Combined Effects of 2-Methoxyestradiol (Hypoxia-Inducible Factor 1α Inhibitor) and Dasatinib (A Second-Generation Tyrosine Kinase Inhibitor) on Chronic Myelocytic Leukemia Cells by Yuexian Zhang, Heng Chen, Yunfeng Shen, Xin Zhou

“…Inhibition of this gene could markedly increase cell apoptosis in a dose-dependent fashion. …”
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Role of Epigenetics in Modulating Phenotypic Plasticity against Abiotic Stresses in Plants by Fayaz Ahmad Dar, Naveed Ul Mushtaq, Seerat Saleem, Reiaz Ul Rehman, Tanvir Ul Hassan Dar, Khalid Rehman Hakeem

“…Epigenomics refers to the large-scale study of epigenetic marks on the genome, which include covalent modifications of histone tails (acetylation, methylation, phosphorylation, ubiquitination, and the small RNA machinery). …”
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Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery by Celien Bollen, Sofie Louwagie, Femke Deroover, Wouter Duverger, Ladan Khodaparast, Laleh Khodaparast, Dieter Hofkens, Joost Schymkowitz, Frederic Rousseau, Liselot Dewachter, Jan Michiels

“…Our data support a model in which aggregate structure, rather than cellular activity, marks the transition from the persister to the VBNC state.…”
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Spatio-temporal characteristics and analysis of influencing factors of inclusive green growth in China’s oil and gas resource industry by Xiangyu Sun, Yanqiu Wang

“…This study introduces a novel index system for inclusive green growth (IGG) specific to China’s oil and gas resource industry, encompassing dimensions such as industrial development, social equity in opportunities, poverty and income inequality reduction, and green ecology. This research marks the first application of the CRITIC combined weighting-TOPSIS model to assess inclusive green growth in the oil and gas resource industry (IGGOG) across 30 Chinese provinces from 2012 to 2021. …”
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Cardiovascular reactivity and prediction of the high blood pressure in the community. by Mikhail Benet Rodríguez, Liliana J Espinosa Chang, Juan José Apollinaire Pennini, Milagros L León Regal, María Felicia Casanova González

“…<strong>Results:</strong> The incidence of hypertension in the cohort of HRC was of 34,15/100 people and in the CNR of 10,24/100 people chi square = 13,3 GL= 1 P= 0,007, on the other hand, when we made adjustments according to different cardiovascular risk markers to determine the relationship between hypertension and hyperreactivity, it was observed that the relationship exists in spite of the risk marks mentioned before. <strong>Conclusions:</strong> The individuals whit HRC determined by the SWT have a risk to develop higher significant sustained hypertension then the cardiovascular normorreactivos ones this is an evidence that this method is useful to predict HBP.…”
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A Multi-Faceted Approach to Trending Topic Attack Detection Using Semantic Similarity and Large-Scale Datasets by Insaf Kraidia, Afifa Ghenai, Samir Brahim Belhaouari

“…Twitter&#x2019;s widespread popularity has made it a prime target for malicious actors exploiting trending hashtags to disseminate harmful content. This study marks the first systematic exploration of semantic consistency in tweets to detect trending topic attacks. …”
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Innovative Design of External Airbag System for Improved Automotive Safety by A. Elaidy, R. Rayner, C. Kalyvas

“…The introduction of the innovative external airbag system marks a significant advancement in pedestrian safety within the realm of road accidents. …”
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Nonlinearity of the post-spinel transition and its expression in slabs and plumes worldwide by Junjie Dong, Rebecca A. Fischer, Lars P. Stixrude, Matthew C. Brennan, Kierstin Daviau, Terry-Ann Suer, Katlyn M. Turner, Yue Meng, Vitali B. Prakapenka

“…The post-spinel transition marks the upper–lower mantle boundary, where ringwoodite dissociates into bridgmanite plus ferropericlase, and its Clapeyron slope regulates mantle flow across it. …”
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Nonlinear memristive computational spectrometer by Xin Li, Jie Wang, Feilong Yu, Jin Chen, Xiaoshuang Chen, Wei Lu, Guanhai Li

“…This combination enables our spectrometer to achieve an exceptional peak wavelength accuracy of 0.18 nm and a spectral resolution of 2 nm within the 630–640 nm range. This development marks a significant advancement in the creation of compact, high-efficiency spectroscopic instruments and offers a versatile platform for applications across diverse material systems.…”
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A Comprehensive Genetic Analysis of Mycotoxin-Producing Penicillium expansum Isolated from River Water Using Molecular Profiling, DNA Barcoding, and Secondary Structure Prediction by R. Ravikiran, G. Raghu and B. Praveen

“…This study marks the first report on the genetic characterization of Penicillium expansum strain capable of mycotoxin production isolated from river water. …”
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XGBoost-enhanced ensemble model using discriminative hybrid features for the prediction of sumoylation sites by Salman Khan, Sumaiya Noor, Tahir Javed, Afshan Naseem, Fahad Aslam, Salman A. AlQahtani, Nijad Ahmad

“…XGBoost-Sumo achieved an impressive accuracy of 99.68% on benchmark datasets using 10-fold cross-validation and 96.08% on independent samples. This marks a significant improvement, outperforming existing models by 10.31% on training data and 2.74% on independent tests. …”
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Parkinsonian Rigidity Shows Variable Properties Depending on the Elbow Joint Angle by Takuyuki Endo, Toshimitsu Hamasaki, Ryuhei Okuno, Masaru Yokoe, Harutoshi Fujimura, Kenzo Akazawa, Saburo Sakoda

“…We first measured muscle tone at the elbow joint in 20 healthy subjects and demonstrated that an angle of approximately 60° of flexion marks the division of two different angle-torque characteristics. …”
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On-site quantitative detection of fentanyl in heroin by machine learning-enabled SERS on super absorbing metasurfaces by Yingkun Zhu, Haomin Song, Ruiying Liu, Yunyun Mu, Murali Gedda, Abdullah N. Alodhay, Lei Ying, Qiaoqiang Gan

“…Incorporation of partial least squares regression into our analysis achieved over 93% accuracy in concentration predictions, eliminating the need for pre-data processing or specialized personnel. This marks a key advancement in rapid, accurate fentanyl detection, aiding the fight against the opioid crisis and improving public health safety.…”
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Cretaceous-Tertiary Foraminifera and Palynomorphs from Djega Section and Inferred Paleodepositional Environments, Rio Del Rey Basin, Cameroon, West Africa by Njon Olivier Anoh, Mbanda L. Njoke, Ngoe D. Elangwe

“…This indicates a general fall in sea level during the Early Paleocene earlier reported within this subregion, and the boundary marks the start of the out building of the Niger Delta which the Tertiary Rio del Rey Basin is part of. …”
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Magnetic Resonance Imaging Techniques for Post-Treatment Evaluation After External Beam Radiation Therapy of Prostate Cancer: Narrative Review by Eleni Bekou, Admir Mulita, Ioannis Seimenis, Athanasia Kotini, Nikolaos Courcoutsakis, Michael I. Koukourakis, Francesk Mulita, Efstratios Karavasilis

“…<b>Conclusions</b>: The integration of advanced MRI technologies into clinical routine marks the beginning of a new era of BCR with accuracy.…”
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Economic Council of Mongolia: on the 100th Anniversary of its Establishment by Keemya V. Orlova

“…Introduction. 2024 marks the 100th anniversary of the founding of the Economic Council of Mongolia, the formation of which as part of the Ministry of Finance was adopted at a meeting of the People’s Government on November 18, 1924. …”
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Readiness of Christian Religious Education (CRE) Teachers and Implementation of Competence-Based Curriculum (CBC) in Nyakabande Sub-county Kisoro District. by Mugwaneza, Allen

“…The Competence-Based Curriculum (CBC) introduced in Uganda marks a significant shift in the educational landscape, prioritizing the development of practical skills and competencies over traditional knowledge acquisition. …”
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Gender differences in response to warrelated trauma and posttraumatic stress disorder – a study among the Congolese refugees in Uganda by Herbert, E. Ainamani, Thomas, Elbert, David Kani, Olema, Tobias, Hecker

“…Background: The wars in the Democratic Republic of Congo have left indelible marks on the mental health and functioning of the Congolese civilians that sought refuge in Uganda. …”
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Methods of massive parallel reporter assays for investigation of enhancers by S. E. Romanov, D. A. Kalashnikova, P. P. Laktionov

“…In combination with high-throughput studies focused on the genome-wide distribution of epigenetic marks, regulatory proteins and the spatial structure of chromatin, this significantly expands the understanding of the principles of epigenetic regulation of genes and allows potential regulatory elements to be searched for in silico. …”
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Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy by Jūratė Savickienė, Sandra Baronaitė, Aistė Zentelytė, Gražina Treigytė, Rūta Navakauskienė

“…These differences correlated with changes in the level of chromatin modifiers (DNMT1 and HDAC1) and polycomb group proteins (EZH2, SUZ12, and BMI1) paralleling with changes in the expression of repressive histone marks (H3K9me3 and H3K27me3) and stemness markers (Oct4, Nanog, Sox2, and Rex1). …”
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