Plasma circulating cell–free DNA integrity and relative telomere length as diagnostic biomarkers for Parkinson’s disease and multiple system atrophy: a cross-sectional study by Chao Ying, Chao Han, Yuan Li, Mingkai Zhang, Shuying Xiao, Lifang Zhao, Hui Zhang, Qian Yu, Jing An, Wei Mao, Yanning Cai

“…The results showed that cell-free DNA integrity was significantly elevated in both Parkinson’s disease and multiple system atrophy patients compared with normal controls (P < 0.001 for both groups), whereas cell-free DNA relative telomere length was markedly shorter (P = 0.003 for Parkinson’s disease and P = 0.010 for multiple system atrophy). …”
Get full text

Petrophysical assessment of the Hammam Faraun, Matulla and Nubia Reservoirs in the Ashrafi Oil Field, Gulf of Suez by Mohammed Amer, Walid M. Mabrouk, Amr M. Eid, Ahmed Metwally

“…In contrast, the Nubia Formation, characterized by its uniform sandstone composition, has an effective porosity of approximately 0.18 and a consistent water saturation level of about 0.24, with net pay thicknesses between 72 and 155 ft, marking it as an important target for hydrocarbon exploration. …”
Get full text

The International Vitreoretinal B-Cell Lymphoma Registry: a protocol paper by David J Wilson, Valérie Touitou, Justine R Smith, Manabu Mochizuki, Hiroshi Takase, Steven Yeh, Alexandra L Farrall, H Nida Sen, Daniel V Vasconcelos-Santos, Joke H de Boer, Ninette H ten Dam-van Loon, Janet L Davis, Anthony J Hall, Mark H B Radford

Get full text

Can screening for degenerative cervical myelopathy (SCREEN-DCM) be effectively undertaken based on signs, symptoms and known risk factors? Rationale and research protocol for a pro... by Benjamin Davies, Mark Kotter, Granit Molliqaj, Enrico Tessitore, Karl Schaller, Teresa Somma, Aria Nouri, Renato Gondar, Joseph S Cheng, Paolo Cappabianca, Alexandre Lavé, Gianpaolo Jannelli, Allan Martin, Justin Virojanapa, Carmen L A Vleggeert-Lankamp, Valerie ter Wengel, Torstein Meling

Get full text

Are Saudi Radiological Sciences Students Prepared for Emergencies? Exploring Knowledge, and Attitudes Towards Basic Life Support and Cardiopulmonary Resuscitation by Alshamrani KM, Alkhayyat AA, Arif RN, Alahmadi AAS, Aldahery ST, Alsharif WM, Qurashi AA

“…Descriptive statistics were generated, and chi-square test examined associations between categorical variables and Basic Life Support (BLS) training status.Results: Out of 367 students contacted, 261 participated (71.1% response rate). BLS training markedly enhances knowledge of the correct chest compression rate, with 50.9% of trained students demonstrating accurate understanding compared to 27.5% of untrained students (P < 0.0001). …”
Get full text

Safety and efficacy of switching from adalimumab to sarilumab in patients with rheumatoid arthritis in the ongoing MONARCH open-label extension by Gerd R Burmester, Mark C Genovese, Vibeke Strand, Gregory St John, Andrea Rubbert-Roth, Howard Amital, Tatiana Raskina, Antonio Gómez-Centeno, Claudia Pena-Rossi, Leon Gervitz, Karthinathan Thangavelu, Susan Boklage

Get full text

Harnessing Non-Antibiotic Strategies to Counter Multidrug-Resistant Clinical Pathogens with Special Reference to Antimicrobial Peptides and Their Coatings by Shyam Kumar Mishra, Tanzina Akter, Umme Laila Urmi, George Enninful, Manjulatha Sara, Jiawei Shen, Dittu Suresh, Liangjun Zheng, Elias Shiferaw Mekonen, Binod Rayamajhee, Francesco M. Labricciosa, Massimo Sartelli, Mark Willcox

Get full text

Spatial and Temporal Variations in 94-GHz Radar Backscatter From a Springtime Snowpack by William D. Harcourt, Duncan A. Robertson, David G. Macfarlane, Brice R. Rea, Mike R. James, Mark Diggins, Blair Fyffe

Get full text

Tisser dans le désert : interactions et adaptations autour d’un ouvroir missionnaire au Mzab (1892-1950) by Mélina Joyeux

“…Despite the support of the colonial authorities, their first approach to the local population was marked by misunderstanding and confrontation. Missionary action therefore focused on minorities, quickly nullifying the initial apostolic strategy.At the dawn of the 20th century, the mission was reorganized to place the workshop at the heart of the missionary works. …”
Get full text

Modeling future climate change impacts on sorghum (Sorghum bicolor) production with best management options in Amhara Region, Ethiopia by Adem Mohammed, Abebe Misganaw

“…Historical daily weather data (1981–2010) of rainfall, maximum temperature, minimum temperature, and solar radiation were obtained from the nearest weather stations at Sirinka and Kombolcha while future climate date for 2030s and 2050s were downloaded from the ensemble of 17 CMIP5 GCM outputs run under RCP4.5 and RCP8.5 downscaled to the study sites using MarkSim. Different sowing dates, nitrogen rates, and supplemental irrigation were evaluated for their effectiveness to increase sorghum yield under the present and future climate conditions of the study area. …”
Get full text

Burden of diseases attributable to excess body weight in 204 countries and territories, 1990–2019 by Saeid Safiri, Jessica A. Grieger, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Seyed Aria Nejadghaderi, Asra Fazlollahi, Mark J. M. Sullman, Nahid Karamzad, Fikrettin Sahin, Kuljit Singh, Gary S. Collins, Ali-Asghar Kolahi

Get full text

Understanding Health-Related Discussions on Reddit: Development of a Topic Assignment Method and Exploratory Analysis by Garrett J Chan, Mark Fung, Jill Warrington, Sarah A Nowak

Get full text

Designing an online intervention for adults with addictive eating: a qualitative integrated knowledge translation approach by Phillipa Hay, Amanda L Baker, Clare Collins, Tracy Burrows, Mark Leary, Kirrilly Pursey, Antonio Verdejo-García, Janelle Skinner, Megan C Whatnall

Get full text

Field Detection and Numerical Simulation Study on Roof Asymmetric Fracture Mechanism of Large-Span Soft Rock Roadway with Discontinuity Surface by Liang Chen, Shouyang Gao, Bin Miao, Nan Yao, Shizhong Zhang, Wei Zhang

“…The roadway roof presents a markedly asymmetric caving feature. (3) With the increase of discontinuity surface angles, the roof fracture range gradually decreases in region I and increases in region II as well as the structural features of roof pressure-bearing arch transform from “left-low right-high continuous asymmetric structure” (30°-60°) to “left-low right-high discontinuous asymmetric structure” (90°) to “unilateral partial pressure-bearing arch structure” (120°-150°). …”
Get full text

Associations of substance use and positive coping behaviors with sleep quality during the COVID-19 pandemic by Jessica Laudie, Bethany L. Stangl, Tommy Gunawan, Tommy Gunawan, Melanie L. Schwandt, Cecilia Cheng, Amanda K. Gilmore, Amanda K. Gilmore, David Goldman, David Goldman, Vijay A. Ramchandani, Nancy Diazgranados, Jeremy W. Luk

Get full text

How long does it take to start minimal enteral feeding in preterm Neonates admitted to NICUs in Southern Oromia, Ethiopia? by Anteneh Fikrie, Terefu Yambo, Alo Edin, Miesa Gelchu, Dejene Hailu, Mark Spigt

Get full text

Correlation Between the Ratio of Uric Acid to High-Density Lipoprotein Cholesterol (UHR) and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus:A Cross-Sectional Study by Wang L, Liu L, Luo H, Wu Y, Zhu L

“…We gathered demographic and clinical data, calculated UHR, and explored its correlation with DR development.Outcomes: Individuals diagnosed with diabetic retinopathy (DR) exhibited a markedly elevated uric acid to high-density lipoprotein cholesterol (UHR) ratio when contrasted with those without DR (NDR), achieving statistical significance with a P-value below 0.001. …”
Get full text

Cross-cultural adaptation and psychometric properties of the Chinese version of the Orthorexia Nervosa Inventory by Xinzhang Sun, Ying Lu, Chengping Jian, Hanqing Zhang, Hanqing Zhang

“…BackgroundOrthorexia nervosa refers to an unhealthy preoccupation with maintaining a perfect diet, which is marked by highly restrictive eating habits, rigid food rituals, and the avoidance of foods perceived as unhealthy or impure. …”
Get full text

Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle by Sarah Damery, Kerry Allen, Lisa Dikomitis, Harry Hill, David Coyle, Maatla Tshimologo, Mark Lambie, Simon J Davies, Iestyn Williams, James Fotheringham, Louise Phillips-Darby, Ivonne Solis-Trapala

Get full text

Activity of Antiseptics Against <i>Pseudomonas aeruginosa</i> and Its Adaptation Potential by Tomasz M. Karpiński, Marzena Korbecka-Paczkowska, Mark Stasiewicz, Aleksandra E. Mrozikiewicz, Donald Włodkowic, Judyta Cielecka-Piontek

Get full text