningyuan Liu, Rebiguli Aji, Xiangjun Meng, Wei‐Qiang Gao, Li Li

“…Significantly, supplementation with taurine markedly alleviated the symptoms of NSD2 deficiency‐induced IBD. …”
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Last-millennium volcanic forcing and climate response using SO₂ emissions by L. R. Marshall, L. R. Marshall, L. R. Marshall, A. Schmidt, A. Schmidt, A. Schmidt, A. P. Schurer, N. L. Abraham, N. L. Abraham, L. J. Lücke, R. Wilson, K. J. Anchukaitis, G. C. Hegerl, B. Johnson, B. L. Otto-Bliesner, E. C. Brady, M. Khodri, K. Yoshida

“…In UKESM1, we find that the simulated volcanic forcing differs considerably from the PMIP4 dataset used in models without interactive aerosol schemes, with marked differences in the hemispheric spread of the aerosol, resulting in lower forcing in the NH when <span class="inline-formula">SO₂</span> emissions are used. …”
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Lateral Extra-Articular Tenodesis as an Adjunct to ACL Reconstruction by Madeline M. McGovern MD, Sercan Yalcin MD, Natalie A. Lowenstein MPH, Jillian L. Mazzocca BA, Elizabeth G. Matzkin MD, Giovanna Medina MD, PhD

“…Anatomic landmarks are identified and marked. A 5-cm incision is made in line with the iliotibial (IT) band from Gerdy's tubercle toward the lateral epicondyle. …”
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PLGA-based biocompatible nanoparticles improved anti-breast tumor efficacy of 1,25(OH)2D3 through the SOCS3/STAT3/EMT signaling axis by JinJing Pan, Ping Wang, Linghong Xiong, Wenqing Yang, Jie Li, Kai Yang, Bingyan Li

“…Considering that epithelial-mesenchymal transition (EMT) is downstream of the SOCS3/STAT3/PI3K pathway, our findings also revealed that 1,25(OH)2D3 markedly regulated the expression of EMT markers. Additionally, the inhibitor of STAT3 exhibited inhibitory effects on EMT progression in breast cancer cells. …”
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Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

“…In 153 patients with severe liver fibrosis caused by hepatitis C virus (genotype 1), on background of triple AVT with telaprevir high level of immediate virologic response and low level of the preterm treatment discontinuation was marked.…”
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Perfusion index as a predictor of successful PNS-guided supraclavicular block: A prospective study by Monika Gandhi, Khushboo Ranpise, Aseem Sharma, Manish Banjare

“…Conclusion: The PI and PI ratio, particularly at the 10-minute mark, serve as reliable, non-invasive indicators of successful PNS-guided supraclavicular brachial plexus blocks. …”
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Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis by Sergio Bergese, Richard Berkowitz, Paul Rider, Martin Ladouceur, Suzanne Griffith, Alvaro Segura Vasi, Kristina Cochrane, Linda Wase, Mark A. Demitrack, Ashraf S. Habib

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Hubungan Berbagai Faktor Risiko Terhadap Kejadian Penyakit Jantung Koroner Pada Penderita Diabetes Melitus Tipe 2 by Fadma Yuliani, Fadil Oenzil, Detty Iryani

“…Conclusion: There are marked significant (p&lt;0,0001) relationship between gender, dyslipidemia, and smoking habit with CHD incident in DM patients and significant relationship (p&lt;0,05) between long-suffering diabetes, hypertension, and obesity with CHD incident in DM patients.…”
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Recombinant factor VIIa: new insights into the mechanism of action through product innovation by Miguel A. Escobar, Maureane Hoffman, Giancarlo Castaman, Cedric Hermans, Johnny Mahlangu, Johannes Oldenburg, Charles L. Percy, Mark T. Reding, Amy D. Shapiro, Steven W. Pipe

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Patient and tumor factors contributing to distant metastasis in well-differentiated thyroid cancer: a retrospective cohort study by Usman Khan, Ayham Al Afif, Abdullah Aldaihani, Colin MacKay, Matthew H. Rigby, Murali Rajaraman, Syed Ali Imran, Martin J. Bullock, S. Mark Taylor, Jonathan R. B. Trites, Robert D. Hart

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Adolescent Youth Survey on HIV Prevention and Sexual Health Education in Alabama: Protocol for a Web-Based Survey With Fraud Protection Study by Henna Budhwani, Ibrahim Yigit, Josh Bruce, Christyenne Lily Bond, Andrea Johnson

“…Adolescence is a period marked by exploration, risk taking, and learning, making comprehensive sexual health education a high-priority prevention strategy for HIV and sexually transmitted infections. …”
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