Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023 by Shuying Wang, Yifan Wang, Yingxue Zou, Cheng-liang Yin

“…The incidence of RSV exhibits marked seasonality and is influenced by various meteorological factors, which vary across regions and climates. …”
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Circadian Clock Gene Bmal1: A Molecular Bridge from AKI to CKD by Songyuan Yang, Zehua Ye, Lijia Chen, Xiangjun Zhou, Wei Li, Fan Cheng

“…Thus, implementing early interventions to halt the progression from AKI to CKD has the potential to markedly improve patient outcomes. Although considerable research has been conducted, the exact mechanisms linking AKI to CKD are complex, and effective treatments remain limited. …”
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Multiomics unravels the complexity of male obesity: a prospective observational study by Georgios E. Papadakis, Lucie Favre, Yassine Zouaghi, Nathalie Vionnet, Nicolas J. Niederländer, Michela Adamo, James S. Acierno, Dassine Berdous, Alexia Boizot, Jenny Meylan, Julijana Ivanisevic, Emmanuelle Paccou, Hector Gallart-Ayala, Tim Reyns, Elise Van Caeneghem, Bruno Lapauw, Jérôme Pasquier, Yasser Aleman, Styliani Mantziari, Olivier Salamin, Raul Nicoli, Tiia Kuuranne, Tom Fiers, Patric Hagmann, Federico Santoni, Andrea Messina, Nelly Pitteloud

“…Following RYGB-induced substantial weight loss, testosterone levels markedly increased in both obese individuals with and without HH, challenging the current definition of hypogonadism. …”
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Woody Species Composition, Structure, and Soil Seed Bank of the Degraded Parts of the Gera Moist Afromontane Forest, Southwestern Ethiopia by Dereje Egeta, Giche Yadesa, Abeje Eshete, Hailu Belay, Urge Charu, Tensay Teshome

“…Another five subplots were also marked for soil seed bank data collection that are 9 cm deep and 15 cm wide. …”
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Density-Driven CO₂ Dissolution in Depleted Gas Reservoirs with Bottom Aquifers by Xiaocong Lyu, Fang Cen, Rui Wang, Huiqing Liu, Jing Wang, Junxi Xiao, Xudong Shen

“…The findings elucidate that the temporal evolution of the Sherwood number observed in the synthetic model incorporating CTZ closely parallels that of the single-phase model, but the order of magnitude is markedly higher. The introduction of CTZ serves to augment gravity-induced convection and expedites the dissolution of CO₂, whereas the presence of residual-gas mixtures exerts a deleterious impact on mass transfer. …”
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Thyroid response to blocking sympathetic activity in chronic cold-exposed hunters in East Greenland: a case–control study by Mette Motzfeldt Jensen, Charlotte Elberling Almasi, Hans Christian Florian-Sørensen, Stine Linding Andersen, Stig Andersen

“…The fT3/fT4 ratio showed a continuous and marked decrease. Conclusion: We speculate that when blocking the sympathetic system, TSH increases to uphold the production of T3 needed for maintaining BAT activity. …”
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Ultraviolet B (UVB) Radiation Induces Skin Alterations, Emperipolesis and Decreases the Erythroid-to-myeloid Ratio in Rats by Verda Farida, Dion Adiriesta Dewananda, Muhammad Novrizal Abdi Sahid, Siti Isrina Oktavia Salasia

“…RESULTS: Erythema appeared on the skin as marked by orange-red spots. There were hyperkeratosis and pigment accumulations in the skin of UVB-irradiated group. …”
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Haemophagocytic Lymphohistiocytosis with Leptospirosis: A Rare but Devastating Complication by B. M. Munasinghe, A. G. Arambepola, N. Pathirage, U. P. M. Fernando, N. Subramaniam, S. Nimalan, T. Gajanthan

“…Bone marrow biopsy and markedly elevated serum ferritin and triglyceride levels done on day 10 (with unresolving fever, hepatosplenomegaly, and pancytopaenia) confirmed the diagnosis of HLH. …”
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<i>Weizmannia coagulans</i> BC99 Attenuates Oxidative Stress Induced by Acute Alcoholic Liver Injury via Nrf2/SKN-1 Pathway and Liver Metabolism Regulation by Ying Wu, Cheng Li, Yinyin Gao, Jie Zhang, Yao Dong, Lina Zhao, Yuwan Li, Shaobin Gu

“…The protective effects of BC99 were markedly diminished in the <i>skn-1</i> mutant (GR2245) and <i>daf-16</i> mutant (CF1038), further confirming the pivotal roles of SKN-1 and DAF-16 pathways in BC99-mediated antioxidant protection. …”
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The effect of failed transfer of passive immunity and agammaglobulinemia on the occurrence of preweaning diarrhea, pneumonia, and mortality in Holstein calves by Mely T. Olivera, Jesús Mellado, José E. García, Juan A. Encina, Perpetuo Álvarez, Ulises Macías-Cruz, Leonel Avendaño, Miguel Mellado

“…These diseases alone or co-occurring in the calves markedly increase preweaning mortality. …”
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Nonlinear relationship between hepatic steatosis index and reversion to normal glucose regulation in Chinese adults with prediabetes by Haiyong Zeng, Fei Yu, Haofei Hu, Yong Han, Ruixue Ye, Changchun Cao

“…Below this threshold, a strong negative association was observed, markedly enhancing the probability of returning to normoglycemic status (HR = 0.91, 95% CI: 0.88–0.94, P < 0.0001). …”
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Altered Expression of Hematopoiesis Regulatory Molecules in Lipopolysaccharide-Induced Bone Marrow Mesenchymal Stem Cells of Patients with Aplastic Anemia by Chandra Prakash Chaturvedi, Naresh Kumar Tripathy, Ekta Minocha, Akhilesh Sharma, Khaliqur Rahman, Soniya Nityanand

“…The BM-MSCs of AA patients as compared to controls had markedly lower expression of MIP-1α transcripts (p<0.001), higher expression of TNF-α (p<0.001), G-CSF (p<0.001), and SDF-1α (p<0.01) transcripts, and no difference in the expression of SCF and TGF-β transcripts. …”
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Associations between physical activity and heart disease among middle-aged and older Chinese adults by Yujia Liu, Chaoqun Yuan, Tong Chen, Linlin Zhou, Gengyin Zhu, Yu Chen

“…As PA increased to 4,000 METs-min/week, HD risk in the overall population decreased by approximately 26%, while further increases in PA did not produce any further marked reduction in the risk. A vigorous intensity of PA was associated with a reduced risk of HD and is strongly recommended.…”
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Attitudes towards transjugular intrahepatic portosystemic shunt (TIPS) in Australia: a national survey of TIPS centres by Jacob George, Avik Majumdar, Golo Ahlenstiel, Stuart K Roberts, Scott Read, Eric Kalo

“…More than half of respondents (56.5%) did not have institutional clinical practice protocols. There was marked variation in practices across institutions in terms of TIPS indications and patient selection. …”
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Global and Regional Burden of Type 2 Diabetes Mellitus Attributable to Low Physical Activity From 1990 to 2021 by Lihang Yang, Diya Xie, Fengmin Liu, Jiaying Lin, Xin Lin, Yuquan Chen, Kun Zhang

“…Conclusion Between 1990 and 2021, there was a marked rise in the global burden of T2DM associated with LPA. …”
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The Solar and Geomagnetic Storms in 2024 May: A Flash Data Report by Hisashi Hayakawa, Yusuke Ebihara, Alexander Mishev, Sergey Koldobskiy, Kanya Kusano, Sabrina Bechet, Seiji Yashiro, Kazumasa Iwai, Atsuki Shinbori, Kalevi Mursula, Fusa Miyake, Daikou Shiota, Marcos V. D. Silveira, Robert Stuart, Denny M. Oliveira, Sachiko Akiyama, Kouji Ohnishi, Vincent Ledvina, Yoshizumi Miyoshi

“…The ICMEs induced exceptional geomagnetic storms, peaking at a provisional Dst index of −412 nT at 2 UT on May 11, marking the sixth-largest storm since 1957. The AE and AL indices showed great auroral extensions that located the AE/AL stations into the polar cap. …”
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The mitigating effect of a topical preparation of amlodipine on imiquimod-induced psoriasis-like lesion in mice Authors by Zainab A. Mahdi, Fouad K. Gatea, Omeed M. Hassan, Zeena A. Hussein

“…Results: Topical amlodipine ointment markedly reduced the inflammatory signs of psoriatic lesions, and histopathological inspection confirmed these findings. …”
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Subtype-specific human endogenous retrovirus K102 envelope protein is a novel serum immunosuppressive biomarker of cancer by Qinyuan Gong, Qinyuan Gong, Rongzhen Xu, Rongzhen Xu

“…In contrast, K102-Env markedly increased in patients with PDAC, hepatocellular carcinoma (HCC), and non-small cell lung cancer (NSCLC) compared with healthy controls. …”
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Urine metabolic profile in rats with arterial hypertension of different genesis by A. A. Sorokoumova, A. A. Seryapina, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, М. А. Gilinsky, А. L. Markel

“…Changes in the content and ratio of metabolites in the sample mark the corresponding pathogenetic mechanisms by highlighting them, which is especially important for such a multifactorial disease as arterial hypertension. …”
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Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve by Yuming Huang, Kang Xu, Tingwen Zhou, Peng Zhu, Nianguo Dong, Jiawei Shi

“…In addition, runt-related transcription factor 2 and Ki-67 proteins were also markedly upregulated in VDSCs, whereas there was less expression of the focal adhesion genes integrin alpha and laminin alpha in VDSCs compared to VICs. …”
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